84results about How to "High graft density" patented technology

The invention relates to a temperature-responsive three-dimensional ordered macroporous controlled-release material. The apertures of a macropore and a communicating window of the controlled-release material are uniform, wherein the aperture of the macropore is 100-1000nm, the communicating window has a size of 40-120nm and the pore volume is 1.3-2.8cm<3> / g; and a substrate of the controlled-release material is monodisperse three-dimensional ordered macroporous crosslinked polystyrene with mutually communicated windows, a polymer chain segment with temperature responsiveness is introduced onto the substrate through an atom transfer radical activity-controlled graft polymerization method, and the on-off control of the communicating window between macropores is realized by utilizing the extending-curling action of the temperature-responsive polymer chain segment under different temperatures: a macroporous chain gradually shrinks along with the temperature rise, the pore window gradually opens, and furthermore, the controlled-release action on filled and packaged substances is achieved. The temperature-responsive three-dimensional ordered macroporous controlled-release material has extensive application values in the fields of controlled-release of biomedicines, drug controlled-release systems, controlled release-embedding of active enzyme and catalysts, and the like.

The invention provides poly (gamma-propargyl-L-glutamate)-polyamino acid segmented copolymer. The poly (gamma-propargyl-L-glutamate)-polyamino acid segmented copolymer is presented as the formula (I). Small molecules containing primary amino radical serve as an initiator, and the poly (gamma-propargyl-L-glutamate)-polyamino acid segmented copolymer is obtained through the gradual ring cleavage reaction of gamma- propargyl-L-glutamate-N-carboxylic acid anhydride and amino acid-N- carboxylic acid anhydride. The side chain of the segmented copolymer is propargyl which is easy to modify, has high reactivity and is beneficial to functional small molecules which are subjected to bonded azide and have biological activity or environmental responsiveness, and the bonding process cannot lead to the breakage of amino acid backbones and is not affected by the amount and steric hindrance of functional small molecules. The segmented copolymer has good biocompatibility after being functionalized and can be applied in fields such as targeted drug delivery, organizational projects and protein separation and detection.

The invention relates to a method for preparing a stimulating responsive polymer brush, in particular to a polymer brush which can modify a surface and has stimulating responsiveness to temperature, and belongs to the technical field of micro nano material preparation. The stimulating responsive polymer brush is obtained by performing surface cleaning on a substrate by using a mixed solution containing concentrated sulphuric acid and hydrogen peroxide, performing epoxy silane coupling agent self-assembly and performing graft by adopting a photoinitiator. The method fixes a thioxanthone photoinitiator containing coinitiator amine on the surface of a base material by self-assembly technology, prepares the polymer brush by surface photo-initiation polymerization, is simple in operation, has the initiator with high graft intensity, high efficiency and speed of initiation polymerization, can be widely suitable for monomers capable of performing photo-initiation polymerization, and has wide application prospect.

The invention relates to an alginate-chitosan microcapsule modified via in situ covalent PEG grafting. The structure of the microcapsule is divided into two parts, i.e., a microcapsule membrane and an inner core, wherein the microcapsule membrane is a polyelectrolyte composite hydrogel membrane formed by chitosan and alginate, the surface of the membrane is modified via in situ covalent PEG grafting, and the inner core is an alginate liquid or alginate hydrogel environment containing living cells. Because of resistance to protein adsorption, the microcapsule is applied to living cell encapsulation and used as an immunoisolation carrier for cell transplantation.

The invention discloses a gradient molecular brush polymer. A main chain of the gradient molecular brush polymer is a copolymer of methyl methacrylate and hydroxyethyl methylacrylate, and a side chain of the gradient molecular brush polymer is polyacrylic acid; and the weight-average molecular weight Mw of the gradient molecular brush polymer is 89600-146900, and the molecular weight distribution is 1.25-1.45. The gradient molecular brush polymer disclosed by the invention is small in molecular weight distribution, high in grafting density, and high in adsorption capacity; and a method for preparing the gradient molecular brush polymer is simple. The gradient molecular brush polymer prepared by adopting the method is accurate and clear, and the molecular structure of the polymer is easily controlled.

