12 results about "N-pentanol" patented technology

The present application relates to the field of magnesium-aluminum composite oxide preparation, and discloses a magnesium-aluminum composite oxide and a preparation method thereof.The method comprises the following steps: (1) under anhydrous conditions, performing a first reaction on aluminum and a first aliphatic alcohol to obtain an alkoxide aluminum-containing material; (2) under the action of a catalyst, performing a second reaction on the alkoxide aluminum-containing material obtained in step (1), magnesium and a second aliphatic alcohol under anhydrous conditions; (3) performing hydrolysis on the reaction product of step (2) to obtain a magnesium-aluminum bimetallic alkoxide, and then performing optional drying and calcination to obtain a magnesium-aluminum composite oxide; wherein the first aliphatic alcohol and the second aliphatic alcohol each independently comprise n-pentanol and optionally n-hexanol. The preparation method of the magnesium-aluminum composite oxide provided by the present application can obtain a high-purity magnesium-aluminum composite oxide without subsequent purification treatment, and has the advantages of short initiation time and short reaction time.

The invention relates to the technical field of cholesterol preparation, and discloses a preparation method of plant-derived cholesterol, which comprises the following steps: 1) heating and dissolving phytosterol with n-amyl alcohol, adding stigmasterol until saturation, cooling and crystallizing, and then carrying out solid-liquid separation to obtain a stigmasterol crude product; 2) heating and dissolving the stigmasterol crude product with absolute ethyl alcohol, adding pyridine, and continuously dropwise adding acetic anhydride for reaction; after the reaction is completed, adding deionized water for mixing, extracting with n-hexane for multiple times, separating an upper-layer oil phase, and concentrating and drying the oil phase to obtain a white solid; 3, the white solid is subjected to oxidation reduction, witting reaction and hydrogenation reaction, and cholesterol is obtained.The method has the advantages that compared with the prior art that the plant source cholesterol is directly prepared from the raw material phytosterol, the process is simplified, and meanwhile the product yield can be increased.

The invention belongs to the technical field of medicine synthesis processes, and particularly relates to a preparation method of high-yield and high-purity tandospirone citrate. According to the method, pyrimido piperazine quaternary ammonium salt and isoindoledione are used as raw materials, a toluene and n-butanol and / or n-amyl alcohol mixed solvent is used as a solvent, tandospirone can be generated under the alkaline condition without adding a phase transfer catalyst, after acid adjustment extraction and specific organic solvent reverse phase impurity removal, a water phase is adjusted to be alkaline, and the tandospirone is obtained. And extracting with toluene, and adding a citric acid ethanol solution to directly separate out a citric acid tandospirone solid. The preparation process disclosed by the invention has a very good impurity removal effect, and the obtained tandospirone citrate is high in purity, high in process yield, good in atom economy and low in output of three wastes.

The invention relates to the technical field of fine chemical engineering, in particular to a method for preparing cyclopentanol based on one-step synthesis of cyclopentene, which comprises the following steps: step 1) preparation of a modified strongly acidic cation exchange resin catalyst; (2) synthesizing by a one-step method; step 3) separation; and 4) purifying. In the step (2), under the inert atmosphere, the modified strong-acid cation exchange resin catalyst, cyclopentene, n-amyl alcohol and water are mixed and react; wherein the molar ratio of the cyclopentene to the water is (3-5): 1, the addition amount of the n-amyl alcohol is 1.0-2.0 times of the mass of the cyclopentene, and the n-amyl alcohol and the water form a cosolvent system. The method has the advantages that the process route is clean, efficient and pollution-free, the conversion per pass is high, the product is easy to separate, the low-temperature physical property of the product is good, the solvent and reactants in the whole reaction process can be repeatedly used, efficient and environment-friendly hydration preparation of cyclopentanol from cyclopentene can be realized, and the method has a good industrial application prospect.

