44 results about "Calcium Phosphate Crystals" patented technology

The present invention provides inorganic-organic nanocomposite coatings for implant materials and methods for the production thereof. The coatings consist of a sequentially adsorbed polyelectrolyte film (SAPF) intergrown with calcium phosphate crystals. The substrate is selected from glass, polymer, metal or metal alloys. The SAPFs consist of successions of positively and negatively charged monolayers, comprising biocompatible polyelectrolytes, preferably polyaminoacids. The calcium phosphate crystals may comprise octacalcium phosphate, calcium deficient apatites, carbonate apatites, hydroxyapatite, or mixtures thereof, with particle sizes 50 nm to 2 μm. The inorganic phase is grown “in situ” within the polyelectrolyte organic matrix.

Methods and compositions are provided which contains preparations of calcium chelators, bisphosphonates, antibiotics, antimicrobial agents, cytostatic agents, calcium ATPase and pyrophosphatase pump inhibitors, calcium phosphate-crystal dissolving agents, agents effective against calcium phosphate-crystal nucleation and crystal growth, and / or a combination of supportive agents and which may be used for treating and or reducing pathological calcifications, the growth of Nanobacterium and calcification-induced diseases including, but not limited to, Arteriosclerosis, Atherosclerosis, Coronary Heart Disease, Chronic Heart Failure, Valve Calcifications, Arterial Aneurysms, Calcific Aortic Stenosis, Transient Cerebral Ischemia, Stroke, Peripheral Vascular Disease, Vascular Thrombosis, Dental Plaque, Gum Disease (dental pulp stones), Salivary Gland Stones, Chronic Infection Syndromes such as Chronic Fatigue Syndrome, Kidney and Bladder Stones, Gall Stones, Pancreas and Bowel Diseases (such as Pancreatic Duct Stones, Crohn's Disease, Colitis Ulcerosa), Liver Diseases (such as Liver Cirrhosis, Liver Cysts), Testicular Microliths, Chronic Calculous Prostatitis, Prostate Calcification, Calcification in Hemodialysis Patients, Malacoplakia, Autoimmune Diseases. Erythematosus, Scleroderma, Dermatomyositis, Antiphospholipid Syndrome, Arteritis Nodosa, Thrombocytopenia, Hemolytic Anemia, Myelitis, Livedo Reticularis, Chorea, Migraine, Juvenile Dermatomyositis, Grave's Disease, Hypothyreoidism, Type 1 Diabetes Mellitus, Addison's Disease, Hypopituitarism, Placental and Fetal Disorders, Polycystic Kidney Disease, Glomerulopathies, Eye Diseases (such as Corneal Calcifications, Cataracts, Macular Degeneration and Retinal Vasculature-derived Processes and other Retinal Degenerations, Retinal Nerve Degeneration, Retinitis, and Iritis), Ear Diseases (such as Otosclerosis, Degeneration of Otoliths and Symptoms from the Vestibular Organ and Inner Ear (Vertigo and Tinnitus)), Thyroglossal Cysts, Thyroid Cysts, Ovarian Cysts, Cancer (such as Meningiomas, Breast Cancer, Prostate Cancer, Thyroid Cancer, Serous Ovarian Adenocarcinoma), Skin Diseases (such as Calcinosis Cutis, Calciphylaxis, Psoriasis, Eczema, Lichen Ruber Planus), Rheumatoid Arthritis, Calcific Tenditis, Osteoarthritis, Fibromyalgia, Bone Spurs, Diffuse Interstitial Skeletal Hyperostosis, Intracranial Calcifications (such as Degenerative Disease Processes and Dementia), Erythrocyte-Related Diseases involving Anemia, Intraerythrocytic Nanobacterial Infection and Splenic Calcifications, Chronic Obstructive Pulmonary Disease, Broncholiths, Bronchial Stones, Neuropathy, Calcification and Encrustations of Implants, Mixed Calcified Biofilms, and Myelodegenerative Disorders (such as Multiple Sclerosis, Lou Gehrig's and Alzheimer's Disease) in humans and animals. The method comprises administering the various classes of compositions of the present invention, which together effectively inhibit or treat the development of calcifications in vivo.