The invention relates to an anticoagulant polyurethane material formed by a decorate layer and a base layer, wherein, the base layer is formed by general commercial polyurethane material or composite polyurethane material, and the decorate layer is formed by chemically decorating the face of base layer. The decorate layer contains the PEG flexible distant group connected with the polyurethane base via covalence key and the active lycine lead by the NHS via surface grafting and the function group covalence key at the end of PEG. The inventive preparation comprises that using MDI to function the PU material, surface grafting the PEG, leading in NHS active reaction group, grafting lycine, and de-protecting theepsilon-NH2 of lycine. The invention has better anticoagulant and plug-dissolving functions, to eliminate the blood plug.

The invention discloses a semi-interpenetrating network nano hybrid hydrogel and a preparation method and an application thereof. Firstly, chitosan is modified to prepare water soluble carboxymethyl chitosan (CMCS); then N-isopropylacrylamide (NIPAM), CMCS and (carboxyl functionalized) carbon nanotubes are subjected to in-situ free radical crosslinking polymerization reaction, and the semi-interpenetrating network nano hybrid hydrogel with different composition ratios of NIPAM, CMCS and the nanotubes is obtained. The prepared novel nano hybrid hydrogel has relatively high swelling rate, appropriate volume phase transition temperature and pH phase transition point, and high drug loading amount and continuous controllable drug release behavior. The hydrogel pharmaceutical preparation can be used as a promising hydrophilic oral drug carrier, is used for targeted release of oral vaccines, polypeptides, proteins and anticancer drugs, has low toxicity, and can be used for long-term treatment of colon cancer and the like.

The invention relates to a pH-responsive three-dimensional ordered macroporous controlled-release material. The sizes of macropores and communicating windows of the pH-responsive three-dimensional ordered macroporous controlled-release material are uniform, the sizes of the macropores are 100-1000nm, the sizes of the communicating windows are 40-120nm, and the pore volume is 1.3-2.8 cm<3> / g; the substrate is monodisperse three-dimensional ordered macroporous crosslinked polystyrene with windows which are mutually communicated, and a pH-responsive polymer chain section is introduced into the substrate by an atom transfer free-radical activity-controllable graft polymerization method; and the uncurling-curling action of the pH-responsive polymer chain section under different pH values is utilized to control the opening and closing of the communicating windows among the macropores: as the pH value increases, macromolecule chains gradually uncurl, and the pore windows are gradually closed, thereby realizing the controllable release of the contained filler. The pH-responsive three-dimensional ordered macroporous controlled-release material has wide application values in the controlled-release fields of biomedicine, medicine controlled-release systems, organized enzymes, slow release-embedding of catalysts, and the like.

The invention provides magnetic shell-core structural nanoparticles and a preparation method and application thereof. The magnetic shell-core structural nanoparticles comprise a plurality of magnetic nanoparticles, silica shell layers coating the plurality of magnetic nanoparticles, porous silica shell layers coating the silica shell layers and dipeptide-functionalized polymer grafted to surfaces of the porous silica shell layers. The method comprises: preparing magnetic nanoparticles, coating the silica shell layers and the porous silica shell layers with the magnetic nanoparticles, performing modification with a siloxane crosslinking modifier, and finally grafting the surfaces of the porous silica shell layers, which is modified with siloxane, with the dipeptide-functionalized polymer to obtain the magnetic shell-core structural nanoparticles. The magnetic shell-core structural nanoparticles can be applied to enrichment and separation of glycosylated protein. The magnetic shell-core structural nanoparticles successfully combine with dispersive solid-phase extraction, thereby achieving high-selectivity, good-repeatability and high-throughput enrichment of glycosylated protein and polypeptide materials.

The invention relates to a polyester film, which belongs to the technical field of surface modification of organic film materials, and in particular to a preparation method for a surface-grafted polyacrylic acid lead polyester film. The invention provides a preparation method for a surface-grafted polyacrylic acid lead polyester film, which can contribute to realizing uniform surface grafting and has high grafting density. The method is characterized in that: the polyester film material is subjected to a series of surface treatment, a bromo-ester initiator is fixed on the surface of the polyester film material, and polyacrylic acid lead is grafted to the surface of the polyester film with a surface initiated atom transfer free radical polymerization method. The method has a simple process and a good modifying effect. By grafting the polyacrylic acid lead with a cross-linked structure formed by ion bonds on the surface of the polyester film with the method, the surface electrics and surface free energy of the polyester film can be improved effectively, and the surface performance of the modified polyester film can be controlled by changing reacting time.

