89results about How to "Raw material economy" patented technology

An expansion-type flame-retarding material is prepared through reaction between polyol and phosphorus compound containing hydroxy, adding melamine, reaction and modifying surface by high-molecular substance. Its advantages are high compatibility to polyethene and polypropyene, less consumption, high mechanical performance and flame-retarding effect, no poison and corrosion, and environment friendly.

The present invention relates to superfine magnetic carrier particle with compound function and its preparation process. It is a kind of complex with three-layered core-shell structure including the first layer of ferric oxide, the second layer of polymer carrier material and the third layer of bioactive functional preparation. It has the compound functions of magnetic positioning, biological targeting positioning and controlled medicine release. The preparation process includes the following steps: preparing of super-paramagnetic superfine particle, covering the superfine carrier particle with bioactive functional preparation via physical coagulation and chemical linkage. The preparation process can prepare superfine magnetic carrier particle with compound function in 40-80 nm size and with narrow size distribution, good targeting property, controlled medicine release and thus important application foreground in local medicinal treatment and diagnosis carrier preparation.

The invention discloses a method for preparing 5-hydroxymethyl furfural and 2,5-furandimethanol simultaneously. According to the method, the 5-hydroxymethyl furfural and the 2,5-furandimethanol can be prepared simultaneously through performing Cannizzaro reaction to the 5-hydroxymethyl furfural (5-HMF). Compared with the previous methods, the method of the invention does not need extra oxidant, reducing agent and expensive metal catalyst, has the advantages of low production equipment requirement, safe production technology, moderate reaction condition, high reaction efficiency and economic atom, can obtain two products at the same time, and accords with the current green chemical technology and the requirement for product diversified production.

The invention discloses a compound photocatalyst formed by co-modifying TiO2 by silver and graphene. The compound photocatalyst is prepared from the following steps: (1) dispersing graphene oxide in water to obtain a graphene oxide dispersion solution; (2) dissolving AgNO3 in water to obtain an AgNO3 solution; (3) mixing the graphene oxide dispersion solution, the AgNO3 solution, TiO2 powder and sodium citrate and uniformly dispersing the mixture; (4) transferring the mixture obtained in the step (3) to a hydrothermal kettle, and raising the temperature for a hydrothermal reaction; and (5) after the reaction, cooling the mixture to room temperature and washing and drying the same. The preparation method of the compound photocatalyst is simple and feasible and economic in raw material, doesnot generate toxic and harmful substances, can degrade formaldehyde in air under irradiation of visible light, and can be used repeatedly.

The invention discloses an application of a compound to preparation of medicines for treating viral pneumonia, and relates to the technical field of drugs. The technical problem that novel antiviral drugs are deficient in the prior art, can be solved. The compound comprises a purine compound adopting the structure as shown in the formula 1, and / or an anthraquinone derivative adopting the structureas shown in the formula 2. The purine compound adopting the structure as shown in the formula 1, and / or the anthraquinone derivative adopting the structure as shown in the formula 2 both can show predominant effect for resisting viral pneumonia when being separately used or used jointly. Drugs for treating viral pneumonia, are prepared by the compound provided by the invention are more notable inactivity compared with clinical frontline drugs, and are better than drugs of ribavirin, oseltamivir and the like.

The invention relates to a method for preparing monodisperse silver nanocrystals. The method of the invention comprises the steps that (1) 0.1 to 1g silver nitrate is added into 10 ml. octadecylamine solvent to react for 1 to 10 min; (2) sediments after the reaction are washed by ethanol and then dried to obtain the monodisperse silver nanocrystals. In the step (1) of the preparation method, sulphur powder can be further added into the reaction system to continue to react for 8 to 12 min so as to obtain the monodisperse silver sulfide nanocrystals or selenium powder can be further added into the reaction system to continue to react for 8 to 12 min so as to obtain the monodisperse silver selenide nanocrystals. The method for preparing the monodisperse silver nanocrystals, the monodisperse silver sulfide nanocrystals and the monodisperse silver selenide nanocrystals provided by the invention is suitable for large-scale industrial production and has quite broad market prospect.

