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36results about How to "Promotes mitosis" patented technology

Whitening essence containing siRNA (Small Interfering Ribose Nucleic Acid) cell culture for inhibiting generation of melanin

The invention discloses a whitening essence containing an siRNA (Small Interfering Ribose Nucleic Acid) cell culture for inhibiting generation of melanin. The whitening essence is prepared from an epidermal cell culture fluid, contains the siRNA used for inhibiting the expression of tyrosinase (Tyr) and is used for interdicting the generation of the melanin in skin tissue melanin cells. With the adoption of the whitening essence, the siRNA is coated by lipidosome, enters a skin and is used for exerting the gene inhibition action; and as the epidermal cell culture fluid is rich in growth factors, amino acid and vitamins excreted by epidermal cells, and cell growth factors with a definite content, glycerinum and hyaluronic acid are added, the moisturizing effect of the whitening essence is added. A method of preparing the whitening essence comprises the steps: designing a synthetic siRNA aiming at a tyr gene, preparing an siRNA-lipidosome compound, acquiring an umbilical cord tissue epidermis of a newborn, collecting the cell culture fluid, filtering, concentrating and adding an active component. The whitening essence is used for interdicting the generation of the melanin from the molecular level, provides multiple endogenous nutritional ingredients with the physiological activity for the skin and has the moisturizing effect.
Owner:奥思达干细胞有限公司

Treatment method of paddy rice seeds

The invention belongs to the technical field of paddy rice planting and particularly relates to a treatment method of paddy rice seeds. The method comprises the following specific steps: firstly, selecting paddy rice seeds with full grains, no worm stings and no mildew or rot, carrying out vapor treatment, taking out the seeds, then immersing the seeds into an acetic acid solution, continuously stirring a mixed solution by a stirrer and taking out filtrate; secondly, putting the paddy rice seeds into a drying baker for drying until the moisture content is 7 to 9 percent, taking out and immersing the paddy rice seeds into a seed soaking agent for soaking, and then introducing ultrasonic waves for carrying out ultrasonic treatment; fishing out a filter reagent, carrying out constant-temperature freezing and taking out; thirdly, carrying out vacuum treatment and microwave drying until the moisture content is 14 to 18 percent. The treatment method of the paddy rice seeds has the advantagesthat the tissue protection ability of the paddy rice seeds is favorably improved, membrane repair is promoted and the sensitivity of a cell membrane to drought stress during development is reduced; in addition, the metabolism intensity of paddy rice cells can be effectively enhanced, the growth of radical buds is promoted and the transport efficiency of materials is improved; besides, the germination rate of the seeds is improved, and the resistance of young seedlings is improved, so that high germination speed, high uniformity and good growth vigor are realized.
Owner:孙立成

Primary mouse liver cancer model based on liver oval cell malignancy as well as establishment method and application of primary mouse liver cancer model

The invention relates to the technical field of cancer animal model establishment, in particular to a primary mouse liver cancer model based on liver oval cell malignancy and an establishment method and an application thereof. The establishment method comprises the following steps: transforming liver oval cells by using a proto-oncogene to obtain liver cancer stem cells; performing in-situ transplantation on the liver cancer stem cells to the liver of a receptor mouse to obtain a primary mouse liver cancer model; wherein the acceptor mouse is a wild type mouse subjected to X-ray irradiation treatment. According to the scheme, aiming at the limitation of the existing primary liver cancer animal model, a novel primary model for simulating the whole occurrence and development natural process of the primary liver cancer is established, so that the effect and mechanism of a specific gene in the occurrence and development of the primary liver cancer can be accurately researched, and whether the gene can be used as an effective treatment target or not is verified. By utilizing the model in the scheme, potential new targets and new drugs for treating the primary liver cancer can be screened, and conditions are created for researching and developing novel drugs or treatment methods for treating the primary liver cancer.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

