50results about How to "Relieve oxidative stress" patented technology

The invention discloses a feed additive for preventing lactation-period-calf diarrhea and an application method thereof. According to the feed additive, natural astaxanthin, sodium humate, beta-hydroxyl-beta-methylbutyric acid, glutamine, xylooligosaccharide and a Chinese herbal medicine additive (agrimonia pilosa ledeb, honeysuckle, Chinese pulsatilla roots, hawthorns, pomegranate bark, talc andlicorice roots) are compounded, the balance of gastrointestinal flora of lactation-period calves is conditioned, development of gastrointestinal mucosa is promoted, the damage and influence of pathogens and unfavorable factors on the calves are reduced, digestion and absorption of nutritional ingredients are increased, the body immunity is improved, the suffered oxidation stress and oxidative damage are relieved, the anti-stress ability is improved, and therefore the aims that occurrence of lactation-period-calf diarrhea is avoided, absorption of feed nutrients is promoted, and the health level and production performance of the calves are improved are achieved.

The invention discloses low-sugar weight-losing coffee and a preparation method thereof. The low-sugar weight-losing coffee comprises the following components in percentage by weight: 30%-60% of coffee powder, 10%-30% of skim milk powder, 10%-30% of inulin, 0.6%-3% of L-carnitine, 0.1%-5% of lotus leaves, 0.1%-5% of haws, 0.1%-5% of cassia seeds, 0.1%-5% of hemp seeds, 0.1%-5% of corn stigma and 0.01%-1.0% of sucralose. The product belongs to a sugar-free low-sugar product, is smooth in taste, rich in coffee flavor and rich in taste, and has the remarkable effects of refreshing, satiety, losing weight, clearing internal heat, improving intestinal tracts and relieving fatigue. The tea is instant, convenient and fast; the low-sugar weight-losing coffee is suitable for all weight-reducing people.

The invention discloses feed for late pregnancy of sows and a feeding method. The feed is characterized by being prepared from the following components in parts by weight: 55 to 65 parts of corn, 15 to 25 parts of soybean meal, 5 to 10 parts of wheat bran, 1 to 2 parts of soybean oil, 1 to 2 parts of glucose, 0.5 to 1 part of table salt, 1 to 2 parts of mountain flour, 1 to 2 parts of dicalcium phosphate, 0.3 to 0.5 part of lysine, 0.4 to 0.8 part of threonine, 4 to 7 parts of dietary fiber, 2 to 4 parts of plant extract, 0.1 to 0.3 part of choline chloride and 3 to 4 parts of sow compound premix. According to the feed disclosed by the invention, when the seed is used for producing by comprehensively considering physiological characteristics of pregnancy, the oxidative stress of the late pregnancy of the sows can be alleviated, the rate of weak piglets and dead fetuses of the sows is reduced, the quantity of healthy piglets is increased and the production benefits are easy to improve;the oxidative stress of the late pregnancy can be alleviated and the pregnancy metabolism is alleviated at maximum, so that the oxidative stress of the late pregnancy of the sows is alleviated and thefetal birth health and uniformity are ensured; furthermore, certain antibiotics are replaced with the plant extract in the product, so that the addition of medicines in the feed is greatly reduced.

The present invention provides a premix for preventing and treating fatty liver of dairy cattle in a perinatal period and a related application thereof. The premix simultaneously contains a certain amount of ruminal choline and selenium, creatively utilizes a combination of the two materials to have a double protection function for liver, groundbreakingly realizes a synergic effect of the two materials added in the premix at the same time, is prefect in liver protection, antioxidant and lactating performances of the dairy cattle in the perinatal period, and realizes an one-plus-one-is-greater-than-two effect.

The invention provides a pharmaceutical composition for preventing and treating chicken coccidiosis and an application thereof. The pharmaceutical composition contains lactobacillus plantarum P8 and chlorogenic acid, wherein the biological preservation number of the lactobacillus plantarum P8 is CGMCC No. 6312. According to the invention, immune imbalance and intestinal oxidative damage of broilerchickens caused by coccidiosis infection can be relieved; the content of anti-inflammatory factors can be significantly improved, and the content of pro-inflammatory factors can be reduced, so the body immunity tends to be normal; meanwhile, the pharmaceutical composition provided by the invention can also relieve intestinal barrier damage, repair intestinal structures and enhance the resistanceof intestinal mucosa, is beneficial for intestinal health, can completely or partially replace chemically synthesized anticoccidial drugs and antibiotic products, has no drug residues and pollution, and is green, safe and environmentally-friendly.