The invention discloses an interpenetrating type iron-based metal organic framework material and a preparation method and application thereof, the molecular formula of the material is [Fe3O4 (H2O) 3 (L1) (L2) 4 / 3], in the formula, L1 represents deprotonated 4-(4-carboxybenzamido) benzoic acid, L2 represents deprotonated 1, 3, 5-tri (4-carboxyphenyl) benzene, and n represents 1, 3, 5-tri (4-carboxyphenyl) benzene; the material belongs to a hexagonal crystal system and an R-3c space group, and is prepared by taking a trinuclear iron cluster, 4-(4-carboxybenzamido) benzoic acid and 1, 3, 5-tri (4-carboxyphenyl) benzene as raw materials, acetic acid as a template agent and N, N-dimethylformamide and n-amyl alcohol as solvents through solvothermal reaction. The interpenetrating type iron-based metal organic framework material disclosed by the invention has a relatively large specific surface area and a relatively large pore structure, has good adsorption performance on methane and carbon dioxide, and has a wide application prospect in the fields of methane storage and flue gas carbon dioxide capture.

The invention provides an extraction method of an asiaticoside compound, and relates to the technical field of medicine extraction. The method comprises the following steps: mixing a crude centella asiatica product with a first solvent (ethanol or methanol) for extraction, concentrating an extracting solution to be dry, dissolving an obtained first concentrate with a second solvent (n-amyl alcohol or isoamyl alcohol saturated aqueous solution), mixing with a third solvent (water saturated n-amyl alcohol or isoamyl alcohol) for extraction, collecting an organic layer, and concentrating to be dry, so as to obtain the centella asiatica extract. And dissolving the obtained second concentrate with a fourth solvent (methanol or ethanol), mixing the dissolved second concentrate with a fifth solvent (dichloromethane or acetonitrile), and carrying out precipitation to obtain a precipitate which is an asiaticoside compound product. Compared with a column chromatography method, the method for extracting the asiaticoside compound by adopting a solvent method has the advantages of simplicity in operation, large sample treatment capacity, easiness in solvent recovery and application and the like, is suitable for industrial production, and can be used for extracting the asiaticoside compound with high content (not less than 70wt%) from a crude product of centella asiatica.

The invention discloses a low-temperature paraffin remover for paraffin with high carbon number, which belongs to the field of paraffin removers and comprises the following components in parts by weight: 70-80 parts of a first solvent and a second solvent; 3-13 parts of a penetrating agent and 1-10 parts of a dispersing agent; 1-7 parts of an inhibitor; the first solvent is one of S1000, S1200, S1500, S1800, S2000, S2600, D40, D60, D80 and 1-ethyl-3-methylimidazolium tetrafluoroborate, and the second solvent is one of 1-ethyl-3-methylimidazolium tetrafluoroborate and 1-ethyl-3-methylimidazolium tetrafluoroborate; the second solvent is one or a mixture of more of petroleum ether 60 # to 90 #, petroleum ether 90 # to 120 #, petroleum ether 150 #, petroleum ether 200 #, n-heptane, dodecane, isododecane, nonane, 2-methyl-3-ethylpentane, 3-methylhexane, ethanol, acetone, dimethyl sulfoxide and tetrahydrofuran; and the penetrating agent is one of n-amyl alcohol, isoamyl alcohol, n-caprylic alcohol, hexanediol and ammonium adipate.

The application belongs to the technical field of medicine synthesis process, and particularly relates to a preparation method of high-yield and high-purity buspirone hydrochloride. The application takes 8-(2-pyrimidyl)-8-azido-5-5-azospiro[4.5]decane hydrobromide (referred to as pyrimidine piperazine quaternary ammonium salt) and 3,3-tetramethylene glutarimide as raw materials, takes a mixed solvent of toluene, normal pentanol and / or normal hexanol as a solvent, does not need to add a phase transfer catalyst, and can generate buspirone in the presence of sodium carbonate. After acid adjustment and extraction, toluene is removed in the reverse phase, the water phase is adjusted to be alkaline, toluene is extracted, hydrogen chloride ethanol solution is added, and buspirone hydrochloride solid is directly precipitated. The preparation process has a good removal effect on impurities, the obtained buspirone hydrochloride has high purity, high process yield, good atomic economy and small three-waste output.

