The application relates to a novel FSP1 degrading agent PROTAC compound and a preparation method and application thereof, and belongs to the technical field of
medicinal chemistry. The novel FSP1 degrading agent PROTAC compound is a compound shown in formula I, a pharmaceutically acceptable salt of the compound shown in formula I, a
hydrate of the compound shown in formula I or a solvate of the compound shown in formula I. The novel FSP1 degrading agent PROTAC compound provided in the application has the activity of degrading
ferroptosis inhibitor 1 (FSP1).