The invention belongs to the technical fields of medicaments and organic synthetic intermediates and in particular relates to a method for synthesizing 4-aryl-1H-1,2,3-triazole by using 1,1-dibromo-1-olefin. A 4-aryl-1,2,3-triazole compound is synthesized by using a sodium azide or organic nitrine compound and cheap and readily-available 1,1-dibromo-1-olefin as raw materials in the presence of alkali in dimethylsulfoxide through copper catalysis conveniently. The compound comprises a 1,2,3-triazole structure unit with bioactivity and can be used for synthesizing and modifying the organic synthetic intermediates and the medicaments. A novel and effective synthetic method is provided for medicament screening.

The invention provides a method for preparing a synthesized cobalt-gold double-metal alloy nano particle and belongs to the technical field of inorganic material preparation processes. The method comprises the following steps of: 1, adding polyvinylpyrrolidone and inorganic salt of cobalt into an ethylene glycol solvent to obtain mixed solution; 2, under the condition of stirring, adding hydrazine hydrate and ethylene glycol solution of chloroauric acid into the mixed solution sequentially; and 3, removing a heating source after the reaction is stopped, performing centrifugal separation, collection and deposition, washing by using ethanol and drying. The cobalt-gold double-metal alloy nano particle prepared by using the method for preparing the synthesized cobalt-gold double-metal alloy nano particle has the characteristic of a chain structure. In the method, inorganic substances are used as raw materials, so the reaction is low in toxicity and the raw materials are more economical; the cobalt and the gold of the product are distributed uniformly, and a proportion of the cobalt to the gold can be regulated within a certain range; moreover, the reaction time is short, the process is simple and the production can be enlarged easily.

The invention discloses a lithium ion battery silicon oxygen anode material and a preparation method thereof, and a lithium ion battery. The lithium ion battery silicon oxygen anode material is a core-shell structure, the core-shell structure is composed of an inner core and a coating layer, the inner core is a mixture of silicon oxide and element doped graphite, and the coating layer is organic pyrolytic carbon, wherein, the element is at least one of H, S, P, Cu, Fe and Ni. The anode material is high in first coulombic efficiency and long in service life, and has the high rate performance.

The invention relates to layered perovskite red phosphor for a white LED and a preparation method thereof. The structural formula of the layered perovskite red phosphor is (A1-xMexBx) 4Ti3O10, wherein A is Ca or Sr, Me is rare earth element Eu or rare earth element Pr, B is Li or Na or K, and x is larger than or equal to 0.005 and smaller than or equal to 0.1. The layered perovskite red phosphor is prepared through a solid phase method. The excitation spectrum of the layered perovskite red phosphor ranges from 350 nm to 400 nm, and the layered perovskite red phosphor can be applied to the white LED and other luminescent material fields; the emission wavelength of the layered perovskite red phosphor is in the red light range of 590 nm to 650 nm, the emission intensity is high, and the color purity and the color rending index are high; raw materials are economical, the technology is simple and controllable, an experimental production period is short, and the layered perovskite red phosphor is high in stability.

The invention provides a fluorescence probe for identifying cupric ions under an alkaline condition and a preparation method and application of the fluorescence probe, and mainly solves the problem that an existing fluorescence probe cannot quantificationally detect the cupric ions under a strongly basic condition while serving as a basic indicator. The fluorescence probe is a covalent combinationof 2-(2-hydroxyphenyl)benzothiazole and salicylhydrazide. The method comprises the steps that 1, 3-methylsalicylaldehyde and o-aminobenzenethiol react to obtain a compound 1; 2, the compound 1 obtained in step 1 reacts with urotropine to obtain a compound 2; 3, the compound 2 obtained in step 2 reacts with the salicylhydrazide to obtain a target compound Z. The fluorescence probe is used for thesensing detection of the content of the cupric ions under the strongly basic condition, and is used for the detection of pH values as a weakly basic indicator. The invention belongs to the field of fluorescence probes.

The invention discloses a preparation method of a zeolite imidazole framework structure material. According to the method, a zeolite imidazole framework structure is subjected to ion exchange to become a composite of two metal ions, wherein post-exchanged particles have a nuclear magnetic resonance effect. The method is mild in reaction condition, easy to operate and low in raw material cost and comprises simple steps. The zeolite imidazole framework structure contrast medium prepared with the method has good water solubility, improved application safety, small toxicity to normal cells and efficient contrast effects.

