47results about How to "Rich biological activity" patented technology

The invention discloses a green health-preservation sweet-scented osmanthus tea beverage. The green health-preservation sweet-scented osmanthus tea beverage comprises the following raw materials in parts by weight: 30-40 parts of sweet-scented osmanthus, 1-2 parts of honey, 3-5 parts of Chinese wolfberry fruits, 7-11 parts of fresh tea leaves, 2-3 parts of haws, 3-5 parts of sugarcane, 2-4 parts of cucumbers,3-5 parts of aloe, 0.08-0.14 part of a thickening agent, 0.01-0.03 part of an antioxidant stabilizing agent, 0.1-0.3 part of a vitamin additive and 12-16 parts of distilled water. The sweet-scented osmanthus tea beverage disclosed by the invention has the functions of clearing heat, removing toxicity, moisturizing the intestines, regulating the function of the stomach, regulating vital energy and nourishing the lungs, and is mellow in mouth feel, moderate in sour and sweet degrees, delicious, pleasant in delicate fragrance, high in nutrient value; in addition, the beverage does not precipitate and is good in color singleness; and besides, through the preparation method of the green health-preservation sweet-scented osmanthus tea beverage disclosed by the invention, sweet-scented osmanthus blooming seasonal restrictions are avoided, the green health-preservation sweet-scented osmanthus tea beverage can be processed in an all-weather manner, the raw materials are non-toxic, harmless and convenient to obtain, and the green health-preservation sweet-scented osmanthus tea beverage is low in cost and simple in technology and has higher use value and favorable application prospects.

The invention discloses a method for preparing tangerine whole-fruit superfine powder and the tangerine whole-fruit superfine powder. The preparation method comprises the following steps: performing ozone washing treatment on tangerines; and sequentially performing coarse grinding, wet-processing superfine grinding, ultrasonic grinding, enzymolysis, colloid grinding and high-pressure homogenizingto obtain whole-fruit pulp having the grain size of 5-15mu m; and performing vacuum freezing and spray drying on the whole-fruit pulp to obtain the whole-fruit superfine powder. According to the preparation method, the problem that fibers, pectin and other macromolecules in peels and seeds of tangerine whole fruits are water insoluble can be effectively solved, complete utilization of tangerines can be realized, and nutritional ingredients can be furthest maintained; the stability of the superfine powder under a juice system can be realized by utilizing the pectin of tangerines; the effects ofoxidation resistance, inflammation resistance and the like can be enhanced due to functional ingredients including flavone, limonin, carotenoid and the like; and the tangerine whole-fruit superfine powder has rich fragrance, bright color, rich functional nutritional ingredients and good stability.

The present invention discloses a medical periosteum scaffold cooperatively constructed by ions and geometric pattern signals, and a construction method thereof. The medical periosteum scaffold comprises an inner surface fiber layer, an intermediate fiber layer and an outer surface fiber layer; the inner surface fiber layer is composed of wave-shaped, oriented and arranged loose porous fibers anda degradable and stretchable high polymer material, and provides geometric pattern signal delivery for the periosteum scaffold; the intermediate fiber layer is composed of latticed fibers and a degradable and stretchable high polymer material, and provides mechanical support for the periosteum scaffold; and outer surface fiber layer is composed of disordered and compact composite fibers and a degradable high polymer material and ion-doped biological ceramic micro-nano particles, and provides ion signal delivery for the periosteum scaffold. The construction of the bionic natural periosteum scaffold can be realized by combining the ions and geometric pattern signals, and the medical periosteum scaffold obtains functions of mechanics similar to natural periosteum, induction of bone componentregeneration and structure reconstruction, induction of angiogenesis and inhibition of bacterial proliferation, and helps injured part bone tissue repair and function stable reconstruction.