The invention discloses a method for performing surface treatment on a material for boosting cell growth and resisting biological pollution, which comprises the following steps: firstly, performing activating treatment on a material surface, and performing surface self-assembly reaction; and then fixing amphoteric-ion molecules and polyethylene glycol molecules with the characteristics of resisting biological pollution and extracellular matrix proteins or albumen polypeptides for boosting cell growth on the material surface in turn, thereby obtaining a material with the characteristics of boosting cell growth and resisting biological pollution. By performing surface treatment on the material according to the method provided by the invention, the material surface is simultaneously endowed with the capabilities of resisting biological pollution and boosting cell growth. The method is applied to the fields of biological materials, tissue engineering, nanometer material research, and the like.

The invention relates to a nanofiber substrate as well as a preparation method of the nanofiber substrate and applications of the nanofiber substrate in CTC efficient capture and non-destructive release. The nanofiber substrate provided by the invention comprises a lining substrate, a nano-structure layer, an adhesion-resisting molecular layer and an affinity capture molecular layer which are connected in sequence. The preparation method of the nanofiber substrate comprises the following steps: preparing for the lining substrate; depositing the nano-structure layer on the lining substrate; grafting the adhesion-resisting molecular layer to the nano-structure layer; and connecting the affinity capture molecular layer on the adhesion-resisting molecular layer. The nanofiber substrate provided by the invention has good cell compatibility, the captured CTC sample has relative high activity and purity, and free CTC samples can be obtained through the hybridization effect of complementary chains and aptamers.

The invention relates to a DEAE dextran-modified agarose gel-based chromatography medium and a preparation method and application thereof. The method includes the steps that first, the molecular weight of DEAE Dextran for grafting is selected; next, the concentration of a DEAE Dextran aqueous solution is controlled; then, the time of diffusion before DEAE Dextran coupling is determined; finally, the reaction time of coupled DEAE Dextran and the concentration and volume of sodium hydroxide are determined. The DEAE dextran-modified agarose gel-based chromatography medium has a strong adsorption property for protein under different modification densities, shows a high adsorption capacity and a high adsorption rate and improves separation efficiency. The medium is convenient to clean and degerm, easy to regenerate and good in biocompatibility. The preparation method is simple and harmfulless and has broad application prospects in efficient and rapid separation and purification of protein.

The invention discloses a thrombus filter capable of realizing delayed recovery and a preparation method of the thrombus filter and particularly discloses a blood compatible coating. The blood compatible coating comprises a polyacrylic acid layer and a polyethylene glycol layer, and 2-methacryloyloxyethyl phosphorylcholine is covalently linked with the surface of the polyethylene glycol layer. Theinvention further discloses medical apparatus such as the thrombus filter coated with the blood compatible coating. According to the technical scheme, thrombogenesis and endothelial tissue growth canbe better inhibited. The whole surface coating is adjustable in thickness and surface grafting amount and can well bear stress and strain actions in apparatus assembly and release processes, molecules are firmly combined without falling off, and mechanical properties of the apparatus are not affected.

The present invention discloses an anti-impact heat-dissipating coating material, which which comprises the following raw materials by weight: 4-7 parts of soapstone, 2-3 parts of polyether diol, 12-15 parts of a styrene-maleic anhydride copolymer, 6-10 parts of propargyl alcohol, 90-100 parts of tetrahydrofuran, 4-7 parts of graphene, 16-20 parts of nanometer silica, 0.2-0.3 part of a silane coupling agent KH560, 700-800 parts of dimethylformamide, 4-5 parts of sodium nitride, 0.04-0.05 part of aluminum trichloride, 1.6-2 parts of a 2-3% sodium ascorbate solution, 1.8-2 parts of a 2-3% copper sulfate solution, 120-130 parts of high-density polyethylene, 0.1-0.3 part of sodium fluoroborate, 3-4 parts of dibutyl phthalate, 0.7-2 parts of 8-hydroxyquinoline, and 1-2 parts of calcium propionate. According to the present invention, the coating material is added with the soapstone, the graphene, the nanometer silica and the like as the filler particles, such that the good anti-impact strength is provided.

The invention relates to the field of polymer synthesis. The invention provides a preparation method of an ultra-high graft density polymer molecular brush. The method comprises the following steps: firstly, preparing a SiO2 / Si substrate by using a single-crystal silicon wafer, and then self-assembling an initiator monomolecular layer on the surface of the SiO2 / Si substrate, wherein an initiator is 22-(trichlorosilyl)docosa-2-bromo-2-phenylacetate; finally, under nitrogen protection, enabling the product to react with cuprous bromide, styrene, pentamethyl diethyl triamine and toluene to prepare the ultra-high graft density polymer molecular brush. The results of the embodiments show that the thickness of the polymer molecular brush is 55-65 nm, and the graft density of the polymer molecular brush is 1.21-1.23 chains / nm<2>.

