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47results about How to "Prolong the duration of action" patented technology

Ganciclovir ophthalmic gel and its prepn. method

An eye gel of Ganciclovir for treating viral keratitis is proportionally prepared from ganciclovir and eye gel matrix through mixing Ganciclovir, eye gel matrix and water, stirring, regulating pH value, adding water, stirring and sterilizing.
Owner:湖北科益药业股份有限公司

Ecological environment sand fixing material and preparation method thereof

The invention discloses an ecological environment sand fixing material and a preparation method thereof, which belongs to the technical field of sand environmental governance. The preparation method comprises the following steps: oxidizing and homogenizing wood pulp used as a raw material to obtain nano fibers, adsorbing silicon dioxide on the surface of the nano fibers, by adopting the silicon dioxide as a supporting material, slowing heating, carbonizing the nano fibers to obtain nano fibers of a hollow structure, taking the hollow nano fibers as carriers, respectively wrapping polyaspartic acid emulsion and a hexanediamine solution inside the hollow fibers, performing end-sealing treatment by virtue of urea resin, respectively preparing a fiber component A and a fiber component B, and then compounding with chitosan, glutaraldehyde, casein, borax, polyethylene glycol and the like, thus obtaining the ecological environment sand fixing material. The sand fixing material is short in setting time, has a good sand fixing effect, and is capable of creating a good water-soil environment to the growth of plants, capable of effectively improving the ecological environment, and capable of facilitating the growth of desert plants.
Owner:常州新之雅装饰材料有限公司

Aciclovir high-molecular hydrogel dressing and its preparation method

The invention discloses a making method of Asiluowei macromolecular gel dressing, which comprises the following steps: dissolving N, N'-methylene diacrylamide into acroleic acid completely to obtain solution A; dissolving Asiluowei powder into sodium hydroxide solution to obtain solution B; dissolving polyvinyl alcohol solution, glycerin, potassium persulfate solution and water completely to obtain solution C; dripping solution A into solution B to react; adding solution C; stirring evenly; pouring into mould; heating to polymerize and crosslink to obtain the product to treat herpes zoster.
Owner:SOUTH CHINA UNIV OF TECH

High-viscosity asphalt material for purifying automobile tail gas, and preparation method thereof

The invention discloses a high-viscosity asphalt material for purifying automobile tail gas, and a preparation method thereof. The high-viscosity asphalt material comprises the following raw materialcomponents in parts by weight: 100 parts of matrix asphalt, 5-15 parts of a styrene-butadiene block copolymer, 1-20 parts of aromatic-rich oil, 0.1-1 part of a stabilizing agent, 1-20 parts of a porous carbon material, and 1-20 parts of an asphalt modifier, wherein the asphalt modifier uses a lanthanum-based metal oxide as a carrier and uses a transition metal oxide as a catalytic active component, and the use amount of the transition metal oxide is 5-100% of the mass of the lanthanum-based metal oxide. The high-viscosity asphalt material disclosed by the invention can efficiently and permanently purify nitrogen oxides and other main pollutants in automobile tail gas within a pavement temperature range in the presence or absence of sunlight while effectively reduces urban road surface noise pollution, enhances road surface friction force and inhibits water film generation, and can be widely applied to construction of modern asphalt road surfaces and sponge cities.
Owner:CHINA PETROLEUM & CHEM CORP +1

Steady-state polycarboxylate superplasticizer with core-shell structure and preparation method of steady-state polycarboxylate superplasticizer

The invention discloses a steady-state polycarboxylate superplasticizer with a core-shell structure and a preparation method of the steady-state polycarboxylate superplasticizer. The core structure ofthe steady-state polycarboxylate superplasticizer with the core-shell structure is obtained by emulsion polymerization of a vinyl glycol ether monomer containing hydrophobic chain segments, a derivative monomer A of the vinyl glycol ether monomer, an unsaturated carboxylic acid or an anhydride monomer B, an alkyl acrylate monomer C and an allyl polyether reactive emulsifier D; wherein the shell structure is obtained by polymerizing a vinyl polyethylene glycol ether monomer and a derivative monomer E thereof, an unsaturated carboxylic acid or anhydride monomer B and a (methyl) acrylic acid hydroxyl ester unsaturated small molecular substance F through an aqueous solution. The preparation method of the steady-state polycarboxylate superplasticizer is simple, the initial dispersity is good in engineering use, the fluidity of concrete can be kept for a long time, the workability of the concrete can be remarkably improved, and the steady-state polycarboxylate superplasticizer has excellentmaterial adaptability.
Owner:JIANGSU SOBUTE NEW MATERIALS +2