The invention discloses a fattening pig premix additive capable of improving meat quality and a preparation method thereof, and belongs to the field of feed additives. The feed is prepared from the following raw materials according to every 2000 parts by weight: 30-90 parts of herba gracilariae asiaticae, 30-90 parts of common seepweed herb, 50-80 parts of ulva pertusa kjellm, 40-100 parts of fructus crataegi, 40-120 parts of radix astragali, 40-120 parts of serine, 40-120 parts of glycine, 50-110 parts of leucine, 50-110 parts of isoleucine, 100-300 parts of soybean oil, 200-400 parts of linseed oil and a carrier. Only a trace of the premix additive is added to the feed, a pork color, drop loss, tenderness, intramuscular fat content and muscle fiber type compositions can be effectively improved, and a pork flavor, a mouthfeel and a nutritive value are improved. The premix additive is safe and no side effects in source of raw materials, and pollution-free to an environment.

The present invention provides nanoformulations for topical and systemic fat reduction and uses thereof. The nano preparation consists of an oil phase and a water phase. The oil phase is selected from triglyceride and other membrane material components, an oxidative stress inhibitor vitamin E, an endoplasmic reticulum UPR pathway inhibitor and the like, and the water phase is selected from a vitamin C deionized water solution and the like. According to the nano preparation, the endoplasmic reticulum stress inhibitor is entrapped in the carrier containing the oxidative stress inhibitor, so that the fat differentiation of precursor cells and the oxidative stress and the endoplasmic reticulum stress which are necessary in the maturation process of fat cell accumulated lipid are weakened, the new fat source is greatly reduced, and the overgrowth of the existing fat cells is inhibited; the purpose of efficient and safe slimming is achieved. Different purposes of local and/or systemic fat reduction can be realized due to different administration modes, administration sites and administration dosages. In addition, the traditional Chinese medicine also has a certain effect on preventing/treating fatty liver. The method is reasonable in design, easy to prepare, safe, efficient and easy to popularize.

The invention belongs to food and particularly relates to application of a ganoderma lucidum polysaccharide compound in relieving toxicity of cyclophosphamide (CYP). The ganoderma lucidum polysaccharide compound comprises ganoderma lucidum polysaccharide and waxy corn starch, wherein the mass ratio of the ganoderma lucidum polysaccharide to the waxy corn starch is 1:4. The prepared ganoderma lucidum polysaccharide and corn starch large-particle compound has functions of effectively relieving oxidation stress and liver injury caused by the CYP. The compound shows a certain anti-digestion characteristic due to physical functions of corn starch and ganoderma lucidum polysaccharide, overcomes defects of in-vivo digestion of ganoderma lucidum polysaccharide, and effectively improves the utilization rate and biotransformation rate of the ganoderma lucidum polysaccharide.

The invention discloses an immunoenhancer for a pregnant sow. The immunoenhancer is prepared from the following components in parts by weight: 15-25 parts of Chinese herbal medicine extract, 4-8 parts of fish meal, 2-4 parts of stone powder, 2-4 parts of calcium monohydrogenphosphate, 5-9 parts of glucose, 1.5-2.5 parts of lysine, 1.5-2.5 parts of methionine, 1.5-2.5 parts of threonine, 1.5-2.5 parts of arginine, 2-4 parts of beta-hydroxyl-beta-methylbutyric acid, 2-4 parts of acidifier, 2-4 parts of enzyme preparation, 1.5-2.5 parts of vitamin complex, 3-5 parts of probiotic complex and 35-40 parts of starch accessory, wherein the Chinese herbal medicine extract is prepared by extracting pulp of cornus, dark plum fruit, medicated leaven, ephedra herb, coptis root, datura flower, cassia seeds, wrinkled gianthyssop herb, rhizoma chuanxiong, atratylodes rhizome and cinnamon in a weight ratio of 10:10:15:10:5:10:5:10:5:10:10. The immunoenhancer disclosed by the invention can enhance the reproductive performance and immunity of a pregnant sow and improve the absorption function of intestinal mucosa so as to realize a function of preventing and treating diseases and provide nutrition to promote the growth and development of piglets.

