70 results about "Ortho-mercaptobenzoic acid" patented technology

The invention relates to an SERS (Surface Enhanced Raman Spectroscopy) method for detecting alpha fetal protein based on a probe-marked immunogold and magnetic composite material, and belongs to the technical field of protein analysis detection. The method comprises the following steps: combining P-thiosalicylic acid (MBA)-molecule-modified gold nanoparticle particles with an alpha fetal protein antibody, preparing a surface-functionalized Fe3O4@SiO2 magnetic composite material, absorbing the alpha fetal protein in serum onto the functionalized Fe3O4@SiO2 magnetic composite material; performing an immune reaction on an immunogold probe and the Fe3O4@SiO2 magnetic composite material modified with an alpha fetal protein antigen; performing Raman spectrum detection. The concentration of the alpha fetal protein can be detected by substituting the Raman strength value of an obtained Raman spectrum characteristic peak of protein to be detected into a working curve of Raman strength value and alpha fetal protein antigen concentration. The method has the advantages of ultrasensitiveness, high selectivity, mild detection conditions and the like, and has extremely important meanings in clinical analysis and diagnosis.

The invention provides an oxytetracycline SERS detection method based on nanomaterial self-assembly. The oxytetracycline SERS detection method is used for detecting content of oxytetracycline (OTC) in aquatic products such as fish meal. According to the OTC SERS detection method, gold nanoparticles (80 nm particle size) are connected with gold nanoparticles (15 nm particle size) through a base sequence containing OTC aptamers, and 4-mercaptobenzoic acid is incubated on the surfaces of the gold nanoparticles, thereby generating Raman signals. When the OTC is in contact with a detection system, the OTC aptamers are in specific binding with the OTC, thus the distance between the 80nm gold nanoparticles and the 15nm gold nanoparticles is reduced, the hotspot is enhanced, and the Raman signals are enhanced, thereby achieving the detection purpose. The detection system can detect the oxytetracycline quantitatively, the linearity range is from 0.046 to 460 fg / mL, and the detection limit is 0.004 fg / mL. The oxytetracycline SERS detection method used for oxytetracycline detection has the advantages of being high in sensitivity and being fast and convenient, can be applied to detection of samples such as fish meal, and is accurate and reliable in result.

The invention relates to a surface-enhanced Raman scattering aptamer sensor for detecting polychlorinated biphenyls and application. Gold-silver core-shell nanoparticles are used as a Raman substrate;4-thiosalicylic acid as a Raman signal molecule is modified on the surface of the gold-silver core-shell nanoparticles; a PCB72 aptamer is used as a pollutant identification element for constructingto obtain the sensor. Compared with the prior art, the surface-enhanced Raman scattering aptamer sensor disclosed by the invention has the advantages that by adopting an advanced surface-enhanced Raman technology, the detection sensitivity of the sensor to PCB72 is greatly improved, the linear detection range of the sensor is 1pg / mL-1000pg / mL and the detection limit can reach 0.3pg / mL; meanwhile,by adopting the aptamer, specific recognition of the PCB72 is realized, and the detection selectivity of the sensor to the PCB72 is greatly improved. The sensor disclosed by the invention can be usedfor detection analysis of an actual water sample; compared with other analysis methods, an analysis method disclosed by the invention has the advantages that a sample does not need complex pretreatment; simplicity, quickness and ultrahigh sensitivity are realized.

The invention relates to a dendritic polymer and particularly relates to a dendritic polymer with a high refractive index and a preparation method thereof. The dendritic polymer with the high refractive index is prepared by reaction on a dendritic polymer and a benzene ring or sulfydryl-containing organic compound under the action of a catalyst and a high-temperature-resistant oxidant, wherein the dendritic polymer is one or more of PAMAM-G1, PAMAM-G2 or PAMAM-G3; the benzene ring-containing organic compound is one or two of benzoic acid or hydroxyl salicylic acid and the sulfydryl-containing compound is one or more of thiosalicylic acid, sulfydryl sulfonic acid or sulfydryl phenylboronic acid. The dendritic polymer with the high refractive index as an additive is added into well-illuminated epoxy resin and an organic silicon material, so that the refractivity can be remarkably improved. The preparation method provided by the invention is simple in process and easy to realize.

