201 results about "Pilot plant" patented technology

This invention fills several voids in bioreactor technology that allows efficient connection of aspects of physical science (optics, electronics, physical chemistry, sensors) to aspects of microbial and cell culture physiology in a uniquely interactive manner. This is accomplished mathematically through decision making software that utilizes detected changes in the course of fermentation. Decisions are aimed at determining the optima for cellular growth, optimizing for production or degradation of metabolites or substrates, or determining the limits of growth under various combinations of conditions. The invention determines optima or limits in a manner more quickly and at less cost than traditional methods. The basis for the computer generated decisions may be first or second derivative changes observed such as inflection points, limits on allowable rates of change, or the like. The most common measured parameter controlling the decision making process is the optically observed growth of the cells (e.g. microbial, animal, or plant cell cultures) under study. Any other measurable parameter (e.g. pH, temperature, pigment production) may be used to control the process (i.e., the independent variable). This process and variations of this process on a laboratory scale are valuable for research and development, education, pilot plant models, and bio-manufacturing optimization, including scale up to production volumes.

The invention discloses a liquid fermentation method for producing natto kinase in high yield, which comprises a fermentation formula and fermentation conditions. In the method, a natto solid fermentation high-yield strain is selected and subjected to mutation and domestication so as to screen a high-yield strain of natto kinase; and the high-yield strain is inoculated into a liquid nutrient medium for fermentation, wherein the enzyme activity can reach 1,400IU / mL under liquid fermentation of a shake flask. Enzymatic hydrolysate of bean pulp is adopted as a nitrogen source of pilot plant test fermentation, and in a 10L fermentation tank, the fermentation unit can reach 2,650IU / mL. Due to the technical scheme, the yield of the prepared fermentation product natto kinase is high, the enzyme activity is high, the raw materials are saved, the energy is saved, the used raw materials are convenient to obtain and rich, the cost is low, and the extraction technology is easy and practicable.

The invention discloses a preparation method of a nanometer zinc oxide composite dispersion liquid. The method is characterized by comprising the following steps: mixing an oil phase component and an emulsifier according to certain proportion in an oil phase system; adding a dispersion stabilizing agent, a surfactant and a nano zinc oxide powder according to a certain ratio into water in a water dispersion system; and respectively uniformly mixing the two phases and heating to a certain temperature, rapidly stirring the two phases for homogeneous mixing, and cooling to room temperature to form a stable emulsion dispersion system. The nanometer zinc oxide composite dispersion liquid prepared by the above method, the particle size difference of zinc oxide particle and nano zinc oxide powder raw material is within 20%; in the dispersion liquid, nano zinc oxide particles are suspended in the liquid in a monodispersed form; and placing for more than 60 days, the nano zinc oxide composite dispersion liquid does not generate the phenomena of layering, demulsification or caking. Moreover, the preparation method has the advantages of simple operation, wide adjustable range of parameters, low energy consumption and short cycle, and is suitable for pilot plant test amplification and industrial large-scale production.

The invention discloses a method for simulating steel board cooling control. A process control device is connected with a cooling apparatus simulating device by a PLC. The cooling apparatus simulatingdevice comprises a transmission device on which a steel bar is fixed, a cooling process temperature calculating device for simulating temperature measurement, a polling display instrument for displaying temperature, an electric potentiometer, a photoelectric switch and a position indicator. The photoelectric switch is arranged on a movement path of the steel bar. The process control device accomplishes the optimum setting of PLC control amount. The PLC accomplishes real-time control of a cooling simulating process. The cooling apparatus simulating device actually opens or closes and adjusts asimulating cooling line and realizes real-time data acquisition. Through the hardware mutual connection and software cooperation of the devices, the simulation on a cooling control process system isaccomplished. The invention provides a pilot plant test device of simulation evaluation for the improvement and completion of the control system.

