21results about How to "Novel preparation method" patented technology

The invention belongs to the field of polymer preparation, and particularly relates to a preparation method of high-toughness NDI-based fluorescent polyurea, the polyurea takes NDI, polyether amine, TEPA and IPDI as raw materials, the NDI, the polyether amine and the TEPA can construct a main chain under mild conditions by utilizing rapid reaction of isocyanate and amino, the main chain is crosslinked by utilizing reaction of diisocyanate and secondary amine, and the high-toughness NDI-based fluorescent polyurea is prepared. A gradient energy dissipation mechanism is formed by the difference of breaking energy of the hydrogen bond and the covalent bond, the toughness of the material is greatly improved, and the hydrogen bond and the covalent bond are crosslinked to limit'movement 'of a planar rigid conjugated structure, so that non-radiative transition is weakened, radiative transition is enhanced, and fluorescence characteristic enhancement is facilitated. The preparation method of the high-toughness fluorescent polyurea is novel, the prepared polyurea has ultrahigh toughness and fluorescence characteristics, the selected raw materials are low in cost, and the high-toughness fluorescent polyurea has wide market prospects. Steps are simple, operation is convenient, and practicability is high.

The invention relates to the technical field of preparation of lithium ion sieve adsorbents, in particular to a preparation method of a high-dispersion manganese lithium ion sieve adsorbent and a precursor thereof. The method comprises the following steps: continuously dropwise adding an aqueous solution of alkali into a mixed aqueous solution of a manganese source and a dispersant, adjusting the pH value, adding an oxidant, carrying out solid-liquid separation and drying to obtain Mn3O4 powder, carrying out ball milling, suction filtration and drying on the Mn3O4 powder and a lithium source, roasting to obtain Li1. 33Mn1. 67O4 lithium ion sieve precursor powder, mixing the Li1. 33Mn1. 67O4 lithium ion sieve precursor powder and a binder, molding, and drying to obtain Li1. 33Mn1. 67O4 particles, and carrying out acid washing to obtain the H1. 33Mn1. 67O4 lithium ion sieve. The method has the advantages of low cost, simple process, greenness, energy conservation and the like, and can be well applied to industrial production.

A semiconductor device (200) is provided with: an oxide (230) on a substrate; a first conductor (242a1) and a second conductor (242b1) spaced apart from each other on the oxide; a third conductor (242a2) in contact with a portion of the top surface of the first conductor; a fourth conductor (242b2) in contact with a part of the top surface of the second conductor; first insulators (271a, 271b) disposed on the third conductor and the fourth conductor and having an opening overlapping a region between the third conductor and the fourth conductor; a second insulator (255) disposed in the opening of the first insulator and in contact with the other part of the top surface of the first conductor, the other part of the top surface of the second conductor, the side surface of the third conductor, and the side surface of the fourth conductor; a third insulator (250) disposed in the opening of the first insulator and in contact with the top surface of the oxide, the side surface of the first conductor, the side surface of the second conductor, and the side surface of the second insulator; and a fifth conductor disposed on the third insulator in the opening of the first insulator and having a region overlapping the oxide via the third insulator, in which a distance (L2) between the first conductor and the second conductor is smaller than a distance (L1) between the third conductor and the fourth conductor.

Provided is a semiconductor device capable of achieving miniaturization or high integration. The semiconductor device includes a first conductor and a second conductor spaced apart from each other on an oxide, a third conductor in contact with a portion of a top surface of the first conductor, and a fourth conductor in contact with a portion of a top surface of the second conductor, the first insulator is arranged on the third conductor and the fourth conductor and is provided with an opening between the third conductor and the fourth conductor; the first insulator is arranged in the opening of the first insulator and is connected with the other part of the top surface of the first conductor and the other part of the top surface of the second conductor; a second insulator in contact with a side surface of the third conductor and a side surface of the fourth conductor; a third insulator in contact with a top surface of the oxide and side surfaces of the first conductor, the second conductor, and the second insulator; and a fifth conductor disposed on the third insulator. A distance between the first conductor and the second conductor is smaller than a distance between the third conductor and the fourth conductor, the second insulator includes a first layer and a second layer on the first layer, the first layer includes a nitride insulator, and the second layer includes an oxide insulator.

