77 results about "Potassium periodate" patented technology

The invention discloses a thickened oil well polymer plugging remover. The plugging remover is prepared from the following materials in percentage by mass: 0.5 to 5.0 percent of gel breaker, 1.0 to 10.0 percent of cleaning agent, 0.1 to 5.0 percent of clay stabilizer, 0.1 to 5.0 percent of iron ion stabilizer, 0.1 to 5.0 percent of surfactant, 0.1 to 5.0 percent of corrosion inhibitor, 0.1 to 5.0 percent of bactericide and the balance of water, wherein the gel breaker is prepared from 30 to 70 percent of gel breaker I and 30 to 70 percent of gel breaker II, the gel breaker I is one or more of ammonium persulfate, sodium thiosulfate, potassium periodate and potassium monopersulfate, and the gel breaker II is one or more of calcium peroxide, potassium peroxodisulfate, sodium periodate and iron sulfide. The thickened oil well polymer plugging remover is suitable for solving the plugging problem caused by a thickened oil well polymer, has a better plugging removal effect than a conventional single oxidizer or single acid liquor, and has the advantages of good plugging removal effect, strong corrosion resistance, long period of validity, safety and the like.

The invented product includes packaged bag, test paper and color grade. There is an opening in mid part of the packaged bag, and pasted handle is in back of the bag. test paper is saturated by developer mixed from 4- amido-3- hydrazino-5-thiol group-1, 2, 4- triazole solution, potassium hydroxide solution and potassium periodate. color grade marks concentration values, and allowed maximum concentration value issued in national standard. Color of test paper is changed caused by formaldehyde in air. Features are: simple, safe, sensitive, and accuracy.

The formaldehyde rapid detection device and the manufacturing method thereof of the present invention belong to the technical field of toxic substance detection. The composition of the formaldehyde rapid detection device includes a test paper sheet, a color developer and a color scale card; the test paper sheet is a white test paper that is soaked in an aqueous solution composed of sodium hydroxide and potassium periodate and taken out to dry, and the color developer is 4-amino- The solution obtained by dissolving 3-hydrazine-5-mercapto-1,2,4-triazole in hydrochloric acid; the test paper piece (1) can be installed in the test paper piece positioner (2) with a hole on the front and a groove on the back Inside, the groove is fastened with the back cover (4); a white bottom plate (3) is installed between the test paper sheet (1) and the back cover (4). The invention is simple in structure, sensitive in detection, low in price, convenient and safe to use, has the characteristics of simplicity, quickness, intuition, accuracy, practicality, and can be used by all kinds of people by themselves, and is suitable for on-site detection of formaldehyde content in food, water quality and air.

The invention relates to a multifunctional cationic polymer gene vector and a preparation method and application thereof. A multifunctional cationic polymer is synthesized by oxidizing low molecular weight chitosan used as a framework material with potassium periodate and subjecting the oxidized low molecular weight chitosan and polyethyleneimine coupled with a sartan-class drug to reduction and ammonification. To overcome technical problems, the invention provides the novel cationic polymer with targeting performance of the acceptor of the tumor cell AT1, multiple proton buffering capability and adjuvant therapy effects on tumors and provides a preparation method with the advantages of mild conditions, low cost, applicability and reliability for the cationic polymer. A compound formed by the cationic polymer provided by the invention and plasmid DNA has the advantages of low cytotoxicity, good targeting performance, high transfection efficiency, substantial in-vitro antineoplastic effects, etc.; the polymer can be used for preparation of a non-virus gene transfer system capable of simultaneously transferring a gene drug and a chemical drug for cooperated treatment of a tumor.

The invention discloses a compact imporous wood coating which is prepared from the following raw materials in parts by weight: 10-14 parts of aluminium-magnesium silicate, 70-100 parts of natural latex, 560-600 parts of an acrylic emulsion, 3-4 parts of triammonium molybdate, 2-3 parts of mannitol, 1-2 parts of butyl benzyl phthalate, 2-3 parts of sodium pyrophosphate, 0.1-0.13 part of potassium periodate, 1-2 parts of sodium acetate, 7-10 parts of chitosan, 24-30 parts of polyvinyl alcohol, 0.1-0.2 part of nano alpha-Fe2O3, 1.3-2 parts of polyglycerol fatty acid ester, 2-3 parts of sericin, 5-7 parts of beewax, 140-160 parts of titanium dioxide, 2-3 parts of polyoxyethylene ether, 1-2 parts of trimethylethoxylethylenediamine and 0.6-1 part of alkyl succinic acid. The coating disclosed by the invention is good in compactness, has no shrinkage cavities on the surface, and is free of deposition, smooth and good in leveling property.

