126 results about "Phthalic acid anhydride" patented technology

The invention discloses unsaturated polyester resin for imitation jade handicrafts and a preparation method thereof, and belongs to the technical field of polyester resin. Comprising the following components: diethylene glycol, methylpropanediol, propylene glycol, maleic anhydride, phthalic anhydride, an antioxidant, a polymerization inhibitor, paraffin, a stabilizer, an ultraviolet light absorber, a whitening agent and a diluent. The weight ratio of the propylene glycol to the methyl propylene glycol is (1.0-1.3): 1, and the methyl propylene glycol accounts for 20-22% of the total amount of the dihydric alcohol; the weight ratio of maleic anhydride to phthalic anhydride is (0.46-0.52): 1; the preparation method comprises 1) adding the raw materials and the antioxidant into a reactor, carrying out heating, carrying out heat preservation for 0.5-1.0 h and continuing heating, 2) carrying out a reaction for 2-3 h after heating, carrying out dehydration until an acid value is 20-25 mgKOH / g, and 3) carrying out cooling, adding the auxiliary agent and carrying out uniform mixing so that the unsaturated polyester resin is obtained.

The present invention discloses a method for measuring the hydroxyl value of a polyether polyol using nuclear magnetic resonance phosphorus spectroscopy, comprising: 1) adding a polyether polyol sample to be tested and an internal standard bisphenol A to a deuterated reagent and dissolving them by ultrasonication; 2) adding a phosphorus oxychloride compound and an acid binding agent to the mixture and allowing them to react fully to obtain corresponding different derivatized phosphorus-containing products; 3) performing a phosphorus spectroscopy test in a nuclear magnetic resonance analyzer to obtain nuclear magnetic resonance phosphorus spectroscopy data, processing and analyzing the data, integrating the nuclear magnetic resonance characteristic peak areas of the phosphorus-containing products after derivatization of the polyether polyol sample and the internal standard bisphenol A, and normalizing them to 100%, and calculating the hydroxyl value of the sample to be tested based on the molar ratio relationship between the products. The hydroxyl value result obtained by the present method has a relative deviation of less than 5% from the result obtained by the phthalic anhydride acylation method in the national standard GB / T 12008.3-2009, and the two results are close and highly accurate. The analytical testing method of the present invention is simple, has low pollution, and is short in time.

The invention relates to the technical field of paint removers, and particularly discloses an environment-friendly water-based paint remover for tools as well as a preparation method and application of the environment-friendly water-based paint remover. The invention provides an environment-friendly water-based paint remover for tools. The environment-friendly water-based paint remover is specifically prepared from 280-320 parts of a main solvent, 40-54 parts of a solubilizer, 30-40 parts of a surfactant, 7-13 parts of a penetrating agent, 130-150 parts of monoethanolamine, 8-12 parts of sulfonic acid, 40-58 parts of caustic soda flakes, 1-5 parts of a thickening agent and 280-320 parts of water. The main solvent is formed by mixing benzyl alcohol and dipropylene glycol monomethyl ether according to the weight ratio of (0.1-1): (1-10); the preparation method of the penetrant comprises the following steps: reacting phthalic anhydride, ethylene glycol and hydroquinone to obtain modified polyester; and then mixing the modified polyester with isooctanol polyoxyethylene ether JFC-3 to obtain the modified polyester. The paint remover prepared by the invention has good paint removal efficiency, and can effectively improve the production efficiency of an automobile coating factory and reduce the comprehensive cost.

The invention provides a method for detecting the hydroxyl value of a polyether material. The method comprises the following steps: (1) constructing a standard quantitative system of a derivatization reagent; (2) fully reacting a to-be-detected polyether material with the excessive derivatization reagent; (3) testing the peak area of the unreacted derivatization reagent by adopting chromatography; (4) comparing with a standard quantitative system of the derivatization reagent, and calculating the content of the unreacted derivatization reagent; and (5) calculating the consumption of the derivatization reagent in the step (2) by using the calculated content of the unreacted derivatization reagent, thereby calculating the hydroxyl value of the polyether material according to the stoichiometric relationship. Wherein the derivatization reagent comprises at least one hydroxyl esterifying agent selected from the following groups: phthalic anhydride, acetic anhydride and benzoyl chloride.

