8 results about "O methylglucose" patented technology

A composition comprising: i) from 2% to 5% by weight of an aqueous solution comprising a hydrophilic active ingredient; ii) from 1% to 2% by weight of methyl glucose sesquistearate; iii) from 10% to 12% by weight of a polyglycerol-3 ester of a fatty acid; iv) at least 83% by weight of an ester oil selected from the group consisting of cetyl ethylhexanoate, isopropyl isostearate, and ethylhexyl palmitate; and wherein all weight percentages are based on the total weight of the composition; and wherein the sum of i), ii), iii) and iv) does not exceed 100% by weight. A method for dispersing a hydrophilic active ingredient in an oil. A cosmetic or dermatological pharmaceutical formulation comprising the initial composition. The invention also relates to a cosmetic or dermatological pharmaceutical formulation. A method of cosmetic, non-therapeutic treatment and / or care of skin, hair, nails and / or mucous membranes of a subject comprising topical application of a cosmetically effective amount of the composition.

The application belongs to the technical field of medicine production, and particularly relates to a preparation method and application of five deuterium-substituted glucose. The method comprises deuterium substitution of D-methyl glucoside, and demethylation of the deuterium-substituted D-methyl glucoside to obtain a target product, namely [2,3,4,6,6'-d5]-D-glucose. The preparation method of the five deuterium-substituted glucose is simple in process route, convenient to operate, mild in experimental conditions, and the synthesized five deuterium-substituted glucose is successfully applied to the description of glycolysis metabolism in a brain glioma model, which is helpful to the clinical conversion application of metabolic imaging technology.

This invention discloses a UiO-66 composite material co-modified with polyethyleneimine and N-methyl-D-glucosamine, and its preparation method, belonging to the field of porous adsorption materials technology. This invention employs a two-step modification strategy. First, polyethyleneimine (PEI) is impregnated with the metal nodes of UiO-66 surface-modified with γ-aminopropyltriethoxysilane (KH550) to form a high-amine-density intermediate layer on its surface. Then, the abundant amino groups on PEI undergo a nucleophilic substitution reaction with Cl-NMDG generated from the ring-opening reaction of N-methyl-D-glucosamine (NMDG) via cyclochloropropane (ECH), grafting NMDG onto the PEI-modified UiO-66, thereby preparing the PEI and NMDG co-modified UiO-66 composite adsorbent UiO-66 / PEI@NMDG. While maintaining the high specific surface area and stability of UiO-66, a novel boron removal adsorption material with high adsorption capacity, fast kinetics and high selectivity was developed by introducing multiple hydroxyl recognition sites at a high density.

The present invention belongs to the field of cosmetology and relates to a cosmetic product with a low pilling effect. In particular, the cosmetic composition of the present invention comprises a) at least one polyglycerol having 2 to 20 subunits, and b) a polyglyceryl-3 methyl glucose distearate, the present invention relates to a polymer composition, but which does not contain 1) a polymer polymerized from a mixture comprising or consisting of acrylic acid, methacrylic acid and / or vinyl pyrrolidone, 2) a silicone oil, and 3) a polyethylene glycol derivative.

Provided is a Hydrogenophilus bacterium mutant in which at least one of the below-mentioned enzyme genes (a) to (d) is disrupted, wherein the enzyme genes are located on the chromosome of a Hydrogenophilus bacterium and catalyze any one of reactions in the pathway for generating 3-hydroxybutyryl-CoA from crotonyl-CoA. The mutant is improved in terms of crotonyl-CoA production capability and can therefore be used for the efficient production of useful substances generated via crotonyl-CoA. (a) A gene that encodes a polypeptide having a 3-hydroxybutyryl-CoA dehydratase activity; (b) a gene that encodes a polypeptide having an enoyl-CoA hydratase activity; (c) a gene that encodes a polypeptide having a 3-hydroxyacyl-CoA dehydrogenase activity; and (d) a gene that encodes a polypeptide having a methylglutaconyl-CoA hydratase activity.

The application belongs to the technical field of oil wells, and provides a high-temperature-resistant oil well cement retarder and a preparation method thereof.The raw materials of the high-temperature-resistant oil well cement retarder include sulfonated 5,6-diamino-1,10-phenanthroline, sodium methyl gluconate, modified palmitamide, inorganic salt, sodium p-styrenesulfonate and water.The preparation method includes the following steps: adding the raw materials into a reaction kettle in steps, stirring at constant temperature, and cooling to room temperature to obtain the high-temperature-resistant oil well cement retarder.The retarder can solve the problems of existing retarders, such as high-temperature complexing capacity attenuation, low thickening time control precision and insufficient compressive strength, realize efficient retarding at 200 DEG C, and simultaneously improve the construction stability and the mechanical properties of cement stone.The preparation process is simple, the raw materials are easy to obtain, the retarder can be adapted to different well depth and high-temperature cementing requirements, and has high practicability.

The application provides a boron removal method of moxifloxacin hydrochloride and a preparation method of pure moxifloxacin hydrochloride, and belongs to the technical field of medicine preparation. In the application, LSC-800 resin is used for adsorbing and removing boric acid under the condition that the pH value is 8-9. The LSC-800 resin is a macroporous structure chelating resin which is crosslinked by styrene and divinylbenzene and has N-methylglucosamine groups. The polyol group part of the LSC-800 resin can generate complex anions with boric acid groups, and the amine group part of the LSC-800 resin can capture the generated complex anions as anion exchange groups, so that the boric acid ions in the boric acid-containing moxifloxacin hydrochloride can be selectively adsorbed, and the boric acid ions can be effectively removed. The results of the examples show that no boric acid is detected in the obtained moxifloxacin hydrochloride by using the boron removal method.

A composition comprising: i) 2-5% by weight of an aqueous solution containing a hydrophilic active ingredient; ii) 1-2% by weight of methyl glucose sesquistearate; iii) 10-12% by weight of a polyglyceryl-3 ester of a fatty acid; and iv) at least 83% by weight of an ester oil selected from the group consisting of cetyl ethylhexanoate, isopropyl isostearate, and ethylhexyl palmitate, all weight percentages being based on the total weight of the composition, and the sum of i), ii), iii), and iv) not exceeding 100% by weight. A method for dispersing a hydrophilic active ingredient in an oil. A cosmetic or dermopharmaceutical formulation comprising the initial composition. A method for cosmetic, non-therapeutic treatment and / or care of the skin, hair, nails, and / or mucous membranes of a subject, the method comprising topically administering a cosmetically effective amount of the composition.