Preparation method of polyester fabric

The invention belongs to the technical field of polyester fabric and particularly relates to a preparation method of polyester fabric. The preparation method of the polyester fabric comprises five steps of selecting and checking raw materials, bleaching and airing the qualified raw materials, soaking and drying, weaving as well as performing film plating and hole opening. Lemon-grass oil serves asa main component of mosquito repellent, the lemon-grass oil consists of geranialdehyde, neral, geraniol, geranic acid and linalool, mosquitoes can be effectively repelled, chrysanthemum, mint leaf and xanthium serve as auxiliary components of the mosquito repellent, and xanthostrumarin in the xanthium has mild or moderate inhibition effect on fungi in the air, so that the lemon-grass extract canbe prevented from going mouldy and the action time of the lemon-grass extract is prolonged.
Owner:张锦潇

Self-assembled carnosine fluorescent nanoparticles, preparation method and application

The invention discloses self-assembled carnosine fluorescent nanoparticles. The self-assembled carnosine fluorescent nanoparticles are nanoparticles with regular crystal structures; carnosine monomersare taken as main bodies and coordinate with metal ions through pi-pi accumulation among imidazole rings of the carnosine monomers to form the self-assembled carnosine fluorescent nanoparticles; andthe diameters of the self-assembled carnosine fluorescent nanoparticles are 15 nm to 100 nm. According to the self-assembled carnosine fluorescent nanoparticles, the stability of carnosine is improved, the self-assembled carnosine fluorescent nanoparticles can be slowly degraded after being administrated, and the carnosine is released, so that the acting time of a drug is prolonged.
Owner:NORTHWESTERN POLYTECHNICAL UNIV

Endoscopic treatment gastric ulcer dressing device

The invention discloses an endoscopic treatment gastric ulcer dressing device. The endoscopic treatment gastric ulcer dressing device comprises an endoscope, a placing umbrella, a body, a protective film and a pulling rope, wherein the placing umbrella is connected with the endoscope, the body is fixed to the bottom of the placing umbrella through a connecting rope and used for storing dressing, the protective film is bonded to the bottom of the body and used for protecting the sealing performance of the body, the top of the pulling rope is connected to the left side of the placing umbrella, the periphery of the protective film is covered with the bottom of the pulling rope, and the pulling rope is fixedly connected with the right side of the protective film; seepage absorption bins for placing hemostasis damask silk are formed in the left side and the right side of the interior of the body, and a medicine release bin for adding medicine is arranged in the body and in the middle of theseepage absorption bins; the bottom of the body and the outer sides of bin openings of the seepage absorption bins are provided with adhesive films used for being attached to normal digestive walls on the periphery of ulcer; and the placing umbrella is made of rubber materials, and an iron wire used for adjusting the angle of the body is arranged in an umbrella handle of the placing umbrella.
Owner:SOUTHWEST MEDICAL UNIVERISTY

Cooling device for optical fiber drawing

The invention relates to the technical field of optical fiber drawing equipment, and discloses a cooling device for optical fiber drawing, which comprises a tower body, the inner wall of the tower body is continuously provided with a cooling unit consisting of an air blowing part and an air suction part from top to bottom, and in each unit, the air suction part is arranged at the upstream of the air blowing part, and the air suction part is arranged at the downstream of the air blowing part. The air blowing part and the air suction part are connected with an air outlet channel and an air suction channel respectively. According to the cooling device for optical fiber drawing, after the cooling gas is introduced, the gas repeatedly rolls in the cavity, so that the acting time of the gas is greatly prolonged, the use amount of the cooling gas is reduced, the cooling device is particularly suitable for helium with higher value, and the cooling requirement can be met only by using a small amount of gas; the air continuously performs small circulation in the cooling unit formed by the air blowing part and the air suction part, the air always keeps low temperature in the circulation, and secondly, the flow speed is increased, so that a boundary layer around the optical fiber can be directly damaged, the air is uniformly mixed, and the cooling capacity is further enhanced.
Owner:郭俊滔

Lignosulfonate-polyvinyl alcohol blended coated soil conditioner and preparation method thereof

