89 results about "Butyl hydroxybenzoate" patented technology

Microbial growth on the surface of a valve of a voice prosthesis and optionally the cartridge or ring supporting the valve, is inhibited by providing antimicrobial activity at a level sufficient to retard growth of a microbial film by dispersing an inorganic antimicrobial agent such as silver oxide or an organic antimicrobial agent such as triclosan or butyl paraben dispersed in a medical grade silicone elastomer. The valve, ring or cartridge is in contact with body fluids containing microorganisms and nutrients therefor. The antimicrobial surface can interfere with or inhibit the growth of a biofilm, bacterial layer or a yeast layer. The body of the prosthesis may also contain an antimicrobial surface as long as it is non-toxic to the tissue it contacts.

The invention discloses a compound preservative and an application thereof and aims to provide one compound preservative which is simple in preparation method and is good in antiseptic and antibacterial properties. The preservative disclosed by the invention is used as an additive of a skin care product. The technical key points are as follows: the preservative is composed of a solute and phenoxyethanol in a mass ratio of 1 to 1, wherein the solute is composed of the following components in mass percentage: 1%-40% of methyl p-hydroxybenzoate, 1%-40% of ethyl p-hydroxybenzoate, 1%-20% of propyl p-hydroxybenzoate and 1%-15% of butyl p-hydroxybenzoate; the sum of all the components is 100. The invention provides the application of the compound preservative as the additive of the skin care product, belonging to the technical field of household chemicals.

The invention discloses a discoloring solid rubber stick and a preparation method thereof. The discoloring solid rubber stick is prepared from the following raw materials in parts by weight: 55.0-85.0 parts of water, 15.0-25.0 parts of polyvinylpyrrolidone, 5.0-10.0 parts of styrene-acrylic emulsion, 10.0-15.0 parts of acrylic emulsion, 5.0-10.0 parts of dextrin, 5.0-15.0 parts of propylene glycol or glycerin, 5.0-15.0 parts of stearic acid, 0.5-3.0 parts of sodium hydroxide, 1.0-5.0 parts of light changing pigment, 10.0-15.0 parts of calcium carbonate or kaolinite and 0.2-3.0 parts of butyl p-hydroxybenzoate. The discoloring solid rubber stick disclosed by the invention has the characteristics of high bonding strength, high bonding speed, good temperature resistance, long storage life, beautiful color, unique style and the like, can be cleaned with water and stored for long time, and is safe and environment-friendly, easy to use and wide in range of application.

The invention discloses sunscreen cream which is composed of three components of A, B and C, which is counted by weight percent, wherein, the composition of the three components of A, B and C is as follows: component A contains 45-60 parts of deionized water, 1-6 parts of stearic acid, 1-4 parts of tiethanolamine, 1-10 parts of polyoxyethylene hexadeca alcohol ether, and 1-5 parts of glycerine; component B contains 5-15 parts of myristic acid isopropyl alcohol, 1-10 parts of glyceryl monostearate, 1-10 parts of lanoline, 0.1-0.5 parts of methyl hydroxybenzene formic ether, 1-5 parts of cetyl alcohol, 0.2-0.6 parts of butylphydroxybenzoate, 1-10 parts of salicylic acid menthyl acetate, and 1-6 parts of span -60; and component C contains 0.2-0.6 parts of essence and 0.2-0.6 parts of color element. The operation of the invention is convenient, the invention has intercluding effect of good ultraviolet ray UVA, and can effectively prevent the generation of melanin, to ensure that the derma is free from black and injury, and the invention can ensure that the derma keeps vital and lenitive.

The invention discloses heat-resisting high-toughness polystyrene resin foaming plastic. The heat-resisting high-toughness polystyrene resin foaming plastic is prepared from, by weight, 40-55 parts of polystyrene resin, 2-3.5 parts of potassium titanate fibers, 11-16 parts of coconut fiber, 2-6 parts of polytetrafluoroethylene, 1-1.5 parts of 3,5-tert-butyl-4-hydroxy phenyl, 15-20 parts of talcum powder, 6-11 parts of silicon carbide powder, 4-13 parts of kaolin, 1.2-1.8 parts of bis(2-ethylhexyl) phthalate, 1.1-1.6 parts of zinc stearate, 1-1.5 parts of butyl p-hydroxybenzoate and 2-5 parts of foaming agents. The heat-resisting high-toughness polystyrene resin foaming plastic has the good heat-insulating property and the good strength and toughness, and the impact-resisting property of the plastic is improved.

