The invention relates to a method for preparing a covalent organic framework material by high-pressure homogenization. According to the synthesis method, at normal temperature and normal pressure, a common organic ligand is used as a raw material, water or an organic reagent is used as a solvent and a template agent, organic acid and inorganic acid are used as catalysts, and the corresponding COFs are obtained by homogenizing for a certain time through a high-pressure homogenizer. The method comprises the following steps of: adding 2, 4, 6-trihydroxy-1, 3, 5-benzenetricarboxaldehyde and p-phenylenediamine into a beaker, adding a proper amount of water and acetic acid, uniformly mixing, adding the mixture into a high-pressure homogenizer, and homogenizing for a certain time; and carrying out suction filtration on the product powder after the homogenizing reaction, recycling the filtrate, washing the product powder, and carrying out vacuum drying to obtain the covalent organic framework material HPH-Tp-Pa-1. Compared with other COFs preparation methods, the method provided by the invention has the advantages of continuous reaction, simple operation, low cost, high yield, environmental protection, energy saving, short reaction time and the like, has the potential of large-scale production, and can greatly promote the industrial production process of the COFs material.