The invention relates to a lignosulfonate-polyvinyl alcohol blended coated soil conditioner and a preparation method thereof. The lignosulfonate-polyvinyl alcohol blended coated soil conditioner comprises a calcareous conditioner and a coating coated on the outer side of the calcareous conditioner, wherein the coating comprises the following raw materials in parts by weight: 2 to 10 parts of lignosulfonate, 9 to 11 parts of polyvinyl alcohol, 2 to 10 parts of urea, 1 to 10 parts of formaldehyde and 48 to 52 parts of water. The lignosulfonate-polyvinyl alcohol blended coated soil conditioner prepared by using the method provided by the invention can be applied to improvement of acidity of farmland soil and treatment of heavy metal pollution, is safe and hazard-free, mitigates stimulation and injury to users, facilitates transportation of calcareous substances, and has the effect of improving acidic soil better than the effect of improving the acidic soil by directly applying the calcareous substances.
Owner:郑州恒达会展服务有限公司

Metal stamping part surface treating agent and surface treatment process

The present invention proposes a surface treatment agent and a surface treatment process for metal stamping parts. The surface treatment agent comprises the following parts by mass: 20-30 parts of silica sol, 1-5 parts of vinyl acetate, and 0.5-2 parts of alkyl glycoside , 2-5 parts of epoxy fatty acid methyl ester, 3-6 parts of alkanolamide, 2-4 parts of lithium silicate, 1-3 parts of trifluoroethyl methacrylate, 3 parts of hydroxyl-terminated polydimethylsiloxane ‑5 parts, water 0‑30 parts, made by heating, stirring, water bath, ultrasonic and other steps, combined with tung oil for the surface spraying treatment of metal stamping parts, greatly improving the wear resistance, corrosion resistance, corrosion resistance of metal stamping parts Rust, waterproof and stain-resistant properties, and strong bonding with the metal surface, with a certain degree of self-drying, which significantly improves the overall performance of metal stamping parts and prolongs the service life.
Owner:周楠

Washing machine washing and bleaching integrated washing method and washing machine

The invention provides a washing machine washing and bleaching integrated washing method. The method comprises the following steps that 1, a water inlet system performs primary water inflow; 2, a washing system executes a main washing program; 3, a drainage system performs partial draining; 4, a water inlet system performs water inflow, and the washing system executes a continuous washing program;5, the washing system judges whether or not the washing water meets the preset condition, if not, step 3 is executed, and if yes, step 6 is executed; 6, the drainage system performs complete draining. Accordingly, by integrating ordinary washing and bleaching processes, during the washing and bleaching integration period, a method of multiple partial discharging-water reentering is adopted, and then the problem that due to attachment of detergent residual components and washing dirt, the clothes are yellow and dark is avoided to the maximum extent; meanwhile, the contact time of detergent andclothes dirt is prolonged, the detergent can fully remove stains for the clothes, and the clean ratio in the washing process is increased conveniently.
Owner:SHANGHAI XIAOJI INTERNET TECH CO LTD

Sweat-absorbing-and-deodorizing slippers and preparing technology thereof

The present invention proposes a sweat-absorbing and deodorant slippers and a preparation process thereof, comprising a plastic shoe body and a fiber lining, the plastic shoe body including a sole and a vamp, the upper surface of the sole and the lower surface of the vamp are fitted by Velcro. There is the fiber lining, the plastic shoe body is made of modified polyurethane material, and the fiber lining is modified blended fiber cloth. The slipper of the present invention adopts a two-layer structure, and the plastic shoe body and the fiber lining can be connected by Velcro. Tear and fit, easy to clean and replace. Compared with disposable slippers, it is safe and environmentally friendly, and can effectively reduce costs. In addition, the plastic shoe body made through a reasonable formula combination is comfortable, soft, strong and tough, antibacterial and wear-resistant, and with fiber The lining absorbs sweat, deodorizes, sterilizes, and has good air permeability, which improves the overall quality.
Owner:安徽爱舍家居制品有限公司

Aciclovir high-molecular hydrogel dressing and its preparation method

The invention discloses a making method of Asiluowei macromolecular gel dressing, which comprises the following steps: dissolving N, N'-methylene diacrylamide into acroleic acid completely to obtain solution A; dissolving Asiluowei powder into sodium hydroxide solution to obtain solution B; dissolving polyvinyl alcohol solution, glycerin, potassium persulfate solution and water completely to obtain solution C; dripping solution A into solution B to react; adding solution C; stirring evenly; pouring into mould; heating to polymerize and crosslink to obtain the product to treat herpes zoster.
Owner:SOUTH CHINA UNIV OF TECH

