90results about How to "Increase chance of binding" patented technology

The invention relates to a pail floating type power accumulator. A floating pail device is arranged in the cavity of a vertical shell, and the power accumulator comprises a shell, the floating pail device, a lower cover and an upper cover, wherein, the lower cover is provided with a valve seat and an oil inlet; the upper cover is provided with a gas charging valve; the floating pail device is arranged in the cavity of the shell to separate a gas storage chamber and a liquid storage chamber from the cavity of the sell, the gas storage chamber is used for storing pre-charged high pressure gas, the liquid storage chamber is used for storing incompressible hydraulic oil, and the two chambers are communicated with each other through the gap between the outer edge of the floating pail device and the inner edge of the shell. If the pressure of hydraulic oil provided by a generating system excesses the upper limit, the hydraulic oil can be led into the gas storage space of the cavity of the floating bail to be stored temporarily through a communicating pipe; when in feeding oil, the hydraulic oil is preferably discharged from the cavity of the floating bail, and residual oil mass can not be accumulated, so as to protect the power accumulator not to lose efficacy because of exceeding the limit. In addition, the gap is left between the floating pail device and the shell, thereby generating no abrasion, being capable of rapidly responding operational requirement, prolonging the service life of the power accumulator and reducing maintenance cost.

A lead compound discovery and synthesis method based on quantum group intelligent optimization comprises the steps of 1, performing combinatory prediction on a new lead compound, initializing modeling, confirming a target, and carrying out quantum screening; 2, performing activity evaluation and quantum group intelligent optimization, to be specific, establishing a training set and a test set, training a quantum group, and calculating correct rate of the test set; 3, optimizing pharmaceutical effect, and eliminating toxicological activity; 4, carrying out animal and clinical experiments. The lead compound is constructed by quantum group intelligent optimization; active ingredients mainly including chemical ingredients and effective ingredients mainly including pharmacologically active ingredients are described accurately; success rate of new drug design by quantum screening and quantum group intelligent optimization is higher; the design cost of new drugs can be greatly reduced; a quantum group intelligent optimization model is suitable for performing lead compound simulation experiments on a computer more truly; the truer drug design model and method can be provided through the combination of animal and clinical experiments.

The invention is a kind of organic electricity laser illuminating element, which is mainly made up of base board, positive layer, illuminating layer, and cavity resistant layer. The positive layer is set on the base board; the illuminating layer is set on the positive layer; the cavity resisting layer is set on the illuminating layer; the negative layer is set in the cavity resistant layer. The illuminating layer is organic material mixed with cavity conduction material and phosphorescence material, the density of the two materials is between forty percentages to sixty percentages.

The invention provides a method for remarkably improving the strength of a detection signal of a lateral flow immunochromatography detection test strip. The method for improving the strength of the detection signal comprises the following steps: (a) after mixing a sample and an antibody marked on a fluorescent microsphere in vitro, adding a mixture onto a sample pad of chromatography test paper; (b) after combining a matter to be analyzed in the sample with the antibody marked on the fluorescent microsphere, forming a compound to be detected; gradually dispersing the compound to be detected toa nitrocellulose membrane along a chromatography flow; (c) dividing a detection line and a quality control line on the nitrocellulose membrane; (d) carrying out perforation modification on the nitrocellulose membrane between the sample pad and the detection line to obtain a modification region formed by 1 to 10 rows of modification holes. According to the method provided by the invention, the aims of increasing the probability of capturing the compound to be detected, reducing the time of uniformly blending in vitro, improving the testing sensitivity, reducing the measurement limit value and / or improving the detection signal can be realized.

The invention discloses a reactor prepared in a mode of simultaneously fixing chloroperoxidase to the inner and outer walls of surface modified magnetic halloysite nanotubes and application. A methodcomprises the steps that magnetic materials, namely ferroferric oxide, are modified on the halloysite nanotubes firstly; then 3-aminopropyltriethoxysilane and polyethyleneimine are sequentially modified on the surfaces of the magnetic halloysite nanotubes, so that the inner and outer walls of the modified magnetic halloysite nanotubes are both positively charged; and finally, the chloroperoxidaseis fixed to the interiors of the tubes through physical absorption and fixed to the outer walls of the tubes through covalent binding, and the enzyme reactor is obtained. On the basis of simultaneousfixing of the inner and outer walls, the immobilization amount of the chloroperoxidase is increased, the obtained enzyme reactor is easy, convenient and fast to recycle, 92.20% of catalytic activity can be kept after reuse for nine times, heat stability is better than heat stability of free enzymes at 70-80 DEG C, toleration is good in organic solvents such as DMF, methanol and acetonitrile, the degradation efficiency for degrading rifaximin is high, and when the content of the rifaximin is within 50 [mu]g / mL, the degradation efficiency can reach 90% or above.

