91results about How to "Increase chance of binding" patented technology

The present invention relates to a defoaming agent for paper-making pulp. Its composition includes the following components: (1), 0.1-20% of fatty alcohol; (2), 10-80% of fatty alcohol polyether; (3), 5-70% of general group modified polyether, said general group modified polyether is obtained by using polyether and end-capping material methane chloride, butane chloride or fatty acid and making them undergo the process of end-capping modification reaction; (4), 0.1-30% of polyether modified organic silicone (called 'silicopolyether' for short), said silicopolyether is obtained by using hydrogen-containing silicone oil and unsaturated polyether through addition reaction; and (5), 0.1-20% natural oil and fat.

The invention relates to a method for analyzing and detecting pathogenic microorganisms, which comprises the following steps: (1) filling immunological microspheres modified by antibodies into an immunological recognition / enrichment cavity; (2) introducing a sample solution to be measured into the immunological recognition / enrichment cavity to be recognized, captured and enriched by the immunological microspheres; (3) respectively transferring a cracking agent and a biological luminous reagent into the immunological recognition / enrichment cavity to carry out cracking reaction and biological luminous reaction with the enriched pathogenic microorganisms to generate a luminous composite; and (4) eluting the luminous composite generated in the step (3) with a buffer solution, and analyzing the pathogenic microorganisms in the sample to be measured through luminous detection. The method realizes separation / enrichment, inclusion cracking, biological luminous reaction and quantitative detection of the pathogenic microorganisms on the same micro-fluidic chip, not only reduces the consumption of the sample and the reagent but also avoids complicated operation, overlong analysis time and sample loss caused by a plurality of analysis steps or processes, and improves the analysis speed, the detection accuracy and the detection sensitivity.

The invention provides an RGD polypeptide coordination complex of a radioactive nuclide label. According to the structure of the coordination complex, the radioactive nuclide is selected from 64Cu, 68Ga, 111In, 62Cu, 67Cu, 67Ga, 86Y, 89Zr or 18F; the ligand is a ligand compound containing an RGD structure, which is shown in a formula (I). The coordination complex has stronger ligand stability and high target / non-target ratio, and the appetency of the ligand with integrin AlphavBeta3 is stronger. The invention further provides a preparation method of the coordination complex, and an application of the coordination complex in preparing tumor developers.

The invention discloses a high-temperature low-alkaline dyeing method for double-monochlorotriazine reactive dyes. The method is characterized by comprising the following steps: putting a material to be dyed into a dye bath according to the bath ratio of 1:8-1:30, adding 10-80g / L of electrolyte, and running for 3-5min; adding 10-20g / L of mixed alkalis, running for 3-5min, and adjusting the pH value of the initial dye bath to be 9-10; adding double-monochlorotriazine type reactive dye, and running for 3-5min; heating up to 130 DEG C according to the speed of 1-3DEG C / min, and carrying out heat-preservation dyeing for 30-45min; discharging liquid in a cooling way, and stopping dyeing. According to the method provided by the invention, the double-monochlorotriazine reactive dye and the disperse dye can be jointly batched with each other, and the dyeing can be carried out on a terylene / cotton blended fabric by a high temperature-batch method. Therefore, the producing flow path for dyeing the terylene-cotton fabric can be obviously shortened, the production efficiency can be improved, the energy consumption can be greatly reduced, the sewage discharge can be reduced, and the method is suitable for the low-carbon, environment-friendly, high-efficiency and ecological dyeing and finishing direction.

The invention discloses a method for selectively enriching scandium from Bayer process red mud. The method is characterized in that the Bayer process red mud is used as a raw material, the red mud isfully wet by adding an appropriate amount of water, the red mud is sulphated by using concentrated sulfuric acid and is then calcined at a high temperature, the solid calcined product is mechanicallyactivated by grinding and is then subjected to four-stage water immersion and washing, so that a scandium-rich leaching solution, scandium-rich washing liquid and low-alkali iron-rich slag are obtained. The method enables most of scandium to be leached, but the leaching rates of impurity iron and aluminum are low, and silicon and titanium are not leached substantially, so that the formation of colloidal silicate in the leaching solution is avoided, and the selective absorption and extraction of the scandium in the subsequent leaching solution are facilitated; the generated sulfur dioxide and sulfur trioxide can be reused in the preparation of sulfuric acid, so that the production of a large amount of waste acid is avoided; the pH of the low-alkali iron-rich slag is close to neutral, and can be used in the industries such as iron making, adsorbents, ceramics, construction and the like, so that a new way is provided for the extraction of the scandium and the comprehensive utilization ofthe red mud.