A liposome enzyme nanoreactor and its preparation method and application in anti-tumor treatment belong to the field of bio-nanomedicine technology. The outer layer of the liposome enzyme nanoreactor is a liposome with good biocompatibility, and the interior contains glucose oxidase and horseradish peroxidase. The liposome enzyme nanoreactor causes glucose oxidase and horseradish peroxidase to undergo a cascade reaction after compartmentalization, which can effectively inhibit tumor growth in vivo and in vitro by inhibiting tumor nutrient supply and generating highly cytotoxic hydroxyl free radicals (·OH), leading to cancer cell apoptosis. Enzyme co-compartmentalization in the liposome increases the intermediate product hydrogen peroxide (H 2 O 2 ) and the local concentration of acid, further accelerating the second step of the horseradish peroxidase-mediated reaction of producing cytotoxic OH, so that the entire cascade reaction reaches a higher reaction efficiency. The liposome enzyme nanoreactor disclosed in the present invention has a highly efficient anti-tumor ability and has clinical potential for treating tumors.

The invention relates to an oxide semiconductor layer, a semiconductor device, and a method of manufacturing the semiconductor device. Provided is an oxide semiconductor layer that can be used in a semiconductor device having good electrical characteristics. In addition, the invention provides a semiconductor device and a manufacturing method of the semiconductor device. The present invention is an oxide semiconductor layer containing indium formed on a substrate, the oxide semiconductor layer being formed so as to be parallel or substantially parallel to the surface of the substrate, the oxide semiconductor layer having a first region, a second region on the first region, and a third region on the second region, the first region is substantially vertically located at 0 nm or more and 3 nm or less from a surface on which the oxide semiconductor layer is to be formed, and bright spots arranged in layers in a direction parallel to the surface on which the oxide semiconductor layer is to be formed are confirmed in each of the first region, the second region, and the third region when a cross-section of the oxide semiconductor layer is observed by a transmission electron microscope.

The invention discloses an efficient preparation method of mivacurium chloride, which comprises the following steps: (1) reacting (E)-octyl-4-ene-1, 8-diacid, 3-chloro-1-bromopropane, alkali, cesium chloride and a reaction solvent at the temperature of 30-100 DEG C for 6-15 hours; cooling after the reaction is completed, adding water and an organic solvent for extraction, and separating liquid; washing an organic phase with water, and concentrating under reduced pressure to obtain (E)-octyl-4-ene-1, 8-diacid di-(3-chloropropyl) ester; and (2) carrying out a reaction on the (E)-octyl-4-ene-1, 8-diacid di-(3-chloropropyl) ester, the (R)-(+)-5 '-methoxylaudanin, sodium iodide, potassium carbonate and the reaction solvent at the temperature of 50-85 DEG C for 18-40 hours, and carrying out post-treatment to obtain mivacurium chloride. The method disclosed by the invention is novel, avoids the use of thionyl chloride and a condensing agent, is more environment-friendly, is friendly to the environment and an operator, and is mild in reaction condition, high in reaction efficiency, high in yield, low in equipment requirement and simple to operate; the method has the advantages of cheap and easily available reaction raw materials and reagents, few by-products, simple purification and easy operation, and is suitable for preparation of human bulk drugs with high purity and safety requirements, and the purity of the obtained mivacurium chloride is higher than 99.5%.

The present invention belongs to the technical field of lithium batteries, and discloses a lithium alloy negative electrode with a reserved space and an integrated conductive skeleton and a preparation method thereof. A lithium-rich alloy layer is provided at the lower layer of the alloy skeleton layer, and the lithium-rich alloy layer contains a three-dimensional skeleton formed by a lithium solid solution / intermetallic compound. The upper layer of the lithium alloy negative electrode is a reserved space formed by the three-dimensional alloy skeleton remaining after the lithium single phase is selectively removed by an organic solvent and the gaps between the skeletons. The skeleton in the surface reserved space and the skeleton in the lithium alloy are both three-dimensional integrated skeleton structures formed in situ by lithium solid solution or intermetallic compound, which significantly improve the cycle performance of the battery. At the same time, the thickness of the reserved space skeleton layer can be strictly controlled by the concentration of the organic solution and the immersion time, which is suitable for rapid preparation by the roll-to-roll method, and is convenient for commercial mass production applications.

