The invention belongs to the field of biopesticides, and mainly discloses a nuisanceless biological compound pesticide and a preparation method thereof. The biological compound pesticide is manufactured from the raw materials of Ailanthus altissima Swingle, Cyrtomium fortunei, geranium wilfordii, fructus forsythiae, Scutellaria baicalensis, gallnut, areca-nut, coconut shell, radix sophorae flavescentis, bacillus subtilis, bacillus licheniformis, Streptomyces rimosus and streptomyces aureus. The Chinese herbal medicine extracts of Ailanthus altissima Swingle, Cyrtomium fortunei and the like are added to the pesticide, so that the antibacterial effect of the biopesticide is greatly improved; and moreover, the Chinese herbal medicine extracts are free of toxic action for people and livestock, so that there is no need to worry about causing harmful effects on people and livestock when the pesticide is used. The biopesticide disclosed by the invention has the characteristics of being high in efficiency, environment-friendly, free of secondary toxicity, residues, pollution or public nuisance and unlikely to generate resistance to drugs and keeping ecological balance, is important guarantee for realizing green ecological agriculture and green enterprises, and has wide prospects.