Pumpkin flower natural polypeptide preparation method and application

The invention provides a pumpkin flower natural polypeptide preparation method. The preparation method comprises the steps of completely washing pumpkin flowers and performing dicing, performing homogenizing at a low temperature, performing standing for 12h at a low temperature, carrying out gel chromatography separation purification on a centrifuged supernatant extracting solution, and collectinga part with the molecular weight of 500-12000 Daltons, namely the pumpkin flower natural polypeptide, and carrying out vacuum freeze drying on the part of natural polypeptide collection solution, soas to obtain pumpkin flower natural polypeptide powder. The pumpkin flower natural polypeptide prepared by the preparation method provided by the invention is relatively low in molecular weight, retains relatively high natural activity and can be used for preparing health-care foods and foods.
Owner:北京中科卓明生物医学研究所有限公司

Traditional Chinese medical healthcare dispersible tablet for treatment of rhinitiss and preparation method thereof

The invention discloses a traditional Chinese medical healthcare dispersible tablet for treatment of rhinitiss and a preparation method thereof. The traditional Chinese medical healthcare dispersible tablet comprises the following raw components by weight ratio: 25 parts of raw astragalus mongholicus, 10 parts of codonopsis pilosula, 6 parts of radix saposhnikoviae, 10 parts of fried rhizoma atractylodis, 10 parts of radix bupleuri, 10 parts of schisandra chinensis, 10 parts of prepared liquorice and 10 parts of magnolia flower. Dry paste powder is prepared with the eight herbal materials. The weight ratios of the dry paste powder and raw additives are as follows: 51.8 parts of dry paste powder, 10 parts of sodium carboxymethyl starch, 13.2 parts of cross-linked povidone, 24 parts of microcrystalline cellulose, 0.5 part of magnesium stearate, 0.5 part of superfine silica powder and 50 parts of ethanol. Compared with the existing products with relevant effects in the market, the traditional Chinese medical healthcare dispersible tablet has the advantages of low dosage, convenience in taking, rapid absorption, high bioavailability, convenience in carrying, accurate quantification, stable quality, no adverse reactions, no medicine resistance and the like.
Owner:XIAN FUAN INNOVATION CONSULTATION

Kidney-tonifying, blood-nourishing and anti-aging ginseng-grass formula

The invention discloses a kidney-tonifying, blood-nourishing and anti-aging ginseng-grass formula, and relates to the technical field of health-preserving and health-care products, and the formula of the ginseng-grass formula comprises the following components: 16% of donkey-hide gelatin; 23% of ginseng; 12-18% of cordyceps militaris; 4-8% of wolfberry; 10 to 14% of raspberry; 5-9% of longan; 6-10% of mulberry; 3-7% of poria cocos; 3-6% of ginger; and 3% of old brown sugar. The medicinal liquor prepared by the ginseng-grass formula under the seasoning and antibacterial effects of the brown sugar and the fresh ginger is suitable for women with qi deficiency, blood stasis, yang deficiency and yin deficiency, and also can be used for treating kidney deficiency (yin deficiency and yang deficiency) and qi deficiency of males, so that the effects of tonifying qi and kidney, regulating yin and yang and balancing the kidney hormone level are realized. In the aspect of kidney tonifying, kidney tonifying, qi benefiting, endocrine improving, hormone level balancing and senescence delaying are achieved; blood replenishing effect of soothing liver and regulating qi, warming kidney and tonifying spleen is realized, and realizing full nourishing of blood to visceral organs; and the effect of supplementing qi is realized on the basis of preventing angiosclerosis, the invention can also promote blood circulation to remove meridian obstruction and improve blood circulation.
Owner:上海中药创新成果转化中心有限公司

Composite radix puerariae blocks and preparation method thereof

InactiveCN107568549AAvoid churnEffectively retains active ingredientsFood scienceVitamin CBlock structure
The invention provides composite radix puerariae blocks and a preparation method thereof. The composite radix puerariae blocks comprise the following raw materials in percentage: 20-40% of fresh radixpuerariae, 20-40% of fresh yam beans, 10-30% of fresh sugarcanes, 0.5-3% of fresh ginger, 10-20% of protein powder, 1-5% of vitamin C, 0.01-0.22% of tea polyphenols and 0.000001-0.0022% of vitamin B.The beverage of the composite radix puerariae blocks is obtained through pretreating the raw materials, sequentially performing procooling, performing quick-freezing, performing sublimation drying and performing resolution drying. The product adopts a solid block structure of which the water content is smaller than or equal to 9%, so that the product is convenient to store and transport. Practiceproves that the composite radix puerariae blocks have excellent efficacy of neutralizing the effect of alcoholic drinks and protecting the liver, have the advantages of being delighted in mouth feeland convenient to take, facilitate mass production and market promotion, and have good market benefits.
Owner:四川江茂食品有限公司