Surface enhanced Raman scattering (SERS) spectra of 4-mercaptobenzoic acid (4-MBA) self-assembled monolayers (SAMs) on gold substrates is presented for SAMs onto which gold nanoparticles of various shapes have been electrostatically immobilized. SERS spectra of 4-MBA SAMs are enhanced in the presence of immobilized gold nanocrystals by a factor of 107-109 relative to 4-MBA in solution. Large enhancement factors are a likely result of plasmon coupling between the nanoparticles (localized surface plasmon) and the smooth gold substrate (surface plasmon polariton), creating large localized electromagnetic fields at their interface, where 4-MBA molecules reside in this sandwich architecture. Moreover, enhancement factors depend on nanoparticle shape, and vary by a factor of 102.

The invention discloses a thioxanthone photoinitiator containing cyclic acetal shown as below and a preparation method thereof. The 1,3-benzodioxolane or 1,3-benzodioxane and derivative thereof and 2-thiosalicylic acid are used as raw materials and concentrated sulphuric acid is used as solvent to react at 0-70 DEG C for 1-24 hours and prepare the thioxanthone containing cyclic acetal. As cyclic acetal group is introduced in thioxanthone and cyclic acetal can be used as the co-initiator of thioxanthone, the compound of the invention can be directly used as photoinitiator to replace the thioxanthone / amine initiation system and reduce the yellowing and toxicity caused by amine co-initiator and have wide application prospect in the photocuring industrial field.

The invention discloses an SARS-CoV-2 ultra-sensitive biochip based on surface enhanced Raman scattering and a preparation method thereof, and belongs to the technical field of functional materials and biosensing detection. The preparation method comprises the following steps: assembling gold nanoparticles by taking a silicon wafer as a substrate, and modifying a novel coronavirus spike protein antibody (SARS-CoV-2spike antibody) and bovine serum albumin to obtain an SERS immune substrate; sequentially modifying the surface of Ag NPs with a Raman molecule p-mercaptobenzoic acid and an SARS-CoV-2spike antibody so as to prepare an SERS immune probe; then, using the SERS immune substrate for adsorbing novel coronavirus spike protein antigens (SAR-CoV-2spike antigen protein) with different concentrations and an SERS immune probe so that the SAR-CoV-2 ultra-sensitive biochip based on surface enhanced Raman scattering, which is of a sandwich immune sandwich structure, is obtained. According to the invention, the problems of low sensitivity and poor uniformity of the enhanced substrate prepared by an electrostatic adsorption method are solved, and the purpose of further improving the SERS detection sensitivity is achieved.

The invention relates to the technical field of surface enhanced Raman spectra and particularly relates to a surface enhanced Raman spectrum substrate for specifically detecting Cu2+, a preparation method thereof and application thereof. The preparation method comprises a step of adding NaBH4 into an AgNO3 solution to obtain a faint yellow solution under magnetic stirring, continuously stirring for 5 minutes, and adjusting the pH value of the solution to obtain an AgNPs solution, and a step of adding the obtained AgNPs solution into a 4-mercaptobenzoic acid solution, stirring, removing ice-water bath after reaction is finished, and restoring to room temperature to obtain a target product. A 4-mercaptobenzoic acid modified silver nanoparticle substrate material designed and synthesized in the invention has the advantages of good stability and high sensitivity, and the problem of poor stability of a metal nano-material is solved to a certain extent.