The invention belongs to the technical field of preparation methods of flocculants, and relates to a preparation method of a cationic organic polymeric flocculant. The preparation method comprises the following steps: sequentially reacting trans-1, 4-dichloro-2-butene with an intermediate product 1 and tridecafluorooctanol twice to obtain a disilane gemini quaternary ammonium salt intermediate and trans-1, 4-bis (tridecafluorooctyloxy) butyl-2-ene, and carrying out initiated polymerization on the disilane gemini quaternary ammonium salt intermediate and trans-1, 4-bis (tridecafluorooctyloxy) butyl-2-ene and acrylamide to obtain the cationic organic polymeric flocculant. Quaternary ammonium salt contained in the water is adsorbed on suspended particles with negative charges through electrostatic interaction, so that the suspended particles are subjected to coagulation, flocculation and sedimentation; silicon hydroxyl generated by hydrolysis of a siloxane structure can be combined with inorganic matters, so that the settling efficiency is improved; the fluorine-containing hydrophobic group enhances the interaction between polymer molecular chains through the hydrophobic association effect, enhances the adsorption bridging effect, and enhances the flocculation effect. The prepared flocculant has the advantages of being simple in preparation process, low in cost, high in flocculation efficiency and the like, and efficient and economical flocculation operation can be conveniently achieved.

The invention provides conductive ceramic and a preparation method and application thereof.The conductive ceramic comprises a conductive ceramic matrix and a ceramic coating arranged on the surface of the conductive ceramic matrix, the conductive ceramic matrix comprises metal elements, and the ceramic coating comprises a bottom layer and a surface layer which are sequentially stacked on the surface of the conductive ceramic matrix; the bottom layer comprises a silicon-containing material, a boron-containing material and a phosphate of at least one metal element, and the surface layer comprises a glass phase and a metal complex. The ceramic coating on the surface of the conductive ceramic can relieve the thermal mismatch effect, is high in oxidation resistance and has the crack self-healing capability, so that the service life of the conductive ceramic can be prolonged.

The application discloses a kind of buried copper block circuit board and its manufacturing method, the manufacturing method includes: the two outer layers of core plate are copper foil layer, and window position A is provided on the non-line area of one outer layer;Core plate is double-sided inner layer pattern production, to make inner layer circuit pattern and pad on the two outer layers of core plate respectively, and make a plurality of flow blockings on one outer layer of core plate, which are surrounded outside window position A;The insulating layer is covered on the two outer layers of core plate, and window position B is provided on the insulating layer adjacent to flow blocking, which is opposite to window position A;Based on window position, insulating layer and core plate are windowed;After the copper block gap with rough surface is placed in window, it is compressed and handled, and in the process of compression, the flow of colloid in window is controlled by flow blocking, so that copper block is firmly combined with insulating layer and core plate together.The manufacturing method is simple and reasonable, easy to implement, the reliability and stability of the obtained circuit board product are high, and the market demand is met.

The invention relates to a manufacturing method of a semiconductor device. Provided is a semiconductor device having a high operating speed. A method of manufacturing a semiconductor device includes: forming a first coating film on a first insulator and a second coating film on the first coating film; removing a part of the second coating film to form a first layer; forming a second layer by removing a portion of the first coating film using the first layer as a mask; performing a heat treatment process; forming a first oxide semiconductor so as to cover the top surface of the first insulator, the side surfaces of the second layer, and the side surfaces and the top surface of the first layer; processing the first oxide semiconductor by anisotropic etching to form a second oxide semiconductor in contact with a side surface of the second layer; removing the first layer; the second layer is removed to expose a side surface of the second oxide semiconductor covered by the second layer.