The invention discloses a TBJ tissue repair film type stent and a preparation method thereof. The TBJ tissue repair film type stent comprises three layers of regional structure with gradient changes:a polymer / ceramic composite material area, a polymer area and a polymer / ceramic composite material area. The preparation method comprises the following steps: firstly, obtaining the polymer film and the polymer / ceramic composite film through blending and hot-press molding, splicing the two films, carrying out hot-press fusion, and then performing axial mechanical stretching along the vertical direction of the interface of the connecting line to obtain the film type TBJ stent. The stent material is biomimics TBJ tissue in design, has multiple gradient characteristics of material component, structure and mechanical property changes, further has effects of mechanical enhancement and composite regulation of ion and mechanical signals, which is a tendon-bone repair stent material with high bionic tissue characteristics and excellent mechanical properties, and can be applied to regeneration induction and functional reconstruction of cells and extracellular matrixes in the tendon-bone junction.

The invention mainly relates to 3-aminobenzo[d]isothiazole and derivatives thereof and a synthetic method thereof. Benzamidine compounds and elemental sulfur are converted into 3-aminobenzo[d]isothiazole and the derivatives thereof only under the action of an alkali and in an air atmosphere without use of a catalyst during synthesis. The problems that a conventional synthetic method of a functionalized 3-aminobenzo[d]isothiazole compound has complex synthetic steps, requires a multistep synthesis process to complete, and also requires use of metal catalysts or peroxides, as well as has low yield or harsh reaction conditions are overcome. The synthetic method has the characteristics of simple reaction system, mild reaction conditions, less reaction equipment, simple experimental operation,wide sources of used materials, high yield, easy expanding of users and application, high utilization value of products, expectable prospects of commercialization of the market and the like.

The invention discloses a production method of barley leaf and wheat germ compound beverage. The production method is characterized by comprising the steps of taking barley leaves as raw materials, performing impurity removal, high pressure cleaning, purifying rinsing, artificial cleaning, cutting, leachating, withering, oxidative fermentation, evaporation and sizing, primary drying, secondary drying, magnetic sieving, excessive metal detection, cutting and crushing, water-cooling crushing and low-temperature wall breaking to prepare barley seedling powder, and then adding small-molecular wheat germ powder and mixing to prepare the solid beverage. According to the solution, by scientific combination of raw material components of barley leaves and wheat germs, the barley leaf and wheat germ resources are fully used, and the type of the barley leaf and wheat germ compound solid beverage is enriched; meanwhile, by the application of a modern food processing technology and a biological technology, the shortcomings in the prior art are overcome, and the beverage with the characteristics of nature, nutrition, convenience, safety, good taste and the like is prepared; people can eat the beverage frequently to fulfill the aims of nourishing the life and protecting the health.

The invention discloses a fermented green fruit and vegetable compound beverage. The fermented green fruit and vegetable compound beverage is prepared from the following raw materials in parts by weight: 10 to 14 parts of sugarcanes, 8 to 16 parts of cucumbers, 4 to 8 parts of oranges, 3 to 5 parts of aloes, 7 to 16 parts of strawberries, 7 to 14 parts of okras, 2 to 4 parts of carrots, 4 to 6 parts of water chestnuts, 0.1 to 0.25 part of a stabilizer, 0.08 to 0.14 part of a thickener, 0.01 to 0.03 part of an antioxidant, 0.1 to 0.3 part of a vitamin additive, 0.8 to 2.4 parts of a zymophyte mixed culture and 10 to 14 parts of water. According to the fermented green fruit and vegetable compound beverage, fruits and vegetables are reasonably matched and beneficial bacteria are added and are used for fermenting the fruits and the vegetables, so that nutrient components in fruit and vegetable juice and the immune regulation capability are greatly improved; the fermented green fruit and vegetable compound beverage has the effects of relaxing bowel, promoting diuresis and treating stranguria and clearing lung and eliminating phlegm; moreover, the beverage has no sediment, relatively good color and luster singleness and relatively high nutrient value; meanwhile, the adopted raw materials do not belong to medicinal materials so that the fermented green fruit and vegetable compound beverage is suitable for drinking for a long period and has no toxic or side effect and health of human bodies is easy to maintain; the raw materials are easy to obtain, the raw materials are low in cost and a process is simple, so that the fermented green fruit and vegetable compound beverage has relatively high practical value and a good application prospect.

