10 results about "Fe3o4 magnetic nanoparticles" patented technology

The present application belongs to the technical field of biological medicine, and particularly relates to a thiol phenylboronic acid mediated nano-enzyme immunochromatography reagent and application thereof. The present application utilizes the broad-spectrum binding ability of MPBA to the glycosylated molecules on the surface of pathogens, and combines the colorimetric catalytic double enhancement effect of the virus-like biomimetic magnetic nano-enzyme (FeAu@AuIr), to improve the detection sensitivity. The probe takes Fe3O4 magnetic nanoparticles as the core, and sequentially loads large-diameter gold nanoparticles (Au) and gold-iridium alloy (AuIr) with high catalytic activity, to enhance the pathogen capture capacity and signal amplification effect. Combined with the antibody modified immunochromatography strip, Streptococcus pneumoniae, Pseudomonas aeruginosa and SARS-CoV-2 can be simultaneously detected, and the detection sensitivity is greatly improved. Through verification of 170 clinical samples, the present application has good application prospect in on-site rapid detection, and provides an efficient and low-cost solution for precise screening of respiratory tract infectious pathogens.

This invention relates to a self-triggered demulsification Pickering emulsion cascade catalytic system, its preparation method, and its application. The preparation method includes: preparing Fe3O4 magnetic nanoparticles by co-precipitation; coating their surface with a SiO2 shell using a modified Stöber method to obtain Fe3O4@SiO2 core-shell nanoparticles; simultaneously grafting a triamine silane coupling agent and octyltrimethoxysilane onto the Fe3O4@SiO2 surface using a one-pot method to obtain magnetic amphiphilic nanoparticles; dividing the magnetic amphiphilic nanoparticles into two batches, and immobilizing glucose oxidase and Candida antarcticis lipase B respectively via EDC / NHS-mediated amide coupling reaction to obtain nanoparticle catalysts; using the nanoparticle catalysts as solid emulsifiers in Pickering emulsions to construct an oil-water two-phase cascade catalytic system, realizing a cascade catalytic reaction of glucose oxidation – peracidification – olefin epoxidation; utilizing the accumulation of gluconic acid during the reaction to lower the pH, triggering emulsion demulsification, achieving product separation and magnetic recovery of the nanoparticle catalysts.

The application discloses a kind of magnetic nanocomposite and its application in dye wastewater treatment, belong to water treatment functional material technical field.The magnetic nanocomposite with Fe3O4 Magnetic Nanoparticle as core, successively coats silica layer, graphene nanosheet layer and chitosan crosslinking layer, through the synergistic effect of chitosan liquid ultrasonic modification and graphene nanosheet surface modification, realize efficient adsorption and magnetic separation recovery to dye molecule.The preparation process of the application is mild controllable, environment-friendly, cost moderate, has wide application prospect in printing and dyeing wastewater advanced treatment, industrial dye pollution control field, graphene nanosheet greatly promotes specific surface area and adsorption site, chitosan provides a large number of amino / hydroxyl active groups, three synergies realize high adsorption capacity.Graphene nanosheet is reduced by liquid phase ultrasonic stripping, avoids stacking;Chitosan is modified by ultrasonic and TiO2 is scattered, combination is more firm, material structure is stable, not easy to lose, acid and alkali resistant.

The present application relates to the technical field of nanocapsules for medical preparations, and particularly relates to dTRIM24 biocompatibility-based anti-atherosclerotic nanoparticles composed of nanoparticles and M1 macrophage membrane vesicles. By using a microfluidic photoporation chip, the nanoparticles are encapsulated by the M1 macrophage membrane vesicles. The nanoparticles are obtained by combining dTRIM24 and Fe3O4 magnetic nanoparticles. The biomimetic nanoparticles of the present application reasonably solve the problems of poor specificity and low efficiency, and have improved anti-atherosclerotic plaque-targeting and biological homology.

The invention discloses a treatment method of paint-containing high-COD (Chemical Oxygen Demand) waste liquid in the automobile manufacturing industry, and belongs to the technical field of automobile manufacturing wastewater treatment. The method comprises the following steps: firstly, loading Fe < 2 + > and Cu < 2 + > through Fe3O4 magnetic nanoparticles, and coating with a KH-550 ethanol solution to form a siloxane layer, so as to prepare a bimetallic magnetic Fenton reagent; the reagent is added into the waste liquid, the pH is adjusted to 2.5-4.5 with an H2SO4 solution, and then ozone is introduced for pre-oxidation; then adding rare earth doped amphoteric ZIF-8, adjusting the pH value to 6.5-8.5 by using an alkaline solution, stirring to form a composite floc, and standing; and recovering flocs through magnetic separation, collecting supernate, crushing residual flocs through ultrasonic treatment, and then introducing the crushed flocs into a gradient aperture ceramic membrane assembly loaded with a MnO2-gamma-FeOOH gradient catalyst layer for filtration. Through the steps of bi-metal synergistic catalysis enhanced oxidation, ZIF-8 adsorption and the like, efficient removal of refractory pollutants is achieved, the sludge yield is greatly reduced, membrane operation is stable, a core material can be recycled, and the method is suitable for deep treatment of paint-containing high-COD waste liquid in the automobile manufacturing spraying process.