The invention discloses a drug fusant of a specific binding GLP-1 (Glucagon-like peptide-1) receptor, and also discloses a preparation method of the drug fusant and applications of the medicament fusant in preparing diabetes drug by utilizing the drug fusant.

The invention discloses an integral gearbox of a rod roller, wherein a box body of the integral gearbox is an integral structure. The box body is provided with a first transmission shaft, a second transmission shaft, a third transmission shaft, a fourth transmission shaft, a gap bridge shaft, a reversible joystick and a speed-change joystick. The first transmission shaft is at least provided with two or more speed-change driving gears with different diameters; the second transmission shaft is provided with a speed-reduction gear, a speed-change passive gear and a speed-change sliding gear, and the speed-change sliding gear is provided with a shift fork which is connected with the speed-change joystick; the third transmission shaft is provided with a speed-reduction passive gear and two reversing active gears; the fourth transmission shaft is provided with two reversion passive gears and a reversion sliding gear, the reversion sliding gear is arranged between the two reversion passive gears and is provided with a shift fork which is connected with the reversible joystick; and the gap bridge shaft is arranged between the fourth transmission shaft and the third transmission shaft and is provided with a gap bridge gear. The integral gearbox of the road roller, disclosed by the invention, has the characteristics of small size, reasonable structure, easiness in manufacturing, low cost, convenience and flexibility in operation and control, and high work efficiency.

The invention discloses a method for preparing high-yield cellulose nano-microfilaments in a low energy consumption mode through enzyme-assisted mechanical grinding. The cellulose nano-microfilamentswith the high yield and the smaller and more uniform size are prepared in the low energy consumption mode through a mechanical grinding and enzyme after-treatment method, an enzyme pre-treatment, mechanical grinding and enzyme after-treatment method, or a compound enzyme pre-treatment and mechanical grinding method. The method has the advantages that (1) the yield of the cellulose nano-microfilaments is increased substantially; (2) the prepared cellulose nano-microfilaments have the smaller size and better size uniformity; and (3) meanwhile, energy consumption of the mechanical grinding process is substantially lowered, and the nanocellulose with the more uniform size is produced in industrial, efficient, environment-friendly and pollution-free modes.

The invention discloses a method for fertilizing hybrid paddy rice for seed production by applying a multi-rotor-wing remotely piloted vehicle. The method applies the multi-rotor-wing remotely piloted vehicle for hedgehopping to agitate air above a field parcel for the seed production of the hybrid paddy rice, and a formed local low-energy air eddy helps paternal pollens to be blown off among maternal rows, and is convenient for maternal stigmas to accept more paternal pollens, so that an outcrossing setting percentage can be increased by 1.2-2.5%. The multi-rotor-wing remotely piloted vehicle in the method for fertilizing the hybrid paddy rice for the seed production by applying the multi-rotor-wing remotely piloted vehicle continuously flies back and forth in a transverse W shape as a flight path relative to the field parcel for the seed production of the hybrid paddy rice, and repeatedly flies for 3-6 times above a same field parcel at time intervals of 10-20 minutes each time and at flight heights of 2-8 meters. As an area, which is influenced by the eddy generated by the hedgehopping of the multi-rotor-wing remotely piloted vehicle, of a ground target field parcel for the seed production of the hybrid paddy rice is large, parental row ratios are increased to 3:(24-42); the work efficiency of vast continuous fertilization is 10-15 times higher than that of manual flower pulling fertilization; thus, the labor cost is saved massively. The method for fertilizing the hybrid paddy rice for the seed production by applying the multi-rotor-wing remotely piloted vehicle is particularly suitable for being used by an enterprise carrying out large-scale seed production.