The invention relates to a method for recovering sludge phosphorus from an urban sewage treatment plant, belonging to the technical fields of sludge treatment and resources. The method comprises the following steps: respectively carrying out gravity thickening on sludge releasing sludge phosphorus, sludge phosphorus releasing on sludge after the gravity thickening, solid-liquid separation on sludge after the sludge phosphorus releasing, sludge phosphorus recovery on supernatant fluid rich of phosphorus after the solid-liquid separation, and the like; the sludge phosphorus releasing on sludge after the gravity thickening is realized by treating the sludge by an acidification and normal-pressure microwave radiation combination method; and the sludge phosphorus recovery on supernatant fluid rich of phosphorus after the solid-liquid separation is realized by treating the supernatant fluid rich of phosphorus by a calcium phosphate crystallization process to obtain the deposit containing calcium phosphate crystal, then filtering the deposit containing calcium phosphate crystal and finally recovering the sludge phosphorus. The method not only can efficiently recover the phosphorus in the sludge from the urban sewage treatment plant, but also can achieve the aims of reducing the sludge and improving the depositing performance of the sludge.

The invention discloses a preparation method of a titanium dental implant, which includes the following steps: arranging the dental implant to be in spiral shape, increasing the initial contact area of the implant, improving the initial stability of the implant, increasing the surface area of the implant and improving the stress distribution at the bone interface; obtaining a rough surface through abrasive blasting; designing a porous structure on the surface of the implant through a laser etching method; preparing a porous TiO2 oxide film on the surface of the implant through an anodic oxidation method, wherein the oxide film has a rough surface and has round pits in different sizes at local parts; treating the anodized titanium surface through alkali liquor to form a titanium gel layer rich in Ti-OH groups which induce the production of calcium phosphate crystal nucleus to form an osteoid apatite layer. The invention processes the medical pure titanium to be in spiral shape and modifies the surface of the implant through a series of methods of abrasive blasting, laser etching and anodic oxidation so as to enhance the bonding strength of the implant and the bone and to improve the success rate of the repair of the implant.

The invention provides a bioactive glass ceramic fiber-PEEK resin composite artificial tooth and a preparation method. The preparation method of the artificial tooth comprises the four steps of preparing hydroxy calcium phosphate crystal glass ceramic fragments, preparing bioactive glass ceramic fibers, preparing the bioactive glass ceramic fiber-PEEK resin composite artificial tooth and conducting surface layer treatment on the portion, implanted into the alveolar bone, of the artificial tooth. The bioactive glass ceramic fiber-PEEK resin composite artificial tooth product prepared according to the method not only has the enough mechanical property, but also has the very good biocompatibility, and the mechanical property, the biocompatibility and the bone bonding strength are all greatly superior to those of a conventional artificial tooth product; in addition, the whole preparation technology process is simple, operation is convenient, and therefore the artificial tooth is very worthy of energetical popularization.

The invention discloses a process for preparing self- growing calcium phosphate crystal whisker tough porous biological ceramic material by using beta-calcium phosphate or hydroxyapatite powder, multiple phase addition agent, zirconium oxide and bonding agent as raw material through the steps of preparing multiple phase addition agent, making slip, modeling, blank pre-calcination and sintering process.

The invention relates to environmental protection and resource recycling techniques and devices and particularly relates to an induced crystallization reactor, a solid-liquid separation device and a method for efficiently recycling phosphorus from sewage. The induced crystallization reactor and the solid-liquid separation device comprise an water inlet part, a medicating part, an acidity regulating part, an aeration stirring part, an induced crystallization reaction part, a solid-liquid separation part and a crystal recycling part, wherein the induced crystallization reactor is communicated with the solid-liquid separation device to adequately play seed crystal induction function. According to the device and the method, calcite is utilized as a seed crystal for inducing phosphorus in sewage so as to recycle phosphorus in a form of hydroxyl calcium phosphate crystals, and the recycled product can be directly applied to industrial and agricultural production, so that the sewage treatment, the environmental protection and the resource reutilization are organically combined. Besides, the method has the characteristics of small occupied area, high recycling efficiency, good quality of the recycled product, little equipment investment and convenient operation.