The invention discloses fresh fruit mint mouthwash, and belongs to the technical field of personal care products. The fresh fruit mint mouthwash comprises the following components in parts by weight: 95 to 98 parts of water, 1 to 2.5 parts of glycerin, 0.5 to 1.2 parts of PEG-40 hydrogenated castor oil, 3 to 5 parts of essence, 0.01 to 0.05 part of saccharin sodium, 0.01 to 0.02 part of menthol, 0.01 to 0.3 part of chlorhexidine digluconate, 0.1 to 0.3 part of cetyl pyridinium chloride, 0.05 to 0.3 part of methyl benzoate, 0.05 to 0.3 part of ethyl hydroxybenzoate, 0.05 to 0.3 part of nipasol, 0.01 to 0.3 part of butoben, 0 to 0.005 part of eugenol and 0 to 0.005 part of limonene. According to the mouthwash, bad breath can be effectively removed, fresh breath can be kept persistent, and antibacterial effects and anti-caries effects can be achieved.

A hydroxypropyl-beta-cyclodextrin supermolecule clathrate (inclusion) compound of butyl p-hydroxybenzoate, which is a mildew-resistant and anti-bacterial medicine, and a preparing method and a using method thereof are disclosed. The clathrate (inclusion) compound comprises the butyl p-hydroxybenzoate and hydroxypropyl-beta-cyclodextrin in a weight ratio not less than 1:7.5. The butyl p-hydroxybenzoate obtains good water solubility and the water solubility of the butyl p-hydroxybenzoate turns from insolubility to easy solubility, and therefore the problem that an aqueous butyl p-hydroxybenzoate solution is not liable to apply or operate is overcome, the butyl p-hydroxybenzoate can be applied in a circumstance of high concentrations, and the butyl p-hydroxybenzoate obtains good usability and can be directly added into an aqueous solution or can be directly dissolved with water together with other components. By protection of the hydroxypropyl-beta-cyclodextrin, possible chemical compatibility and degradation invalidation problems with other components in the solution are overcome, so that good stability is achieved. The supermolecule clathrate (inclusion) compound of the hydroxypropyl-beta-cyclodextrin and the butyl p-hydroxybenzoate maintains mildew-resistant and anti-bacterial functions and maintains the range unchanged.

The invention provides a detection method for measuring eight preservatives in reconstituted tobaccos simultaneously. The method comprises the steps that a methanol-formic acid-water solution is used as extraction liquid, a reconstituted tobacco sample is subjected to ultrasonic extraction, the extracting solution is filtered by an organic filter film, a high performance liquid chromatography-tandem mass spectrometry combined method is adopted for measuring eight preservatives comprising dehydroacetic acid, sorbic acid, benzoic acid, salicylic acid, methyl 4-hydroxybenzoate, ethyl p-hydroxybenzoate, propyl p-hydroxybenzoate and butyl p-hydroxybenzoate. An isotope dilution internal standard method is adopted for quantification to avoid quantitative separation and purification difficulty of a complex mixture system; due to the fact that the methanol-formic acid-water solution is used as the extraction liquid, extraction efficiency is ensured, the amount of organic impurities in the sample entering a chromatographic column can be reduced, and the chromatographic column is effectively protected. The method is high in analysis speed, good in repeatability and recovery rate and applicable to analysis of large-batch products in industry.