The invention mainly relates to indolo [2, 3b] indole, a derivative thereof and a synthesis method thereof. According to the technical scheme, during synthesis, a metal catalyst is not required to beused, and a 2-(3-indolyl) cyclohexanone compound and an aniline compound are converted into a polysubstituted indolo [2, 3-b] indole derivative under the action of an iodine reagent and in an organicsolvent. According to the method, the problems that an existing synthesis method of the functionalized indolo [2, 3-b] indole compound is complex in synthesis step, a multi-step synthesis process needs to be adopted for completing the synthesis, a metal catalyst or peroxide needs to be used, and raw materials are difficult to prepare are solved; the atom economy is maintained to the greatest extent; and the derivative also has the characteristics of simple reaction system, mild reaction conditions, less reaction equipment, simple experimental operation, wide material sources, high yield, easyexpansion of users and application, high product utilization value, expectable market commercialization prospect and the like.

The invention relates to an areno [c] carbazoles derivative and a synthetic method thereof. According to the technical scheme, environmentally friendly and low-price ammonium iodide is used as a catalyst, 2,3-dichloro-5,6-dicyano benzoquinone as an oxidizing agent, a mixture of one or more of hexamethylene, toluene, dimethylbenzene, trimethylbenzene, benzotrifluoride, ethylbenzene, chlorobenzene,o-dichlorohenzene, anisole, decahydronaphthalene and 1,4-dioxane is used as an organic solvent, and simple raw materials including an indoles derivative, a cyclohexanones derivative and olefins derivative are synthesized into areno [c] carbazole and a derivative thereof in a pot. The shortcomings that by an existing synthetic method, when a metal catalyst or a metal oxidizing agent requires or a starting raw material with relatively high activity requires, synthesis steps are complicated, reaction conditions are severe and the like are overcome. The synthetic method is suitable for preparing the areno [c] carbazoles derivative with certain photoelectric property, bioactivity and drug activity.

The invention discloses a fresh flower and fruit health care tea, which comprises the following raw materials by weight: 3-5 parts of smallanthus sonchifolius powder, 10-20 parts of a fruit additive, 15-25 parts of a flower additive, 0.01-0.03 part of a stable quality preservation agent, 0.2-0.6 part of a vitamin additive, 10-20 parts of a health care additive, and 15-25 parts of water. The tea provided by the invention adopts a variety of natural fruits and fresh flowers as the main raw materials, and is rich in nutrition, multiple effective components reach a synergistic effect, and play a good role of resisting fatigue, whitening skin, nourishing facial appearance, clearing heat and cooling blood, helping produce saliva and slaking thirst, and conditioning stomach and intestine, and the added health care additive further improves the health care function. At the same time, the preparation method of the health care tea provided by the invention has the characteristics of low raw material cost and simple process, and has very high practical value and good application prospect.

The invention discloses crisp ginseng and a preparation method thereof, belongs to the technical field of ready-to-eat food, and solves the technical problems which the technical personnel of the field always want to solve but cannot solve, that is to say, how to provide healthy and crisp ginseng having the advantages of good taste, crisp taste and maximum preservation of nutritional ingredients and a preparation method thereof. The crisp ginseng is composed of 82-90 parts by weight of raw sun-dried ginseng or red ginseng, 8-12 parts by weight of honey and 2-6 parts by weight of hawthorn decoction pieces. The invention also provides the preparation method of the crisp ginseng. The crisp ginseng is crisp when being put in mouth, is moderate in sweet and sour, is capable of strengthening themiddle warmer, moistening dryness, promoting the secretion of saliva or body fluid and nourishing heart, enriches special ginsenoside active ingredients, and is suitable for wider population, especially for subhealthy people to eat. The preparation method has short in technological process and fast in speed, the product quality is stable and controllable, and the preparation method is suitable for industrialized production.