The invention relates to a method for reducing the content of 2, 6-diaminotoluene and / or 2, 4-diaminotoluene in a polyol, in particular in a recovered polyol, in which a polyol containing 2, 6-diaminotoluene and / or 2, 4-diaminotoluene is reacted with at least one compound selected from the group consisting of a), b) and c), in which the polyol containing 2, 6-diaminotoluene and / or 2, 4-diaminotoluene is reacted with at least one compound selected from the group consisting of a), b) and c), wherein: a) one or more epoxy-functional compounds, preferably dodecyl / tetradecyl glycidyl ethers, b) one or more anhydrides, in particular phthalic anhydrides, and c) one or more aldehydes, preferably benzaldehyde.

The invention discloses a 4-BrPA / beta-CD supramolecular photosensitizer as well as a preparation method and application thereof, and belongs to the field of biomedical materials. According to the method, beta-cyclodextrin is used as a subject, 4-bromophthalic anhydride is used as an object, and the water-soluble photosensitizer is constructed through a chemically modified supramolecular assembly strategy. The preparation method comprises the following specific steps: reacting beta-cyclodextrin with paratoluensulfonyl chloride to obtain mono-(6-O-paratoluensulfonyl)-beta-cyclodextrin; then carrying out a reaction with ethidene diamine to obtain mono-(6-ethidene diamine-6-deoxy)-beta-cyclodextrin; then reacting with 4-bromophthalic anhydride in N, N-dimethylformamide, and precipitating and purifying through ethyl acetate to obtain a crude product; and finally, carrying out ultrasonic treatment, centrifugal separation and freeze drying to obtain a pure product. The prepared 4-BrPA / beta-CD supramolecular photosensitizer is excellent in water solubility, has at least 7 excitation centers in a visible light region of 400-520 nm, correspondingly generates at least 7 emission centers in a range of 500-780 nm, has a maximum excitation wavelength of about 460 + / -10 nm and a maximum emission wavelength of about 620 + / -10 nm, has an extremely wide visible light response characteristic, and can be used for antibacterial photodynamic therapy.

The application discloses an indoor moisture-proof and water-resistant gypsum board and a preparation method thereof, and belongs to the technical field of gypsum board preparation. The preparation method of the indoor moisture-proof and water-resistant gypsum board comprises the following steps: S1, uniformly mixing building gypsum, modified fluorite gypsum, deionized water, a polyester adhesive, a composite water reducing agent, blast furnace slag powder and the like to obtain a gypsum slurry; S2, paving the gypsum slurry on a first layer of cover paper, paving a second layer of cover paper on the gypsum slurry, and performing compaction, final setting, drying and solidification to obtain the indoor moisture-proof and water-resistant gypsum board. The composite water reducing agent is obtained by the reaction of ethyl vinyl ether, trichlorofluoroethylene and allyltrimethoxysilane. The polyester adhesive is obtained by the reaction of allyl alcohol, phthalic anhydride and triallyl cyanurate. The prepared gypsum board not only has good moisture-proof and water-resistant performance, but also has good mechanical properties, thereby prolonging the service life and ensuring the quality of the gypsum board to a certain extent.

Provided is a polyimide including: a dianhydride monomer including at least one selected from the group consisting of 3, 3 ', 4, 4'-benzophenone tetracarboxylic acid dianhydride (BTDA), oxybis-phthalic anhydride (ODPA), 4, 4 '-(hexafluoroisopropylidene) diphthalic anhydride (6FDA), and 3, 3', 4, 4 '-diphenylsulfone tetracarboxylic acid dianhydride as polymerization units, and a diamine monomer including at least one selected from the group consisting of 3, 3', 4, 4 '-benzophenone tetracarboxylic acid dianhydride (BTDA), oxybis-phthalic anhydride (ODPA), 4, 4'-(hexafluoroisopropylidene) diphthalic anhydride (6FDA), and 3, 3 ', 4, 4'-diphenylsulfone tetracarboxylic acid dianhydride as polymerization units; the diamine monomer comprises 4, 4 '-methylenebis (2, 6-diethylaniline) (MEDA).