A surface activation method of a dental implant comprises: putting a titanium implant in 1-3M of H2SO4 liquid, using the titanium or titanium alloy of the titanium implant as an anode and using a Pt material as a cathode to carry out anode oxidation by using an anode oxidation method, preparing an oxidation film with a three-dimensional spherical pore microstructure on a surface, and existing round pits in different sizes and with apertures of 100-200nm in local areas; and putting the titanium implant with the oxidized anode in 3-5M of NaOH alkali solution for processing and forming a titanium gel on the surface, wherein the enriched Ti-OH groups induce the generation of calcium phosphate crystal nucleuses to form a bone-like apatite layer. The invention uses the combination of the anode oxidation method and an alkali process method for preparing an active TiO2 coating layer on the surface of the titanium alloy, the implant processed by the anode oxidation method has good compatibility with bone, and bonding strength and bone sediment yield are both obviously higher than that of the unprocessed titanium, thereby greatly improving the clinic success ratio of the dental implant.

The invention discloses mineralized corn protein fibrous membrane which is formed by the irregular accumulation of nano-fiber containing an organic component and mineral, wherein the organic component is corn protein or corn protein containing additive, and the mineral is calcium phosphate crystal. The diameter of the corn protein fiber or corn protein fiber containing additive is 20 nanometers to 10 microns, and the pore size of the fibrous membrane is 100 nanometers to 100 microns. A preparation method of the mineralized corn protein fibrous membrane comprises the following steps: dissolving the corn protein in a solvent; and performing electric spinning to prepare the fibrous membrane of irregular accumulation; sequentially soaking the prepared fibrous membrane in acetic acid solution, calcium ion-containing solution and phosphate radical-containing solution for certain time, wherein the molar ratio of the calcium ions to the phosphate radical ions is (1:2)-(3:1); and repeatedly soaking, washing and freeze-drying the fibrous membrane to obtain the mineralized corn protein fibrous membrane.

The invention discloses a corrosion and scale inhibitor for the reuse of reclaimed water from production wastewater as circulating cooling water, which comprises the following raw materials by weight: an organic phosphonic acid corrosion and scale inhibitor, PBTC, KW-923, a copper corrosion inhibitor, and deionized production water; the corrosion and scale inhibitor is based on the high-efficientdispersant of KW-923, and is combined with other components such as organic phosphonic acid and copper corrosion inhibitors; through the adsorption and chelation with inorganic scaling microcrystals such as calcium carbonate and calcium phosphate, and organic microparticles in water, the invention can effectively prevent calcium carbonate and calcium phosphate crystals and organic particles from scaling, effectively reduce the corrosion rates of carbon steel and copper, and has good effect of scale inhibition and corrosion inhibition.

The invention discloses a preparation method of a nano-silver antibacterial agent, and belongs to the field of antibacterial technology. Activated carbon is crushed and then mixed with phosphorus pentoxide, mixture is dispersed in absolute ethyl alcohol, the phosphorus pentoxide is dissolved in the ethyl alcohol to form phospholipid, the phospholipid is adsorbed on the surface of the activated carbon, calcium nitrate is slowly combined with hydroxy on a phospholipid hydrolysis product to form hydroxy calcium phosphate crystal nucleuses, the hydroxy calcium phosphate crystal nucleuses are adsorbed in pore structures of the activated carbon, agglomeration is avoided, the crystal nucleuses are washed, dried and then calcined, activated carbon cores are removed to obtain calcined materials with porous structures, the calcined materials serve as carriers, glucose serves as a reducing agent for reducing silver-ammonia solution, and generated nano-silver particles are adsorbed by the calcined materials with the porous structures, finally filtered, washed and dried in vacuum to obtain the nano-silver antibacterial agent. The nano-silver antibacterial agent is good in stability and uniform in dispersion in the use process and has high antibacterial endurance.