The invention discloses L-carnitine molecularly imprinted microspheres with a core-shell structure and a preparation method thereof, and relates to the field of intelligent high polymer materials. According to the invention, L-carnitine is taken as a template molecule and methacrylic acid is taken as a functional monomer, and the L-carnitine molecularly imprinted microspheres with the core-shell structure are prepared through reversible addition-fragmentation chain transfer and free radical polymerization in combination with the surface molecular imprinting technology; the preparation method of the L-carnitine molecularly imprinted microspheres with the core-shell structure comprises the following steps of: 1, preparing nano SiO2 microspheres by a Stober method; 2, performing surface activation on the nano SiO2 microspheres; 3, performing surface benzylation on the nano SiO2 microspheres; 4, synthesizing an RAFT (Reversible Addition-Fragmentation Chain Transfer Polymerization) reagent on the surface of the nano SiO2 microspheres; 5, preparing the L-carnitine molecularly imprinted microspheres with the core-shell structure; and 6, eluting the imprinted template molecules. The L-carnitine molecularly imprinted microspheres with the core-shell structure has the advantages of simple process, low cost, convenience in industrial popularization and application, and the like; the obtained imprinted microspheres have good adsorbability and selectivity for L-carnitine molecules, and can be applied to separating out carnitine enantiomers.

The invention discloses a method for reducing friction coefficient by surface finishing, which belongs to the technical fields of organic chemical grafting finishing and friction-pair surface modification treatment. The method includes: performing surface activating treatment for a friction pair by ultraviolet irradiation or plasmas, coating silane solution on the surface of the friction pair for multiple times for chemical finishing; disposing the friction pair into lubricants required by different working conditions so that the finished friction pair can be lubricated sufficiently; and enabling the friction pair to start operating. The friction coefficient can be simply and conveniently reduced by about one order of magnitude from the original friction coefficient by the method, and further, the fine friction reduction effect in a long time is achieved, and the method can be applied to various friction pair surfaces requiring friction reduction.

The present invention discloses a light-extinction heat-dissipating coating material, which comprises the following raw materials by weight: 1-2 parts of calcium linoleate soap, 1-2 parts of magnesium myristate soap, 12-15 parts of a styrene-maleic anhydride copolymer, 6-10 parts of propargyl alcohol, 90-100 parts of tetrahydrofuran, 4-7 parts of graphene, 16-20 parts of nanometer silica, 0.2-0.3 part of a silane coupling agent KH560, 700-800 parts of dimethylformamide, 4-5 parts of sodium nitride, 0.04-0.05 part of aluminum trichloride, 1.6-2 parts of a 2-3% sodium ascorbate solution, 1.8-2 parts of a 2-3% copper sulfate solution, 160-170 parts of high-density polyethylene, 0.7-2 parts of polyimide, 6-10 parts of diatomite, 0.8-1 part of castor oil polyoxyethylene ether, 3-4 parts of barium stearate, and 1-2 parts of chlorinated paraffin. According to the present invention, the diatomite, the polyimide, the calcium linoleate soap and the like are added, such that the mirror surface reflection effect of the paint film surface light can be reduced and the rough surface can be formed so as to achieve the light extinction effect.

The invention discloses a polymer brush type magnetic graphene oxide adsorbing material and a preparation method thereof, and relates to the field of adsorbing materials. The adsorbing material provided by the invention comprises graphene oxide, magnetic Fe3O4, polydopamine and a polymer brush. The magnetic Fe3O4 is dispersed on the surface of the graphene oxide in a nano-particle shape to form magnetic graphene oxide; the surface of the magnetic graphene oxide is coated with the polydopamine; the polymer brush is grafted on the polydopamine; the polymer brush includes poly(4-sodium vinylbenzene sulfonate-co-methacryloyloxyethyl trimethyl ammonium chloride). The polymer brush grafted on the surface of the adsorbing material has characteristic functional groups, so that the adsorption selectivity is improved. According to the preparation method of the adsorbing material, graphene with a large specific surface area is used as a matrix, the polymer brush is grafted by combining an SI-ATRPtechnology with a high grafting characteristic, a grafting layer is uniform, the grafting density is high, and the density of functional groups is effectively improved, so that the adsorption capacity of the adsorbing material is improved.

