The invention discloses a multi-parameter subsection optimized novel rotating disc extraction column. The multi-parameter subsection optimized novel rotating disc extraction column comprises a column body, a fixing ring, a rotating shaft, rotating discs, a rotating mesh baffle plate, a distributor and an expanding section with structured packing, wherein the rotating discs, the rotating mesh baffle plate and the structured packing can determine the quantity, the size and surface spraying treatment according to the requirements of a separation process; the rotating mesh baffle plate is arranged between the two rotating discs, is fixed on the rotating shaft, and is positioned on the same horizontal plane with the fixing ring; the ratio of the diameter of the rotating mesh baffle plate to the diameter of each rotating disc is 1 to (0.7 to 1.0); holes arrayed in a concentric circle form are formed in the rotating mesh baffle plate; the diameters of the holes are 10 to 30mm; the sizes of the holes can be uniform in diameter, or the holes are multi-aperture, and the aperture ratio is 25 to 60 percent. According to the multi-parameter subsection optimized novel rotating disc extraction column disclosed by the invention, structural parameters such as the diameters of the rotating discs of the extraction column, the diameter of the rotating mesh baffle plate, the space of the fixing ring and the inner diameter of the fixing ring are adjusted, and the rotating mesh baffle plate with multiple apertures and variable aperture ratio are additionally added, so that the efficiency of the extraction column is effectively improved.