9results about How to "Novel preparation method" patented technology

The invention belongs to the field of polymer preparation, and particularly relates to a preparation method of high-toughness NDI-based fluorescent polyurea, the polyurea takes NDI, polyether amine, TEPA and IPDI as raw materials, the NDI, the polyether amine and the TEPA can construct a main chain under mild conditions by utilizing rapid reaction of isocyanate and amino, the main chain is crosslinked by utilizing reaction of diisocyanate and secondary amine, and the high-toughness NDI-based fluorescent polyurea is prepared. A gradient energy dissipation mechanism is formed by the difference of breaking energy of the hydrogen bond and the covalent bond, the toughness of the material is greatly improved, and the hydrogen bond and the covalent bond are crosslinked to limit'movement 'of a planar rigid conjugated structure, so that non-radiative transition is weakened, radiative transition is enhanced, and fluorescence characteristic enhancement is facilitated. The preparation method of the high-toughness fluorescent polyurea is novel, the prepared polyurea has ultrahigh toughness and fluorescence characteristics, the selected raw materials are low in cost, and the high-toughness fluorescent polyurea has wide market prospects. Steps are simple, operation is convenient, and practicability is high.

The invention discloses an efficient preparation method of mivacurium chloride, which comprises the following steps: (1) reacting (E)-octyl-4-ene-1, 8-diacid, 3-chloro-1-bromopropane, alkali, cesium chloride and a reaction solvent at the temperature of 30-100 DEG C for 6-15 hours; cooling after the reaction is completed, adding water and an organic solvent for extraction, and separating liquid; washing an organic phase with water, and concentrating under reduced pressure to obtain (E)-octyl-4-ene-1, 8-diacid di-(3-chloropropyl) ester; and (2) carrying out a reaction on the (E)-octyl-4-ene-1, 8-diacid di-(3-chloropropyl) ester, the (R)-(+)-5 '-methoxylaudanin, sodium iodide, potassium carbonate and the reaction solvent at the temperature of 50-85 DEG C for 18-40 hours, and carrying out post-treatment to obtain mivacurium chloride. The method disclosed by the invention is novel, avoids the use of thionyl chloride and a condensing agent, is more environment-friendly, is friendly to the environment and an operator, and is mild in reaction condition, high in reaction efficiency, high in yield, low in equipment requirement and simple to operate; the method has the advantages of cheap and easily available reaction raw materials and reagents, few by-products, simple purification and easy operation, and is suitable for preparation of human bulk drugs with high purity and safety requirements, and the purity of the obtained mivacurium chloride is higher than 99.5%.

The present invention belongs to the technical field of lithium batteries, and discloses a lithium alloy negative electrode with a reserved space and an integrated conductive skeleton and a preparation method thereof. A lithium-rich alloy layer is provided at the lower layer of the alloy skeleton layer, and the lithium-rich alloy layer contains a three-dimensional skeleton formed by a lithium solid solution / intermetallic compound. The upper layer of the lithium alloy negative electrode is a reserved space formed by the three-dimensional alloy skeleton remaining after the lithium single phase is selectively removed by an organic solvent and the gaps between the skeletons. The skeleton in the surface reserved space and the skeleton in the lithium alloy are both three-dimensional integrated skeleton structures formed in situ by lithium solid solution or intermetallic compound, which significantly improve the cycle performance of the battery. At the same time, the thickness of the reserved space skeleton layer can be strictly controlled by the concentration of the organic solution and the immersion time, which is suitable for rapid preparation by the roll-to-roll method, and is convenient for commercial mass production applications.