The invention relates to the technical field of chemical preparation, and discloses a preparation method of a phthalimide compound, which comprises the following steps: S1, raw material mixing: sequentially adding phthalic anhydride, a primary amine compound, p-toluenesulfonic acid and phosphorus pentoxide into a reaction container with a stirring device and a temperature control module, and stirring for 1-2 hours; adding ethanol as a solvent, and carrying out a stirring reaction; s2, curing: cooling the reaction liquid to 20-25 DEG C, slowly adding deionized water into the reaction liquid while stirring, standing, and separating out a solid product; a traditional dehydrating agent is changed into a low-cost green dehydrating agent combination, so that the cost loss is reduced, the stimulation effect is reduced, the catalytic activity is equivalent to that of p-toluenesulfonic acid by adding a new sulfonic group functional polymer, but the problems of volatility of liquid acid and equipment corrosion are avoided, a low-toxicity and low-cost solvent of ethanol is added, the toxicity is reduced, and the environment-friendly dehydrating agent is prepared. The preparation is safer, the cost is lower, and the applicability is wider.

The invention discloses corrosion-resistant waterproof aluminum foil glass fabric and a preparation method thereof, and belongs to the technical field of aluminum foil composite glass fabric. The corrosion-resistant waterproof aluminum foil glass fabric sequentially comprises a waterproof glass fabric, a high-temperature-resistant adhesive layer and an aluminum foil from bottom to top, the waterproof glass fabric is obtained by padding a waterproof finishing agent; the waterproof finishing agent is mainly prepared from the following raw material components: a silane coupling agent, hydroxyl-terminated fluorine-containing dihydric alcohol, isophorone diisocyanate and polycaprolactone; the high-temperature-resistant adhesive is mainly prepared from the following raw material components: 4, 4 '-oxydiphthalic anhydride, 4, 4-(hexafluoroisopropyl) bis (p-phenoxy) diphenylamine, 3, 3'-diaminodiphenyl sulfone, 1, 3-bis (3-aminopropyl)-1, 1, 3, 3-tetramethyldisiloxane, 4-amino-2-hydroxybenzaldehyde and o-phenylenediamine, and the high-temperature-resistant adhesive is prepared from the following raw material components: 4, 4 '-oxydiphthalic anhydride, 4, 4-(hexafluoroisopropyl) bis (p-phenoxy) diphenylamine, 4, 4-(hexafluoroisopropyl) bis (p-phenoxy) diphenylamine, 3, 3'-diaminodiphenyl sulfone, 1, 3-bis (3-aminopropyl) The corrosion-resistant waterproof aluminum foil glass fiber cloth prepared by the invention is relatively good in high temperature resistance, corrosion resistance and waterproofness.

This invention relates to a taraxasterol nitrobenzoate derivative in the field of medicinal chemistry, with the following structural formula: Compound B is obtained by reacting taraxasterol 1 with 4-nitrophthalic anhydride in a suitable alkaline catalyst and organic solvent. This synthetic route offers high yield and is easy to implement. Activity tests demonstrate that the taraxasterol nitrobenzoate derivative shown as B, designed and synthesized in this invention, is a suitable antitumor drug candidate, particularly as a candidate drug for lung cancer.

This invention discloses a method for preparing a supported low-carbon hydrocarbon deodorization catalyst. The method includes: (1) preparing a catalyst containing M... 2+ and M' 3+ (1) Add molecular sieve to the solution and stir evenly; (2) React the obtained suspension with a mixed solution of NaOH and Na2CO3 or a weak alkaline solution under stirring; (3) Obtain the composite carrier by drying and calcination; (4) Prepare a cobalt salt solution and transfer Co to the cobalt salt solution by ion exchange. 2+ (5) After filtration and drying, Co molecular sieve solid alkali is obtained; (6) Co molecular sieve solid alkali, ammonium phthalate sulfonate, urea, ammonium molybdate, and phthalic anhydride are added in proportion and ground evenly; (7) The obtained material is heated under an inert atmosphere to react and obtain the catalyst product. In the catalyst prepared by this invention, sulfonated cobalt phthalocyanine is combined with molecular sieve through chemical bonds, the active component has a stronger binding force and a longer service life.