The invention discloses application of quercetin in preparation of a medicine for treating intervertebral disc nucleus pulposus degeneration. Tests prove that quercetin has an obvious effect of protecting nucleus pulposus cells from being damaged. In a rat nucleus pulposus cell apoptosis model of 100microM of TBHP, quercetin can obviously weaken nucleus pulposus cell damage caused by TBHP and maintain normal forms and functions of nucleus pulposus cells; quercetin has low toxicity to nucleus pulposus cells, and almost has no cytotoxicity within 200microM; quercetin can be used for remarkably relieving oxidative stress, degeneration and apoptosis of TBHP-induced nucleus pulposus cells of rats; according to the invention, new application of quercetin is developed, the use value of quercetin is improved, and theoretical support is provided for application of quercetin in preparation of drugs for preventing intervertebral disc degeneration.

The invention relates to a feed capable of improving semen quality of breeder cocks. Sodium butyrate, compound organic trace elements and arginine are added in the formula of the feed so as to synergistically take an effect, so that, the feed is capable of significantly improving semen quality of breeder cocks; and the feed is especially capable of significantly improving semen quality of the breeder cocks in the middle and late growth stages as well as subsequently enhancing reproductive performance of the breeder cocks so as to significantly improve fertilization rate of setting eggs in themiddle and late growth stages. The feed is also capable of prolonging service lives of the breeder cocks as well as reducing investment in breeding cocks to a certain extent, thereby decreasing cost and increasing economic benefits.

A medicine composition for treating renal interstitial fibrosis is disclosed. Effective components of the composition are rosiglitazone or a pharmaceutically acceptable salt thereof and puerarin. Thepharmaceutically acceptable salt of the rosiglitazone is one of rosiglitazone hydrochloride or rosiglitazone maleate or a combination thereof. The composition has significant antifibrosis activity, anti-inflammatory activity and antioxidation stress activity which are superior to those of a single medicine, and can significantly improve renal interstitial fibrosis.

The invention relates to an antibacterial, anti-inflammatory and antioxidant carex meyeriana extract as well as a preparation method and application thereof, and belongs to the field of phytochemistry. The preparation method comprises the following steps of crushing carex meyeriana, adding 50-95% ethanol in an amount which is 8-12 times the volume mass of the carex meyeriana, soaking for 20-60 minutes, carrying out reflux extraction twice for 20-60 minutes each time, filtering, merging filtrates, concentrating and drying to obtain the carex meyeriana extract. The invention discloses application of the antibacterial, anti-inflammatory and antioxidant carex meyeriana extract in preparation of an antibacterial agent, an anti-inflammatory agent or an antioxidant. The antibacterial, anti-inflammatory, antioxidant and carex meyeriana extract disclosed by the invention is derived from cyperaceae Carex Linn. plant carex meyeriana, is an ethanol extract of whole grass of carex meyeriana, and has good antibacterial, anti-inflammatory and antioxidant effects; and the extract has an inhibiting effect on gram-negative bacteria, gram-positive bacteria, fungus typical pathogenic bacteria such asstaphylococcus aureus, escherichia coli, pseudomonas aeruginosa, candida albicans and the like.

The invention relates to application of piceatannol-3'-O-beta-D-glucopyranoside in treatment of small intestine mucosa injury and intestinal inflammatory cell infiltration caused by ischemia reperfusion. Experimental results show that by virtue of the piceatannol-3'-O-beta-D-glucopyranoside, the yield of malondialdehyde (MDA) and the activity of myeloperoxidase (MPO) in intestinal tissues after ischemia/reperfusion can be remarkably reduced, the expression level of tumor necrosis factor-alpha (TNF-alpha) can be reduced, the expression level of endothelial nitric oxide synthase (eNOS) can be increased, the activity of total-superoxide dismutase (T-SOD) can be remarkably improved, and intestinal interstitial hemorrhage and small intestine mucosa defect are relieved. The piceatannol-3'-O-beta-D-glucopyranoside can effectively treat the small intestine ischemia reperfusion injury, and a basis is provided for application of the piceatannol-3'-O-beta-D-glucopyranoside in treatment of small intestine ischemia reperfusion related diseases.

The invention provides an application of lactobacillus rhamnosus LRa05 in preparation of a preparation for improving irritable bowel syndrome. The lactobacillus rhamnosus LRa05 freeze-dried powder provided by the invention has a remarkable curative effect on the irritable bowel syndrome, and can be used for reducing serum endotoxin, reducing proinflammatory factors, increasing the level of anti-inflammatory factors, relieving oxidative stress and adjusting intestinal flora disorder, so that the intestinal flora is healthy. The lactobacillus rhamnosum LRa05 freeze-dried powder product provided by the invention is simple to prepare and suitable for large-scale production, has the characteristics of simple treatment, high remission rate, no toxic or side effect and the like as an auxiliary medicine of IBS, and is relatively high in practicability.