The application relates to a preparation process of an antibacterial magnetic health-care fabric. The preparation process of the antibacterial magnetic health-care fabric comprises the following steps: Fe3O4 magnetic nanoparticle preparation; Fe3O4@SiO2@Ag magnetic nanoparticle preparation; magnetic fiber preparation: ultrasonic dispersion of the magnetic particles in bamboo fibers for a certain time, spraying of the spinning solution out of a spinning hole by using a wet spinning machine, direct entering of the spinning solution into a prepared coagulation bath to react and form a fiber bundle, and then fiber bundle stretching and winding by using front and rear stretching rollers. The main process of the spinning process is: beating - carding - drawing - roving - spinning - bobbin winding - doubling - doubling twisting. The magnetic fiber and the negative ion viscose fiber are used to develop single-layer and double-layer fabrics based on 2 / 2 twill as a basic structure, and the warp and weft yarns of each fabric are the same. The application has the advantages of green health, antibacterial, health care and the like.

The invention discloses photoaffinity magnetic nano-microspheres specifically enriched with bile acid acting targets as well as a construction method and application of the photoaffinity magnetic nano-microspheres. The microsphere is sequentially composed of Fe3O4 magnetic nanoparticles, a TAD photoaffinity link layer and a bile acid molecular layer from inside to outside, and is called BAs microsphere for short. Bile acid molecules are fixed on the surfaces of the BAs microspheres through a photoactivation coupling technology to serve as molecular bait, potential targets in a biological sample are captured by the bile acid molecules fixed on the surfaces of the microspheres on the basis of specific interaction characteristics, and different targets are enriched on the surfaces of solid-phase microspheres. The preparation method comprises the following steps: firstly, preparing a target spot, stripping the target spot from the surface of the microsphere through specific elution, and accurately identifying and analyzing by adopting a high-resolution mass spectrum, so as to obtain a direct acting target spot of a specific bile acid component, and further explaining the pharmacological mechanism of bile acid from the source of the target spot.

The invention discloses a preparation process of a magnetic bean dreg-based nitrogen-doped carbon-titanium dioxide ternary composite water purification filter element, and belongs to the technical field of environmental functional materials and water treatment. The process comprises the following steps: washing and drying agricultural waste bean dregs serving as a raw material, mixing with a nitrogen-containing precursor, and performing segmented high-temperature carbonization to prepare nitrogen-doped bean dreg carbon (N-BC) with high specific surface area; further performing in-situ growth of FeOmagnetic nanoparticles on the N-BC through a solvothermal method to obtain a magnetic carrier M-N-BC; and loading TiO nanoparticles on the surface of the M-N-BC by a sol-gel method, and calcining to obtain the M-N-BC / TiO ternary composite photocatalytic material. And finally, mixing the obtained material with a binder and a pore forming agent, and forming and sintering to prepare the multi-layer structure filter element. According to the prepared filter element, pollutants are enriched by utilizing high adsorbability of a carbon material, the pollutants are degraded by utilizing photocatalytic activity of TiO, and material recovery is realized by utilizing magnetism of FeO.

This invention discloses a graphene aerogel surface microwave absorbing material supported on Fe / N co-doped hollow carbon nanospheres and its preparation method. First, a reduced graphene oxide aerogel is prepared using graphene oxide as a raw material. Then, hollow Fe3O4 magnetic nanoparticles are prepared via a hydrothermal method using FeCl3·6H2O and ammonium acetate as raw materials. Finally, Fe3O4 / PPy / reduced graphene oxide aerogel is prepared by in-situ polymerization, and the graphene aerogel supported on Fe / N co-doped hollow carbon nanospheres is obtained through high-temperature heat treatment. The graphene aerogel surface microwave absorbing material supported on Fe / N co-doped hollow carbon nanospheres of this invention exhibits excellent dielectric and magnetic losses. Simultaneously, the magnetic Fe nanoparticles in the material can effectively convert electromagnetic wave energy, achieving excellent microwave absorption performance, and showing great potential in next-generation cutting-edge advanced nanocomposite materials.

This invention belongs to the field of environmental functional materials and wastewater treatment technology, and discloses an aminopolycarboxylic acid modified chitosan-sodium alginate composite magnetic gel sphere, its preparation method, and its application. Method: Chitosan, an aminopolycarboxylic acid compound, and water are mixed and stirred until homogeneous. The pH is adjusted to 5-6 with alkali to obtain a mixed solution. This solution is then mixed, stirred, and reacted with an aqueous solution of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide under ice-water bath conditions to obtain aminopolycarboxylic acid modified chitosan. This chitosan is then mixed with Fe3O4 magnetic nanoparticles and an aqueous solution of sodium alginate to obtain a suspension. This suspension is then added dropwise to a mixture of calcium chloride and polyacrylic acid to carry out a cross-linking and solidification reaction. After washing with water and magnetic separation, aminopolycarboxylic acid modified chitosan-sodium alginate composite magnetic gel spheres are obtained. The gel spheres of this invention not only have a large adsorption capacity and good selectivity, but also have a stable mechanical structure, are easy to separate and recover, and have good reusability.