The invention discloses amphipathic asymmetric double-ion perylene bisimide dye, a preparation method thereof and application thereof in a living cell membrane mark fluorescence imaging aspect and belongs to the technical field of biomarker. According to the preparation method, sea island position chlorine or bromine-substitution perylene tetracarboxylic dicarboxylic anhydride or sea island position unmodified perylene tetracarboxylic dianhydride is utilized as fluorophore, and a hydrophobic alkyl chain and a hydrophilic double-ion radical are respectively led into two ends to obtain the amphipathic asymmetric double-ion perylene bisimide dye. By means of leading into the double-ion radical, water solubility and biocompatibility of a whole structure are improved, and cellular poison of the whole structure is reduced. The dye can be applied to external and internal cell membrane mark fluorescence imaging. As perylene with good photochemical stability and near-infrared emission wavelength is utilized as the fluorophore, effective marking time is greatly improved in a biological living cell membrane imaging process through an electrostatic force effect between a double-ion structure and a membrane structure, and time duration can be 72 hours or more.

The invention prepares B4C hard alloy material by mechanochemical method, including the techniques of proportioning components, processing by milling jar and preparing, and its characteristic: the portions of components of raw material: B2O3 60-92%, graphite 8-40% and the weight ratio of assistant Mg to B2O3 is 0-1.1; the raw material B2O3, C and assistant Mg are particles with the maximum size all less than 3 mm; the milling jar body and the milling jar cover are connected by a thread and there is a multiporous medium pad with average aperture 50-100 mum added in between; the pressure in the milling jar is provided by the thread and the pad; the preparing technique has the steps: preparing material; placing in the milling jar; fixing the milling jar; starting up machine; regulating working conditions to make the acceleration of particles 25-80 times as large as gravity; stopping machine; pickling and then washing with water. Its advantages are: simple processing course; uniform components; high purity.

The invention discloses a novel synthesis process of prasugrel. The novel synthesis process comprises the steps: firstly, carrying out benzyl protection by taking 4, 5, 6, 7-tetrahydrothieno[3, 2-c]pyridine, benzaldehyde and sodium triacetoxyborohydride as starting raw materials to generate 5-benzyl-4, 5, 6, 7-tetrahydrothieno[3, 2-c]pyridine; then, brominating the 5-benzyl-4, 5, 6, 7-tetrahydrothieno[3, 2-c]pyridine by using hydrobromic acid to obtain 2-bromo-5-benzyl-4, 5, 6, 7-tetrahydrothieno[3, 2-c]pyridine; next, catalytically synthesizing 2-acetoxy-5-benzyl-4, 5, 6, 7-tetrahydrothieno[3, 2-c]pyridine by taking palladium acetate as a catalyst and XPhos as a ligand; and finally, carrying out hydrodebenzylation, and coupling the product with alpha-bromo-o-fluorobenzyl cyclopropyl ketone to obtain a target molecule 2-acetoxy-5-(alpha-cyclopropylcarbonyl-2-fluorobenzyl)-4, 5, 6, 7-tetrahydrothieno[3, 2-c]pyridine hydrochloride, i.e., the prasugrel hydrochloride. The process is simple, convenient and novel in route, easy to obtain raw materials, mild in condition, convenient to operate, high in total yield up to 80-90% and suitable for large-scale production.

The invention relates to the field of lithium batteries, and discloses a boron doped modified soft carbon coating negative electrode material with high stability under a high-low temperature environment and a preparation method thereof. An amorphous carbon-carbon lay is formed on that surface of a negative electrode substrate aft carbonization by a soft carbon source, boron oxide is generated by decomposing a boron compound at a high temperature, the reaction of the boron oxide with the amorphous carbon and the surface of the negative electrode substrate is controlled, and a composite structure such as a boron-carbon bond and a boron-carbon-oxygen bond is for on the surface of the negative electrode material at a high temperature. 1, that soft carbon coat can reduce the impedance of the material under the low temperature, improve the liquid absorption performance, increase the low-temperature discharge voltage platform and greatly improve the low-temperature performance of the material; 2. By the catalysis of boron, the degree of graphitization of the cathode material is increased by reducing the surface defects, so that the specific surface area is greatly reduced, and the side reaction of the cathode material with the electrolyte at high temperature is reduced by the smaller specific surface area, and the performance at high temperature is obviously improved.