The invention discloses a dispersing agent for reusing reclaimed water prepared from production wastewater as circulating cooling water and a preparation method of the dispersing agent through a copolymerization method. The dispersing agent is a mixture with multiple active groups and produced by multi-component copolymerization reaction; calcium carbonate and calcium phosphate crystals and organic microparticles can be effectively prevented from forming deposited scale through the adsorption and chelation effects between the dispersing agent and inorganic scaling microcrystals in water, such as calcium carbonate and calcium phosphate as well as the organic microparticles; the dispersing agent specifically meets the characteristics that the reclaimed water obtained after wastewater treatment is high in hardness and high in base and contains multiple complex organic matters, and effectively takes good scale inhibition and dispersion effects on a circulating water system for reclaimed water recycling, thereby obtaining good and long-acting treatment effect.

The object of the present invention is to provide a calcium phosphate-collagen fiber composite which has an excellent mechanical property, can induce bone replacement by rapid bone remodeling, and can be used in a high-load region. The object can be solved by a porous composite comprising a calcium phosphate crystal and a collagen fiber at a weight ratio of 80:20 to 20:80, wherein (1) a bioabsorbability of the porous composite is graded, and (2) the density of the porous composite determined by gravimetric method is 300 to 1500 mg / cm3.

In an embodiment of the present disclosure, there is provided a composition for inhibiting calcium oxalate crystal growth. In an embodiment of the present disclosure, there is provided a composition for inhibiting calcium phosphate crystal growth. In some embodiments, such a composition comprises at least one citrate derivative of an organic acid and at least one pharmaceutically acceptable carrier. In another embodiment, the present disclosure relates to a method of controlling calcium oxalate crystal growth in a subject in need thereof. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease. In an embodiment, the method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition.

The invention belongs to the technical field of environmental chemistry, and in particular relates to a coating modification one-step in-situ synthesis method of calcium phosphate-based composition anti-corrosion pigment. By adoption of the coating modification one-step in-situ synthesis method, a phosphate radical and calcium ions are cleverly utilized to perform reaction, and heat released by the process of generating calcium phosphate increases the temperature of a reaction system, so that the solubility of the benzotriazole and the solubility of a surface treating agent are greatly improved; and the dissolved benzotriazole and the dissolved surface treated agent are attached to the surface of a calcium phosphate crystal nucleus, the growth of a calcium phosphate crystal is effectivelyinhibited, the particle size is controlled to a nanometer scale, the added surfactant achieves the surface treating effect, and the compatibility of the anti-corrosion pigment and the coating system is improved; after the reaction of the calcium phosphate and sodium phosphate, the temperature of the reaction system is reduced, the solubility of the benzotriazole and the solubility of the surface treating agent are reduced along with the reduction of the temperature, the benzotriazole and the surface treating agent are separated out of the system and are firmly coated on the surface of the calcium phosphate nano-crystal, the calcium phosphate-based composite anti-corrosion pigment with fixed composition and a stable structure is finally obtained, and the obtained product has the characteristics of high dispersibility, small particle size, excellent corrosion resistance and the like.

The invention belongs to the technical field of tendon patch materials, and particularly relates to a bionic natural tendon-bone gradient interface patch material and a preparation method thereof. The patch material is medical nanofibers of which the surfaces are covered with calcium phosphate crystals, and the fiber arrangement mode of the nanofibers is gradually transited from uniaxial orientation arrangement at one end to irregular arrangement at the other end, and calcium phosphate crystals are gradually reduced from the irregular arrangement end to the uniaxial orientation arrangement end; and the preparation method comprises the following steps of preparing a uniaxial orientation nanofiber membrane by taking a medical fiber material and a near-infrared dye as raw materials; gradually converting uniaxial orientation arrangement into irregular arrangement through laser irradiation at different time; then vertically placing in a culture dish, enabling the end with the longest irradiation time to face downwards, and dropwise adding simulated body fluid to obtain the bionic natural tendon-bone gradient interface patch material. The patch material provided by the invention has orientation structure and mineralization dual-gradient change, has excellent elasticity and good mechanical properties, and can meet the biomechanical strength and compliance required by an in-vivo microenvironment.