The invention provides a retarder, retarded acid and a preparation method and application thereof, and relates to the technical field of acidification transformation of carbonate reservoirs in oil and gas field development, the retarder comprises the following components in percentage by mass: 50%-70% of a main polymer, 15%-25% of a film-forming acceleration component, 10%-15% of an acid-resistant stable component and 5%-10% of a dispersing aid; the main body polymer is a quadripolymer and is formed by copolymerizing a cationic monomer, a bidentate anchoring monomer, a supramolecular self-assembly monomer and an acid-resistant monomer, the cationic monomer is methacryloyloxyethyl trimethyl ammonium chloride or acryloyloxyethyl trimethyl ammonium chloride, the bidentate anchoring monomer is phthalic anhydride modified acrylate, and the supramolecular self-assembly monomer is a supramolecular self-assembly monomer. The supramolecular self-assembly monomer is carbamido ethyl methacrylate, and the acid-resistant monomer is 2-acrylamide-2-methylpropanesulfonic acid; the retarder is obviously superior to the conventional retarded acid in the aspects of stability, film-forming speed, retarding effect, effective acting distance and reservoir protection.

The invention belongs to the technical field of constructional engineering, and particularly discloses recycled concrete with a self-repairing function and a preparation method of the recycled concrete. The concrete comprises a base material, a function regulator and a microbial self-repairing agent, the base material comprises cement and recycled aggregate from construction waste, the function regulator comprises a water reducing agent, a mineral admixture and a composite fiber material, and the microbial self-repairing agent is microbial self-repairing slurry. The composite fiber material comprises esterified modified cellulose and polypropylene fiber, and a modifier of the esterified modified cellulose comprises S-acetyl mercaptosuccinic anhydride and 4-phenoxy phthalic anhydride. The internal structure of the concrete is optimized through the composite fiber material, and in cooperation with the in-situ deposition effect of microbial mineralization products, the compactness and defect self-repairing capacity of a matrix are remarkably improved. According to the technology, efficient resource utilization of the construction waste is achieved, and an environment-friendly material solution is provided for green construction engineering.

The invention relates to the technical field of chemical raw material preparation, in particular to a continuous phthalic dicarboxaldehyde preparation reaction device and process. The stirring device comprises a stirring paddle rotationally connected to the axis of the reaction kettle, the top of the reaction kettle is communicated with a feed port, and the bottom of the reaction kettle is communicated with a discharge port; the upper part of the reaction kettle is provided with a pair of stirring paddles, and the stirring paddles are positioned above the liquid level of a reactant and are symmetrically arranged; after heat is generated by reaction, air above reaction liquid expands and rises to penetrate through the heat dissipation holes to reach the position above the protective cover to be in contact with flowing cold air conveyed by the fan for heat exchange, water vapor in the hot air is liquefied into condensed water when meeting cold, and the condensed water flows along the upper surface of the protective cover and is condensed by the fan. And the continuously rising hot air in the heat dissipation holes prevents the condensed water from penetrating through the heat dissipation holes and dripping into the reaction liquid below, so that phthalic anhydride is hydrolyzed into phthalic acid, and the normal proceeding of the subsequent reaction is influenced.

There is provided a method for efficiently produce hydroxypropyl methyl cellulose phthalate (HPMCP) having excellent flowability, where acetic acid in a reaction product mixture subjected to a wash and recovery step can be reduced. More specifically, there is provided a method for producing HPMCP including an esterification step of esterifying hydroxypropyl methyl cellulose (HPMC) with phthalic anhydride in acetic acid as a solvent to obtain a reaction product solution containing HPMCP; a water addition step of adding water to the reaction product solution to obtain a water-added reaction product solution; an acetic acid removal step of removing at least a portion of the acetic acid from the water-added reaction product solution to obtain a mixture having an acetic acid content reduced; and a wash and recovery step of washing the mixture and recovering the HPMCP.

The invention relates to the technical field of alkyd resin-based rusty anti-rust coatings, and particularly discloses a rusty anti-rust coating and a preparation method thereof. The on-rust anti-rust coating comprises the following raw materials: composite modified resin, an emulsifier, a filler, an anti-rust pigment and a rust conversion agent, the composite modified resin is prepared by modifying alkyd resin, coumarone resin and polyether polyurethane resin through maleic anhydride; the alkyd resin comprises the following raw materials: polyol, phthalic anhydride, terephthalic acid, soybean oil fatty acid and a high-flash-point aromatic solvent. A composite system of alkyd resin, coumarone resin and polyether polyurethane resin realizes comprehensive improvement of adhesive force, corrosion resistance, constructability and environmental adaptability through advantage complementation, and is matched with an emulsifier, a filler, an anti-rust pigment and a rust conversion agent, so that the adhesive force to a rusty substrate and the corrosion resistance of the coating are remarkably improved, and the service life of the coating is prolonged. And the method has remarkable technical economy and market application potential.