The invention belongs to the technical field of microelectronic processes, particularly discloses a polishing solution used in a polishing process with metal ruthenium as an adhesive barrier layer in copper interconnection. The polishing solution comprises the following component raw materials by weight: 0.001 to 10 percent of an inhibitor, 0.1 to 10 percent of an oxidant, 1 to 25 percent of grinding particles, 0.001 to 5 percent of a surfactant, and the balance of water. After the raw materials are mixed, the pH value is regulated to 8.5 to 9.5 through a pH regulator; the inhibitor is selected from organic acid with one or more amino groups and carboxyl groups at the same time, and the oxidant is selected from hydrogen peroxide, ammonium persulphate, potassium periodate, potassium bromate, perborate ammonium ceric nitrate and the like; and the grinding particles are selected from SiO2 hydrosol or hydrosol of metal oxide Al2O3, CeO2 or TiO2 and the like. The polishing solution disclosed by the invention shows weak alkaline, does not corrode and contaminate equipment, is easy to clean, and can polish ruthenium (Ru) and cuprum (Cu) at a polishing selection ratio of 1:1, and the smoothness is good after polishing.

The invention relates to a rapid measurement reagent for manganese concentration in water and a use method thereof. The rapid measurement reagent for the manganese concentration in water comprises a reagent A and a reagent B in a mass ratio of 1:1, wherein (1) the reagent A comprises the following components in percentage by weight: 5.0-15.0 anhydrous potassium pyrophosphate, 10.0-30.0 disodium hydrogen phosphate, 0.5-5.0 citric acid and 60-80 anhydrous sodium sulphate; (2) the reagent B comprises the following components in percentage by weight: 5-25 potassium periodate and 75-95 potassium chloride. The use method of the rapid measurement reagent comprises the following steps: adding the reagent A to a water sample to be measured, adding the reagent B after the reagent A is dissolved; standing for 10 minutes; and comparing colors with a standard colorimetric card, a colorimetric disc or a colorimetric meter, and reading the manganese concentration. The invention has the advantages ofsimple and convenient operation, accurate results, low price, convenient transportation and carrying, on-site measurement suitability, and the like.

The invention discloses a method for detecting ferritin based on nanogold catalytic chemiluminescence analysis. The method comprises the following steps that 1), a nanogold solution is prepared, 0.01% w / w of a HAuC14 solution of is heated to boiling, a sodium citrate solution of 1% is added under hard stirring, a heating source is removed after the mixed solution keeps boiling for fifteen minutes, the mixed solution is continuously stirred and cooled to the room temperature, and the obtained solution is stored in a refrigerator with the temperature of 4 DEG C for standby application; 2) nanogold is marked through ferritin antibodies, and the ferritin antibodies are utilized for modifying nanogold particles; 3), immunoreaction is carried out; 4), ferritin is detected through the chemiluminescence analysis, a nonogold / ferritin mixed solution modified by the ferritin antibodies after the immunoreaction is finished is moved into a chemiluminescence pool, a luminol-potassium periodate chemiluminescence reagent is injected into the solution, and the chemiluminescence intensity of the solution is measured and recorded through an IFFL-D chemiluminescencent analyzer to obtain the correlation between the chemiluminescence intensity and the ferritin to be measured.

The invention belongs to the technical field of adsorbing materials, and discloses an ion-imprinted nanocellulose adsorbing material and a preparation method and application thereof. The preparation method comprises the following steps of conducting oxidation modification with potassium periodate, amination modification with ethylenediamine, and thiocarbamide modification with potassium thiocyanate on nanocellulose successively, adding an imprinting metal ion solution and a formaldehyde solution, conducting a cross-linking polymerization reaction with stirring, immersing the polymerization products into an acid solution to remove imprinting metal ions, and obtaining the ion-imprinted nanocellulose adsorbing material. The ion-imprinted nanocellulose adsorbing material has high adsorbability and selectivity for metal ions, and can be used for removing and recycling metal ions, such as mercury ions, lead ions and copper ions.