The invention discloses a co-doped nano-calcium phosphate antibacterial material containing cations and anions and a preparation method of the co-doped nano-calcium phosphate antibacterial material. Acalcium phosphate crystal structure is doped with anionic fluorine, gamma-PGA and cationic copper, zinc, magnesium or silver ions, so as to obtain the co-doped nano-calcium phosphate antibacterial material containing the cations and the anions. The pH value is circularly adjusted, a small amount of Cr<3+> is added into a gamma-PGA solution so as to prepare a gamma-PGA modifying agent, and gamma-PGA binds with Ca<2+> on calcium phosphate crystals so as to prepare anionic and cationic co-doped nano-calcium phosphate containing fluorine ions, gamma-polyglutamic acid and metal ions, the nano-calcium phosphate has a good antibacterial property and has multiple biological characteristics of being capable of regulating and controlling degradation rates of the metal ions and the fluorine ions, improving infection resistance and promoting blood vessel regeneration and bone formation.

The invention relates to a method for recovering sludge phosphorus from an urban sewage treatment plant, belonging to the technical fields of sludge treatment and resources. The method comprises the following steps: respectively carrying out gravity thickening on sludge releasing sludge phosphorus, sludge phosphorus releasing on sludge after the gravity thickening, solid-liquid separation on sludge after the sludge phosphorus releasing, sludge phosphorus recovery on supernatant fluid rich of phosphorus after the solid-liquid separation, and the like; the sludge phosphorus releasing on sludge after the gravity thickening is realized by treating the sludge by an acidification and normal-pressure microwave radiation combination method; and the sludge phosphorus recovery on supernatant fluid rich of phosphorus after the solid-liquid separation is realized by treating the supernatant fluid rich of phosphorus by a calcium phosphate crystallization process to obtain the deposit containing calcium phosphate crystal, then filtering the deposit containing calcium phosphate crystal and finally recovering the sludge phosphorus. The method not only can efficiently recover the phosphorus in thesludge from the urban sewage treatment plant, but also can achieve the aims of reducing the sludge and improving the depositing performance of the sludge.

The object of the present invention is to provide a calcium phosphate-collagen fiber composite which has an excellent mechanical property, can induce bone replacement by rapid bone remodeling, and can be used in a high-load region. The object can be solved by a porous composite comprising a calcium phosphate crystal and a collagen fiber at a weight ratio of 80:20 to 20:80, wherein (1) a bioabsorbability of the porous composite is graded, and (2) the density of the porous composite determined by gravimetric method is 300 to 1500 mg / cm3.

The invention provides thermoplastic materials for biomedical applications through the processing of soybean de-fatted Tofu cheese. The material films show a relatively high degree of water uptake from the dry state as well as good tensile strength and elastic modulus when tested in wet conditions. The materials minimise in vitro the humoral and cell-mediated inflammatory response, promote the formation of calcium phosphate crystals and undergo a slow degradation in buffer systems. Adhesion and proliferation of tissue cells are favoured by this natural composite material.

Methods for determining whether certain compounds, in particular crystals, are present in a sample of a biological fluid that indicates an individual has a particular disease or condition, such as but not limited to gout, pseudogout or urinary tract stones. In some embodiments, the methods include the steps of digestion and filtration of a sample of synovial fluid in order to isolate, if present, monosodium urate monohydrate (MSU), calcium pyrophosphate dihydrate (CPPD), or calcium phosphate crystals from the sample, wherein the filtrate is analyzed with a Raman device to ascertain the presence and type of the crystals. Devices for performing steps of the method are disclosed.