The invention discloses tough synergistic composite modified asphalt for a hydraulic panel leveling layer and a preparation method of the tough synergistic composite modified asphalt, and the raw materials of the composite modified asphalt comprise matrix asphalt, a composite modifier, rubber oil and a vulcanizing agent, the composite modifier is prepared from the following raw materials: epoxidized castor oil, HDI (hexamethylene diisocyanate), a polymerization inhibitor, phthalic anhydride, an inhibitor and a chain terminator. HDI is dropwise added into epoxidized castor oil added with a polymerization inhibitor to generate epoxidized polyurethane, the epoxidized polyurethane, phthalic anhydride and an inhibitor form composite colloidal particles with a certain size through a granulator, and a long chain of the epoxidized castor oil and an HDI cross-linked network can effectively help the modified asphalt to realize toughness synergy; and the viscosity of the modified asphalt can be effectively reduced by controlling the cross-linking density, so that the material is more suitable for preparing the asphalt concrete which is tough, synergistic and long in service life and is used for a leveling cementing layer of a hydraulic asphalt concrete panel.

The invention relates to the technical field of preparation of chemical raw materials, in particular to a preparation process of tetrachlorophthalic anhydride, which comprises the following steps: S1, adding phthalic anhydride, chlorine, chlorosulfonic acid and a modified iodine catalyst into a reaction kettle for chlorination reaction to obtain a reacted material; and S2, transferring the reacted material into a crystallization kettle, carrying out cooling crystallization, introducing compressed air to recover chlorosulfonic acid, and carrying out temperature-controlled washing, centrifugal dewatering and drying to obtain a tetrachlorophthalic anhydride product. According to the preparation process, the iodine loss rate can be remarkably reduced, the catalytic efficiency and the reaction selectivity are improved, and finally high-purity and high-yield tetrachlorophthalic anhydride is prepared.

The utility model relates to the technical field of chemical waste recovery, in particular to a phthalic anhydride waste recovery device which comprises a box body and supporting rods, the right side of the lower end of the box body is fixedly connected with the two supporting rods, and the lower ends of the supporting rods on the two sides are movably connected with arc blocks through pin shafts. The lower ends of the arc blocks on the two sides are fixedly connected with a bottom plate, and a pushing device is arranged at the upper end of the bottom plate. According to the phthalic anhydride waste material recovery device, through cooperation of the pushing device and the separation and recovery device, the box body can incline towards one side of the liquid discharge pipe, an operator opens a valve to discharge waste liquid in the box body and opens and collects the discharged waste liquid, a square plate is pulled to drive a frame body to be pulled out, and then the box body is separated and recovered. Solid waste on the surface of the screen plate is collected, the solid waste and liquid waste are independently treated in a targeted mode, solid-liquid separation and temporary storage of the waste can be carried out, and the device is more convenient to use.

The invention discloses an indoor moisture-proof and water-resistant gypsum board and a preparation method thereof, and belongs to the technical field of gypsum board preparation. The preparation method of the indoor moisture-proof and water-resistant gypsum board comprises the following steps: S1, uniformly mixing building gypsum, modified fluorgypsum, deionized water, a polyester adhesive, a composite water reducing agent, blast furnace slag powder and the like to obtain gypsum slurry; s2, the gypsum slurry is flatly laid on the first layer of surface protection paper, the second layer of surface protection paper is flatly laid on the gypsum slurry, compaction, final setting and drying curing are conducted, and the indoor damp-proof and water-resistant gypsum board is prepared; wherein the composite water reducing agent is obtained by carrying out a reaction on ethyl vinyl ether, trichlorofluoroethylene and allyl trimethoxy silane; the polyester adhesive is obtained by reaction of allyl alcohol, phthalic anhydride and triallyl cyanurate; the prepared gypsum board not only has good moisture-proof and water-resistant performance, but also has good mechanical performance, the service life of the gypsum board is prolonged to a certain extent, and meanwhile the quality of the gypsum board is guaranteed.

