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A kind of left auricle occluder framework high-speed electric spark milling processing manufacturing method.First, the shell with the initial form of left auricle occluder framework is prepared by base, upper casting mold, middle casting mold and lower casting mold casting, then the hole for fixing is processed to the shell by drill bit, and then the excess material on the shell is removed by high-speed electric spark discharge milling through the method of high-speed electric spark milling processing on multi-axis linkage electric spark machine tool, the mesh framework semi-finished product with the shell of the part to be processed barb is processed, and the barb is processed using the same high-speed electric spark milling processing method, and the heat treatment memory shaping is carried out through product shaping upper mold, product shaping middle mold, product shaping lower mold and base etc.Finally, the manufacturing is completed after cleaning.The high-speed electric spark milling processing manufacturing method improves the precision, surface quality and consistency of the occluder framework processing, does not need to process special electrode, improves the processing efficiency, reduces the processing cost, solves the problem that left auricle occluder framework cannot be integrally formed and manufactured, and can realize the individual customization of left auricle occluder framework in any form.