The invention discloses a controllable preparation method of modified hydroxyapatite powder based on microfluidic control. A micro-channel chip with a Y-shaped structure is used as a reaction container; mineral oil / oleic acid / Span-80 is used as an oil phase containing an emulsifier; an inorganic calcium ion / sodium polyacrylate aqueous solution and an ammonia water / phosphate ion aqueous solution are used as aqueous phases, calcium phosphate crystal nucleuses are formed in the micro-flow droplets and further grow to spherical / shuttle-shaped hydroxyapatite nano particles, the obtained hydroxyapatite nano particles are controllable in particle size, and the particle size of the hydroxyapatite nano particles ranges from 3 nm to 80 nm. The prepared hydroxyapatite nano particles have high dispersity and good biocompatibility, and can be applied to multiple fields of cosmetic sun-screening agents, abrasives, concealer, and the like.

The invention provides a lipase-calcium phosphate compound enzyme crystal, a preparation method thereof and a method for catalyzing and synthesizing clindamycin palmitate by using the lipase-calcium phosphate compound enzyme crystal, and belongs to the technical field of antibiotic drug synthesis. According to the method, clindamycin free alkali shown in the formula I and ethenyl hexadecanoate shown in the formula II serve as a substrate and react with a reaction solvent for 6-30 h at the temperature of 30-80 DEG C under the catalytic function of the lipase-calcium phosphate compound enzyme crystal, and clindamycin palmitate shown in the formula III is prepared. The lipase-calcium phosphate compound enzyme crystal prepared through the method is a calcium phosphate crystal of thermomyces lanuginosus lipase. The lipase-calcium phosphate compound enzyme crystal has the advantages that the cost of the method is low, immobilized enzyme cannot be dissolved in an organic solvent and can be recycled, the yield can reach 75.8% at most, the method is safe, reliable, low in environment pollution and suitable for industrial production.

Methods for determining whether certain compounds, in particular crystals, are present in a sample of a biological fluid that indicates an individual has a particular disease or condition, such as but not limited to gout, pseudogout or urinary tract stones. In some embodiments, the methods include the steps of digestion and filtration of a sample of synovial fluid in order to isolate, if present, monosodium urate monohydrate (MSU), calcium pyrophosphate dihydrate (CPPD), or calcium phosphate crystals from the sample, wherein the filtrate is analyzed with a Raman device to ascertain the presence and type of the crystals. Devices for performing steps of the method are disclosed.

The invention discloses an amorphous calcium phosphate-polyacrylic acid hybridized nano material and a preparation method and application thereof, and belongs to the field of biomedical materials. Under synergistic stable effects of polyacrylic acid molecules and magnesium ions, the amorphous calcium phosphate-polyacrylic acid hybridized nano material is prepared by a wet chemistry method. The doped polyacrylic acid molecules can be complexed with calcium ions, the polyacrylic acid molecules and magnesium ions jointly stop formation of crystals. Compared with an existing calcium phosphate crystal material, the amorphous calcium phosphate-polyacrylic acid hybridized nano material is degraded more quickly, and can be used for coated carriers of functional molecules such as genes and drugs. For example, if the amorphous calcium phosphate-polyacrylic acid hybridized nano material coats fluorescent molecules (such as fluorescein isothiocyanate and indocyanine green) in a hybrid material, afluorescent developing effect can be achieved. Compared with a traditional fluorescent developing agent, the amorphous calcium phosphate-polyacrylic acid hybridized nano material coats the fluorescentmolecules, has a function of rapidly releasing the fluorescent molecules in a weak acid environment, and is a fluorescent carrier with quite good biological compatibility.