The invention provides a photoelectric element, which comprises an n-type covering layer, a p-type covering layer and a luminous layer, wherein the luminous layer is positioned between the n-type covering layer and the p-type covering layer. The luminous layer has a multi-quantum well structure which is formed by alternately stacking a plurality of potential barrier layers and a plurality of welllayers, wherein the potential barrier layer closest to the p-type covering layer is doped with impurities capable of changing the potential barrier of the potential barrier layer to form a potential barrier modulation layer. The photoelectric element has the advantage of improving the luminous efficiency.

The invention provides a nitride bottom layer, a light emitting diode and a bottom layer preparation method. An aluminium nitride layer is deposited through a physical vapor method. In the deposition process, oxygen elements are put in a reaction cavity so as to form the aluminium nitride layer containing the oxygen elements. Plasma with the physics property is used to treat the surface of the aluminium nitride layer, the oxygen element content on the surface of the aluminium nitride layer is reduced, and an aluminium nitride modified layer is formed, wherein the surface morphology of the modified layer is consistent with that of the aluminium nitride layer in the above step. Through reduction of the oxygen element content on the surface of the modified layer, the surface energy state of the modified layer is reduced, the bonding probability with a buffer layer is increased, and the crystal lattice difference with the buffer layer is lowered. The bottom layer stress of the light emitting diode is reduced.

The invention discloses a preparation method for hydrogenated crystalline state nanometer carborundum films under low temperature. The method comprises the following steps: first, placing the rinsed substratum on the substrate plate of the chemical vapor deposition device strengthened by helicon plasma, and then vacuumizing the reaction chamber of the chemical vapor deposition device strengthened by helicon plasma, and rinsing the substrate plate and the internal walls of the chamber by hydrogen plasma; then, reheating the substrate plate and inflating reaction gas into the reaction chamber to adjust the air pressure, and applying magnetic field to the plasma production chamber of the chemical vapor deposition device strengthened by helicon plasma, and turning on the RF power supply to start the deposition of carborundum films to obtain the carborundum films sample; finally, cooling the chamber off to room temperature under the protection of hydrogen and taking out the sample from the chamber to complete the deposition of hydrogenated nanometer crystalline state nanometer carborundum films. Hydrogenated nanometer crystalline state nanometer carborundum films can be prepared by using the method of the invention under a low temperature.

The invention discloses a quantum dynamic computation method for lead compounds. The quantum dynamic computation method for the lead compounds includes the steps that a quantum dynamic model base of the lead compounds is established; related information of the lead compounds is quantized, and a database of the lead compounds is established; active compounds are discovered at random through quantumscreening; the lead compounds and active ingredients meeting required properties are searched in a database system, true random numbers generated through a quantum dynamic model are combined, and various compound models are established through a quantum screening mechanism; through the quantum dynamic model, mutual effects between active compound molecules and mutual effects between biological cells are established. The chemical effect is checked according to a quantum dynamic evolution mechanism; a synthetic active compound is subjected to a later quantum test simulation experiment, and a quantum dynamic model when compound molecules are combined with target spot protein is established. According to the quantum dynamic computation method for the lead compounds, the mutual effects betweenmolecular structures are subjected to evolution analysis with the quantum dynamic method, and the lead compounds corresponding to some pathologic structure can be obtained at higher accuracy and lower cost.

The invention belongs to the field of papermaking technologies and materials, and particularly relates to para-aramid nanofiber / high-performance carbon fiber composite paper and a preparation method thereof. By utilizing the characteristics of a large specific surface area, easy dispersion in an aqueous solution and the like of para-aramid nanofibers, the para-aramid nanofibers can replace a traditional wet strength agent and an adhesive for pulp; the para-aramid nanofibers can be fully and uniformly mixed with a high-performance carbon fiber solution, and a wet paper sheet of para-aramid and carbon fibers is prepared through wet papermaking; then a para-aramid nanofiber dispersion liquid is subjected to spraying and sizing on the surface of the aramid wet paper sheet; then compounding, drying and forming are conducted; and thus, the sprayed and compounded paper sheet can remarkably improve the uniformity and mechanical strength of the composite paper, improve the production efficiency of a composite paper-based material and the like, and can fully realize the compounding of the carbon fibers and the aramid fibers. A composite material prepared by using the method has good heat resistance and chemical stability and excellent heat conduction and electric conduction performance.

