149results about How to "Mass transfer rate is fast" patented technology

The invention discloses a method for extracting total flavonoids in grape seeds in a double-aqueous phase system, belonging to the field of separation and extraction methods of natural product active ingredients. The method comprises the following steps of: firstly preparing grape seed rough extract from grape seeds with ethanol; then adding absolute ethyl alcohol, ammonia sulfate, inorganic salt and water in the grape seed rough extract to form the double-aqueous phase system, mixing uniformly, standing for 5-30 minutes at room temperature for delamination to obtain an upper phase and a lower phase, concentrating the upper phase through pressure reduction and drying so as to obtain total flavonoids of grape seed. In the double-aqueous phase system, the mass percents of grape seed rough extract, absolute ethyl alcohol, ammonia sulfate and inorganic salt are respectively 5% to 30%, 10% to 30%, 16% to 30%, and 0 to 5%, the balance is supplemented to be 100% with water, and the pH of the double-aqueous phase system is 3.0 to 11.0. Flavonoids are extracted by utilizing double aqueous phases in the method; the method is simple, the operation is convenient, the production cost is low and the treating capacity is large, small test data can be directly amplified, and the yield of flavonoids in the grape seeds reaches up to 98.2%; and the method can be operated continuously, and is suitable for industrialized production of flavonoids in the grape seeds.

The invention provides a method for performing extraction separation on cobalt and nickel by using a microfluid technology. The method comprises the following steps of: uniformly mixing an extraction agent and diluent which are subjected to homogeneous phase saponification by using a mixed material liquid of Co<2+> and Ni<2+>, using 2-ethyl cthylhexyl phosphonate mono 2-ethyl cthylhexyl ester as the extraction agent and using No.260 solvent oil and using the extraction agent and the diluent as an oil phase; introducing the water phase and the oil phase into a micro-reactor by virtue of two flow pumps; mixing the two phases in the micro-reactor and performing extraction reaction at 25-50 DEG C; and collecting a product at an outlet of the micro-reactor and standing for separating the phases to ensure that Co<2+> enters the oil phase and Ni<2+> stays in the water phase so as to realize extraction separation of cobalt and nickel. According to the method, continuous flow micro-reactor with an enhanced hybrid channel structure is adopted, the extraction separation of cobalt and nickel is carried out, and the reaction time is shortened to be within a micro-second level range, so that single-level cobalt extraction efficiency is obviously improved, and the extraction levels are reduced; and moreover, standing layering on the water phase and the oil phase can be quickly carried out without any emulsion phenomenon.

The invention discloses a microwave-assisted Soxhlet and solid-phase extraction coupling device, a microwave-assisted Soxhlet and solid-phase extraction coupling method and application of microwave-assisted Soxhlet and solid-phase extraction coupling. The microwave-assisted Soxhlet and solid-phase extraction coupling device comprises a microwave-assisted extractor, a Soxhlet extractor, solid-phase adsorbents, an extraction bottle, a reflux condensing pipe and the like, and extraction and purification are synchronously completed by means of coupling microwave-assisted Soxhlet extraction and solid-phase extraction. When in extraction, the solid-phase adsorbents are filled into a Soxhlet extraction device, the extraction bottle is directly placed in the microwave-assisted extractor for extraction after extraction solvents are added into the extraction bottle, analytes are collected into the extraction solvents, and interfering components in samples are adsorbed by the solid-phase adsorbents. High efficiency of microwave-assisted extraction, universality of Soxhlet extraction and high selectivity of solid-phase extraction are combined, the device is simple and convenient in operation, is conveniently used with an analysis instrument, and is suitable for extraction and purification of trace organics in complicated samples.

The invention relates to a method for synthesizing cyclic carbonate ester in a micro reactor system, which comprises the following steps of: firstly mixing a liquid material containing an epoxy compound and a catalyst with a gas material containing carbon dioxide in a micro mixer, and then synthesizing cyclic carbonate ester in a micro channel reactor through a cyclization reaction. For the method, the reaction temperature is 100-220 DEG C, the pressure is 1.0-7.0 MPa, the molar ratio of carbon dioxide to epoxy compound in the gas-liquid two-phase material is 1.0-5:1, the mass ratio of the epoxy compound to the catalyst is 1.0-1000:1, and the retention time of the gas-liquid two-phase material in the micro channel reactor is 1.0-300 s. The reaction system has quick mass transfer and heat transfer rates, continuous process, easiness in control, high process safety and high energy utilization ratio, and the space-time yield and the selectivity of the target product can be greatly increased.