The invention discloses a synthesis method of aromatic borate compounds, belonging to the technical field of chemical synthesis of intermediates. The method particularly comprises the following steps: (1) adding acetonitrile, aryl sulfonyl chloride, pinacone biborate and dipotassium hydrogen phosphate into a reaction tube, tightening the plug of the reaction tube, and carrying out reaction at room temperature in the reaction tube under the irradiation of an ultraviolet lamp for 24 hours while magnetically stirring; and (2) after the reaction finishes, evaporating under reduced pressure to remove most of the solvent, carrying out separation purification on the residual mixed solution by column chromatography by using an eluent composed of petroleum ether and ethyl acetate in a volume ratio of 10:1-30:1, thereby obtaining the product. The method has wide applicability in the fields of organic synthesis, materials, medicine, pesticides and the like. The method has the advantages of low cost, high yield and the like, is simple to operate, and thus, has favorable application prospects.

The invention relates to the field of lithium batteries, and discloses a boron-doped negative electrode material with good high temperature performance and a solid-phase preparation method thereof. Asa boron oxide compound is used as a dopant, the boron oxide compound is decomposed to generate boron oxide at high temperature directly through a solid-phase reaction, and the boron oxide is controlled to react with the surface of the negative electrode material. The structure of the material of the invention is characterized in that the composite structure of a boron-carbon bond and boron-carbon-oxygen bond and the like is formed on the surface of the negative electrode material from the original defect state. By surface modification, on the one hand, On the other hand, the surface defects of the negative electrode material can be reduced by the composite reaction of boron oxide and the surface of the negative electrode material, so that the specific surface area of the negative electrode material can be greatly reduced, and the side reaction of the negative electrode material with the electrolyte at high temperature can be reduced by the smaller specific surface area, and the high temperature performance can be obviously improved.

The invention relates to the technical field of lithium ion battery negative electrode materials. The invention provides a carbon nanomaterial / amorphous carbon / silicon monoxide composite material anda preparation method thereof in order to solve the problem that silicon-oxygen particles lose electrochemical activity due to the fact that an existing silicon monoxide-based composite material is extremely likely to break away from contact after being charged and discharged. The carbon nanomaterial / amorphous carbon / silicon monoxide composite material is prepared from the following components in parts by weight: 75-97 parts of silicon monoxide, 1-50 parts of a carbon source, 0.1-3 parts of a thickening agent and 0.1-5 parts of a carbon nanomaterial. According to the composite material, the surface layer of silicon monoxide particles is coated with a layer of amorphous carbon; meanwhile, the carbon nanomaterial is uniformly loaded on the surfaces of the silicon monoxide particles, and due to the limiting effect of the amorphous carbon coating layer and the conductive effect of the carbon nanomaterial, the problem of structural pulverization failure of the material in the charging and discharging process can be greatly solved, and good electrochemical performance is shown.

The invention relates to an alternative multilayer graphene-rodlike ferric oxide composite material and a hydrothermal synthesis method thereof. The preparation method comprises that sodium acetate micromolecules are taken as a structure directing agent, ferric oxide is controlled to be grown into a nanorod structure on the surface of graphene and be self-stacked under hydrothermal condition, so that the alternative multilayer graphene-rodlike ferric oxide composite material is formed. The prepared material is structurally characterized in that rodlike ferric oxide and graphene are in an alternative multilayer state, and the rodlike ferric oxide is uniformly loaded on the two surfaces of a graphene sheet layer; restriction and electrical conductivity of a graphene nanosheet can greatly alleviate the problem of structure efflorescence of the material in charging and discharging processes, and good electrochemical properties are shown; and the alternative multilayer graphene-rodlike ferric oxide composite material has the advantages of simple preparation technology, unique structural design, high specific capacity and good cycle performance.