The invention belongs to the technical field of phosphorescent materials, and particularly relates to a circularly polarized room-temperature phosphorescent material based on marine polysaccharides and preparation and application thereof.The circularly polarized room-temperature phosphorescent material based on marine polysaccharides is prepared by the steps that 4-(4-bromophenyl)-pyridine and methyl iodide are dissolved in absolute ethyl alcohol, a reflux reaction is performed to prepare bromophenyl pyridinium, and the bromophenyl pyridinium is dissolved in absolute ethyl alcohol; dissolving the chiral marine polysaccharide lambda-type carrageenan containing the negative sulfate radical group and an achiral phosphorescent color body bromophenyl pyridinium containing the positive pyridine group in deionized water, performing ultrasonic heating until the solution is clear, and then gradually cooling and self-assembling to form a lambda-type carrageenan and bromophenyl pyridinium suspension; finally, the lambda-type carrageenan and bromophenylpyridinium suspension is subjected to vacuum drying, the circularly polarized room-temperature phosphorescent thin film material based on the marine polysaccharide is obtained, the material property is stable, the circularly polarized room-temperature phosphorescent thin film material can be applied to phosphorescent digital encryption, optical anti-counterfeiting and the like, the preparation method is simple and novel, the raw material source is wide, the cost is low, and industrial production is facilitated. The method has important significance for designing and preparing CP-RTP materials based on natural macromolecules.

The present invention is a method for preparing a hierarchical pore high entropy metal-nitrogen doped carbon catalyst. The method comprises the following steps: (1) placing reactants, SiO2 microspheres and grinding balls in a ball mill, washing with ethanol, and vacuum drying to obtain a SiO2@high entropy ZIFs complex; (2) placing the SiO2@high entropy ZIFs complex obtained in the previous step in a quartz boat, maintaining it at 800-1100°C for 1-3h, then soaking it with acid or alkali to remove the SiO2 template, and washing it with ethanol and vacuum drying to obtain a hierarchical pore high entropy metal-nitrogen doped carbon catalyst. The present invention has great potential application value in the fields of photothermal catalysis and synergistic catalysis, and broadens its application in the field of catalysis.

The invention provides a preparation method of bis (4-tert-butylphenyl) iodonium bis (perfluorobutane sulfonyl) imine, which comprises the following steps: in the environment of shielding gas, mixing and stirring bis (perfluorobutane sulfonyl) imine, alkali, an organic solvent and ultrapure water, then adding bis (4-tert-butylphenyl) iodine chloride for reaction, and after the reaction is finished, filtering to obtain the bis (4-tert-butylphenyl) iodonium bis (perfluorobutane sulfonyl) imine. And carrying out post-treatment to obtain the bis (4-tert-butylphenyl) iodonium bis (perfluorobutane sulfonyl) imine. The preparation method has the beneficial effects that the preparation method is simple, the reaction system is mild, the selectivity is good, the total preparation cost is low, and the yield is high.

The application discloses an eudesmane type sesquiterpenoid compound and a preparation and application thereof, and obtains a novel eudesmane type sesquiterpenoid compound linderasin J from the rhizome of Lindera aggregata by simple processes such as organic solvent extraction and column chromatography separation, and the preparation method is simple and rapid, and the obtained compound has high purity. The eudesmane type sesquiterpenoid compound has good in-vitro anti-inflammatory activity, can effectively inhibit the expression of inflammatory factors IL-1 β , IL-6, iNOS and COX-2, and can be applied in the research and development of anti-inflammatory drugs. The structure optimization of the compound as a lead has important significance for the research and development of new anti-inflammatory drugs.

The present invention relates to a nano-Fe 0 @Fe3O4 core-shell structure material and its preparation method and application. The method comprises the following steps: firstly preparing a mixture of a strong base and a strong reducing agent and an iron salt solution, then adding the mixture of the strong base and the strong reducing agent to the iron salt solution, and continuously stirring to obtain nano zero-valent iron (Fe 0 ) suspension, and then heating the nano zero-valent iron suspension to 80°C, maintaining constant temperature and stirring continuously, after sufficient reaction, obtaining black solid particles, separating the generated black solid particles by magnetic separation, and finally washing with deionized water three times, and drying with low-temperature blast air to obtain nano Fe 0 @Fe3O4 core-shell structure material. The nano-Fe prepared by the present invention 0 @Fe3O4 core-shell structure material can effectively activate persulfate to degrade organic pollutants in water, and better solve the problems of nano zero-valent iron being easily oxidized in practical applications and difficulty in maintaining activation performance. At the same time, compared with the prior art, the nano Fe 0 The preparation method of the Fe3O4 core-shell structure material has the advantages of novelty, easy availability of required raw materials, simple process, low cost, etc. 0 @Fe3O4 core-shell structure materials have good economic and environmental benefits.

