The invention provides a method and device for refining 2,2-methoxy propane. The method includes the steps of S1, primarily separating a feed solution containing 2,2-dimethoxy propane, methyl alcohol, acetone and water via a azeotrope tower, and allowing part of azeotrope of acetone and methyl alcohol which are extracted from the top of the tower to the azeotrope tower; S2, leading materials extracted from the bottom of the azeotrope tower to an extractive rectification tower for rectification, leading the materials extracted from the top of the extractive rectification tower to a stratified tank, and leading the material extracted from the bottom of the extractive rectification tower to a methanol tower; S3, leading part of water from the bottom of the methanol tower to the stratified tank to serve as an extraction agent for recycling use, leading water phase in the stratified tank into the extractive rectification tower as backflow, and leading oil phase into a product tower; S4, obtaining the 2,2-dimethoxy propane from the bottom of the product tower. The method is low in energy consumption, and 2,2-dimethoxy propane products with mass fraction of more than 99.5% can be obtained.