The invention discloses application of a natural antibacterial peptide As-CATH4 in food preservation and fresh-keeping. The natural antibacterial peptide As-CATH4 in the present invention has a broad-spectrum and high-efficiency antibacterial effect on common food spoilage bacteria, has a rapid sterilization effect, and has a good synergistic effect with a traditional preservative butyl p-hydroxybenzoate. The combination of As-CATH4 and butyl p-hydroxybenzoate significantly inhibits the growth of spoilage bacteria, increases sensory evaluation score, and prolongs food storage time. In the storage experiment of salmon meat, cooked meat sauce and freshly squeezed fruit juice, As-CATH4 significantly inhibits the growth of spoilage bacteria, increases sensory evaluation score, and prolongs food storage time. In the storage experiment of orange juice, the combination of As-CATH4 and butyl p-hydroxybenzoate significantly inhibits the growth of spoilage bacteria, prolongs food storage time, and shows a good synergistic effect. In addition, As-CATH4 can be completely degraded by trypsin and has no toxic side effects on human body. As a new type of food preservative, As-CATH4 has wide application prospects.

The invention discloses a composition for treating oral mucositis. The composition is prepared from ropivacaine mesylate and an aluminum hydroxide and magnesium hydroxide suspension in a dose ratio of 0.5-5mg to 1ml. The invention further discloses a method for preparing the composition for treating oral mucositis. The method comprises the following steps: 1, preparing the suspension from hydroxyethyl cellulose, hydroxy propyl cellulose, simethicone, aluminum hydroxide and magnesium hydroxide; 2, adding sorbitol, mannitol and butyl p-hydroxybenzoate to regulate the pH value to obtain the aluminum hydroxide and magnesium hydroxide suspension; and 3, adding ropivacaine mesylate into the aluminum hydroxide and magnesium hydroxide suspension, and uniformly stirring to obtain the suspension for treating oral mucositis. The invention further discloses an application package for the composition for treating oral mucositis. The composition for treating oral mucositis has the advantages of relieving pain and diminishing inflammation, repairing the mucosa ulcer face and the like, and is convenient to use.

The invention relates to body lotion for deeply moisturizing skin, each part of which comprises the following components: 2.0-2.2% of stearic acid, 0.6-0.8% of hexadecanol, 0.4-0.6% of stearyl alcohol, 0.9-1.1% of Tween-60, 1.2-1.4% of Span-60, 2.0-2.4% of squalane, 8-10% of isopropyl palmitate, 0.10-0.12% of butyl-p-hydroxybenzoate, 0.20-0.24% of methyl-p-hydroxybenzoate, 0.10-0.11% of polyacrylic acid, 5-6% of propanediol, 2.0-2.5% of glycerin, 1.0-1.2% of triethanolamine, 0.1% of essence and the balance deionized water. The prepared lotion is uniformly applied to the skin by way of gentle circling and the skin is patted until the lotion is fully absorbed. The lotion can effectively replenish the water needed by the skin, replenish water deeply and simultaneously supplement the oily compositions needed for moisturizing the body. Matching of water and oil can ensure the skin to have optimal states of elasticity and moisturizing.

The invention relates to the field of a film, and specifically speaking relates to a composition used for preparing an anti-corrosion heat-insulation automobile film and a preparation method thereof.An anti-corrosive coating employs butyl 4-hydroxybenzoate as a main raw material to increase the anticorrosion performance of the automobile film, tert-butyldimethylsilyl chloride is used for protecting a hydroxyl group in butyl 4-hydroxybenzoate, stability of butyl 4-hydroxybenzoate is effectively increased, acid-resistant performance is increased, a preferably selected anti-oxidant is combined with poly-L-monosodium glutamate for usage, and stability effect can be achieved. through preferably selecting the usage materials of a thermal-insulation layer and a wearing layer, and the heat insulation and antifriction effects are better than that of the prior art. An improved copolymer and carboxyl-terminated hyperbranched polyester are employed, so that long-term storage is achieved, and theperformance cannot be changed.

The invention discloses a preparation method of butyl p-hydroxybenzoate, comprising the following steps of: firstly cleaning a 4A zeolite by distilled water, and controlling activation temperature; activating for a period of time, cooling, and then weighing a certain amount of the 4A zeolite; soaking in a toluenesulfonic acid solution; removing a water solution, and then drying to obtain a needed catalyst; adding p-hydroxybenzoic acid, butanol, toluene, benzyltriethylammonium chloride and the catalyst to a flask together, reacting in a reflux state, and also separating water; after the reaction is finished, filtering to remove the catalyst, and steaming unreacted and toluene; adding residues to cold water for intensely stirring so as to separate out white crystals; then neutralizing unreacted acid by a sodium carbonate solution till the sodium carbonate solution becomes alkalescent; filtering, and drying to obtain a product of the butyl p-hydroxybenzoate. The invention has low cost, easy storage, no side reaction in the production process, and corrosive damage on equipment.