Water dispersible granule containing pyraclostrobin and preparation method thereof

The invention provides a water dispersible granule containing pyraclostrobin and a preparation method thereof. The water dispersible granule containing pyraclostrobin is prepared according to the following steps: heating and fusing pyraclostrobin and then adopting an interfacial polymerization method for preparing a microcapsule preparation with average grain diameter of 0.5um-2.0um; uniformly mixing the microcapsule preparation with water-based grinding paste of auxiliaries with average grain diameter of 0.5um-2.0um or water-based grinding paste containing tebuconazole or cymoxanil; performing spray drying, thereby acquiring the water dispersible granule. According to the invention, pyraclostrobin is prepared into a nearly spherical aqueous suspension of microcapsule pesticide, so that the technical problem of easiness in melting, adhering or livering of pyraclostrobin during a fluid energy milling or sanding process can be avoided, and the dispersity, suspensibility, storage stability, and the like, of the water dispersible granule containing pyraclostrobin are promoted. The water dispersible granule containing pyraclostrobin provided by the invention has a certain slow release effect and is capable of persistently and effectively controlling various plant diseases.
Owner:SHENZHEN NOPOSION AGROCHEM

Targeted liposome drug delivery system and preparation method and application thereof

The invention discloses a targeted liposome drug delivery system, the drug delivery system is composed of a targeting ligand modified liposome entrapped hardener, and the targeting ligand is hyaluronic acid. The hardener used in the invention is a water-soluble small molecule drug, and the liposome membrane material is prepared from lecithin, cholesterol and distearoyl phosphatidyl ethanolamine-polyethylene glycol-targeting ligand in a mass ratio of (30-32): (7-9): 1. The liposome has a phospholipid bilayer, is self-closed in structure, can entrap a hardener inside the liposome, has good stability, and can prevent water-soluble drugs from being rapidly degraded and reduce the release speed of the drugs. In addition, hyaluronic acid is used for modifying the drug-loaded liposome, so targeted transportation of the drug in lymphangial malformation pathological tissues can be realized.
Owner:BEIJING CHILDRENS HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV

High-viscosity asphalt modifier, high-viscosity asphalt material and preparation methods of high-viscosity asphalt modifier and high-viscosity asphalt material

The invention discloses a high-viscosity asphalt modifier, a high-viscosity asphalt material and preparation methods of the high-viscosity asphalt modifier and the high-viscosity asphalt material. The high-viscosity asphalt modifier takes a carbon nanotube as a carrier and a transition metal oxide as a catalytic active component; the using amount of the transition metal is 10%-100% of the mass of the carbon nanotube. The outer diameter of the carbon nanotube is 50-100 nm, the purity is greater than 95 wt%, and the specific surface area is greater than 100 m < 2 > / g. The invention also provides a high-viscosity asphalt material, and 1-20 parts of the high-viscosity asphalt modifier is added into every 100 parts of matrix asphalt. The high-viscosity asphalt material disclosed by the invention can efficiently and durably purify main pollutants such as nitrogen oxides in automobile exhaust in a pavement temperature range no matter whether sunlight exists or not, and meanwhile, the noise pollution of urban pavements is effectively reduced, the friction force of the pavements is enhanced, the generation of water films is inhibited, and the product can be widely applied to construction of modern asphalt pavements and sponge cities.
Owner:CHINA PETROLEUM & CHEM CORP +1

Insect virus and sex pheromone microcapsule and preparation method thereof

InactiveCN112889816AEffective lureProtection inactivationBiocidePest attractantsSexual PheromonesUltraviolet lights
The invention relates to the technical field of biopesticides, in particular to an insect virus and sex pheromone microcapsule and a preparation method thereof. The preparation method of the microcapsule comprises the following steps: uniformly mixing the insect virus-containing microcapsule and the insect sex pheromone to obtain a mixture, mixing the mixture and a chitosan solution, and filtering to obtain the insect virus and sex pheromone microcapsule. The insect virus and sex pheromone microcapsule is safe and environment-friendly, can effectively attract insects, improves the insect killing efficiency, protects insect viruses from being inactivated by irradiation of sunlight, especially ultraviolet light, and prolongs the preservation time of a virus insecticide in the environment.
Owner:ZHONGKAI UNIV OF AGRI & ENG