The invention discloses water-holding controlled-release biological compound fertilizer. The water-holding controlled-release biological compound fertilizer comprises, by weight, 20-35 parts of biomass charcoal, 0.06-0.08 part of sodium dodecyl sulfate, 0.02-0.05 part of polyvinylpyrrolidone, 10-18 parts of humic acid powder, 4-9 parts of medical stone powder, 8-15 parts of urea, 0.05-0.2 part of2-mercaptobenzoic acid, 6-13 parts of modified starch adhesives, 12-22 parts of acrylic acid, 0.1-0.3 part of benzoin dimethyl ether, 1-3 parts of ammonium persulfate, 7-16 parts of fermented organicfertilizer and 1-5 parts of microbial powder. The invention also provides a preparation method of the water-holding controlled-release biological compound fertilizer. The biological compound fertilizer has the advantages that the biological compound fertilizer has excellent water absorption and retention effect, multiple controlled release of the fertilizer effect can be realized, nutrients suitable for different nutrition requirements of different growth stages of the crops can be provided, the fertilizer utilization rate can be increased, sufficient supply of the nutrients and water for thewhole growth period can be guaranteed, and the yield is obviously increased.

The invention relates to a multi-responsive smart hydrogel for colon targeting and a preparation method thereof. An effective component of the hydrogel is a disulfide bond cross-linked carboxymethyl chitosan derivant. The preparation method of the multi-responsive smart hydrogel for colon targeting comprises the following steps of performing a reaction on a raw material carboxymethyl chitosan andmercaptobenzoic acid activated by EDC so as to prepare thiolated carboxymethyl chitosan, and then oxidizing thiol of the water solution of thiolated carboxymethyl chitosan by using air at room temperature and cross linking to form the multi-responsive smart hydrogel. The method has mild reaction conditions, no cross-linking agent was needed, and the prepared smart hydrogel has unique pH sensitivity, enzyme sensitivity and reduction sensitivity and has a potential application value in the field of transfer of colon targeted drugs.

The invention provides a nano composite material and a preparation method thereof, and a mercury ion detection method. The preparation method of the nano composite material comprises the steps that ferric chloride and polyvinylpyrrolidone react with ethyl orthosilicate to obtain Fe@SiO2; then, the Fe@SiO2 reacts with 3-aminopropyl triethoxy silane to obtain Fe@SiO2-NH2; then the Fe@SiO2-NH2 reacts with 4-mercaptobenzoic acid, N-hydroxyl succinimide and 1-(3-dimethylamino propyl)-3-ethylcarbodiimide hydrochloride to obtain the nanocomposite material Fe@SiO2-SH. The prepared nanocomposite material is used for detecting mercury ion content. Firstly, mercury ion enrichment is performed, then an applied magnetic field is adopted to perform separation and elution, and the mercury ion content is calculated through detection of an atomic fluorescence photometer. The prepared nanocomposite material can perform rapid enrichment of mercury ions and is simple in operation, rapid in separation and capable of accurately detecting a trace amount of mercury ions by magnetic separation and elution, and the detection accuracy can reach the order of magnitude PPT.

The invention relates to a colorimetric and surface-enhanced Raman dual-sensing analysis method for copper ions. The method comprises the following steps: S1, preparing gold nanoparticles modified by4-mercaptopyridine; S2, preparing silver nanoparticles modified by 4-mercaptobenzoic acid; S3, mixing and incubating the silver nanoparticles modified by 4-mercaptobenzoic acid and the gold nanoparticles modified by 4-mercaptopyridine, and obtaining a GNPs-AgNPs compound; S4, dropwise adding a solution to be tested onto the surface of the GNPs-AgNPs compound; carrying out colorimetric qualitativeanalysis on the standard color, then carrying out qualitative analysis by adopting an ultraviolet-visible absorption spectrometer, simultaneously detecting a Raman signal by adopting a Raman spectrometer, and realizing qualitative and quantitative detection by virtue of spectrum contrast and signal intensity conversion. Compared with the prior art, the GNPs-AgNPs structure prepared by the invention is used for detecting Cu<2+>, and the GNPs-AgNPs structure is combined with Cu<2+> to form a sandwich-like structure, so that the detection is extremely sensitive, the sample consumption is low, andthe detection limit is lower than that of a single probe molecule.