The invention relates to a pail floating type power accumulator. A floating pail device is arranged in the cavity of a vertical shell, and the power accumulator comprises a shell, the floating pail device, a lower cover and an upper cover, wherein, the lower cover is provided with a valve seat and an oil inlet; the upper cover is provided with a gas charging valve; the floating pail device is arranged in the cavity of the shell to separate a gas storage chamber and a liquid storage chamber from the cavity of the sell, the gas storage chamber is used for storing pre-charged high pressure gas, the liquid storage chamber is used for storing incompressible hydraulic oil, and the two chambers are communicated with each other through the gap between the outer edge of the floating pail device and the inner edge of the shell. If the pressure of hydraulic oil provided by a generating system excesses the upper limit, the hydraulic oil can be led into the gas storage space of the cavity of the floating bail to be stored temporarily through a communicating pipe; when in feeding oil, the hydraulic oil is preferably discharged from the cavity of the floating bail, and residual oil mass can not be accumulated, so as to protect the power accumulator not to lose efficacy because of exceeding the limit. In addition, the gap is left between the floating pail device and the shell, thereby generating no abrasion, being capable of rapidly responding operational requirement, prolonging the service life of the power accumulator and reducing maintenance cost.

The invention discloses a semicoke supported tar steam reforming catalyst as well as a preparation method and an application thereof, and the semicoke supported tar steam reforming catalyst takes low-rank coal pretreated by an oxidant as a catalyst carrier precursor and Ni as a metal active component. In the invention, the low-rank coal being low in cost is used as a catalyst carrier precursor, sothat the surface acid sites of the catalyst are enriched, the carrier-metal interaction is enhanced, the atom utilization efficiency is improved, and the activity of the catalyst is further improved.And the catalyst can be used for catalyzing biomass or low-rank coal gasification tar steam reforming, and has higher carbon conversion rate.

A lead compound discovery and synthesis method based on quantum group intelligent optimization comprises the steps of 1, performing combinatory prediction on a new lead compound, initializing modeling, confirming a target, and carrying out quantum screening; 2, performing activity evaluation and quantum group intelligent optimization, to be specific, establishing a training set and a test set, training a quantum group, and calculating correct rate of the test set; 3, optimizing pharmaceutical effect, and eliminating toxicological activity; 4, carrying out animal and clinical experiments. The lead compound is constructed by quantum group intelligent optimization; active ingredients mainly including chemical ingredients and effective ingredients mainly including pharmacologically active ingredients are described accurately; success rate of new drug design by quantum screening and quantum group intelligent optimization is higher; the design cost of new drugs can be greatly reduced; a quantum group intelligent optimization model is suitable for performing lead compound simulation experiments on a computer more truly; the truer drug design model and method can be provided through the combination of animal and clinical experiments.

The invention relates to a transferring point dust suppression device and method. The device is arranged at the transferring position of an upper-stage belt and a lower-stage belt. The device comprises a discharge pipe, an ultrasonic smoke nozzle, a dust suppression cover, baffle plates, a return pipe, a sealing part and a dust blocking curtain. An induced airflow calculation method is invented, aformula for calculating the size of the induced airflow in different working conditions and devices is provided, guidance is provided for reasonably setting the parameters such as the fogdrop particles and the spraying volume of the ultrasonic smoke nozzle, and the purpose of reducing the dust suppression energy consumption is achieved. Ultrasonic waves are used for generating frog so that the space of the discharge pipe can be humidified, in cooperation with the flow blocking effect of the baffle plates and the dust blocking curtain and the pressure relief effect of the return pipe, dust carried in the airflow settles under the gravity effect, the combination probability of the frog and dust is improved through kinetic energy of the induced airflow, and the dust removal effect is improved. The transferring point dust suppression device and method are suitable for dust suppression of the bulk material belt conveying and transferring process without special requirements on the materialmoisture content, such as dust suppression of the belt conveying processes such as coal, iron ore, building quarrying, sintering and gravel loading and unloading.