Antibacterial formaldehyde-free UV blockboard and preparation technology thereof

The invention discloses an antibacterial formaldehyde-free UV blockboard and a preparation technology thereof. The blockboard comprises a base material, an antibacterial layer and a UV curing layer which are sequentially arranged, wherein the antibacterial layer contains formaldehyde removing and bacteria resisting microspheres; each formaldehyde removing and bacteria resisting microsphere comprises a nanometer polymer hollow microsphere of which the center is permeated by water-in-oil droplets; each water-in-oil droplet comprises bamboo vinegar liquid at the outer layer, and a sodium hydroxide water solution at the inner layer; and titanium dioxide aerosol particles are dispersed in the sodium hydroxide water solutions. According to the antibacterial formaldehyde-free UV blockboard, the bamboo vinegar liquid is capable of absorbing volatile harmful gas such as formaldehyde and has spectral sterilizing efficiency to bacteria and fungus; the sodium hydroxide water solutions at the innerlayers are capable of quickly catching formaldehyde; the titanium dioxide aerosol particles are capable of oxidizing formaldehyde molecules caught by the sodium hydroxide water solutions; the water phase and the oil phase are coordinately matched with each other to continuously clean volatile harmful gas such as formaldehyde, and thus harmful bacteria and fungus can be continuously exterminated and inhibited.
Owner:TREEZO NEW MATERIAL TECH GRP CO LTD

Preparation method of compound agent for prevention and treatment of astragalus powdery mildew

The invention discloses a preparation method of a compound agent for prevention and treatment of astragalus powdery mildew. The compound agent comprises the following components by weight: 40-60 partsof a glycolysis solution, 3-8 parts of a surfactant, 0.1-1 part of rosmarinic acid, 0.1-1 part of chitosan, and 0.02-0.04 part of tetrabutyl titanate. The invention has the beneficial effects that: because of the interaction of chitosan and tetrabutyl titanate in the above-mentioned compound agent, the compound agent can form a very thin film on astragalus leaves after use, thus prolonging the action time of the compound agent; rosmarinic acid can improve the killing power of active ingredients in the glycolysis solution to astragalus powdery mildew pathogen; the surfactant can improve the compatibility of the compound agent and astragalus leaves, all the components in the compound agent have coupling effect, can effectively inhibit the spore germination and appressorium formation of astragalus powdery mildew pathogen, and affect the morphology and structure of hypha cells, thus effectively preventing and treating astragalus powdery mildew.
Owner:金华市众鑫农业科技有限公司

Slow-release long-acting fishing net antifouling coating

The invention belongs to the technical field of antifouling coatings for fishing nets, and particularly relates to a slow-release long-acting fishing net antifouling coating comprising the following raw materials by weight: 60-65 parts of mixed resin, 16-20 parts of a slow-release antifouling agent, 3-5 parts of medium chain fatty acid triglyceride, 12-16 parts of nano calcium carbonate, 1-3 partsof gamma-aminopropyltriethoxysilane, 0.8-1.6 parts of a nitrogen-containing organic base, and 0.2-0.6 part of lignocellulose. The surface energy of a coating film of the antifouling coating is less than 20 mJ / m<2>, the coating film of the antifouling coating has a large contact angle with seawater to play an antifouling effect, wherein thiabendazole can increase the antibacterial property of a slow-release antifouling agent, cyclodextrin can prolong the action time, by rational proportioning of raw materials of the antifouling coating, the slow-release long-acting fishing net antifouling coating can effectively adhere to the surface of a fishing net to form a structurally-stable film layer which is not affected by seawater temperature and impact, the anti-corrosion and anti-fouling effectof the fishing net can be improved, meanwhile use of a copper-containing antifouling agent is avoided, and the slow-release long-acting fishing net antifouling coating is suitable for promotion.
Owner:CHAOHU XIANGYU FISHING GEAR