The invention relates to an amino silane modified nanocellulose aerogel preparation method. The method includes: 1) making nanocellulose suspension liquid into semi-transparent colloid; 2) extruding the nanocellulose colloid to form spherical or short rod-like hydrogel; 3) turning the formed nanocellulose hydrogel into alcogel; 4) making nanocellulose aerogel; 5) allowing adsorption of gaseous organic amine on the surface of the nanocellulose aerogel; 6) performing vacuum recovery of residual organic amino catalysts; 7) allowing chemical reaction of gaseous amino silane and the nanocellulose aerogel; 8) performing vacuum recovery of unreacted amino silane and 9) making corresponding amino silane modified nanocellulose aerogel. The method has advantages that 1) solvent recovery and separation in a liquid-phase modification process can be avoided, and an amination modification process is simplified; 2) an original microcosmic three-dimensional network structure of nanocellulose aerogel is kept, and modification grafting density and uniformity are improved; 3) process simplicity, high efficiency and low cost are realized.

The invention provides a method for grafting DNA on polydopamine nanoparticle surface with controllable density. According to the method, the grafting density of DNA on polydopamine nanoparticle surface is controlled in the manner of adding metal cations into a reaction system. According to the method provided by the invention, the DNA grafted polydopamine nanoparticle with controllable grafting density can be acquired, wherein the maximal grafting density of DNA on the surface of polydopamine nanoparticle in grain size of 250nm can reach up to 34.60pmol / cm2 and is far more than the maximal grafting density (21pmol / cm2) of DNA on the surface of gold nanoparticle in grain size of 250nm.

The present invention discloses hard heat-dissipation paint. The hardheat-dissipation paint consists of the following raw materials in parts by weight:2-3 parts of ethylene glycol distearate, 12-15 parts of styrene-maleic anhydride copolymer, 6-10 parts of propargyl alcohol, 90-100 parts of tetrahydrofuran, 4-7 parts of graphene, 16-20 parts of nano silica, 0.2-0.3 part of a silane coupling agent KH560, 700-800 parts of dimethyl formamide, 4-5 parts of sodium nitride, 0.04-0.05 part of aluminium trichloride, 1.6-2 parts of a 2-3% sodium ascorbate solution, 1.8-2 parts of a 2-3% copper sulfate solution, 120-130 parts of high density polyethylene, 2-3 parts of barium metaborate, 0.8-1 part of calcium palmitate, 0.7-2 parts of allythiourea, 0.6-1 part of poly(oxypropylene) diol, 1-2 parts of aluminosilicate fibers, and 0.1-0.2 part of aluminum isopropoxide. The paint provided by the present invention is high in the surface hardness, good in the impact resistance, good in weather-ability, high in coating membrane stability, and superior in synthesis performance.

The invention discloses acrylic acid acidized polyacrylate capable of realizing ultraviolet curing as well as a preparation method and an application of acrylic acid acidized polyacrylate. Single functional monomers including MMA (methyl methacrylate), BA (butyl acrylate) and HEMA (hydroxyethyl methylacrylate) and bifunctional monomers including GMA (glycidyl methacrylate) are adopted for copolymerization, polyacrylate resin is obtained, and various properties such as weather fastness, film-forming property, water resistance, solvent resistance and the like of the polyacrylate resin are improved. Acrylic acid and hydroxyl as a lateral group contained in main chains of the polyacrylate resin are adopted for acidification, so that the grafting density of double bonds can be greatly increased, part of hydroxyl is reserved in a polyacrylate copolymer through adjustment of the acidification degree, the copolymer has a higher curing speed, has quite excellent dispersing and stabilizing effects on pigments and has outstanding functions in the aspect of photo-curing printing ink configuration.

The invention discloses a straw fiber doped polyaniline electromagnetic shielding material and a preparation method of the straw fiber doped polyaniline electromagnetic shielding material. The preparation method comprises the following steps: under the condition of -8 DEG C to 0 DEG C, dropwise adding an oxidation solution into a raw material solution containing a polyaniline monomer and straw fibers by adopting a peristaltic pump; slowly stirring; after dropwise adding, stopping stirring and continually reacting for 10h to 16h; after reacting, filtering and centrifuging and washing with absolute ethyl alcohol for 3 to 5 times; after drying in vacuum, preparing the straw fiber doped polyaniline electromagnetic shielding material. The preparation method of the shielding material is simple; raw materials are cheap and easy to obtain; the shielding material has high shielding efficiency, a wide range and good industrialized production prospect.

