69results about How to "Suitable for industrial mass production applications" patented technology

The invention belongs to the field of fluorine chemical synthesis and particularly relates to a fluorination method for end groups of perfluoropolyether acid. The perfluoropolyether acid and a fluorinating agent are taken as raw materials for synthesis in a gas-liquid contact reaction tube with fluorine gas passivated filler as a filling agent, and the filler adopts one or a mixture of carbon steel, stainless steel 304 and stainless steel 316. The perfluoropolyether acid or a solution thereof sprays downwards from the top of the gas-liquid contact reaction tube, a fluorinating agent gas makes sufficient contact with perfluoropolyether continuously from bottom to top through filler gaps in the gas-liquid contact reaction tube, maximized gas-liquid contact is realized, so that the utilization of the fluorinating agent is realized to the greatest extent, and fluorination of the perfluoropolyether is sufficient and complete. Besides, the perfluoropolyether is subjected to continuous fluorination, the problem of kettle-by-kettle fluorination in the prior art is solved, and the operation procedure is simplified. Few by-products are produced during fluorination of the perfluoropolyether, the operation is simple, continuous production can be realized, reactions are safe and stable, and the method is suitable for industrial mass production and application.

The invention provides a synthesis method of mirabegron. The synthesis method comprises the following steps: (1) in a tetrahydrofuran solvent and a nitrogen atmosphere, reducing a compound I into a compound II by adopting a reducing agent; (2) in an alcohol solvent and a hydrogen environment, reducing the compound II into a compound III by adopting palladium-on-carbon catalytic hydrogenation; and (3) in a water solvent and under an acidic condition, mixing the compound III with 2-amino-4-thiazole acetic acid, and performing condensation reaction under the action of a condensing agent, to obtain mirabegron. The method has the advantages of being mild in reaction conditions, high in yield and low in cost, and the provided mirabegron is low in the content of impurities, therefore, the synthesis method is suitable for large-scale industrial production.

The invention belongs to the field of fluorine chemical synthesis and particularly relates to application of a gas-liquid contact reaction device to fluorination of perfluoropolyether acid. The gas-liquid contact reaction device comprises a gas inlet cylinder for containing fluorinating agent gas, a reaction tube filled with filler, a liquid cylinder, a product collecting cylinder and a tail gas treatment device, wherein a liquid outlet connected with the product collecting cylinder and a gas inlet connected with the gas inlet cylinder are formed in the bottom of the reaction tube, a spray head is arranged at the top end of the reaction tube and is connected with the liquid cylinder through a liquid pump, a gas outlet connected with the tail gas treatment device is formed in the top of the reaction tube, and heating strips are arranged on the outer wall of the reaction tube. The gas-liquid contact reaction device is capable of fluorinating the perfluoropolyether acid by fluorine gas effectively.

The invention discloses a cell surface exhibition PET decomposing enzyme reorganizable pichia pastoris and structure and application, comprising the structured steps of 1, chemo synthesizing the nucleotide sequence of ameliorated PET decomposing enzyme as shown in SEQ ID No. 1; cloning the nucleotide sequence of anchoring protein gene from the gene group of GS115 pichia pastoris; 2, utilizing the OverlapPCR to connect the nucleotide sequence of anchoring protein gene and the nucleotide sequence of ameliorated PET decomposing enzyme and obtaining an amalgamation sequence; 3, connecting the amalgamation sequence to an expression load of pichia pastoris, and obtaining a reorganizable expression load; 4, transferring the reorganizable expression load in a host pichia pastoris, and obtaining a reorganizable pichia pastoris of a cell surface exhibition PET decomposing enzyme. The reorganizable pichia pastoris can anchor the PET decomposing enzyme to the cell surface, the enzyme after Immobilization can be used for an entire cell catalyst, compared to the wild grow type, has high stability, is convenient to recover, easy to control and can be repeatedly utilized.