The invention belongs to the technical field of biomedical materials, and relates to a porous nano-scale soft colloid and a method for transporting cells or tissue cultures by using the porous nano-scale soft colloid. Isopropylacrylamide is used as a main body of the porous nano-scale soft colloid, and after molecule grafting, polymerization with 2-mercaptobenzoic acid and lauryl sodium sulfate iscarried out; grafted molecules comprise acrylic acid, methacrylic acid, methylene succinic acid, hydroxysuccinic acid, hydroxyethyl methacrylate, dimethyl methacrylate amino ethyl ester or methoxypolyethylene glycol; the porous nano-scale soft colloid is mixed with cells or tissue cultures to be transported, heating and inoculating of an obtained mixture to a cell culture plate, a culture bottleor other containers is carried out for transportation, cooling and centrifuging are carried out after transportation, and harvesting of complete cells or tissue cultures is realized again. Effective physical support, fixation and physical protection are provided in the transportation process of cells or tissue cultures, damage of collision and shearing force in the transportation process to the cells or tissue cultures is reduced, and the requirement for long-distance transportation of the cells or tissue cultures is met.

The invention provides a method for modifying different mercaptan or thiophenol molecules on the surface of plasmon metal to regulate and control a hot carrier-driven photocatalytic reaction generatedby plasmon. In the method, mercaptan and thiophenol molecules can be chemically adsorbed on the surface of the surface plasmon metal, and the operation process is simple, convenient and rapid. Meanwhile, it has been proved that the method can regulate plasmon-driven oxidation reaction of p-aminothiophenol, reduction reaction of p-nitrothiophenol, silver corrosion reaction, decarboxylation reaction of p-mercaptobenzoic acid and the like.

The invention relates to a method for visually and rapidly detecting chromium ions by using a nanometer silver compound probe, and particularly relates to a method for visually detecting chromium ions in a water solution by using nanometer silver modified by 4-sulfydryl benzoic acid and 4-nitrobenzene mercaptan. The method is mainly characterized in that the 4-nitrobenzene mercaptan and 4-sulfydryl benzoic acid are commonly modified on the surface of the nanometer silver to form a composite nanometer silver probe with two functional groups of nitro and carboxyl. The nanometer silver probe with double functional groups can be combined with chromium ions through complexing action, so that the nanometer silver is polymerized and the color is changed. According to the color change degree of the solution, the presence / absence and content of chromium ions in the solution can be judged by naked eyes. The detection method is simple and easy, low in cost and high in sensitivity, and is suitable for field fast detection of batch samples.

The invention relates to a synthetic method for 5-methyl-2-hydrosulfuryl benzoic acid. The 5-methyl-2-hydrosulfuryl benzoic acid is a chelating agent; and reactants that are p-methyl thiophenol, catalytic agents (that can be aluminium chloride or iron trichloride) and oxalyl chloride are added in organic solvent (that can be petroleum ethers or ethers or methylene chloride or chloroform or chlorobenzene or nitrobenzene), so that 5-methyl-2-hydrosulfuryl benzoic acid is synthesized. The synthetic method achieves simple technology, products are easy to separate and purify, and the yield coefficient is high.

A process for preparing 2-trifluoromethyl-10-oxanone from p-trifluorotoluene and o-mercaptobenzoic acid includes nucleophilic substitution reaction on aryl ring to obtain diaryl thioether, and cyclization reaction with concentrated sulfuric acid. Its advantage is short period.