The invention discloses a corrosion and scale inhibitor for the reuse of reclaimed water from production wastewater as circulating cooling water, which comprises the following raw materials by weight: an organic phosphonic acid corrosion and scale inhibitor, PBTC, KW-923, a copper corrosion inhibitor, and deionized production water; the corrosion and scale inhibitor is based on the high-efficientdispersant of KW-923, and is combined with other components such as organic phosphonic acid and copper corrosion inhibitors; through the adsorption and chelation with inorganic scaling microcrystals such as calcium carbonate and calcium phosphate, and organic microparticles in water, the invention can effectively prevent calcium carbonate and calcium phosphate crystals and organic particles from scaling, effectively reduce the corrosion rates of carbon steel and copper, and has good effect of scale inhibition and corrosion inhibition.

Methods for determining whether certain compounds, in particular crystals, are present in a sample of a biological fluid that indicates an individual has a particular disease or condition, such as but not limited to gout, pseudogout or urinary tract stones. In some embodiments, the methods include the steps of digestion and filtration of a sample of synovial fluid in order to isolate, if present, monosodium urate monohydrate (MSU), calcium pyrophosphate dihydrate (CPPD), or calcium phosphate crystals from the sample, wherein the filtrate is analyzed with a Raman device to ascertain the presence and type of the crystals. Devices for performing steps of the method are disclosed.

The invention discloses a synthesis method of a glycolic acid polymer and a derivative thereof, which comprises the following steps: carrying out polymerization reaction on glycolic acid serving as a monomer raw material to generate polymeric glycolic acid, and forming a ternary composite efficient scale inhibitor by taking the polymeric glycolic acid, citric acid and aspartic acid as raw materials; the scale inhibitor can be complexed with calcium ions in circulating water and adsorbed on the surfaces of calcium carbonate, calcium sulfate, calcium phosphate and other crystals, so that the calcium carbonate, calcium sulfate and calcium phosphate crystals are distorted into loose structures and are removed along with water flow, the formation of calcium carbonate, calcium sulfate and calcium phosphate scales is eliminated and inhibited, and the formed calcium carbonate, calcium sulfate and calcium phosphate scales can be removed. The agent is a phosphorus-free agent, so that the total phosphorus of discharged circulating water cannot exceed the standard; the scale inhibitor has a good scale inhibition effect on calcium carbonate, calcium sulfate and calcium phosphate, the running concentration ratio of a circulating water system is remarkably increased to 8 times or above, it is guaranteed that the circulating water system does not scale, and the scale inhibitor has remarkable water-saving and energy-saving effects.

The invention discloses a moisture-proof treatment process for a gypsum-based building material product by utilizing industrial waste acid, and belongs to the field of building materials. Aiming at the characteristics that the gypsum-based building material product is not resistant to water and low in softening coefficient, a process route of soaking in a phosphoric acid solution twice and soaking in saturated lime water twice is adopted, and a layer of insoluble calcium phosphate crystals is generated in pores and the surface of the gypsum-based building material product. On one hand, insoluble calcium phosphate crystals can hinder the dissolution effect of water on calcium sulfate, and on the other hand, gypsum pores can be filled, so that the aim of improving the strength and water resistance of gypsum is achieved. The technical route is simple, the raw materials are mainly industrial waste acid, the method is green and environment-friendly, the economic benefit is prominent, and the water resistance of the gypsum-based building material product can be effectively improved.

The invention provides an enzyme / calcium salt / GO (graphene oxide) functional nanocomposite and a preparation method thereof. The nanocomposite is prepared from components in percentage by mass as follows: 20%-40% of bio-enzyme, 32%-70% of calcium phosphate crystals and 5%-30% of GO. A dynamic reaction method is adopted, violent experiment methods such as high temperature are not required, no organic reagents are involved, the method conforms to the green and environmental protection route, the obtained enzyme / calcium salt / GO functional nanocomposite has a regular structure, immobilized enzyme activity, thermal stability and storage stability are improved under the condition that enzyme conformation and GO nanostructures are not damaged, and meanwhile, the nanocomposite has certain antibacterial and adsorption performance and can be widely applied to antibacterial composites and adsorption composites.