The invention discloses a polymer brush graft boracic acid affinity separation material and a preparation method and application, which use a reversible-addition fragmentation chain transfer (RAFT) polymerization method, use amide compounds with phenylboronic acid groups as monomers, wherein the amide compounds are polymerized on the surfaces of polyacrylic acids, silica gels, agarose and magnetic nanoparticles to obtain the polymer brush graft boracic acid affinity separation material. The polymer brush graft boracic acid affinity separation material has the advantages of high adsorption capacity, excellent selectivity and rapid mass transfer rate, can be used for preparation, separation and content analysis of biomolecules containing cis vicinal diols, and can greatly improve separation enrichment efficiency.

A process for effectively preparing the theapolyphenol includes mixing fresh tea leaves with solvent, homogenizing, solid-liquid extracting, filtering, mixing dregs with solvent, solid-liquid extracting, collecting the liquid extract, concentrating, mixing with dichloromethane solution, liquid-liquid extracting, centrifugal treating, mixing the liquid extract with ethyl acetate, liquid-liquid extracting, centrifugal treating, filtering, concentrating, drying and purifying. Its advantages are short period and high output rate.

The invention relates to a vibrating screen plate tower for continuous production of liquid-liquid-liquid three-phase extraction. A cylindrical tower body comprises a light-phase clarification outer tank connected to the upper part of the cylindrical tower body and a tower bottom clarification tank connected to the lower part; a spindle leads to the lower part of the cylindrical tower body from the exterior of the light-phase clarification outer tank; the upper part and the lower part of the cylindrical tower body are provided with a conical liquid baffle and a light-phase distributor which are arranged on the spindle respectively; a middle screen plate is arranged in the middle of the spindle; a heavy-phase guide cylinder is arranged inside the light-phase clarification outer tank; a heavy-phase mixing chamber is arranged inside the heavy-phase guide cylinder; a bottom liquid outlet of the heavy-phase guide cylinder is positioned at the conical liquid baffle; a polymer phase distributor and an aqueous phase distributor are arranged on a polymer phase conduit and an aqueous phase conduit in the heavy-phase mixing chamber; a tower top screen plate is fixedly arranged on the spindle in the heavy-phase mixing chamber; a sealing ring is arranged between the spindle and the heavy-phase mixing chamber; and two layers of deflection baffles which are arranged in a staggered mode are fixedly arranged on the spindle in the tower bottom clarification tank. The vibrating screen plate tower has high mass transfer efficiency and high controllability.

The invention discloses an on-line coupling system for a dynamic liquid-liquid solid imprinted microextraction-liquid phase chromatogram, which comprises a magnetic agitator, a water bath bottle, an extracting bottle, a draft tube, a peristaltic pump, a high-pressure six-way switching valve, a molecularly imprinted solid phase extracting material, a high-pressure six-way sample valve, a quantifying cup, a sample needle, a liquid phase chromatographic pump, a chromatographic column, a detector, a liquid phase chromatogram and the like. Through the coupling of a dynamic liquid-liquid solid imprinted microextracting device and the liquid phase chromatogram, the on-line overall processes of the preenrichment, the extraction, the desorption, the separation and the detection of a target analytein a water phase sample are achieved. By using the system, the universality of liquid-liquid extraction, the high selectivity and the high enrichment capability of a molecularly imprinted solid phasemicroextraction technique, the efficient separation capability and the high sensitivity of the liquid phase chromatogram are combined; the analysis degree of automation is improved; the analysis timeis shortened; the accuracy and the precision are improved; and the system can be effectively applied to the analysis and the detection of a trace organic matter in a complicated sample.

The invention discloses a polydopamine coated magnetic Fe3O4 molecularly imprinted polymer, a preparation method thereof and application of the polydopamine coated magnetic Fe3O4 molecularly imprintedpolymer. The invention also discloses an electrochemical sensor based on the polydopamine-coated magnetic Fe3O4 molecularly imprinted polymer, a preparation method of the electrochemical sensor and application of the electrochemical sensor. According to the polydopamine coated magnetic Fe3O4 molecularly imprinted polymer, the preparation method thereof, the application of the polydopamine coatedmagnetic Fe3O4 molecularly imprinted polymer, the electrochemical sensor based on the polydopamine-coated magnetic Fe3O4 molecularly imprinted polymer, the preparation method of the electrochemical sensor and the application of the electrochemical sensor of the invention, Fe3O4 is used as a carrier, molecular imprinting is directly carried out on the surface of the Fe3O4, and therefore, a complexsurface modification process is simplified. DDT recognition, extraction and separation performed a target compound have the advantages of specificity, simple steps, high efficiency and the like; a surface molecular imprinting technology is combined with electrochemical impedance spectroscopy (EIS), so that the constructed electrochemical impedance sensor integrates the advantage of selectivity ofthe molecular imprinting and the advantage of high sensitivity of the EIS.