The invention discloses an application of butyl p-hydroxybenzoate in preparing candida albicans resistant drugs. According to the application, the inventor takes candida albicans as the test object toscreen effective and low-toxicity chemical compound not easy to generate drug resistance, and finds that butyl p-hydroxybenzoate have good suppression effect to adhesion and pathogenicity of candidaalbicans. Besides, the chemical compound has low toxicity which cannot affect growth of human cells. Meanwhile, no influence is caused to normal growth of candida albicans, that is to say, the chemical compound suppresses adhesion, hypha formation, biofilm formation and pathogenicity of candida albicans rather than kills candida albicans mainly, and accordingly is not easy to generate drug resistance. The development of the novel antifungal drug, especially the development of the candida albicans resistant drugs has good application prospect.

The invention provides a preparation method of a concentrated solution for temsirolimus injection. The concentrated solution is mainly prepared from active component, benzyl alcohol, butyl hydroxybenzoate, organic acid or inorganic acid, pH regulator and absolute ethyl alcohol. The prepared preparation has few related substances, is stable in long-term storage process, and meanwhile solves the problem that due to the introduction of water, temsirolimus isomers and related substances are increased.

The invention discloses environment-friendly type cooling fluid. The environment-friendly type cooling fluid is prepared from the following components of propylene glycol, maleic anhydride, 4-hydroxybenzoate, octanedioic acid, diethanolamine, amber acid, nanometer pottery clay, silicate ester, polyethylene glycol, a corrosion inhibitor, an antifoaming agent, a dispersing agent and water. The cooling fluid disclosed by the invention is environment-friendly and good in cooling properties; through synergistic reaction of the components, the organizational structure properties of the cooling fluid are improved, the component composition of the cooling fluid is improved, and the comprehensive properties in various aspects of the cooling fluid are improved; the cooling fluid disclosed by the invention has the efficacies of preventing freezing, preventing boiling, preventing corrosion and preventing scaling, and is high in heat transmission speed and good in cooling effects; damage to environment and human bodies is reduced; in the preservation period of the cooling fluid, gel cannot be produced, and the corrosion inhibitor cannot be separated, and the cooling fluid has long-term effects; the cooling fluid product is simple in making technology and process, little in use equipment, easy to operate, low in required energy consumption, low in production cost and easy in industrialized large-scale production, has very high popularization and application values, and has good city prospects.

The invention relates to wickerwork pigment paint. The wickerwork pigment paint is prepared from rosin, plant pigment, perfluorinated naphthylamine, polymethyl hydrogen siloxane, sodium carbonate, bis(triazinyl)aminostilbene, trihydroxy butyl benzoate, sodium benzoate, diacetyl tartaric acid ester of mono(di)glycerides, dioctyl sebacate and glycol dimethyl ether. According to the wickerwork pigment paint disclosed by the invention, by adoption of multiple oil paint additives, the volatility of oil paint can be reduced, and the harm of the oil paint to a human body is reduced. By means of the additives in the oil paint, degreasing and dyeing can be simultaneously performed, and operation steps of dyeing are reduced; in addition, the oil paint is easy to dry and good in toughness; the surface of a wickerwork product can be effectively protected.