The invention discloses a synthetic method for 2-methyl-3-trifluoromethylaniline. The method comprises the following steps: with 2-chloro-3-trifluoromethylaniline as a raw material, introducing a methylthio group onto the 2-chloro-3-trifluoromethylaniline, carrying out a reaction with sulfonyl chloride so as to convert the methylthio group into a chloromethyl group, and carrying out neutralizationand hydrogenation so as to obtain a pure product namely the 2-methyl-3-trifluoromethylaniline. The synthetic method provided by the invention has a synthetic route which is described in the specification. The preparation method provided by the invention adopts more economical raw materials, has simple and convenient preparation process, is free of participation of toxic substances, reaches a yield of 70%, obtains a product with a purity higher than 99%, has good economic significance, and is applicable to large-scale industrial production.

The invention discloses an organelle targeting photosensitizer capable of activating pyroptosis of tumor cells and a preparation method and application thereof. The Mito-ZS photosensitizer is a mitochondrial targeting photosensitizer; the Lyso-ZS photosensitizer is a lysosome targeting photosensitizer; the ER-ZS photosensitizer is an endoplasmic reticulum targeting photosensitizer. The photosensitizer activates a pyroptosis pathway by performing precise targeting therapy on organelles in tumor cells so that photodynamic therapy and immunotherapy strategies are perfectly combined, and the photosensitizer has a wide application prospect in the field of cancer therapy.

The invention discloses a synthetic method of (-)-Corey lactone diol. According to the synthetic method, the target product is prepared from dicyclopentadiene as a raw material by depolymerization, cyclization, oxidation, dechlorination, ring opening, resolution, Prins reaction and hydrolysis reaction. The disclosed synthetic route adopts economical raw material and is high in resolution efficiency and suitable for industrial production.

The invention belongs to the technical field of molecular sieves and particularly relates to a cubic or sheet-shaped nano SAPO-34 molecular sieve and application thereof in conversion, separation and absorption of all kinds of hydrocarbons. The dimension range of the molecular sieve is within 20-300nm and is rapidly prepared by using tetraethyl ammonium hydroxide as template agent, mixing the tetraethyl ammonium hydroxide with an aluminum source, a silicon source and a phosphorus source and adding specific solvent to control gel concentration through the traditional hydrothermal or microwave heating method. The nano-scale SAPO-34 molecular sieve synthesized by adopting the method has the characteristics that the cost of raw materials for gel is low, the production speed of the molecular sieve is rapid, the preparation time of crystallized start materials is short, the reaction energy consumption is low, the yield of the molecular sieve is high, the catalytic application life is long and the catalytic effect of the molecular sieve in catalytic reaction can be obviously improved.

The invention discloses a preparation method of lenalidomide. The preparation method comprises the following specific steps: taking 2-methyl-3-nitrobenzoic acid as a raw material to prepare methyl 2-bromomethyl-3-nitrobenzoate; taking L-glutamic acid as a raw material to prepare N-CBZ-L-glutamic acid; taking N-CBZ-L-glutamic acid as a raw material to prepare 3-amino-2,6-piperidinone hydrochloride;taking methyl 2-methyl-3-nitrobenzoate and 3-amino-2,6-piperidinone hydrochloride as raw materials to prepare 3-(4-nitro-1,3 dihydro-1-oxo-2-hydrogen-isoindole-2-yl) piperidine-2,6-dione; taking the3-(4-nitro-1,3 dihydro-1-oxo-2-hydrogen-isoindole-2-yl) piperidine-2,6-dione as a raw material to prepare the lenalidomide. The preparation method has the advantages of being simple in process, economic in raw materials, less in byproduct, simple to purify, higher in yield, environment-friendly and the like, is simple in post-treatment, has better practicality and application value and also has great industrialization prospect.

The invention discloses a synthesis method for a 3-(trifluoroacetyl)indole derivative and belongs to the technical field of organic synthesis intermediates. The method particularly includes the following steps: 1) feeding dimethyl sulfoxide, an indole derivative, ethyl trifluoropyruvate and cuprous chloride into a pressure-resistant reaction tube, tightly screwing a plug of the reaction tube, and performing a magnetic-stirring reaction for 12 h in oil bath at 80 DEG C; 2) when the reaction is finished, performing extraction with ethyl ether and mixing organic phases, performing pressure reduced evaporation to remove most of the solvent, and performing column chromatography separation and purification to residual mixture liquid with petroleum ether and ethyl acetate, volume ratio being 5:1-10:1, as a leaching liquid, thereby producing the product. The 3-(trifluoroacetyl)indole derivative has wide applications in the fields such as medicines, pesticides, etc. The synthesis method is low in cost, has simple operations and high yield, and has excellent application prospect.

