66results about How to "Easy purification" patented technology

The invention provides a new method for synthesizing maxacalcitol and an intermediate thereof. According to the method, the maxacalcitol is creatively synthesized through the steps of taking vitamin D2 as an initial raw material, obtaining a compound shown as a formula II, oxidizing, chirally reducing, connecting a side chain, introducing a hydroxyl group to a C-1 position, photochemically overturning and the like.

The invention relates to a preparation method of high-purity fluoroethylene carbonate. The preparation method comprises the following steps: 1) reacting chloroethylene carbonate raw materials with hydrogen fluoride liquid to obtain a mixture; 2) adding metal oxides to the mixture for deacidification reaction, and filtering to obtain a filtrate; 3) adding Solvents are mixed, and the temperature is lowered to crystallize to obtain fluoroethylene carbonate crystals, and water is removed to obtain high-purity fluoroethylene carbonate. The preparation method of high-purity fluoroethylene carbonate of the present invention uses chloroethylene carbonate and anhydrous hydrogen fluoride liquid as raw materials to carry out liquid-liquid reaction, and prepares high-purity fluoroethylene carbonate through the processes of acid removal reaction, temperature-lowering crystallization, and temperature-raising water removal process , the purity of the obtained product is more than 99.5%. The preparation method has simple process control, less side reactions, easy purification, high purity of the reaction product, low cost, and is convenient for industrialized production.

The invention provides a gasification process for producing synthesis gas from garbage and biomass raw materials, which relates to a gasification processing technique of garbage and biomasses. The gasification process is characterized in that the technological process mainly comprises a raw material solid matter process, a gas phase circulation loop, a calcium oxide circulation loop and a synthesis gas drawing process; one or a mixture of more garbage, the biomasses and coal is sent into a gasification furnace to perform gasification so as to generate the synthesis gas; and simultaneously, calcium oxide is sent into the gasification furnace, an exothermic reaction of absorbing carbon dioxide by the calcium oxide provides the heat required by the gasification reaction in the furnace, and water vapor is sent into a plasma spraying gun and is heated to more than 3,100 DEG C to generate H2, O, O2 and H2O<*> which are sprayed into the gasification furnace to perform reactions with the garbage and the biomasses and supply heat into the furnace. The gasification process adopts a measure to spray the calcium oxide into the furnace to not only greatly reduce the electric energy consumptionof the plasma spraying gun, but also improve the quality and the yield of the synthesis gas, thus the aim of transforming the garbage and the biomasses into clean energy can be achieved easily.

The invention discloses an anti-tumor vaccine targeting VEGF and mucin1, coding genes, expression vectors, expression engineering bacteria and applications, and belongs to the field of biotechnology. The anti-tumor vaccine fusion protein uses VEGF165, VEGF165b or its corresponding modified VEGF mutant as the epitope carrier, and at least one epitope peptide segment of the tumor-associated antigen mucin1 is connected to the N-terminal or C-terminal of the carrier to form a dual-targeting effective antitumor vaccines. VEGF in the vaccine can not only serve as an epitope carrier to enhance the antigenicity of the mucin1 epitope connected to it, kill tumor cells overexpressing mucin1, but also act as an antigen itself to produce antibodies against VEGF, inhibit tumor angiogenesis, and cut off tumor cells. nutrient supply. At the same time, the epitope carrier has a heparin binding domain, which can be combined with heparin agarose gel, which is beneficial to the subsequent protein purification operation.