The invention discloses a method for modifying biochar. The method comprises the following steps: 1) carrying out oxygen-limited pyrolysis on wheat straws and fresh whole-plant Typha orientalis into biochar, and crushing the biochar; 2) immersing the prepared biochar in hydrogen peroxide first, then immersing the biochar in an aqueous solution of maleic acid and polyethylene glycol, and cooling and filtering the obtained solution to obtain a solid phase A; 3) dispersing the solid phase A in ethanol to form a suspension, and adding 2,2,6,6-tetramethylpiperidine-nitrogen-oxide and methacrylic acid to the suspension in order to obtain a solid phase B; 4) immersing the solid phase B in an aqueous solution of acetic acid, and adding potassium periodate to the obtained solution in order to obtain a solid phase C; and 5) immersing the solid phase C in a mixed solution of dimethylformamide and N-methylpyrrolidone in order to obtain modified biochar. The modification process of the biochar is optimized, the wheat straws and the Typha orientalis are used as the composite biochar, and the composite biochar is optimized and modified, so the modified biochar has a very significant Cd repairingeffect, and significantly reduces the toxicity of heavy metals in soil after being applied to the cadmium contaminated soil.

The invention relates to the field of medical image diagnosis and provides a preparation method and the application of macromolecule encapsulation magnetic nano-particle contrast agent. The current preparation method of superparamagnetic contrast agent is complex. The preparation of the macromolecule encapsulation magnetic nano-particle contrast agent comprises the steps as follows: iron chloride, iron dichloride and glucan are dissolved in secondary distilled water; strong ammonia is added slowly at the temperature of 15 DEG C to 40 DEG C to be constantly stirred for 130 to 150 minutes; centrifugal separation and deposition are carried out; potassium periodate solution is added; the processed solution is put into borate buffer solution with pH of 8.0; mouse anti-human CA19-9 antibody is added to be reacted at the temperature of 4 DEG C over a night; potassium borohydride is added to be reacted for 5 to 8 hours; and the mixture is purified and separated to be dispersed in buffer solution with pH of 7.4 to obtain the macromolecule encapsulation magnetic nano-particle contrast agent. The invention has the advantages that the invention improves the tumor magnetic resonance imaging contrast with good effect, has simple preparation method and is safe and convenient for use.

The invention provides a preparation and recovery method of 2-methyl-5-iodobenzoic acid. The method comprises the steps: iodinating by using iodine / potassium periodate in a mixed acid solvent and taking otoluic acid as a raw material to obtain a mixture of 2-methyl-5-iodobenzoic acid, 2-methyl-3-iodobenzoic acid and 2-methyl-3, 5-diiodosalicylic acid; refining to obtain 2-methyl-5-iodobenzoic acid and a mother solution regenerant, wherein the mother solution regenerant is the mixture of 2-methyl-5-iodobenzoic acid, 2-methyl-3-iodobenzoic acid and 2-methyl-3, 5-diiodosalicylic acid; recovering otoluic acid and iodine ions through catalytic hydrogenation deiodination; oxidizing the iodine ions for recovering iodine. The whole process is circularly utilized. The preparation and recovery method has the advantages that the raw material is easy to obtain and low in price, the preparation process is simple in operation, the equipment requirement is low, and the method is suitable for large-scale industrial production.

The invention discloses an organic and inorganic composite magnesium alloy non-chromium passivation treatment fluid, pertains to the field of metal materials, and relates to a problem of treatment of metal material surface, and in particular to a passivation treatment fluid which can improve the corrosion resistance of the magnesium alloy surface and does not contain hexavalent chromium. In the method, within the pH value range of 8-10, organic resins such as 10 to 25 percent of waterborne acrylic resin, polyurethane, organic silicon and the like are adopted as a film forming agent; 0.01 to 2 percent of inorganic passivating agent such as ferrate or the like is added; a passivation solution stabilizing agent such as 0 to 5 percent of potassium periodate or the like is added; the method of roll coating, dip coating or the like is adopted for evenly coating the passivation solution on the surface of the magnesium alloy; and then non-chromium passivation film with good corrosion resistance is obtained after curing at the temperature above 80 DEG C. The formed film has 'self-healing' function after the composite passivation solution acts on the surface of the magnesium alloy, thus obtaining passivation film with good corrosion resistance and realizing the preparation of environment-friendly passivation film.

