The invention provides a sustained-release microcapsule-coated composite vitamin pre-mixed feed which has good stability and has sustained-release and bacterial inhibiting and sterilizing effects. 1 kg of the pre-mixed feed includes the following components, 20-100 g of microcapsule-coated composite vitamin, 20-50 g of amino acid chelated iron, 5-18 g of amino acid chelated copper, 20-45 g of amino acid chelated zinc, 4-5 g of manganese sulfate monohydrate, 0.10-0.11 g of 1% potassium iodate, 0.59-0.68 g of cobalt chloride, 0.05-0.14 g of 1% sodium selenite, 20-30 g of arginine, 5.9-6.4 g of threonine, 1.8-6.5 g of an enzyme preparation, 18-70 g of an acidification agent, 1.1-3.0 g of an anti-oxidizing agent, 8-50 g of a flavoring agent, 7.5-9.0 g of medicine additives, 78-95 g of 50% choline chloride and the balanced being a carrier which includes nano chelated attapulgite, and at least one of corn protein powder, stone powder, zeolite powder, medical stone or montmorillonite.