The invention relates to 3,4,5-trisubstituted-4,5-dihydroisoxazole, a derivative and a synthetic method and an application thereof. The invention mainly relates to a synthetic method of an isoxazoline compound. With adoption of a technical scheme that an aldehyde compound and oxime ester are converted into isoxazoline and the derivative thereof by taking an organic solvent as a solvent under the action of alkali without using a catalyst, the synthetic method solves the problem that an existing synthetic method of the isoxazoline compound is complicated in synthetic step, is accomplished by adopting multiple steps, and also needs a metal catalyst, a chemically equivalent metal oxidant or a peroxide. The atom economy is kept to the extreme extent; the isoxazoline compound has a stable molecular structure and an excellent chemical property, and molecular slices and compound segments contain rich contents with biological activity and pharmacological activity. The isoxazoline compound also has the characteristics of being simple in reaction system, mild in reaction condition, relatively less in reaction equipment, simple in experimental operation, wide in source of materials, high in yield, easy for expansion of user and application, relatively high in utilization value of product and expectable in market commercial prospect.

The invention belongs to the field of chemical synthesis, and particularly relates to a water-phase one-pot synthesis method of 3-flavonol and a 3-flavonol derivative. According to the method, 2-hydroxyacetophenone, 2-hydroxyacetophenone derivatives, benzaldehyde and benzaldehyde derivatives are used as reaction substrates, or 2-hydroxy-chalcone and hydroxy-chalcone derivatives are used as reaction substrates; water or ethanol water solution is used as a solvent; under the aerobic condition at 20 to 100 DEG C, reaction is performed to obtain the 3-flavonol and the 3-flavonol derivative. The invention provides a fire-new reaction mechanism, and develops a novel 3-flavonol synthesis method with the advantages of high efficiency, convenience, high speed and wide substrate adaptability. The invention also provides a fire-new 3-flavonol derivative synthesized by the novel method; important application values are realized in the field of medical care sanitation.

The invention discloses a mung bean beverage with effects of clearing heat and relieving summer heat. The mung bean beverage is prepared from the following raw materials in parts by weight: 80 to 90 parts of mung beans, 10 to 16 parts of traditional Chinese medicinal additive with the effect of clearing heat, 2 to 4 parts of Gufang brown sugar, 12 to 18 parts of green plant additive, 0.5 to 0.9 part of vitamin additive, 0.4 to 0.6 part of sodium citrate, 2 to 6 parts of white fungus, 2 to 4 parts of lotus seeds and 10 to 20 parts of fruit juice additive. The mung bean beverage has the functions of clearing away heat and toxic materials, relieving summer heat and restlessness, tonifying spleen, stopping diarrhea, supplementing the kidney to control the nocturnal, moistening lung to arrest cough, tranquilizing by nourishing the heart, reducing blood glucose, relieving a cough and engendering fluid; meanwhile, the preparation method has the advantages of adoption of environment-friendly and healthy raw materials, no additive, low cost, simple process, high practical value and good application prospect.

The invention discloses novel axially substituted silicon phthalocyanine, a method for preparing the same and application of the axially substituted silicon phthalocyanine to photodynamic therapy. The axially substituted silicon phthalocyanine is a 4-piperidine methoxy axially substituted silicon phthalocyanine derivative. The method includes adding silicon phthalocyanine dichloride, 4-piperidinemethanol and alkaline catalysts into organic solvents in a reactor with a reflux device in nitrogen atmosphere, and carrying out heating reflux reaction to obtain the 4-piperidine methoxy substituted silicon phthalocyanine. The novel axially substituted silicon phthalocyanine, the method and the application have the advantages that the axially substituted silicon phthalocyanine structurally contains 4-piperidine methoxy, synergistic effects can be realized by the axially substituted silicon phthalocyanine which is used as a photosensitizer during photodynamic therapy, the method for synthesizing the novel axially substituted silicon phthalocyanine is simple, and the problem of easiness in aggregation of phthalocyanine in physiological environments can be solved (owing to the low aggregation degree of the axially substituted silicon phthalocyanine); the axially substituted silicon phthalocyanine is good in photostability, is high in absorption in phototherapy windows (with the sizes of 600-900 nm), is high in singlet oxygen quantum yield and has PDT (photodynamic therapy) application potential.