The invention provides conductive ceramic and a preparation method and application thereof.The conductive ceramic comprises a conductive ceramic matrix and a ceramic coating arranged on the surface of the conductive ceramic matrix, the conductive ceramic matrix comprises metal elements, and the ceramic coating comprises a bottom layer and a surface layer which are sequentially stacked on the surface of the conductive ceramic matrix; the bottom layer comprises a silicon-containing material, a boron-containing material and a phosphate of at least one metal element, and the surface layer comprises a glass phase and a metal complex. The ceramic coating on the surface of the conductive ceramic can relieve the thermal mismatch effect, is high in oxidation resistance and has the crack self-healing capability, so that the service life of the conductive ceramic can be prolonged.

The application discloses a kind of buried copper block circuit board and its manufacturing method, the manufacturing method includes: the two outer layers of core plate are copper foil layer, and window position A is provided on the non-line area of one outer layer;Core plate is double-sided inner layer pattern production, to make inner layer circuit pattern and pad on the two outer layers of core plate respectively, and make a plurality of flow blockings on one outer layer of core plate, which are surrounded outside window position A;The insulating layer is covered on the two outer layers of core plate, and window position B is provided on the insulating layer adjacent to flow blocking, which is opposite to window position A;Based on window position, insulating layer and core plate are windowed;After the copper block gap with rough surface is placed in window, it is compressed and handled, and in the process of compression, the flow of colloid in window is controlled by flow blocking, so that copper block is firmly combined with insulating layer and core plate together.The manufacturing method is simple and reasonable, easy to implement, the reliability and stability of the obtained circuit board product are high, and the market demand is met.

The application discloses an eudesmane type sesquiterpenoid compound and a preparation and application thereof, and obtains a novel eudesmane type sesquiterpenoid compound linderasin J from the rhizome of Lindera aggregata by simple processes such as organic solvent extraction and column chromatography separation, and the preparation method is simple and rapid, and the obtained compound has high purity. The eudesmane type sesquiterpenoid compound has good in-vitro anti-inflammatory activity, can effectively inhibit the expression of inflammatory factors IL-1 β , IL-6, iNOS and COX-2, and can be applied in the research and development of anti-inflammatory drugs. The structure optimization of the compound as a lead has important significance for the research and development of new anti-inflammatory drugs.

The application belongs to the field of polymer preparation, and particularly relates to a preparation method of polyurea with a stimulating fluorescent response. H ), the fluorescent functional monomer (ON H ) is constructed by the reaction of epoxy resin and amino, and the phthalic acid group is suspended on the main chain by the reaction of ON and diisocyanate, so that the phthalic acid polymer is formed in the material, the structure or state of the phthalic acid polymer changes under different environments due to the different states of the carboxyl group under different pH values and the characteristic that the carboxyl group can form a coordination action with metal ions, the fluorescent characteristics change, and the fluorescent color changes from yellow-green to blue with the increase of the pH value. The preparation method of the polyurea with the stimulating fluorescent response is novel, the prepared polyurea has the stimulating fluorescent response characteristics, and has a wide market prospect. The steps are simple, the operation is convenient, and the practicability is high.

The present invention belongs to the technical field of hydroxide exchange membrane fuel cells and water electrolysis, and in particular to a preparation method of a Ru-embedded TiO2 lattice-rich heterojunction interface hydrogen hydroxide precipitation electrocatalyst, comprising: dissolving 2-aminoterephthalic acid in ethanol and N,N-dimethylformamide, adding ruthenium salt, ultrasonicating under room temperature, adding isopropyl titanate after complete dissolution, and obtaining Ru-doped NH2-MIL-125(Ti) metal organic framework through a hydrothermal strategy. Further adding ruthenium salt to make Ti in the Ru-doped NH2-MIL-125(Ti) metal organic framework 4+ With Ru 3+ Metal cation exchange, by controlling the temperature and time of carbonization, Ru single atoms and reduced Ru metal clusters can be better embedded in the TiO2 lattice to form a rich heterojunction interface. In addition, there are a large number of Ru-Ti bonds at the heterojunction interface, which increases the number of active sites, ensures the effective transfer of electrons from Ti to Ru, and gives the Ru active sites a low metallic valence state.