The invention relates to a method for demonstrating a formaldehyde removing effect of a paint film with a formaldehyde removing function. Chemical reaction of the demonstration method is based on an AHMT (4-amino-3-hydrazino-5-mercapto-1, 2, 4-triazol) method for testing formaldehyde. A to-be-tested sample plate is coated with paint with a formaldehyde removing function and paint without a formaldehyde removing function, the paint is oxidized into a purple red compound by potassium periodate through condensation of formaldehyde and AHMT under an alkaline condition after dried, and the formaldehyde content is tested through colorimetric ration. According to the method for demonstrating the formaldehyde removing effect of the paint film with the formaldehyde removing function, the formaldehyde removing effect of the paint film with the formaldehyde removing function can be demonstrated in ten minutes through color change comparison and can be demonstrated to a customer rapidly and directly, the cognition on the paint with the formaldehyde removing function is enhanced further, and marketing demonstration is facilitated.

The invention discloses a detecting tablet for measuring manganese content in water bodies, relating to preparation and application methods of tablets for detecting manganese content in water quality and solid samples. The detecting tablet is prepared from potassium periodate, potassium pyrophosphate, anhydrous sodium acetate, sulfamic acid and citric acid, which are mixed according to a certain proportion and then are subjected to tabletting. When in use, the detecting tablet is directly soaked in a 10mL water sample, the water sample is slightly shook for 5-10 minutes to dissolve the detecting tablet, and the manganese content is measured by a spectrophotometer or a liquid colorimeter. The detecting tablet for measuring manganese content disclosed by the invention is convenient to carry and easy to store, no reagent is added during an application process, and the measurement result is accurate, so that the detecting tablet is suitable for onsite detection on manganese content of solid materials and the water bodies such as surface water, underground water, domestic sewage and industrial wastewater.

The invention discloses a treating method suitable for high-acidity metallurgical-industry wastewater. A composite treatment agent is prepared from polyferric chloride, corn starch, coconut shell charcoal, perlite, potassium periodate, cinnamyl aldehyde, alum, ferric citrate, polyurethane, plant fibers, hydrogen peroxide, benzoin diethyl ether, sodium carboxymethylcellulose, baicalein phosphate and a coagulant aid, the corresponding water treatment technologies including adsorption, treating-agent treatment, anaerobic treatment, photo-catalytic oxidation, sodium hypochlorite oxidation, aeration, electric flocculation, electroflotation and the like are used in cooperation, and the acidity of the treated wastewater is greatly reduced; meanwhile, heavy metal such as lead, arsenic and chromium is effectively removed, the environment-protection requirement of standards can be met, and good application prospects are achieved.

The invention relates to an autoanalysis method of iron content in water samples. In the method, operated at low pressure, an analytical instrument including a sample flow path, a coloration liquid flow path, an oxidation liquid flow path, a promotion liquid flow path, a low pressure pump, an injection valve, an injection loop, an analysis flow path, an optical flow cell, an optical detector and a computer processing system is used. The method includes the steps of: starting the analytical instrument, mapping a sample spectrum, replacing samples S1 by a series of samples S2 with known concentrations of ferrous ions or ferric ions, repeating the mapping step of the sample spectrum to obtain a series of standard spectra, drawing a working curve by taking the concentrations of standard samples as an abscissa and taking peak heights of the standard sample spectra as a vertical coordinate, comparing the drawn test sample spectra with the standard sample spectra, and calculating the iron content of the sample by a regression equation of the working curve. A coloration liquid R is a neutral red-sulfuric acid aqueous solution, an oxidation liquid O is a potassium periodate aqueous solution, and a promotion liquid C is deionized water.