The invention belongs to the technical field of medical chemistry, and particularly relates to a synthesis method and application of a chiral alpha-propargyl-3-indole compound and a derivative thereof, and the compound and the derivative thereof take a diazo compound, alcohol and indole propargyl alcohol as raw materials, Rh2 (esp) 2 and chiral phosphoric acid as catalysts, and a molecular sieve as a water absorbent, and are subjected to a one-pot reaction to prepare the chiral alpha-propargyl-3-indole compound. And carrying out a one-step three-component reaction in an organic solvent. The method disclosed by the invention has the advantages of high atom economy, good selectivity, mild reaction conditions, high yield, simplicity and safety in operation and the like. Moreover, the chiral alpha-propargyl-3-indole compound and the derivative thereof have a lot of biological activities, and the indole skeleton and the indolinone skeleton contained in the compound are important structural fragments of a lot of complex natural products with biological activities, so that the chiral alpha-propargyl-3-indole compound and the derivative thereof have a good application prospect. The compound can be used as an important intermediate of medicine and chemical industry, and has a wide application prospect in the field of medicine.

The invention discloses a preparation method and application of dahurian rose flower and fruit enzyme, wherein dahurian rose flower, dahurian rose fruit, dahurian rose leaf and dahurian rose seed which are just picked are used as raw materials, and the raw materials are pulped, filtered, adjusted in sugar degree, sterilized, fermented and filtered to obtain the dahurian rose flower and fruit enzyme. Desensitization treatment is carried out in the fermentation process, which avoids the pollen allergy condition of some people. The dahurian rose flower and fruit enzyme stock solution retains theactivity and function of the effective components to the maximum extent, has strong capability for removing superoxide anion free radical, hydroxyl free radical and DPPH free radical, meanwhile, the natural dahurian rose flower and fruit enzyme product has rich medicinal values, such as obvious anti-aging, anti-fatigue, anti-radiation, anoxia resistance and the like. The natural nutrient multifunctional precious resource is made into an enzyme product, and a new poverty-alleviation industrial chain is also found for poverty alleviation.

The invention provides a preparing method of a composition with natural sun screen performance. The preparing method comprises the steps that A-phase raw materials are sterilized, the temperature is adjusted to 75-85 DEG C, and stirring is conducted until the materials are dissolved and the mixture becomes transparent, wherein the A-phase raw materials comprise water and carbomer; B-phase raw materials are heated to 80-90 DEG C and stirred evenly, wherein the B-phase raw materials comprise one or two of glycerol monostearate and PEG-100 stearate and one or two of cetearyl olivate and sorbitanolivate; the B-phase raw materials and the A-phase raw materials are mixed evenly at 75-85 DEG C; homogeneous emulsification is conducted; C-phase raw materials are added and stirred evenly, wherein the C-phase raw materials comprise triethanolamine, a dendrobium officinale extract, a ginger extract, a magnoliae officmalis cortex extract and an angelicae sinensis radix extract. The preparing method is simple and easy to implement, and supercritical CO2 is adopted to extract natural plants, so that the extraction effect is good, and the preparing method is economical and environmentally friendly and saves energy. The prepared composition has high safety and high sun screen capacity.

The invention discloses a dihydrofuran quinolinone derivative and a preparation method thereof, relates to a dihydrofuran quinolinone derivative and a preparation method thereof, and aims to solve the technical problems of metal residues and tedious steps in the existing synthesis method of a dihydrofuran quinolinone compound. The structural formula of the dihydrofuran quinolinone derivative is shown in the specification, wherein R1 is alkoxy, halogen, alkyl, H or substituted aryl; and R2 is alkoxy, halogen, alkyl or H. The preparation method comprises the following steps: dissolving a 1, 7-eneyne substrate, ethyl bromodifluoroacetate, a photocatalyst and alkali in an organic solvent, uniformly mixing the mixture, carrying out an illumination reaction under a blue LEDs lamp, carrying out rotary evaporation on the solvent, and carrying out separation and purification to obtain the dihydrofuran quinolinone derivative. The compound can be used as a drug lead compound, and can be used in the fields of biological activity test research and synthesis.