The invention is a kind of organic electricity laser illuminating element, which is mainly made up of base board, positive layer, illuminating layer, and cavity resistant layer. The positive layer is set on the base board; the illuminating layer is set on the positive layer; the cavity resisting layer is set on the illuminating layer; the negative layer is set in the cavity resistant layer. The illuminating layer is organic material mixed with cavity conduction material and phosphorescence material, the density of the two materials is between forty percentages to sixty percentages.

The invention provides a method for remarkably improving the strength of a detection signal of a lateral flow immunochromatography detection test strip. The method for improving the strength of the detection signal comprises the following steps: (a) after mixing a sample and an antibody marked on a fluorescent microsphere in vitro, adding a mixture onto a sample pad of chromatography test paper; (b) after combining a matter to be analyzed in the sample with the antibody marked on the fluorescent microsphere, forming a compound to be detected; gradually dispersing the compound to be detected toa nitrocellulose membrane along a chromatography flow; (c) dividing a detection line and a quality control line on the nitrocellulose membrane; (d) carrying out perforation modification on the nitrocellulose membrane between the sample pad and the detection line to obtain a modification region formed by 1 to 10 rows of modification holes. According to the method provided by the invention, the aims of increasing the probability of capturing the compound to be detected, reducing the time of uniformly blending in vitro, improving the testing sensitivity, reducing the measurement limit value and / or improving the detection signal can be realized.

The invention provides a method for coating estriol antibodies on the surfaces of magnetic corpuscules for the estriol immunoassay detection. The method is technically characterized in that the antibodies of the antigen to be detected are conjugated with the surfaces of magnetic corpuscules via covalent bonds. The magnetic corpuscules are completely washed before being coated, the magnetic corpuscules and the estriol antibody serum are further added to a specified buffer solution system, and react while vibrating at the room temperature. The estriol antibody-coated magnetic corpuscules can be directly involved in an immunoreaction so as to be applied in the immunoassay detection of the estriol after being enclosed. During the processes of the antibody coating and the assay measurement, a magnetic separator can be combined to carry out the precipitation separation. The method has the advantages of convenient operation and low cost. The process of the reaction can be completed in one step without large valuable instruments, and the estriol antibodies can be combined with various detection instruments, and are suitable for generalization.

The invention discloses a reactor prepared in a mode of simultaneously fixing chloroperoxidase to the inner and outer walls of surface modified magnetic halloysite nanotubes and application. A methodcomprises the steps that magnetic materials, namely ferroferric oxide, are modified on the halloysite nanotubes firstly; then 3-aminopropyltriethoxysilane and polyethyleneimine are sequentially modified on the surfaces of the magnetic halloysite nanotubes, so that the inner and outer walls of the modified magnetic halloysite nanotubes are both positively charged; and finally, the chloroperoxidaseis fixed to the interiors of the tubes through physical absorption and fixed to the outer walls of the tubes through covalent binding, and the enzyme reactor is obtained. On the basis of simultaneousfixing of the inner and outer walls, the immobilization amount of the chloroperoxidase is increased, the obtained enzyme reactor is easy, convenient and fast to recycle, 92.20% of catalytic activity can be kept after reuse for nine times, heat stability is better than heat stability of free enzymes at 70-80 DEG C, toleration is good in organic solvents such as DMF, methanol and acetonitrile, the degradation efficiency for degrading rifaximin is high, and when the content of the rifaximin is within 50 [mu]g / mL, the degradation efficiency can reach 90% or above.

The invention discloses a drug fusant of a specific binding GLP-1 (Glucagon-like peptide-1) receptor, and also discloses a preparation method of the drug fusant and applications of the medicament fusant in preparing diabetes drug by utilizing the drug fusant.

The invention discloses a method for preparing high-yield cellulose nano-microfilaments in a low energy consumption mode through enzyme-assisted mechanical grinding. The cellulose nano-microfilamentswith the high yield and the smaller and more uniform size are prepared in the low energy consumption mode through a mechanical grinding and enzyme after-treatment method, an enzyme pre-treatment, mechanical grinding and enzyme after-treatment method, or a compound enzyme pre-treatment and mechanical grinding method. The method has the advantages that (1) the yield of the cellulose nano-microfilaments is increased substantially; (2) the prepared cellulose nano-microfilaments have the smaller size and better size uniformity; and (3) meanwhile, energy consumption of the mechanical grinding process is substantially lowered, and the nanocellulose with the more uniform size is produced in industrial, efficient, environment-friendly and pollution-free modes.

