The invention discloses a high-salt industrial wastewater treatment process system. The system includes a raw water equalizing pool, a mechanical accelerated clarification pool, a clear water pool, a multi-medium filter, a weak acid cation bed, a softened water pool, a self-cleaning filter, an ultrafilter, an ultrafilted water pool, a primary RO security filter, a primary RO instrument, a concentrated water pool, a secondary RO security filter, a secondary RO instrument, a tertiary RO instrument, a pre-desalted water tank, a lime device, a FeCl3 device, a PAM device, a MgO device, a soda ash device, a HCl device, a NaOH device, a scale inhibitor device and a reducing agent device; and the process system also comprises, related supporting, a cleaning system, an adding medicine storage system, a compressed air system, a wastewater neutralization system, an electrical system and an instrument control system in order to ensure the long-term stable operation of the process system. The high-salt industrial wastewater treatment process system has the advantages of operation at a high pH value all the time, effective avoiding of the pollution plugging of the RO instrument, and realization of investment and operation cost saving by utilizing the regeneration characteristic of weak acid cation resin.