The invention relates to the technical field of food processing, in particular to a compound fruit and vegetable fermented drink. The compound fruit and vegetable fermented drink is prepared from rawmaterials in parts by weight as follows: 15-18 parts of sugarcane, 20-30 parts of black tea, 1-3 parts of oranges, 2-6 parts of tea tree leaves, 2-5 parts of pears, 1-4 parts of chlorella powder, 3-6parts of zymocyte, 7-15 parts of strawberries, 0.1-0.2 parts of a thickener, 0.4-0.6 parts of a vitamin additive and the balance of purified water. The invention also relates to a preparation method of the compound fruit and vegetable fermented drink. The drink is derived from fresh fruits and vegetables, has uniform nutrients and rich bioactivity, meets demands of consumers with different nutrient needs, has reddish brown, bright and uniform color and uniform juice turbidity, has no impurities and has fine and soft taste, moderate sweetness and sweet aroma under the synergistic effect of allthe raw materials.

The invention discloses a beewax coating sandwich cake product and a manufacturing method thereof. The beewax coating sandwich cake product comprises, by weight, 0.50-2.50 parts of honey, 0.50-2.50 parts of bee pollen, 1.00-3.00 parts of beewax, 1.00-3.00 parts of anhydrous milk fat and 8-12 parts of two slice-shaped cake blocks. The manufacturing method comprises the steps of 1, choosing of materials, 2, leaching; 3, extracting; 4, preparing of coating ingredients; 5, power beating; 6, preparing of sandwich slurry; 7, preparing of sandwich; 8, coating; 9, cooling; 10, sealing. The honey product reserves an idea of product nutrition, health and healthcare, and the product is also endowed with the characteristics of being instant and convenient; the product has the natural and appropriate beewax fragrance, and is rich in nutrient, the sandwich slurry is moderate in viscosity, and the taste and the mouthfeel are appropriate.

The invention discloses a preparation method of freeze-dried powder of active factor of hair follicle stem cells for treating hair loss, belonging to the technical field of cytokines. And the preparation method includes the following steps: S1, acquisition of hair follicle stem cells; S2, acquisition of hair follicle stem cell active factors: inserting hair follicle stem cells into an expansion medium for subculture, and then enriching, centrifuging, ultrafiltration and concentrating, The hair follicle stem cell active factor concentrate is obtained; S3, mixing and freeze-drying: after mixing the hair follicle stem cell active factor concentrate and the auxiliary solution in a mixing box, a mixed solution is obtained; after the mixed solution is lyophilized for a second time, a treatment for hair loss is obtained. Freeze-dried powder of hair follicle stem cell active factor. Moreover, the invention replaces the hair follicle stem cell factor solution with the hair follicle stem cell active factor freeze-dried powder, so as to solve the problem that the hair follicle stem cell culture solution in the liquid state has a short storage time in the greenhouse and is not conducive to transportation.

The invention discloses green healthcare fruit wine and a preparation method thereof. The green healthcare fruit wine is prepared from the following raw materials in parts by weight: 10 to 20 parts ofapple juice, 8 to 12 parts of litchi juice, 3 to 5 parts of sweet-scented osmanthus flower, 6 to 8 parts of nutritional addition solution, 60 to 80 parts of fermentation matrix, 2 to 4 parts of yeast, 5 to 7 parts of traditional Chinese medicine additive, 0.1 to 0.3 part of vitamin additive, 0.7 to 1.3 parts of sorbitol, and 30 to 40 parts of distilled water. The fruit wine is strong in fruit fragrance, soft, tasty, refreshing and mellow in taste and has effects for nourishing the lung, promoting the secretion of saliva or body fluid and nourishing the mind and body and has higher nutritionalvalue; and the preparation method provided by the invention is nontoxic and harmless in raw materials, convenient for obtaining the raw materials, low in raw material cost, simple in process, higherin practical value and good in application prospect, and the prepared green healthcare fruit wine is suitable for people to drink for a long time.