The invention discloses a method for fertilizing hybrid paddy rice for seed production by applying a multi-rotor-wing remotely piloted vehicle. The method applies the multi-rotor-wing remotely piloted vehicle for hedgehopping to agitate air above a field parcel for the seed production of the hybrid paddy rice, and a formed local low-energy air eddy helps paternal pollens to be blown off among maternal rows, and is convenient for maternal stigmas to accept more paternal pollens, so that an outcrossing setting percentage can be increased by 1.2-2.5%. The multi-rotor-wing remotely piloted vehicle in the method for fertilizing the hybrid paddy rice for the seed production by applying the multi-rotor-wing remotely piloted vehicle continuously flies back and forth in a transverse W shape as a flight path relative to the field parcel for the seed production of the hybrid paddy rice, and repeatedly flies for 3-6 times above a same field parcel at time intervals of 10-20 minutes each time and at flight heights of 2-8 meters. As an area, which is influenced by the eddy generated by the hedgehopping of the multi-rotor-wing remotely piloted vehicle, of a ground target field parcel for the seed production of the hybrid paddy rice is large, parental row ratios are increased to 3:(24-42); the work efficiency of vast continuous fertilization is 10-15 times higher than that of manual flower pulling fertilization; thus, the labor cost is saved massively. The method for fertilizing the hybrid paddy rice for the seed production by applying the multi-rotor-wing remotely piloted vehicle is particularly suitable for being used by an enterprise carrying out large-scale seed production.

The invention discloses an oil purifier for a motor vehicle. The oil purifier comprises a filtering seat, an oil storage cup, a water accumulating cup, a water drain valve set, a heat controlling device assembly, a magnetic filter element assembly and an infrared radiation heater; the magnetic filter element assembly comprises a bracket, a filter element, a strong magnetic sheet and a silk wadding filtering layer, wherein the filter element is positioned at the inner side of the bracket, and the strong magnetic sheet and the silk wadding filtering layer are positioned at the outer side of thebracket; the heat controlling device assembly comprises a valve plug upper body, a valve plug lower body and a thermal sensor which are connected sequentially; the filtering seat is provided with an oil inlet and an oil outlet; the oil inlet is connected with an oil-water separator; and the oil outlet is provided with a temperature sensor. According to the invention, a series of difficulties and problems which occur during the filtration and removal of micro metal crystal particles contained in fuel oil and high viscosity of the fuel oil can be solved, the limitations of filtration and removal of particle diameter are overcome, high product manufacturing cost is reduced, thus a series cold using difficulties and problems caused by high viscosity because of the cooling of a diesel are solved.

The invention discloses a method for enhancing the escherichia coli resisting performance of polyethyleneimine. According to the method, mannose is decorated on the branching type polyethyleneimine, the decoration method is simple, the reaction time is short, the cost is low, and the minimum bacteriocidal concentration of polyethyleneimine decorated with the mannose to escherichia coli is 10 [mu]g / mL, and is reduced by 22 times compared with the minimum bacteriocidal concentration (220 [mu]g / mL) of the polyethyleneimine to the escherichia coli. And meanwhile, after HeLa cells added with 500 [mu]g / mL of antibacterial agents are cultured for 24 h, the activity of the cells added with the polyethyleneimine decorated with the mannose is maintained at 75%, and the activity of the cells added with the polyethyleneimine is decreased to 56%. The method for enhancing the escherichia coli resisting performance of the polyethyleneimine obviously enhances the sterilizing rate of the polyethyleneimine to the escherichia coli and reduces the cytotoxicity.