The invention relates to a method for detecting trace manganese in an environmental sample, belonging to the field of a detection method of the environmental sample. The method comprises the steps of weighing 0.200g of environmental sample, and putting the environmental sample into a quartz beaker; feeding 10mL of top-grade pure nitric acid, and carrying out low-temperature decomposition; when the color of organic matter is changed into light yellow from brown, feeding 1mL of perchloric acid into the organic matter, and continuously decomposing until white smoke is not produced and the solution is nearly dry; cooling, and then decomposing by 25mL of 1% nitric acid; then, feeding 1mL of 5% potassium periodate and 2mL of concentrated nitric acid into the solution, heating and boiling; after reddish color appears, carrying out micro-boiling for 3 minutes; adjusting the pH value of the obtained solution to be 3, and pouring the solution into a conical flask, wherein 30mg of cross-linked chitosan (CCTS) which is subjected to cross linking by epichlorohydrin is contained in the conical flask; oscillating for 30 minutes on a constant temperature shaking table, and filtering; eluting the adsorbed CCTS subjected to cross-linking by epichlorohydrin by 10 drops of 10% hydroxylamine hydrochloride, and making up the volume to be 5ml; and measuring the content of manganese by a flame atomic absorption spectrometry. The method is simple, convenient, rapid, high in repeatability and low in detection limit, has an accurate result and has a relatively high practical value when being used for detecting the trace manganese in the environmental sample.

The present invention provides a printing and dyeing wastewater treatment agent and a preparation method thereof, and the printing and dyeing wastewater treatment agent comprises the following components by mass: 60-80 parts of calcium aluminate powder, 10-15 parts of potassium periodate, 5-9 parts of polyacrylamide, 6-8 parts of malic acid, 20-40 parts of bentonite and 30-40 parts of diatomaceous earth. The printing and dyeing wastewater treatment agent is capable of removing heavy metal ions, COD, dyes and other harmful substances in printing and dyeing wastewater, and also has the role of decolorization, deodorization, degreasing and sterilization, the decolorization rate can reach 95% or more, and the printing and dyeing wastewater treatment agent is simple preparation method in and low in cost.

The invention discloses am anti-stripping wood coating which is prepared from the raw materials in parts by weight: 3-4 parts of tertiary butyl p-diphenol, 2-3 parts of sodium pyrophosphate, 0.1-0.13 part of potassium periodate, 1-2 parts of sodium acetate, 7-10 parts of chitosan, 24-30 parts of polyvinyl alcohol, 0.1-0.2 part of nano alpha-Fe2O3, 1.3-2 parts of polyglycerol fatty acid ester, 2-3 parts of sericin, 5-7 parts of beewax, 70-100 parts of natural latex, 560-600 parts of an acrylic emulsion, 140-160 parts of titanium dioxide, 0.1-0.2 part of trimellitate, 3-4 parts of nitrilotriacetic acid trisodium salt, 0.6-1 part of wood creosote, 2-3 parts of chlorinated paraffin and 0.3-1 part of alkylated diphenylamine. The coating disclosed by the invention is high in cohesiveness with a wood apparatus, and is high in anti-stripping strength, good in surface flexibility, high in scratch resistance and high in protectiveness to a substrate.

The invention discloses a test method for formaldehyde catalyzing efficiency of a photocatalyst. The test method comprises the following steps: preparing an absorption solution, an AHMT (4-amino-3-hydrazine-5-mercapto-1,2,4-triazole) solution, a potassium hydroxide solution and a potassium periodate solution; adding formaldehyde with different content into the absorption solution, then adding thepotassium hydroxide solution, the AHMT solution and the potassium periodate solution, and measuring the relationship between the content of the formaldehyde and readings of a spectrophotometer by adopting the spectrophotometer; drawing a standard curve; preparing a formaldehyde absorption solution with a certain concentration; stirring with illumination, performing centrifuging, taking supernatant, and adding the potassium hydroxide solution, the AHMT solution and the potassium periodate solution; determining the final content of the formaldehyde by adopting a spectrophotometer method, and dividing the final content of the formaldehyde by the initial content of the formaldehyde to obtain the formaldehyde catalyzing efficiency of the photocatalyst. The formaldehyde catalyzing efficiency ofthe photocatalyst is tested by adopting the method disclosed by the invention easily and quickly; the test method does not have a requirement on equipment environment; a testing purpose can be achieved by a small amount of the photocatalyst; the test method is suitable for a laboratory to use, and has a great application prospect.

The invention provides a kit and a method for rapidly detecting the total amount of ethylene oxide and 2-chloroethanol in a medical instrument. The kit comprises a sodium hydroxide solution, a potassium iodide solution, a mixed solution of periodic acid and hydrochloric acid, a sodium thiosulfate solution, an ethylenediamine tetraacetic acid disodium solution, a 4-amino-3-hydrazino-5-mercapto-1,2,4-triazol solution, a potassium periodate solution and a standard colorimetric card. The method is simple and convenient to operate, low in cost, high in speed and high in sensitivity, can be used forrapidly and simultaneously detecting the residual quantity of ethylene oxide and 2-chloroethanol in a medical instrument on site, can obtain an experimental result within 40 minutes without using special instruments and equipment, and is suitable for rapid detection on site.