The invention relates to the technical field of composite materials, in particular to a low-temperature medium leakage prevention carbon fiber composite material with self-repairing and self-adaptive sealing functions and a preparation method and application thereof. The preparation method of the composite material comprises the following steps: S1, adding 4, 4 '-diaminodiphenyl ether and 3, 5-diaminobenzoic acid-3-trifluoromethyl phenyl ester into dimethylacetamide, stirring, then adding 4, 4'-hexafluoroisopropyl phthalic anhydride, stirring, heating to room temperature, and continuously stirring to obtain fluorine-containing side chain polyimide; adding an MXene dispersion liquid into the fluorine-containing side chain polyimide to obtain a polyimide adhesive film layer, S2, preparing a carbon fiber bearing layer; s3, adding an aromatic disulfide bond repairing agent into water, then adding isophorone diisocyanate and polyether amine for reaction, and then mixing with polyethylene glycol terephthalate to prepare a self-repairing impermeable layer; s4, preparing a double-layer gradient film; and S5, preparing the carbon fiber composite material.

The application discloses a novel dimer-induced AIE smart material and application thereof, and a preparation method thereof, which comprises the following steps: mixing 4-methyl phthalic anhydride, 2-hydrazinyl benzothiazole and glacial acetic acid to react, and obtaining the novel dimer-induced AIE smart material. The novel dimer-induced AIE smart material is used as a probe to detect triethylamine and dichloromethane. The novel dimer-induced AIE smart material is used as an emission probe to quantitatively detect Zn 2+ . The novel dimer-induced AIE smart material can be used for on-site evaluation of freshness of beef and shrimps, and can be used for detection of Zn 2+ in a biological system.

The invention relates to the technical field of paper ink, and discloses polyester-based decorative paper ink and a preparation method thereof.The preparation method comprises the following steps that S1, ramie fibers are pretreated; s3, in a nitrogen atmosphere, adding itaconic acid, phthalic anhydride and 1, 6-hexanediol into a reactor, stirring and mixing, continuously adding p-toluenesulfonic acid and hydroquinone, ending the reaction until no water is generated, then adding dibutyltin dilaurate, and carrying out reduced pressure reaction to obtain unsaturated polyester; s4, adding unsaturated polyester, the modified ramie fiber and hydrogen-containing silicone oil into a reactor, stirring and mixing, adding a platinum catalyst, and reacting to obtain a polyester-based intermediate; and S5, adding water-based acrylic resin, the polyester-based intermediate, a flatting agent and a dispersing agent into the reactor, and stirring to obtain the polyester-based decorative paper ink. The polyester-based decorative paper ink provided by the invention has good adhesive force, water resistance and wear resistance.

The application discloses a preparation method of high-purity fluorescein sodium. The fluorescein is synthesized from o-phthalic anhydride and resorcinol under the catalysis of sodium bisulfate or potassium bisulfate without using an organic solvent as a solvent, and then the fluorescein is used to prepare fluorescein diacetate; and the high-purity fluorescein sodium is obtained through a synthesis route of saponification, acidification and salt formation. The synthesis route has mild reaction conditions, simple operation steps, no organic solvent, avoids the generation of organic solvent pollution, has low raw material and auxiliary material consumption, low production cost, high purity of reactants and high yield.

The application relates to a new energy graphite heat pipe and a preparation method thereof. The method comprises the following steps: 1) mixing, oscillating and stirring nanographene, N-methyl-2-pyrrolidone and polyether modified polysiloxane to obtain a mixed solution A; 2) weighing 4,4'-oxybisphthalic anhydride and 4,4'-oxydianiline, adding the two into the mixed solution A, heating, stirring for 3-5 hours to obtain a mixture B; 3) weighing N-hydroxyethyl acrylamide, polytrimethylene ether glycol and methylene succinic acid, adding the three into the mixture A, stirring, drying and grinding to obtain modified nanographene; 4) mixing, oscillating and stirring the modified nanographene, water and a settlement preventing agent to obtain a modified nanographene fluid; 5) adopting copper material to make a heat pipe, filling the modified nanographene fluid into the heat pipe, intercommunicating two ends of the heat pipe and forming a closed loop circuit to obtain a graphite heat pipe; the fluid in the graphite heat pipe is not prone to settlement, and the heat conduction performance and practicability are improved.