The invention discloses a graphene oxide doped molecular imprinted polymer stirring rod as well as a preparation method and application thereof. The graphene oxide doped molecular imprinted polymer stirring rod comprises a glass capillary tube, an iron core and an extraction coating; the iron core is arranged in the glass capillary tube with two hotly-sealed ends; and the extraction coating is a graphene oxide doped propranolol molecular imprinted polymer coating which is chemically bonded on the surface of the glass capillary tube. According to the graphene oxide doped molecular imprinted polymer stirring rod, a glass stirring rod which is activated by a sodium hydroxide solution is immersed into a mold containing a graphene oxide doped molecular imprinted prepolymerization solution; and after reaction is finished, the graphene oxide doped molecular imprinted polymer coating stirring rod is taken out. The graphene oxide doped molecular imprinted polymer stirring rod disclosed by the invention can be used for selectively extracting and analyzing medicines, and has the advantages of strong water-phase identification capability, good extraction selectivity, high adsorption capacity, rapid mass transfer rate, good mechanical stability, good heat stability, good chemical stability and the like.

The invention discloses a polymer-supported dual-core acid ion liquid catalyst and preparation and application thereof. According to the polymer-supported dual-core acid ion liquid catalyst, vinylbenzyl chloride and vinyl benzene serve as polymeric monomers, divinyl benzene serve as cross-linking agent, polymers obtained through free radical polymerization serve as carriers, bis(2-chloroethyl) amine, benzimidazole, 1, 3-propane sultone and concentrated sulfuric acid or trifluoromethanesulfonic acid serve as the raw materials, and through a bonding method, effective immobilization of ionic liquid onto polymeric microspheres can be achieved. The polymer-supported dual-core acid ion liquid catalyst blends the advantages of the ionic liquid and polymers and has the advantages of being large in specific surface area, adjustable in pore structure, high in hydrophobicity, simple in preparation method, high in catalytic activity and mass transfer rate, good in selectivity, high in stability, easy to recover and separate, environmentally friendly, broad in industrialized application prospect and the like. When applied to esterification reaction of various acids and alcohols, the polymer-supported dual-core acid ion liquid catalyst can achieve good effects.

The invention provides an environmentally-friendly transport vehicle for fresh and live aquatic products. The environmentally-friendly transport vehicle comprises a carriage, a solar cooling system isarranged on the carriage, the carriage is internally provided with keep-alive boxes with a water cycle device, and a solar power system used for power supply is provided; the water cycle device comprises a water pump, a water inlet of the water pump is communicated with the keep-alive boxes, a water outlet of the water pump is connected with a filtering and sterilization box, the filtering and sterilization box is connected with a cool-heat-exchanger through a foam separation device, the cool-heat-exchanger is communicated with the keep-alive boxes, and the water pump is connected with a controller. According to an inner-box environment monitoring system of the transport vehicle, optical fiber sensors are applied to measurement of oxygen, the temperatures and ammonia-nitrogen in water inan aquatic product transporting process, so that the transport environments of the aquatic products are accurately monitored in real time; according to the transport vehicle, the multiple keep-alive boxes are independently controlled, and the appropriate environments are provided for each kind of aquatic products, so that the transporting keep-alive rate of the fresh and live aquatic products is effectively improved.

The invention discloses nucleic acid aptamer-molecular imprinting synergistic recognition magnetic microspheres and a preparation method and application thereof. The nucleic acid aptamer-molecular imprinting synergistic recognition magnetic microspheres disclosed by the invention comprise magnetic microsphere inner cores and nucleic acid aptamer-molecular imprinting synergistic recognition shells;the nucleic acid aptamer-molecular imprinting synergistic recognition shells have molecular imprinting polymer rigid recognition cavities; the molecular imprinting polymer rigid recognition cavitieshave structural stability, difficult deformation and strong specific adsorptivity; and nucleic acid aptamers are not easy to digest.