The invention discloses an SPR-SERS dual-mode sensor for detecting a disease nucleic acid marker as well as a preparation method and the application of the SPR-SERS dual-mode sensor. According to the SPR-SERS dual-mode sensor, an SPR sensing mode is realized by extracting integral optical density of dark field color in a dark field microscopic image, and a ratio type SERS sensing mode is realized by acquiring an intensity ratio of SERS characteristic peaks of ROX molecules and 4-mercaptobenzoic acid (4-MBA) molecules. For miRNA-652 detection, nucleic acid single chains C, H1 and H2 in the first reagent, the second reagent and the third reagent are DNA chains which are designed for miRNA-652 and have different nucleotide sequences. The SPR-SERS dual-mode sensor disclosed by the invention is simple to prepare, high in detection sensitivity and good in reliability, the detection limits of an SPR sensing mode and an SERS sensing mode on nucleic acid detection in serum can reach the level of flying mole per liter, and nucleic acid markers related to diseases can be detected in complex biological samples.

The invention discloses a biodegradable fluorescent poly-anhydride and method for preparing same, wherein the chemical constitution formula for poly-anhydride is [OC(O)ArXC(O)CHR'CHR'(O)CXArC(O)]#-[n], Ar is substituted or unsubstituted aromatic ring, X is NH, O or S, and the method for synthesizing consists of subjecting substituted or unsubstituted hydroxy benzoic acid, or substituted or unsubstituted amino benzoic acid, or substituted or unsubstituted mercapto benzoic acid to reaction with succinyl chloride or its derivative to obtain the corresponding diacid monomer, prepolymerizing the diacid monomer to obtain prepolymer, and further melting to obtain the fluorescent poly-anhydride.

The invention relates to a fruit and vegetable washing agent, and belongs to the field of washing products. Thiosalicylic acid is matched with dopamine hydrochloride and pretreated chitosan liquid components to prepare a multiplex crosslinked product containing sulfydryl, a micro-sphere is prepared from the multiplex crosslinked product and enzymolysis bovine adrenal gland serum, epsilon-polylysine is matched with sodium citrate to prepare a composite micro-sphere. the heavy metal residue adsorption strength of a system can be enhanced, the prepared composite micro-sphere is easily eluted andconveniently used and cleaned, organic matters in the bovine adrenal gland serum can soften fruit and vegetable skins, pesticide components are conveniently cleaned, a composite auxiliary is preparedfrom sodium carbonate, glutathione, trimethyl citrate and the like serving as raw materials, functional group phosphate structures similar to pesticide residue components and the functional groups such as ammonium are provided, and dissolution of the pesticide residue components is facilitated. The fruit and vegetable washing agent solves the problem that many traditional cleaning agents cannot effectively remove fruit and vegetable residual pesticides and heavy metal pollution components at present.

The invention belongs to the field of molecular magnetics, and particularly relates to a novel cobalt (III)-sulfur cluster-based coordination polymer with a single-molecule magnet property. The three-dimensional skeleton of the cobalt (III)-sulfur cluster-based coordination polymer provided by the invention is ([Co(III)3Co(II)2(mba)6(Hdtb)(H2O)4]n). Monocrystal XRD research shows that the polymer is composed of a trinuclear cobalt (III)-sulfur cluster structural unit and two mononuclear cobalt (II), a three-dimensional complex network structure is formed through bridging of a 2-mercaptobenzoic acid divalent anion ligand, and a cobalt (III) atom cluster unit is a trinuclear linear cobalt (III) cluster and serves as a construction unit in the coordination polymer. Magnetics research shows that the slow magnetic relaxation phenomenon of cobalt (II) ions is the characteristic behavior of a single-molecule magnet under the condition of no external direct-current magnetic field.

Synthesis of 5 - tri- n - butylstannum -2 - [2- (dimethyl aminemethylbenzensulfhydryl anilin is improved. It refers to synthesis of iodine labeled prosome. SnBu3 - ADAM is * I - ADAM' labeled prosome which has appetence and selectivity with 5- hydroxytryptamine translocator. It provides the diagnosis evidence for depression through studying distribution of * I - ADAM in brain to get distribution image brain internal. This invention provides an improved SnBu3 - ADAM synthesis route with 2,5-dibromonitobenzen and 2-sulfhydryl benzoic acid as start materials, of which both are cheap, has stable property. It yields higher than reports in literature.