The invention discloses a preparation method of pyrochlore type rare-earth titanate powder. The preparation method adopts a soft chemical sol-gel method to prepare and comprises the following specificsteps: (1) weighing rare-earth nitrate powder and alcoholate of titanium respectively according to a stoichiometric ratio; (2) dissolving the rare-earth nitrate raw material into absolute ethyl alcohol at room temperature to obtain a solution A; adding acetylacetone and the alcoholate of titanium into the absolute ethyl alcohol at the same time to obtain a solution B; mixing the solution A and the solution B to obtain transparent sol; dropwise adding a diluted nitric acid solution into the transparent sol under the condition that the temperature is 40 to 60 DEG C and continuously stirring; monitoring the pH (Potential of Hydrogen) value; stopping dropwise adding until the pH value is 4.0 to 5.0; standing for 15 to 30min to obtain transparent wet gel; (3) drying the wet gel for 12 to 24h under the condition that the temperature is 100 to 120 DEG C; grinding to obtain powder; (4) putting the powder into a muffle furnace; keeping heat for 2 to 4h under the condition that the temperatureis 750 to 850 DEG C, so as to obtain the pyrochlore type rare-earth titanate powder. The preparation method disclosed by the invention has the advantages of simple preparation technology and low energy consumption; the prepared powder has uniform chemical composition and high product purity.

The invention discloses a method for preparing a DLC (Diamond-Like Carbon) coating with high visible light transmissivity. The coating is used for protecting an optical device working in the visible light waveband, and the method comprises the ion cleaning technology and sputtering coating technology. In the two technological processes, the temperature of a vacuum room is always maintained between 200 DEG C and 400 DEG C. The invention has the main advantages that the coating method adopts the PVD film coating technology and has the advantages of simple preparation technology, economic raw materials, no pollution, nontoxic tail gas generated by reaction and the like, and the coating has high transmissivity to visible light with waveband from 600 to 800 nm, high hardness, strong scratch resistance and stable physical and chemical properties.

The invention relates to a waterproof bonding agent for ignition powder and a preparation method of the waterproof bonding agent, and belongs to the field of energy containing and chemical engineering inter-disciplines. The waterproof bonding agent comprises the following components: 80-90% of starch, 2-8% of ethyl cellulose, 3-6% of one or more pre-polymers, 2-5% of one or two curing agents and 1.5-2.5% of a waterproof agent. The prepared waterproof bonding agent, namely an adhesive, is rich in raw materials, economical, non-toxic, harmless, and free of volatility and free formaldehyde release, thereby being an environment-friendly adhesive; meanwhile, the waterproof bonding agent is relatively high in bonding property, strength and water resistance; the energy containing pre-polymers are adopted for the waterproof bonding agent, so that the energy of the waterproof bonding agent can be improved, and then the ignitability of the ignition powder can be effectively improved.

The invention discloses a manganese-doped metal sulfide red fluorescent powder and a preparation method thereof. The chemical formula of MnxM[7-x]In28S52(SH)4.[H<+>-DBN]8.[H<+>-PR]4, wherein M is Cd<2+> or Zn<2+>, DNB is 1,8-diazadicycloundecylenic-7-ene, and the molecular formula is C7H12N2; PR is piperidine of which the molecular formula is C5H11N; and x is the doping amount of manganese, and 0< x<=7. The manganese-doped metal sulfide red fluorescent powder is prepared by a solvothermal process. Under the excitation of 350-550nm light, the fluorescent powder can emit red fluorescence of which the central wavelength is 610-650nm, and the fluorescent powder has high luminescent intensity. Compared with the traditional red fluorescent powder synthesis process, the preparation method disclosed by the invention has the advantages of simple equipment, mild reaction conditions, high preparation speed and economical raw materials; the reaction temperature does not need to achieve 1000 DEG C; and the method does not use any rare earth ion, does not need any shielding gas during reaction, and thus, is suitable for industrial production.