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1 results about "Cryphonectric acid" patented technology

Polyampholyte cell cryoprotectants, methods of making and polyampholyte cell cryopreservation solutions

The application provides a polyamphoteric electrolyte cell cryoprotective agent and a preparation method and application of a polyamphoteric electrolyte cell cryopreservation solution, relates to the fields of biomedical materials technology and cell cryopreservation, and aims to solve the problems of low cell recovery rate and short low-temperature storage time of cells in the existing cell cryopreservation technology. The polyamphoteric electrolyte cell cryoprotective agent comprises polylysine, polyacrylic acid and graphene oxide connected through a chemical bond, the mass ratio of the polyacrylic acid and the polylysine is 10:1-2:1, and the mass ratio of the total mass of the polyacrylic acid and the polylysine to the mass of the graphene oxide is 1:2-10:1. The polyamphoteric electrolyte cell cryoprotective agent can not only reduce the osmotic damage of cells in the freezing and thawing process by adjusting the osmotic pressure, but also improve the freezing efficiency and inhibit the formation and growth of ice crystals. The protective agent can be used in the fields of stem cell cryopreservation, immune cell cryopreservation and the like due to the excellent cell protection performance and good stability.
Owner:SUZHOU UNIV