The application belongs to the field of polymer preparation, and particularly relates to a preparation method of polyurea with a stimulating fluorescent response. H ), the fluorescent functional monomer (ON H ) is constructed by the reaction of epoxy resin and amino, and the phthalic acid group is suspended on the main chain by the reaction of ON and diisocyanate, so that the phthalic acid polymer is formed in the material, the structure or state of the phthalic acid polymer changes under different environments due to the different states of the carboxyl group under different pH values and the characteristic that the carboxyl group can form a coordination action with metal ions, the fluorescent characteristics change, and the fluorescent color changes from yellow-green to blue with the increase of the pH value. The preparation method of the polyurea with the stimulating fluorescent response is novel, the prepared polyurea has the stimulating fluorescent response characteristics, and has a wide market prospect. The steps are simple, the operation is convenient, and the practicability is high.

The invention discloses a ceramic filter tube catalyst as well as a preparation method and application thereof. The preparation method comprises the following steps: adding a carrier into water, adding a precursor of an active component while stirring, and continuously stirring to obtain a mixture; adding acid to adjust the pH value of the mixture to 4.0-4.5, and then adding a dispersing agent to adjust the pH value to 8.5-9.5; grinding the mixture until the D50 particle size of the mixture is 40-300nm, and then diluting the mixture with a dispersing agent solution to obtain diluted steeping liquor; soaking a ceramic filter tube in the diluted steeping liquor, and then drying and roasting to obtain the ceramic filter tube catalyst. The ceramic filter tube catalyst disclosed by the invention has a nitrogen oxide selective catalytic reduction (SCR) function, the preparation method is novel and simple to implement, uniform distribution of catalytic components on a carrier layer is realized by regulating and controlling pH, the dosage of catalytic active components is reduced, and the use cost is reduced.

The present invention belongs to the technical field of hydroxide exchange membrane fuel cells and water electrolysis, and in particular to a preparation method of a Ru-embedded TiO2 lattice-rich heterojunction interface hydrogen hydroxide precipitation electrocatalyst, comprising: dissolving 2-aminoterephthalic acid in ethanol and N,N-dimethylformamide, adding ruthenium salt, ultrasonicating under room temperature, adding isopropyl titanate after complete dissolution, and obtaining Ru-doped NH2-MIL-125(Ti) metal organic framework through a hydrothermal strategy. Further adding ruthenium salt to make Ti in the Ru-doped NH2-MIL-125(Ti) metal organic framework 4+ With Ru 3+ Metal cation exchange, by controlling the temperature and time of carbonization, Ru single atoms and reduced Ru metal clusters can be better embedded in the TiO2 lattice to form a rich heterojunction interface. In addition, there are a large number of Ru-Ti bonds at the heterojunction interface, which increases the number of active sites, ensures the effective transfer of electrons from Ti to Ru, and gives the Ru active sites a low metallic valence state.

The invention belongs to the technical field of fluorescence and electrochemistry, and particularly discloses a target cycle fluorescence-electrochemical double-signal aptamer sensor for detecting lead ions and a preparation method and application thereof.The preparation method of the aptamer sensor comprises the steps that fluorescent nanoclusters and gold magnetic nanoparticles are prepared and coupled with Apt and ssDNA respectively, and the aptamer sensor is obtained; constructing a fluorescence detection system; synthesizing Au-MoOx as an enhancement substrate for modifying the surface of the working electrode, amplifying an electrochemical signal and providing a coupling site for eDNA; and synthesizing an S1-S2 cross-linked substance, H1-Ag NCs and H2-Ag NCs, and constructing an electrochemical detection system with the modified electrode. In the aptamer sensor, Apt is separated from double strands by specifically capturing Pb < 2 + >, and RecJf enzymolysis is triggered, so that Pb < 2 + > is recycled and fluorescent substances are released; after magnetic separation, ssDNA separated from double strands is hybridized with S1, released S2 serves as a secondary target substitute and enters an electrochemical detection system, and DPV signals provided by DNA-Ag NCs synthesized in advance are further amplified in the HCR process; pb < 2 + > detection is realized according to changes of a fluorescence signal and an electrochemical signal, and specific, sensitive and rapid detection of Pb < 2 + > can be effectively realized.