The invention relates to a two-step method for preparing 1, 2, 3, 4-butanetetracarboxylic acid tetraalkyl ester. The subject of the invention is a two-step process for the preparation of 1, 2, 3, 4-butanetetracarboxylic acid tetraalkyl esters containing alkyl groups having 1 to 6 carbon atoms starting from tetrahydrophthalic anhydride (THPA). The invention relates to a process for the preparation of 1, 2, 3, 4-butanetetracarboxylic acid, comprising the oxidation of tetrahydrophthalic anhydride (THPA) followed by the esterification of the resulting 1, 2, 3, 4-butanetetracarboxylic acid with an alcohol having 1 to 6 carbon atoms.

A set of serum metabolic biomarkers and detection kit for detecting drug-resistant tuberculosis are provided. The set of the serum metabolic biomarkers includes 17 serum metabolic biomarkers. The 17 serum metabolic biomarkers are verified to be associated with tuberculosis based on the level changes of these biomarkers. The 17 metabolites includes taurine, homocysteine, uric acid, ascorbic acid, suberylglycine, uridine, dopamine 4-sulfate, inosinic acid, glyceraldehyde phosphate, [3-methoxy-4-(phosphoryl)phenyl]carbonyl sulfonic acid, nuclomedone, n4-cyclopropyl-6-(2,3-dichlorophenyl)-1,2,3,4-tetrahydropyrimidine-2,4-diimine, 1-[2-chlorine-2-(2,4-dichlorophenyl)ethenyl]-1,2,4-triazole, tetrachloro-phthalic anhydride, malotilate, fulvic acid, and L-neopterin. The serum metabolic biomarkers and detection kit for detecting drug-resistant tuberculosis can assist doctors in accurately diagnosing the disease, which is of great significance for the diagnosis and mass screening for drug-resistant tuberculosis.

The application discloses a phthalocyanine cobalt / pyridine nitrogen skeleton substituted phthalocyanine copper / asphalt coke active carbon composite catalytic material and a preparation method and application thereof, and the method comprises the following steps: 1, pyridine-2,3-dicarboxylic acid, urea, ammonium molybdate, copper chloride dihydrate and asphalt coke active carbon are mixed to obtain a mixture A; 2, the mixture A is kept at 100-180 DEG C, and then kept at 200-350 DEG C to obtain a product B; 3, the product B is ground, soaked, washed and dried in sequence to obtain pyridine nitrogen skeleton substituted phthalocyanine copper / asphalt coke active carbon; 4, phthalic anhydride, urea, ammonium molybdate, cobalt chloride hexahydrate and pyridine nitrogen skeleton substituted phthalocyanine copper / asphalt coke active carbon are mixed to obtain a mixture C; 5, the mixture C is kept at 100-180 DEG C, and then kept at 200-350 DEG C to obtain a product D; 6, the product D is ground, soaked, washed and dried in sequence to obtain the phthalocyanine cobalt / pyridine nitrogen skeleton substituted phthalocyanine copper / asphalt coke active carbon composite catalytic material, the purity of the material is high, and the discharge time and voltage of a Li / SOCl2 battery are improved.

The invention relates to the technical field of ceramic glazes, and discloses an anti-glaze-crack antibacterial ceramic glaze and a preparation method thereof.The preparation method comprises the steps that polyethyleneimine and 4-hydroxyphthalic anhydride react to obtain modified polyethyleneimine, then nano titanium dioxide serves as a photocatalytic antibacterial agent and is subjected to ball milling and blending with feldspar, silica powder, calcite and the like, and the anti-glaze-crack antibacterial ceramic glaze is obtained. Glazing and sintering at high temperature to obtain the anti-glaze-crack antibacterial ceramic glaze. A large number of hydroxyl groups, carboxyl groups and o-hydroxybenzoic acid structures are introduced into the modified polyethyleneimine, so that the surface modification and dispersion effects on the nano titanium dioxide are realized, the dispersity of the nano titanium dioxide in the ceramic glaze is improved, more photocatalytic active sites are exposed, and a higher sterilization rate is shown; the modified polyethyleneimine serves as a dispersing agent of the glaze, agglomeration of inorganic particles such as silica powder in the glaze is reduced, the uniformity of the glaze is improved, the quality of a fired glaze surface is improved, and better glaze crack resistance is shown.