The invention provides an environment-friendly recovered grease decolorizing agent and a preparation method thereof. The environment-friendly recovered grease decolorizing agent is prepared from the following ingredients: water washing acidification rice hull ash, non-water washing-acidification rice hull ash, carbonized soybean hull ash, chitosan, dodecyl dimethyl benzyl ammonium chloride, epigallocatechin gallate, dilauryl thiodipropionate, sorbic acid, butyl p-hydroxybenzoate, ethyl alcohol, hydrochloric acid and water. The preparation method is characterized in that firstly, the chitosan, the hydrochloric acid and the water are mixed, and the mixture is stirred by a magnetic stirrer to obtain a solution A; the sorbic acid, the butyl p-hydroxybenzoate and the ethyl alcohol are mixed and stirred to obtain a solution B; then, the rest ingredients, the solution A and the solution B are mixed, and are then stirred by the magnetic stirrer to be put into a drying box to be dried. The environment-friendly recovered grease decolorizing agent has the advantages that the decolorizing can be fast and effectively performed; meanwhile, partial metal ions are removed; the peroxide value is reduced; the recovered grease quality is improved; in addition, the preparation method is simple and is suitable for industrial production.

The invention relates to an active rutin whitening cream which comprises polyoxyethylene mono-stearate, glycol mono-stearate, stearic acid, docosyl alcohol, squalane, hexadecyl, cetyl isooctanoate, butyl p-hydroxybenzoate, methyl p-hydroxybenzoate, 1,3-butanediol, enoxolone disylvite, rutin, essence and purified water. The whitening cream is spread on the face after the face is cleaned. The invention can resist skin aging and relieve wrinkles and facial stains.

The invention discloses an amiotide eye drop containing a composite bacteriostatic agent. The composite bacteriostatic agent is phydroxybenzoate ester and phenethyl alcohol, wherein the concentration of the phydroxybenzoate ester is 0.1 to 0.4g/L; the concentration of the phenethyl alcohol is 4 to 5ml/L; and the phydroxybenzoate ester is one of or a mixture of more than two of methyl parahydroxybenzoate, ethyl p-hydroxybenzoate, propyl p-hydroxybenzoate and butyl p-hydroxybenzoate. Through the combined collaborative bacteriostatic action of the phydroxybenzoate ester and the phenethyl alcohol, the amiotide eye drop can improve the bacteriostatic activity, enhances the microbial contamination resistance, expands the antibacterial spectrum and has relatively high inhabitation effect on gram-negative bacterium, gram-positive bacterium and fungi. The potency assay of the bacteriostatic agent proves that the amiotide eye drop completely accords with the rule of a bacteriostatic agent efficacy test method guiding principle, which is the appendix of 'China Pharmacopeia 2000 (vol. II)', and the safety and the efficiency of the amiotide eye drop can satisfy clinical needs.

The present invention relates to the technical field of rubber chemicals, and particularly relates to a natural rubber latex preservative. The rubber latex preservative comprises the following raw materials in parts by weight: 0.2-0.5 part of sodium metabisulfite, 0.1-0.5 part of butyl p-hydroxybenzoate, 4-10 parts of sodium bicarbonate, 1-5 parts of sodium benzoate and 1-3 parts of citric acid. Object of the present invention is to provide a safe, environmentally-friendly, low-price, easy-to-use natural rubber latex preservative.

The invention discloses a vitamin E nourishing and skin-care lotion. The prescription of the skin-care lotion consists of the following raw materials in parts by weight: 5 parts of vitamin E, 1 part of hexadecanol, 1 part of octadecanol, 0.7 part of polyoxyethylene (20) ether, 0.9 part of stearic acid, 0.3 part of dimethyl siloxane, 0.2 part of monoglyceride, 0.1 part of propyl p-hydroxybenzoate, 0.05 part of butyl p-hydroxybenzoate, 4 parts of propylene glycol, 13 parts of polyacrylic resin, 0.2 part of methyl p-hydroxybenzoate, 0.2 part of imidazolidinyl urea, 0.05 part of disodium EDTA, 0.4 part of triethanolamine, a proper amount of essence and de-ionized water to 100 parts. The skin-care lotion provided by the invention, on the basis of a synergistic effect caused from the dosages and physicochemical properties of the various raw materials, can achieve effects of scavenging free radicals, lightening spots and whitening. The skin-care lotion provided by the invention, which is close to human skin in PH value, is non-irritant to the skin; and a user, applied with the trace-element skin cream, can feel obviously comfortable and soft, without the feeling of being greasy, and the skin-care lotion has obvious effects of nourishing and whitening, protecting skin and keeping beauty.