A method for preparing an acrylate laminating adhesive by soap-free emulsion polymerization, and an acrylate laminating adhesive prepared by soap-free emulsion polymerization. In the method, an acrylate block oligomer with emulsifiability is synthesized by using a RAFT active radical polymerization process, and an acrylate monomer is emulsified by using the acrylate block oligomer for a semi-continuous emulsion polymerization, which overcomes a defect that traditional small molecule emulsifiers tend to migrate to a surface of an adhesive film to form a weak interface layer, resulting in a decreased bonding strength, a poor water resistance and the like. Further, in the disclosure, the use of n-pentanol as a chain transfer agent could not only reduce the molecular weight of polymer, improving fluidity and laminating uniformity of the adhesive, but also reduce the surface tension of the emulsion, improving coating wettability and levelling properties of the acrylate laminating adhesive.

The application provides a clay-solubilized heavy oil water-based viscosity-reducing and plug-removing agent and application thereof. The clay-solubilized heavy oil water-based viscosity-reducing and plug-removing agent comprises an organic dispersant, a first surfactant, an additive, a clay-solubilizing agent and water. The organic dispersant is tetrahydrofuran, the first surfactant is sodium dodecyl benzene sulfonate, the additive is n-pentanol, and the clay-solubilizing agent is a complex acid of hydrochloric acid and fluoroboric acid. The clay-solubilized heavy oil water-based viscosity-reducing and plug-removing agent can effectively solve the problems of sensitivity and oil sludge pollution and plug, the recovery degree of permeability is more than 66%, and the implementation of heavy oil chemical viscosity reduction mining is effectively promoted.

The invention discloses a method for preparing lignin oil by continuous hydrogenation depolymerization of lignin through microwave and microfluidics coupling, and belongs to the technical field of high-value utilization of biomass resources. The method comprises the following steps: adding water, mannitol, n-amyl alcohol and p-toluenesulfonic acid into a wood fiber raw material, performing in-situ extraction on lignin under microwaves, and performing capillary regulation to form a three-phase emulsion and a droplet microreactor; a Pd / carboxylated carbon nanotube-formic acid aqueous solution and n-amyl alcohol-lignin mixed flow form Pickering emulsion, microwave hydrogenation depolymerization is performed in a heart-shaped channel microreactor, a catalyst is cooled, separated and recycled, and an organic phase is distilled to obtain n-amyl alcohol and lignin oil. According to the invention, a series catalytic system for in-situ extraction of lignin and transfer hydrogenolysis is constructed, a micro-fluidic chip design is further combined, a complex one-pot reaction is divided into two characteristic reaction units, efficient preparation of high monophenol lignin oil is realized through continuous flow series connection, and the method is a novel simple, efficient and energy-saving lignin oil preparation strategy.

The application relates to the technical field of lithium-oxygen batteries, and discloses a preparation method of a fluffy-structure metal oxide composite material and a lithium-oxygen battery, which comprises the following steps: dissolving hexadecylpyridinium bromide and urea in water to obtain a first solution after stirring; mixing n-pentanol, ethyl silicate and cyclohexane to obtain a second solution after stirring; mixing the first solution and the second solution, carrying out hydrothermal reaction, cooling and vacuum filtering, drying the obtained filter cake, calcining, soaking the calcined product in sulfuric acid to obtain a preliminary composite product; mixing the preliminary composite product with anhydrous ethanol, adding metal salt and hexamethylenetetramine, carrying out secondary hydrothermal reaction, cooling and vacuum filtering, secondary drying the filter cake, secondary calcining, and finally alkali washing to obtain a final product. The composite material has a unique fluffy structure and good electrochemical performance.