The invention relates to a high-voltage electrostatic shuttle nano spinning device, which consists of a box, a storage tank, a valve, an electrostatic shuttle, a supply pipe, a return pipe, an overflow material recycling tank, an electric thermostat, a metal bracket, a receiving device, a receiving substrate and a high-voltage electrostatic generator, wherein the electrostatic shuttle comprises a shuttle sleeve and a shuttle core; and the shuttle core consists of a liquid storage cavity, an electrostatic shuttle mouth and a metal high-voltage electrode. The electrostatic shuttle is arranged, so that an enclosed spinning system is formed and a solvent is prevented from volatilizing; in the presence of the electric thermostat, the system is not influenced by the environment (temperature / humidity); the size of the shutter core and voltage can be adjusted, so that the diameter of nanofiber is adjustable and the breadth of a non-woven fabric can be selected optionally; moreover, due to the adoption of differential-pressure material supply and insert assembly, the electrostatic shutter mouth spinning device has the advantages of low energy consumption, low cost and environmental friendliness, is easy to clean, is safe and reliable, is easy and convenient to operate, and the like. A plurality of electrostatic shuttle mouths are connected in series and in parallel. The high-voltage electrostatic shuttle nano spinning device can be applied to laboratories, pilot plant tests and industrial production.

The invention discloses an energetic polyoxide compound super-thermite. The energetic polyoxide compound super-thermite has the chemical formula represented by n-Al / Ax1Oy1.Bx2Oy2 or n-Al / Ax1Oy1.Bx2Oy2.Cx3Oy3, wherein n represents nanometer super-thermite, Ax1Oy1, Bx2Oy2 and Cx3Oy3 are different metal oxides, A, B and C are selected from Group II, III, IV and V main group metal elements, transition metal elements or lanthanide elements, x and y are positive integers and meet chemically reasonable values and the particle size of nanometer aluminum powder is 20-100nm. The energetic polyoxide compound super-thermite is prepared by virtue of a room-temperature solid-phase reaction-ultrasonic oscillation composite method which has the advantages of being low in cost, high in yield, simple and feasible in preparation process, environment friendly, free of pollution and the like and is suitable for pilot-plant-scale and large-scale popularization and production. The compound super-thermite as a combustion catalyst, which is prepared by the method has excellent catalytic effect on the combustion of a double-base propellant and is an efficient combustion catalyst.

The invention discloses a preparation method of a polysubstituted pyrrole compound. The preparation method comprises steps as follows: an alkyne enamine compound is subjected to a cyclization reactionunder the catalytic action of univalent gold, a product is subjected to column chromatography or recrystallization separation, and a fully substituted pyrrole compound is obtained; substituent groupscan be removed from the pyrrole compound under the proper condition, and a tetra-substituted pyrrole compound is obtained. The chain-like alkyne enamine compound is subjected to the cyclization reaction, and the fully substituted or tetra-substituted pyrrole compound is obtained. The preparation method has the advantages that the operation is simple, steps are simple, the reaction is efficient, raw materials are cheap and easy to obtain, the pilot plant test can be amplified and the like.

The invention discloses a technology process for preparing active components of chlorella through scale classification. The technology process comprises the steps of preprocessing raw materials, breaking walls for extracting, dissolving lipid, concentrating chlorella oil, drying chlorophyll, extracting growth factors of chlorella and preparing hydrolyzed protein peptide. According to the technology process, products such as coarse chlorella oil, chlorophyll crude product, growth factors of chlorella and hydrolyzed protein peptide are prepared through classification; the technology process is applicable to processing and production of the chlorella higher than pilot plant test level, even kilogram level small batch production and larger scale production. Through the technology process, various functional components of the chlorella are prepared step by step; the obtained components can be further processed, refined and used for developing downstream products so as to realize maximum value of the chlorella; reagents used in the technology process is innocuous and unpoisonous and low in cost; main solvents can be recycled and reused. In addition, the technology process is low in equipment requirement; the production requirement can be met by using normal plant extraction devices; the technology process is short in extraction time, high in efficiency and low in energy consumption.

The invention provides a millimeter channel type continuous preparation system which can be used in preparation of various inorganic nonmetal nanocrystallines (such as oxides and sulfides). Compared with the prior art, the system has the advantages that 1, a millimeter channel type reaction pipe is adopted, and is internally provided with inner threads, so that turbulent flows are promoted to be generated in the channel, and heat and mass transfer is promoted effectively in the channel; 2, an ultrafiltration purification device is adopted for filtering out raw material molecules or ions which are subjected to non-complete reaction in a reaction mixed liquid, so that the continuous preparation of products is realized; 3, if a material tank is improved further, nitrogen can be introduced, so that the materials can be isolated from oxygen at the normal temperature, and channel type heat reaction is realized under an inert atmosphere. The millimeter channel type continuous preparation system can be used for the pilot plant test preparation of the nanocrystallines and high-molecular polymers, and can be used for effectively controlling the sizes or the molecular weight distribution of the materials.