The invention discloses a recyclable photocuring 3D printed soluble microneedle patch and a preparation method thereof. The microneedle patch is composed of a soluble needle body layer and a flexible recoverable backing layer. The needle body layer is prepared into a polymerizable eutectic
solvent through a specific composition, eutectic gel of a multi-
hydrogen-bond cross-linked network is formed during photopolymerization, and rapid
dissolution and effective
drug delivery can be achieved. Eutectic gel prepared from the backing layer by utilizing a similar principle can be dissolved and recycled through
ethanol and is circularly printed. The DLP 3D printing technology is utilized, personalized manufacturing of the soluble microneedle patch is achieved, meanwhile, the problem that a traditional microneedle backing layer cannot be recycled is solved, resource waste and environmental
pollution are reduced, and the soluble microneedle patch is suitable for multiple fields such as
drug delivery,
vaccination and skincare.