The invention relates to a method for preparing an oil-displacing agent by modified charged polymer microspheres, belonging to the technical field of preparation of oil-displacing agents. The method comprises the steps of firstly mixing the substances such as styrene, meanwhile dropwise adding an acrylonitrile solution and a methyl blue solution, heating, cooling, performing suction filtration, washing and drying, then mixing with the substances such as 2-mercaptobenzoic acid, performing ultrasonic dissolution, heating, cooling, performing ultrasonic dispersion, filtering, collecting a filter cake, washing and drying, then placing into hydrofluoric acid, mixing, performing suction filtration and collecting the filter cake, drying, and mixing with distilled water, heating, adding ethylenediamine and formaldehyde, performing heat preservation, cooling, adjusting the pH value, performing suction filtration, collecting filter liquor, heating, adding the substances such as absolute ethyl alcohol, performing heat preservation, cooling, performing rotary evaporation, and drying to obtain the oil-displacing agent. The method has the beneficial effects that the oil-displacing agent prepared by the invention can reduce the binding force of crude oil with rock, so that the crude oil can be easily stripped, the displacement efficiency is improved by 10 to 15 percent, in a washing oil process, no damage of alkali, corrosion and scale.

The invention discloses a preparation method of a photoinitiator 1-chloro-4-propoxythioxanthone. The method comprises the following steps: step 1, carrying out condensation ring formation reaction: adding 2-mercaptobenzoic acid and p-chlorophenol into concentrated sulfuric acid and extracting to obtain a corresponding organic product; step 2, directly carrying out etherification reaction, withoutthe need of separation and purification: adding 1-halogenated propane and alkali into an obtained organic layer; finally, carrying out decompression and desolvation, de-coloring, filtering and vacuumdrying on an etherified product to obtain a final product, i.e., the photoinitiator 1-chloro-4-propoxythioxanthone. Compared with the prior art, the yield is greatly improved, reaction conditions aremoderate and post-treatment is simple; the preparation method is a production method suitable for industrialization.

The invention relates to a method for enhancing the SERS activity of silver decahedron nanoparticles by chloroauric acid. Generally speaking, the silver decahedron nanoparticles (DeAgNPs) and the trivalent gold ions are subjected to replacement reaction to obtain the silver core gold shell decahedron nanoparticles with different etching degrees, the decahedron nanoparticles are transferred to a silica gel substrate to form a two-dimensional film, and the surface Raman enhancement of the silver decahedron nanoparticles to 4-mercaptobenzoic acid (4-MBA) probe molecules is realized. Results showthat the silver decahedron nanoparticles etched by chloroauric acid with different concentrations correspond to the Raman enhancement of different degrees. The method is simple in raw material and lowin cost, and is safe and simple to operate; compared with the pure silver decahedron nano particles, the silver decahedron nanoparticles etched by the chloroauric acid (HAuCl4) prepared by the methoddisclosed by the invention are special in structure and good in stability and enable the SERS activity to be improved greatly. A method for detecting a to-be-detected object of the 4-thiosalicylic acid is simple and effective, is safe in operation process, is free of pollution, and can be applied to the water quality detection, biological detection and other aspects, and has the wide applicationprospects.