The invention provides a method for removing elemental mercury in a flue gas in a liquid phase. The method uses an absorbent to absorb H9O in the flue gas in a jet bubbling reactor, wherein the absorbent consists of an absorption liquid and an additive; the absorption liquid is a solution mixed by copper sulphate CuSO4 and potassium periodate KIO4; the concentration of CuSO4 is 0.001 M to 0.02 M / L, and the concentration of KIO4 is 0.001 M to 0.02 M / L; the additive is one of the following components: potassium bicarbonate KHCO3, hydrogen peroxide H2O2, potassium sulphate K2SO4 and potassium peroxydisulfate K2S2O8; and the concentration of the additive is 0.001 M to 0.05 M / L. The method can reach a removing efficiency of higher than 70 percent. The method for removing the elemental mercury in the flue gas in the liquid phase is characterized by high removing efficiency, low investment and operation costs, simple equipment, stable operation, easy treatment of product, convenient popularization and application and the like, and is suitable for large-size boilers and also suitable for medium and small-size boilers and other coal-burning equipment.

The invention relates to a rapid measurement reagent for manganese concentration in water and a use method thereof. The rapid measurement reagent for the manganese concentration in water comprises a reagent A and a reagent B in a mass ratio of 1:1, wherein (1) the reagent A comprises the following components in percentage by weight: 5.0-15.0 anhydrous potassium pyrophosphate, 10.0-30.0 disodium hydrogen phosphate, 0.5-5.0 citric acid and 60-80 anhydrous sodium sulphate; (2) the reagent B comprises the following components in percentage by weight: 5-25 potassium periodate and 75-95 potassium chloride. The use method of the rapid measurement reagent comprises the following steps: adding the reagent A to a water sample to be measured, adding the reagent B after the reagent A is dissolved; standing for 10 minutes; and comparing colors with a standard colorimetric card, a colorimetric disc or a colorimetric meter, and reading the manganese concentration. The invention has the advantages of simple and convenient operation, accurate results, low price, convenient transportation and carrying, on-site measurement suitability, and the like.

The invention relates to the technical field of coatings, in particular to a preparation method of a wear-resistant coating. The preparation method of the wear-resistant coating comprises the steps ofS1, adding hemp fiber into potassium periodate solution for shaded reaction, then immersing the reacted hemp fiber into glycerol solution, washing the immersed hemp fiber through deionized water, anddrying the washed hemp fiber to obtain modified hemp fiber; S2, mixing and dissolving lignin into dioxane aqueous solution, adding the modified hemp fiber for mixed reaction to obtain a wear-resistant agent; S3, heating a solvent, then uniformly mixing butyl acrylate, silicon dioxide, ethyl cellulose, polyester resin, the wear-resistant agent, polyacrylic acid, silicon carbide, glass fiber and afilm-forming agent, and increasing and keeping the temperature to obtain the wear-resistant coating. The prepared wear-resistant coating is excellent in wear resistance.

The invention provides a glioma-targeting composite nanometer preparation, a preparation method and applications thereof, wherein the glioma-targeting composite nanometer preparation is a nasal nanometer complex assembled by coating a coated material hepatoma-derived growth factor delivery shRNA with a coating material losartan-chitosan-polyethyleneimine vector copolymer, and the particle size is50-250 nm. The preparation method comprises: carrying out an oxidation reaction on chitosan and potassium periodate to obtain oxidized chitosan; carrying out a reaction on the oxidized chitosan and polyethyleneimine to obtain a chitosan-polyethyleneimine copolymer; carrying out a Schiff base reaction on the chitosan-polyethyleneimine copolymer and carboxylated losartan to obtain a losartan-chitosan-polyethyleneimine vector copolymer; and assembling the losartan-chitosan-polyethyleneimine vector copolymer and shHDGF to obtain the nasal nanometer complex. According to the present invention, after the nasal cavity product is prepared from the glioma-targeting composite nanometer preparation, the good brain glioma targeting property can be provided.