The invention provides a carbon aerogel. The carbon aerogel is of a three-dimensional network structure stacked by carbon particles; the surface of the carbon particle is of a micropore structure; thecarbon aerogel is a super-pure carbon aerogel without metal element impurities. The carbon aerogel has the advantages that a uniform mesopore structure is formed, the stereo feel of the three-dimensional network is strong, the space network structure is stacked by the carbon microspheres, the microspheres are tightly distributed and connected, and the whole structure is complete; the carbon aerogel has the mesopore structure stacked by the carbon microspheres, and the carbon microsphere self has a large amount of micropore structures, so as to enhance the specific surface area of the carbon aerogel, and the BET specific surface area can reach about 1300m<2>/g; the normal-pressure drying method is adopted, the solvent exchange is avoided, the inorganic metal alkaline catalyst is not used,and the super-pure carbon aerogel with good biocompatibility is obtained; the carbon aerogel can be widely applied to the fields of food-level medicine loading, catalyst loading, material adsorbents,energy storage materials and the like.

The invention discloses a preparation method for an electrode material of a super capacitor. The preparation method comprises the following steps of: preparing an aqueous solution of permanganate at the concentration of 0.02 to 0.20 mol/L, and adding polyethylene glycol with stirring to obtain a mixed solution, wherein the volume ratio of the polyethylene glycol to the aqueous solution of permanganate is 1:8 to 1:40; stirring the mixed solution, and filtering the mixed solution to obtain precipitates; and washing and drying the precipitates to obtain the electrode material of the super capacitor. The preparation method for the electrode material of the super capacitor has the characteristics of simple process, short flow, low dependence on equipment and suitability for large-scale production; and the prepared electrode material of the super capacitor has high performance.

The invention provides a membrane electrode and a preparation method thereof, a sensor by employing a membrane electrode, an electrochemical workstation and application thereof. The membrane electrodecomprises an electrode and a modified membrane on the surface of the electrode, the modified membrane is a mixture of chitosan and alizarin red S; the modified membrane of the chitosan and the alizarin red S is deposited at the surface of the electrode to allow the obtained membrane electrode to have high sensitivity, high sensing effect and have responsiveness to the current change; the preparation method of the membrane electrode is simple, easy to obtain raw materials, low in cost and easy to implement and can be suitable for industrial large-scale production application; and the sensor comprising the membrane electrode is high in detection sensitivity and good in accuracy; the electrochemical workstation comprising the sensor can achieve the qualitative and quantitative detection of aluminum ions, and is high in sensitivity, small in relative standard deviation and high in accuracy.

The invention provides a synthesis method of agmatine sulfate. The method comprises the steps of carrying out addition reaction by taking 1,4-butanediamine as a raw material and a cyanamide water solution as a guanidination reagent to obtain agmatine, and forming salt with sulfuric acid to obtain agmatine sulfate. The synthesis method disclosed by the invention, by taking cyanamide water solution as the guanidination reagent, is moderate in reaction condition, easy to control, light in pollution, favorable for environmental protection, low in cost, and suitable for industrial production and application on a large scale.

The invention provides a coating, a preparation method and an application thereof. The coating comprises the following components in parts by weight: 400-500 parts of odorless emulsion, 600-700 partsof colorful sand, 10-30 parts of coalescing agent, 0.5-4 parts of organic silicon pH regulator, 8-15 parts of cellulose, 0.5-2 parts of plant de-foaming agent and 450-500 parts of RO purified water. The prepared coating has excellent water resistance, appearance and processability; the coating has little odor and is low in content of VOC, SVOC, free formaldehyde and heavy metal; the preparation method is simple; the raw materials are easily acquired and are low in cost; the coating can be used for decorating household or commercial inner walls.

The invention discloses a method for producing iron-containing slag and high zinc materials through cloth bag dedusting ash. The method comprises the steps that a mixed material containing 80%-95% ofthe cloth bag dedusting ash in weight percentage is burnt, restored, oxidized and collected to obtain the high zinc materials and the iron-containing slag. By means of the method for producing the iron-containing slag and the high zinc materials through the cloth bag dedusting ash, the cloth bag dedusting ash is efficiently recovered and processed, the process technological flow is simple, valuable elements in the cloth bag dedusting ash are extracted, the added value of the cloth bag dedusting ash is increased, the method has important practical significance in cleaning production, energy conservation and emission reduction in the iron and steel industry, and the method is suitable for industrialization large-scale production and application.