The invention relates to a preparation method of a heat conducing glue film with a high heat radiation performance, and belongs to the technical field of heat conducing glue film preparation. The preparation method comprises the following steps: at first, mixing ethylene-vinyl acetate copolymer and an antioxidant, heating the mixture, carrying out film casting, allowing the film to stand still for a while to cool the film; stretching the film, then allowing the film to stand still for a while to cool the film to obtain an ethylene-vinyl acetate microporous film, saving the ethylene-vinyl acetate microporous film for later use; then mixing acrylamide and 2-mercapto benzoic acid, heating, filtering, washing and drying the filter residues to obtain composite microgel, then mixing microgel with anhydrous ethanol, carrying out ultrasonic vibration and separation, mixing with deionized water, dropwise adding a silver nitrate solution, carrying out water bath heating, dropwise adding an ammonia liquor solution, allowing the mixed solution to stand still to carry out aging to obtain silver ion composite gel; finally soaking the ethylene-vinyl acetate microporous film in the silver ion composite gel, carrying out ultrasonic vibration, allowing the system to stand still, drying, performing hot pressing, finally allowing the system to stand still, and cooling. The prepared heat conducing glue film has a good heat radiation performance, the heat radiation performance is improved by 15 to 17%, and the heat conductivity can reach 2.55 to 2.65 W / M.K.

The invention relates to a preparation method of a benzoic acid functionally-modified non-stoichiometric molybdenum oxide nanocrystal. The non-stoichiometric molybdenum oxide nanocrystal with a near-infrared photothermal conversion effect is prepared by introducing p-mercaptobenzoic acid to the surface of a molybdenum trioxide nanoparticle. The invention has the advantages that (1) the prepared functionally-modified non-stoichiometric molybdenum oxide nanocrystal has excellent photothermal conversion performance, and surface active group is provided for the nanoparticle through functionalizedmodification; and (2) the prepared non-stoichiometric molybdenum oxide nanoparticle has excellent photothermal conversion performance and good dispersibility and stability, and can also be used for photothermal sensing detection and photothermal therapy (PTT) of different models of different target objects.

The invention relates to the technical field of photo initiators, in particular to a hioxanthone photo initiator and a preparation method thereof. The cyclic acetal base-containing thioxanthone photo initiator has a chemical structural formula shown in the specification, wherein n=0 or 1; and R=H, CH3, CH2CH3, CH2CH2CH3, CH2CH2CH2CH3, C(CH3)3, CHO, COOH, or OH, C1, F or I. The preparation method comprises the following steps of: adding one molar portion of 2-mercaptobenzoic acid into five mol portions of 1, 3-benzodioxole pentane or 1, 3-benzodioxole hexane and derivatives thereof; slowly dropwise adding concentrated acid, wherein the volume of the concentrated acid is 1.5 times the molar portion of 2-mercaptobenzoic acid calculated by L; reacting for 1 to 24 hours at the temperature of 0 to 70 DEG C; carefully pouring the mixture to boiling water , cooling and filtering; recrystallizing by utilizing a component solvent of dioxane and water; and drying in vacuum to obtain the cyclic acetal base-containing thioxanthone.

The invention discloses an optical lens composite resin material with high refractive index and high light transmittance. The optical lens composite resin material comprises the following components in parts by weight: 60-84 parts of matrix resin, 1-4 parts of a UV absorbent and 0.05-0.2 parts of an antioxidant, wherein the matrix resin is prepared according to the following steps: (1) preparing p-mercaptobenzoic acid surface modified nano zinc sulfide; (2) preparing hydroxyl-terminated polystyrene; and (3) dissolving the hydroxyl-terminated polystyrene synthesized in the step (2) in a tetrahydrofuran solvent, then adding p-mercaptobenzoic acid surface modified nano zinc sulfide, performing reacting for 3-5 hours under a stirring condition, and then hydrolyzing and drying to obtain the matrix resin. According to the invention, polystyrene is subjected to hydroxylation modification, a polystyrene system is endowed with reactive active hydroxyl groups, and terminal hydroxyl groups and carboxyl groups on the surface of the nano zinc sulfide can be subjected to polycondensation, so that the dispersity of the nano zinc sulfide in the polystyrene system is greatly improved, the resin material has higher refractive index, and the high transparency of the resin is ensured.