The invention discloses a preparation method for glycine-lysine-proline insulin crystals. The method includes the step of adding Zn ions to a crystalline solution containing glycine-lysine-proline insulin in a method of two or more steps for two or more steps of crystallization, wherein according to the mass ratio of Zn to glycine-lysine-proline insulin, the amount of the Zn ions added in the first step of crystallization is 0.1%-0.8%, the amount of the Zn ions added in other steps of crystallization is 0.1% or more, and the total amount of the Zn ions added in all the steps is 0.4% or more. The preparation method can prepare high-quality and high-yield glycine-lysine-proline insulin crystals, and is prone to industrialized production of glycine-lysine-proline insulin.

The invention relates to a nitride semiconductor structure and a semiconductor light-emitting component. The nitride semiconductor structure is mainly characterized in that a light-emitting layer is arranged between an N-type semiconductor layer and a P-type semiconductor layer, and a quaternary carrier active layer is arranged between the light-emitting layer and the P-type semiconductor layer and is made of AlxInyGa1-x-yN, wherein the x and the y are numerical values meeting the conditions that the x is larger than zero and smaller than one, the y is larger than zero and smaller than one, and a sum of the x and the y is larger than zero and smaller than one. The semiconductor light-emitting component is characterized in that the nitride semiconductor structure, an N-type electrode and a P-type electrode are arranged on a substrate, and the N-type electrode and the P-type electrode supply power energy in a matched mode. In this way, compared with a publicly-known P-AlGaN electronic barrier layer, the nitride semiconductor structure and the semiconductor light-emitting component can improve the multi-quantum-well structure entered effect of electron holes, and meanwhile the aim that electrons are prevented from entering the P-type semiconductor layer by restraining electron escaping is achieved; the electron and electron hole combination rate is increased, and the light-emitting efficiency is further improved.

The present invention discloses the preparation process of far infrared ceramic honeycomb type heat resisting energy saving furnace plate and belongs to the field of environment friendly energy saving product technology. The materials comprising silica 58-78wt%, alumina 16.9-25.5wt%, potassium oxide 1-5wt%, zirconium oxide 1-3 wt%, titania 0.1-0.5 wt%, sodium oxide 1-3wt% and calcium oxide 2-5wt% are produced into the far infrared ceramic honeycomb type heat resisting energy saving furnace plate through mixing, high temperature sintering and cooling. The present invention can convert peripheral far infrared heat energy into useful energy, and this can reduce the consumption of coal gas and natural gas greatly.

The invention provides an EpCAM gene expression detection kit. The kit comprises a capture probe for detecting EpCAM gene mRNA and a signal amplification system; the signal amplification system comprises amplification probes and labeling probes; the capture probes sequentially comprise a specific P1 sequence which can be combined with mRNA of an EpCAM gene to be detected, a solubilizing group anda P2 sequence from the 5' end to the 3' end, the specific P1 sequence, and the specific P1 sequence is a peptide nucleic acid sequence with the length of 16-20 bp; the amplification probes are connected to the capture probe and the labeling probes, and bases of each amplification probe from the 5' end to the 3' end are sequentially composed of a P3 sequence, a spacer arm sequence and a P4 sequencewhich can be complementarily paired with the P2 sequence; and the labeling probes are connected to the amplification probes and fluorophore, each labeling probe has a P5 sequence complementarily paired with the corresponding amplification probe P4, and the tail end of each labeling probe is modified with the fluorophore. Through optimization of the detection probes, the kit has the advantages ofhigh accuracy, short detection time, time saving, labor saving and the like.

The invention discloses a medicine fusion specifically bound with human angiopoietin-2, and also discloses a preparation method of the medicine fusion and a method for treating senile maculopathy, tumors, inflammatory diseases and endometriosis by using the medicine fusion.

The invention relates to an embryo sex interference preparation for sheep. The embryo sex interference preparation is prepared from the following components in parts by mass: 1-3 parts of vitamin B12,1-3 parts of vitamin C, 1-2 parts of gentamicin sulfate, 0.8-2.2 parts of oxytocin and 1-2 parts of glucose liquid. The preparation has the advantages that the activity of Y-chromosome sperms of thesheep can be obviously inhibited, capacitation of X-chromosome sperms can be promoted, the movement of the X-chromosome sperms can be promoted, the activity ability of the X-chromosome sperms can be enhanced, the survival time of the X-chromosome sperms can be prolonged, the combination probability of the X-chromosome sperms with eggs can be increased, and therefore the sex of embryos can be interfered and influenced, and finally the effect of improving the proportion of female lambs can be achieved.