The invention discloses a ferro-nickel hydroxide/ferro-nickel alloy loaded wood-based electrocatalyst, which comprises a charcoal skeleton with a three-dimensional porous structure and an active substance loaded on the charcoal skeleton, the active substance comprises a ferro-nickel hydroxide/ferro-nickel alloy heterojunction taking ferro-nickel alloy as a bottom layer and ferro-nickel hydroxide as a surface layer. The invention also provides a preparation method of the ferro-nickel hydroxide/ferro-nickel alloy loaded wood-based electrocatalyst and a water electrolysis hydrogen production catalyst. The ferro-nickel hydroxide/ferro-nickel alloy loaded wood-based electrocatalyst has the advantages of high catalytic efficiency, good stability, simple process and the like.

The invention provides a coating method for traditional Chinese medicine micro-pellets; pharmaceutically acceptable excipients are used for wrapping the surface of micro-pellets containing a traditional Chinese medicine extract with a powder layer, and then coating is performed with a fluidized bed coating technology. The coating method of the traditional Chinese medicine micro-pellets can be usedfor coating various traditional Chinese medicine blank micro-pellets, especially for micro-pellets containing traditional Chinese medicine extracts with large viscosity, can obviously improve the problems of stickiness, bed collapse, chromatic aberration and color spots in the process of fluidized bed coating of traditional Chinese herbal medicine extract micro-pellets, has the advantages of highpelleting rate, good formability, simple operation, low production cost and high efficiency, and is suitable for industrial mass production and application.

The present invention provides a multifunctional slow-release organic bacterial fertilizer. The organic bacterial fertilizer comprises organic matters, bacteria beneficial to plant growth, dopamine ora salt thereof, a high polymer molecule, sodium alginate and Ca<2+>. The dopamine is attached to the surfaces of the organic matters and beneficial bacteria; then the surface of the dopamine is covered with the high polymer molecule; finally, the surface of the high polymer molecule is coated with the sodium alginate and Ca<2+>; and thus the organic bacterial fertilizer capable of maintaining fertilizer with water of soil and slowly releasing live bacteria to a certain extent is prepared. The slow-release organic bacterial fertilizer can effectively maintain the fertilizer with the water of the soil and slowly release the live bacteria, thereby improving the utilization efficiencies of the fertilizer with the water and the living bacteria, improving disease resistance and stress resistance of crops, improving the soil fertility condition sustainably, and realizing efficient reuse of bio-organic waste materials. The provided slow-release organic bacterial fertilizer is simple and environmentally-protective in the preparation technology, free of organic solvents and suitable for industrial mass production applications.

The invention discloses a dichloromethane catalyst and a preparation method thereof. The dichloromethane catalyst comprises an alumina coating and a porous substrate; the surface of the porous substrate is coated with the alumina coating; a composite oxide precursor salt solution is impregnated on the porous substrate coated with the alumina coating, and then roasted to form the dichloromethane catalyst; the catalyst is prepared under normal pressure conditions; the solidly bonded alumina coating is prepared from alumina sol; composite oxide with catalytic activity can be formed through impregnating and then roasting the composite oxide precursor salt solution. The preparation method of a solution is simple, only needs the processes of impregnation and roasting, and is suitable for industrial large-scale production and application; the composite oxide formed after roasting of the selected specific composite oxide precursor salt solution has excellent catalytic activity on dichloromethane, and the catalytic conversion rate at 380 DEG C can reach 95% or above.

The invention discloses a synthesis method of 8-tert-butyl-2-chloromethyl-1, 4-dioxaspiro [4, 5] decane, and the method comprises the following steps: dissolving p-tert-butyl cyclohexanone and epoxy chloropropane in an aprotic solvent, and performing reacting under the catalytic action of Lewis acid to obtain the 8-tert-butyl-2-chloromethyl-1, 4-dioxaspiro [4, 5] decane. According to the method, epoxy chloropropane with lower price is used for replacing 3-chloro-glycerol in a conventional route, so the production cost of the product is reduced; the method has the advantages of mild reaction conditions, high reaction selectivity and few side reaction impurities, and the product can reach high purity and yield, so the method is suitable for large-scale industrial production and application.