Human adipose tissue-derived stromal cell culture medium and preparation method thereof

The invention discloses a human adipose tissue-derived stem cell culture medium. The culture medium is composed of a basic culture medium and additives, wherein the additives are prepared from 3-6 ng/mL of sennoside, 5-10 ng/mL of parsnip lactone, 1-4 ng/mL of wheat seedling powder, 12-15 ng/mL of hydroxypropyl beta-cyclodextrin, 5-8 micrograms/mL of sodium pyruvate, 20-25 micrograms/mL of glutathione and 0.5-1 microgram/mL of chlorogenic acid. According to the human adipose tissue-derived stem cell culture medium provided by the invention, the sennoside and the parsnip lactone are added, so that the metabolic activity of human adipose tissue-derived stem cells can be improved, cell mitosis can be promoted, the aging and apoptosis of the cells can be delayed, and the proliferation capacity of the cells can be improved. By adding the wheat seedling powder, molecular garbage in the cells can be reduced, mitochondria can be protected, and the activity of telomerase can be better maintained. The hydroxypropyl beta-cyclodextrin, the sodium pyruvate, the glutathione and the chlorogenic acid can be used for providing a stable external environment for cell proliferation, and the sodium pyruvate and the glutathione have relatively good oxidation resistance and are used for helping in maintaining stability of a cell membrane structure. The chlorogenic acid is beneficial to keeping the sterility of the culture medium.
Owner:爱克精医(长春)生物医药科技有限公司

Multi-effect bactericidal composition containing organosilicon plant growth regulator

The invention discloses a multi-effect bactericidal composition containing an organic silicon plant growth regulator, and relates to the technical field of agriculture. The composition is mainly designed for solving the problem that bactericides sold on the market at present can generate drug resistance after long-term use of plants and the like. The composition comprises a component A, a component B and a component C, the component A and the component B are active components capable of playing a role in plant growth regulation, and the component C is an auxiliary agent. The active component Aaccounts for 0.01%-90% of the mass of the composition, the active component B accounts for 0.001%-90% of the mass of the composition, and the active component A is silicon abundance ring. The activecomponent B is one or more of tricyclazole, tebuconazole, metalaxyl, hymexazol, pyraclostrobin and prochloraz, and the auxiliary agent is any one dosage form permitted in pesticide prepared from a conventional surfactant, a solvent, a cosolvent or a solid filler permitted in pesticide preparation. The composition has the advantages that the same resistance does not exist, and the resistance problem caused by single use of two single agents can be delayed.
Owner:辽宁山水益农科技有限公司

Contains siRNA cell culture whitening essence that inhibits melanin production

The invention discloses a whitening essence containing an siRNA (Small Interfering Ribose Nucleic Acid) cell culture for inhibiting generation of melanin. The whitening essence is prepared from an epidermal cell culture fluid, contains the siRNA used for inhibiting the expression of tyrosinase (Tyr) and is used for interdicting the generation of the melanin in skin tissue melanin cells. With the adoption of the whitening essence, the siRNA is coated by lipidosome, enters a skin and is used for exerting the gene inhibition action; and as the epidermal cell culture fluid is rich in growth factors, amino acid and vitamins excreted by epidermal cells, and cell growth factors with a definite content, glycerinum and hyaluronic acid are added, the moisturizing effect of the whitening essence is added. A method of preparing the whitening essence comprises the steps: designing a synthetic siRNA aiming at a tyr gene, preparing an siRNA-lipidosome compound, acquiring an umbilical cord tissue epidermis of a newborn, collecting the cell culture fluid, filtering, concentrating and adding an active component. The whitening essence is used for interdicting the generation of the melanin from the molecular level, provides multiple endogenous nutritional ingredients with the physiological activity for the skin and has the moisturizing effect.
Owner:奥思达干细胞有限公司
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