The present invention discloses an Eva emulsion heat radiating coating. The Eva emulsion heat radiating coating is prepared from the following raw materials in parts by weight: 2-4 parts of calcium fluoride, 6-10 parts of an Eva emulsion, 12-15 parts of a styrene and maleic anhydride copolymer, 6-10 parts of propargyl alcohol, 90-100 parts of tetrahydrofuran, 4-7 parts of graphene, 16-20 parts of nano silicon dioxide, 700-800 parts of dimethylformamide, 4-5 parts of sodium nitride, 0.04-0.05 part of aluminium trichloride, 1.6-2 parts of a 2-3% sodium ascorbate solution, 1.8-2 parts of a 2-3% copper sulfate solution, 120-130 parts of high density polyethylene, 0.7-1 part of ricinoleic acid, 3-4 parts of dimethyl Methylphosphorate, 2-3 parts of diphenyl silandiol, 0.7-1 part of ammonium molybdate, 1-2 parts of polybenzimidazole fiber and 0.4-0.5 part of a silane coupling agent KH560. According to the present invention, by adding the Eva emulsion, the compatibility of materials among resin can be improved, the dispersibility of particles is improved, and the heat-conducting and heat radiating effect is improved.

The invention discloses extreme-pressure lubricating and cutting liquid which consists of the following raw materials in parts by weight: 1 to 2 parts of N-hydroxymethyl acrylamide, 3 to 4 parts of isopropyl palmitate, 1 to 2 parts of para toluene sulfonamide, 4 to 6 parts of T405 sulfurized olefin cottonseed oil, 0.2 to 0.3 part of copper sulfate, 10 to 17 parts of styrene, 3 to 4 parts of maleic anhydride, 0.1 to 0.2 part of benzoyl peroxide, 5 to 7 parts of nano-silicon dioxide, 1 to 2 parts of propargyl alcohol, 0.4 to 1 part of sodium nitride, 0.6 to 1 part of aluminum chloride, 0.7 to 1 part of a silane coupling agent kh560, 0.1 to 0.2 part of sodium ascorbate, 2 to 3 parts of polyoxypropylene glycerol ether, 2 to 3 parts of polyglycerol fatty acid ester, 0.1 to 0.2 part of molybdenum oxide and 2 to 3 parts of calcium phosphate. Unsaturated residual bond and hydroxyl with different bonding states which exist on the surface of the nano-silicon dioxide enable the surface of the nano-silicon dioxide to achieve high surface activity, and the nano-silicon dioxide is easily deposited on the friction surface of metal, so that the lubricating property of the cutting liquid is improved.

The invention discloses a preparation method capable of preparing a superparamagnetic Fe3O4 nanorod with controllable size and dispersity in a large scale, belonging to the multidisciplinary fields like polymer active polymerization process, functional polymer molecular design and inorganic crystal growth. The method comprises the following steps: (1) with an ionic liquid AMIMCl as a solvent and anhydrous dimethylformamide and N-methylpyrrolidone as a diluent and an acid absorbent, modifying hydroxyl on the chain of cellulose by using 2-bromoisobutyryl bromide so that a macromolecular initiator capable of being used for atom transfer radical polymerization is obtained; (2) by utilizing a continuous polymerization ATRP technology and a click chemistry reaction, respectively preparing a series of brush-shaped di-block polymers, i.e., cellulose-g-[PAA-b-PS] and cellulose-g-[PAA-b-PEG]; and (3) on the basis of a solution phase synthesis method, and with a certain amount of the above-mentioned prepared brush-shaped di-block polymers as a monomolecular template and FeCl2.4H2O, FeCl3.6H2O and NH3.H2O as a precursor compound system, preparing the superparamagnetic Fe3O4 nanorod with oil dispersity and water dispersity.

The invention relates to an alginate-chitosan microcapsule modified via in situ covalent PEG grafting. The structure of the microcapsule is divided into two parts, i.e., a microcapsule membrane and an inner core, wherein the microcapsule membrane is a polyelectrolyte composite hydrogel membrane formed by chitosan and alginate, the surface of the membrane is modified via in situ covalent PEG grafting, and the inner core is an alginate liquid or alginate hydrogel environment containing living cells. Because of resistance to protein adsorption, the microcapsule is applied to living cell encapsulation and used as an immunoisolation carrier for cell transplantation.