The invention discloses a novel continuous automated reaction process for preparing an aminopolycarboxylic acids chelating agent and belongs to the technical field of aminopolycarboxylic acids chelating agents. Production is conducted through a flow reactor, a whole reaction system is under DCS automation control, and the process comprises the following steps: 1, material blending and mixing, wherein raw materials are continuously and stably pumped into a batcher for mixing, so that a liquid mixture is obtained; 2, preheating treatment, wherein the liquid mixture is pumped out of the batcher through a material delivering pump, and the liquid mixture which is pump out is subjected to heating treatment through a heater; 3, reaction and generation, wherein heated liquid materials and formaldehyde or heated liquid materials and a glycolonitrile solution are added into the reactor for a reaction, ammonia gas generated through the reaction is discharged through the top of the reactor and collected, and a reaction solution is drained through the bottom of the reactor and delivered to the acidification procedure for after-treatment through the material delivering pump, so that the aminopolycarboxylic acids chelating agent is obtained. By means of the process, the aminopolycarboxylic acids chelating agent can be produced in a continuous and automated mode, and stability of the reaction process is improved.

The invention relates to a device and a method for recovering and concentrating ortho-toluidine in ortho-toluidine wastewater by membrane extraction. The method comprises: conveying wastewater containing ortho-toluidine to a silicon rubber extraction membrane tube, wherein the silicon rubber extraction membrane tube is put in an acidic extraction solution, ortho-toluidine in the wastewater can penetrate through the tube wall of the silicon rubber extraction membrane tube, enter into the extraction solution and react to generate ortho-toluidine ions, and the rest of the wastewater is discharged from the outlet of the silicon rubber extraction membrane tube with standard level or post-treatment; and taking out the extraction solution when the concentration of the ortho-toluidine ions in the extraction solution exceeds a predetermined value, and adding alkali liquor into the extraction solution to obtain recovered and concentrated ortho-toluidine. According to the device and method provided by the invention, the extraction solution is acidic and is reacted with alkalescent ortho-toluidine to generate the ortho-toluidine ions which cannot penetrate through the silicon rubber extraction membrane tube so as to prevent the ortho-toluidine from returning to the wastewater again. A lot of ortho-toluidine can be separated and concentrated, the mass transfer velocity is relatively rapid, industrial treatment and concentration and recovery of the ortho-toluidine are facilitated, and the use level of the extraction solution is extremely little.

An anti-micellar method for degradating cellulose includes dissolving cellulase in buffering liquid, preparing the organic solution of surfactant, mixing them together, adding microcrystalline cellulse, phosphoric acid buffering liquid and extractant, strong waving, centrifugal layering, and taking the upper soluiton, laying to obtain glucose solution.

The invention discloses a preparation method and application of aptamer-modified chitosan nano fibers. The preparation method comprises the following steps: (1) preparing a chitosan solution; (2) preparing chitosan nano fibers; (3) chemical immobilization: taking the aptamer solution, adding an EDC/NHS (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide/N-hydroxysuccinimide) solution for activation, adding the chitosan nano fibers obtained in the step (2), and oscillating to react at normal temperature; and (4) after-treatment: carrying out solid-liquid separation on the reaction mixed solution obtained in the step (3) to obtain the aptamer-modified chitosan nano fibers. The aptamer-modified chitosan nano fibers are suitable for high-selectivity separation and enrichment of trace or ultra-trace mycotoxin substances and other substances in the food and environment, and have the advantages of high selectivity, high extraction capacity, high stability and simple preparation process.

The invention provides a method for continuously catalytically degrading lignin bio-oil into aromatic hydrocarbons and naphthenes by using a microchannel reaction device, comprising the following steps: (1) in an alcohol solvent, using an alkali catalyst to catalyze the hydrogenation depolymerization of lignin into Phenolic bio-oil; (2) filter and remove the alkali catalyst in the phenolic bio-oil, phenolic bio-oil and hydrogen are pumped into the microstructure mixer respectively simultaneously, after mixing evenly, react in the microchannel reactor, described microchannel reactor The channel reactor is filled with a bifunctional catalyst to hydrocrack the phenolic bio-oil into aromatic hydrocarbons or cycloalkanes; (3) extracting aromatic hydrocarbons or cycloalkanes from the reaction liquid.