The invention discloses a pipeline descaling and antiscaling agent, which comprises various components and the parts by weight of the components are respectively: 4-10 parts by weight of pre-film agent, 3-9 parts by weight of deoxidizer, and scale inhibition 1-5 parts by weight of agent, 2-9 parts by weight of pH regulator, and 70-92 parts by weight of solvent. The pre-filming agent is composed of one or more of zinc sulfate, zinc chloride, and sodium silicate, and the deoxidizer is composed of one or more of azodicarbonamide, sodium sulfite, and isoascorbic acid. The scale inhibitor is composed of one or more of ammonium triacetate, disodium edetate, and sodium polyacrylate, and the pH regulator is composed of one or both of sodium hydroxide and potassium hydroxide Composition, described solvent is water. The descaling and antiscaling agent of the invention has strong stability, long service life, no corrosion effect on pipelines, environmental protection, low price and good effect of descaling and antiscaling.