Flue gas denitration catalytic reactor

The invention discloses a flue gas denitration catalytic reactor. Theflue gas denitration catalytic reactor is arranged in a flue, catalytic reaction units in the catalytic reactor consist of a porousplate and a catalyst; the catalyst is arranged in an accommodating cavity enclosed by the porous plate; a connecting plate and the catalytic reaction unitsare detachably connected; an upper connecting plate and a lower connecting plate in the connecting plate are sequentially arranged in a staggered mode from the inner wall of acasing to the center; a detachable cover plate is arranged ateach ofthe tops of the catalytic reaction units;the flue gas in the flue enters an air inlet at the bottom of the casing from the flue gas denitration catalytic reactor,since the catalytic reaction unitsareconnected through the upper connecting plate and the lower connecting plate, the flue gas crosses a catalyst layer according to the internal design, undergoes a catalytic reaction throughthe catalyticreaction units, enters an upper air outlet passage corresponding to the lower connecting plate, and is discharged from the air outlet. According to the structure, the structural strength which the catalyst needs to withstand is reduced, the duration of the catalyst action is prolonged, and thus the catalyst utilization efficiency is improved.
Owner:高化学(江苏)化工新材料有限责任公司

High-viscosity asphalt material for purifying automobile exhaust and preparation method thereof

The invention discloses a high-viscosity asphalt material for purifying automobile exhaust and a preparation method of the high-viscosity asphalt material. The high-viscosity asphalt material comprises the following components in parts by weight: 100 parts of matrix asphalt; 1-20 parts of an asphalt modifier; 3-20 parts of biomass heavy oil; 5-18 parts of a thermoplastic block copolymer; 0.1-1 part of a stabilizer; and 1 to 15 parts of DOA. The asphalt modifier takes a lanthanide metal oxide as a carrier and a transition metal oxide as a catalytic active component. The high-viscosity asphalt material disclosed by the invention can efficiently and durably purify main pollutants such as nitrogen oxides in automobile exhaust in a pavement temperature range no matter whether sunlight exists or not, and meanwhile, the noise pollution of urban pavements is effectively reduced, the friction force of the pavements is enhanced, the generation of water films is inhibited, and the material can be widely applied to construction of modern asphalt pavements and sponge cities.
Owner:CHINA PETROLEUM & CHEM CORP +1

Preparation method of long-acting stable type foam dust suppressant material

The invention relates to a preparation method of a long-acting stable type foam dust suppressant material, and belongs to the technical field of the dust suppressant materials. According to a technical scheme of the invention, supercritical carbon dioxide is adopted to carry out extraction, so that thuja sutchuenensis essential oil can be effectively extracted and used as a raw material; when bubbles are generated, surfactant molecules are distributed on the surface of a liquid membrane, and the surfactant molecules are large in viscosity, thus being easy to form a surface membrane with high strength; therefore, the liquid membrane is difficult to break and the service lives of foams are also relatively long; meanwhile, the material prepared by the invention effectively reduces surface tension so as to be beneficial to the dispersion of air in liquid, prevent merger among the foams, be beneficial to the formation of micro bubble structures, generate a great amount of foam and improve efficiency of a foam dust suppressant; by reducing the surface tension of water, a contact angle between water and dust is reduced, so that an aqueous solution has relatively high wettability and adhesivity to the dust; the affinity of water to the dust is improved; and the wetting capacity and dust suppression effect of water to the dust are improved, thereby further improving the suppressing efficiency and action time-effect of the foam dust suppressant material to the dust.
Owner:雷江文

Sterilization algicide for coking sewage treatment and preparation method thereof

The invention relates to the field of water treatment agents, and particularly discloses a sterilization algicide for coking sewage treatment and a preparation method thereof. The sterilization algicide for coking sewage treatment comprises a porous load matrix and a coating layer arranged on the porous load matrix in a filling mode, wherein the coating layer comprises, in parts by weight, 10-15 parts of chitosan, and 6-8 parts of a composite beneficial bacterium agent; and the compound beneficial bacterium agent comprises one or more of a bacillus pumilus agent, an actinomycete agent, a lactobacillus fermentum agent and a lactobacillus casei agent. The preparation method comprises the preparation steps of S1, performing preliminary compounding; S2, performing secondary mixing; and S3, grinding and compounding. According to the invention, a composite system formed by the porous loading matrix and the coating layer of the beneficial bacterium agent is adopted, so that the service life of the sterilization algicide is prolonged, and good sterilization and algicide effects are achieved.
Owner:CHANGZHOU YAOS TONGDE CHEM

Self-polymerization fracturing sand modifier based on supramolecular elastomer and preparation method of self-polymerization fracturing sand modifier