The invention discloses a tea seed oil heat-clearing lung-moistening health-care beverage and a preparation method thereof. The tea seed oil heat-clearing lung-moistening health-care beverage is characterized by comprising the following raw materials in parts by weight: 30-40 parts of high-quality tea seed oil, 20-30 parts of a bacteriostatic plant additive, 10-20 parts of a fresh flower extract,5-7 parts of a nutritional additive, 0.7-0.9 part of a quality guarantee additive, 0.3-0.5 part of heme iron, 10-14 parts of tea leaves, 5-15 parts of a taste enhancer and 150-190 parts of distilled water. The tea seed oil heat-clearing lung-moistening health-care beverage has the advantages of complementary nutrition, coordinated flavor, rich nutrition, health care function and the like, and theadded components have functions of clearing away heat and toxic materials, moistening the intestines and stomach, and regulating QI and moistening the lung, and have good color uniformity; and meanwhile, the preparation method keeps the nutritional ingredients of the raw materials as much as possible, the raw materials are nontoxic and harmless, the materials are convenient to obtain, the cost islow, the process is simple, and the tea seed oil heat-clearing lung-moistening health-care beverage has high practical value and good application prospect.

The invention relates to an areno [c] carbazoles derivative and a synthetic method thereof. According to the technical scheme, environmentally friendly and low-price ammonium iodide is used as a catalyst, 2,3-dichloro-5,6-dicyano benzoquinone as an oxidizing agent, a mixture of one or more of hexamethylene, toluene, dimethylbenzene, trimethylbenzene, benzotrifluoride, ethylbenzene, chlorobenzene,o-dichlorohenzene, anisole, decahydronaphthalene and 1,4-dioxane is used as an organic solvent, and simple raw materials including an indoles derivative, a cyclohexanones derivative and olefins derivative are synthesized into areno [c] carbazole and a derivative thereof in a pot. The shortcomings that by an existing synthetic method, when a metal catalyst or a metal oxidizing agent requires or a starting raw material with relatively high activity requires, synthesis steps are complicated, reaction conditions are severe and the like are overcome. The synthetic method is suitable for preparing the areno [c] carbazoles derivative with certain photoelectric property, bioactivity and drug activity.

The invention provides a crosslinked pectin fiber and a preparation method thereof, and belongs to the field of macromolecular fiber. The method comprises the steps: firstly, mixing a pectin aqueous solution and a polyoxyethylene aqueous solution, then adding a surfactant and a cosolvent, to obtain a mixed solution, and spinning the mixed solution, to obtain an electrospinned nanofiber; and then crosslinking the obtained electrospinned nanofiber, to obtain a crosslinked nanofiber; and finally, washing the obtained crosslinked nanofiber, and thus obtaining the crosslinked pectin fiber. The invention also provides the crosslinked pectin fiber obtained by the preparation method. The pectin nanofiber contains no other chemical components and enables a stable nanofiber structure to be kept under a condition of water phase, so that the crosslinked pectin fiber has better biocompatibility and water resistance, has relatively high mechanical strength, and can meet a lot of biomedical requirements.

The preparation method comprises the following steps: step 1, preparing a certain amount of wormwood juice, mosquito-repellent vanilla juice, platycladus orientalis juice, rosemary juice, artemisia capillaris juice, mint juice and eupatorium fortunei juice for later use; according to the invention, the natural plant extract is an important secondary substance of plants, and has the characteristics of various biological activities, natural inoculation action mechanisms, pure nature, no pollution and the like. Juice extracted from the raw materials of wormwood, mosquito-repellent vanilla, platycladus orientalis, rosemary, artemisia capillaris, mint and eupatorium has various natural antibacterial, anti-inflammatory, itching-relieving and detumescence components, and various volatile oil is natural raw materials, so that the volatilized smell not only can naturally repel mosquitoes, but also cannot enable the mosquitoes to generate resistance, and the mosquito-repellent effect is lasting and effective.

The invention belongs to the field of chemical synthesis, and in particular relates to a water-phase one-pot synthesis method of 3-hydroxyflavone and derivatives thereof. In the present invention, 2-hydroxyacetophenone and its derivatives and benzaldehyde and its derivatives are used as reaction substrates, or 2-hydroxychalcone and its derivatives are used as reaction substrates, and water or ethanol aqueous solution is used as solvent. Under aerobic conditions, 20-100°C, react to obtain 3-hydroxyflavone and its derivatives. The present invention provides a brand-new reaction mechanism, and develops a new method for synthesizing 3-hydroxyflavones with high efficiency, convenience and broad substrate adaptability; the present invention also utilizes the new method to synthesize a brand-new 3-hydroxyflavone Derivatives have important application value in the medical and health field.