ActiveCN113025303AAchieve spontaneous aggregationInhibit refluxDrilling compositionElastomerPolymer science
The invention provides a self-polymerization fracturing sand modifier based on a supramolecular elastomer and a preparation method of the self-polymerization fracturing sand modifier. The self-polymerization fracturing sand modifier is prepared by compounding 10%-50% of a supramolecular elastomer, 0.3%-4% of a plasticizer and 46%-89.7% of an alcohol ether cosolvent at room temperature. The compound system can be coated on the surface of fracturing sand in a pre-coating manner, and is carried by fracturing fluid to be pumped into a stratum. In view of the self-healing characteristic of the supramolecular elastomer, the modified fracturing sand also has spontaneous aggregation performance. After the fracturing fluid is subjected to gel breaking at the formation temperature, the supramolecular elastomer in the coating layer at the contact point of the modified fracturing sand can form a reversible physical cross-linked network structure through multiple hydrogen-bond interaction, spontaneous aggregation of the fracturing sand is achieved, and then flowback and backflow of the fracturing sand in the production process are effectively inhibited.
Owner:CHINA UNIV OF PETROLEUM (EAST CHINA)

NGF and hydroxypropyl-beta-cyclodextrin inclusion compound ophthalmic gel and preparation method thereof

The invention discloses NGF and hydroxypropyl-beta-cyclodextrin inclusion compound ophthalmic gel and a preparation method thereof.The ophthalmic gel comprises NGF, hydroxypropyl-beta-cyclodextrin and an ophthalmic gel base material, wherein the content of NGF is 30-400 micrograms / ml, the content of hydroxypropyl-beta-cyclodextrin is 10-80 g / ml, and the remaining constituent is the ophthalmic gel base material.The preparation method comprises the steps of mixing NGF, hydroxypropyl-beta-cyclodextrin and the ophthalmic gel base material with water, and conducting stirring, so that gel is formed; adjusting the pH value to 6.5-8.5, adding sufficient water, adjusting the concentration of NGF to 30-400 micrograms / ml, and stirring the mixture to be uniform, so that the NGF and hydroxypropyl-beta-cyclodextrin ophthalmic gel is obtained.The ophthalmic gel has the advantages of being good in biocompatibility, good in medicine stability, low in irritation, high in medicine atrium permeability and the like.
Owner:XIAMEN EYE CENTER OF XIAMEN UNIVERSITY CO LTD

Photoactivated implant surface decontamination sol, and preparation method and application thereof

The invention discloses photoactivated implant surface decontamination sol as well as a preparation method and application thereof, solves the problem that residual bacteria cannot be killed and extracellular polymers of the residual bacteria cannot be removed on the premise that the surface of an implant is not damaged in the prior art, and belongs to the technical field of implant infection treatment. The photoactivated implant surface decontaminating sol is prepared from the following raw materials: peroxide, oxygen-deficient titanium dioxide, an excipient and water, wherein the surface decontaminating sol comprises 1-300 mg / mL of oxygen-deficient titanium dioxide; the mass concentration of peroxide in the surface decontamination sol is greater than 0.1 and less than or equal to 40%. According to the invention, the synergistic effect of photo-thermal, photocatalysis and Fenton effect of defective titanium dioxide is applied, so that the sterilizing and decontaminating effects are obviously enhanced. The decontamination sol has the advantages of mildness, broad spectrum, no damage to normal tissues and original structures or coatings on the surfaces of the implants, capability of thoroughly cleaning the implants and the like, and provides a powerful means for decontamination and cleaning of infected implants.
Owner:SICHUAN UNIV

Preparation method and application of drug-coated balloon catheter

This application relates to the technical field of medical devices, and provides a method for preparing a drug-coated balloon catheter. The method uses the three-dimensional balloon catheter obtained by inflating treatment as a raw material, and sequentially adopts the methods of ultrasonic atomization spraying and fumigation crystallization treatment. treatment to form crystals attached to the three-dimensional balloon catheter. This preparation method can reduce the loss rate of drugs during the intervention process and ensure that more drugs are used for treatment; at the same time, it improves the release rate of drugs so that drugs can quickly act on cells Improve the retention time of the drug in the body, make the drug act on the cells for a long time, reduce the metabolic rate of the drug, promote the absorption of the drug, and achieve a long-term therapeutic effect. At the same time, the preparation method has easy-to-obtain materials, is simple and easy to operate, has clear steps, and is favorable for wide application.
Owner:融冲(深圳)生物医疗科技有限责任公司
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