6results about How to "Accelerates the infiltration process" patented technology

The invention relates to the field of paint spraying, in particular to a curved surface paint spraying boundary technology which comprises the following steps that S1, a first color layer is sprayed to a curved surface structure; s2, removing the first color layer on the second side of the color block boundary; s3, spraying a release interlayer on the curved surface structure, wherein the release interlayer is sprayed on the second side of the color block boundary and the surface of the first color layer; s4, removing the release interlayer on the second side of the color block boundary; s5, spraying a second color layer on the curved surface structure, wherein the second color layer is sprayed on the second side of the color block boundary and the surface of the release interlayer; and S6, removing the release interlayer so as to remove the second color layer sprayed on the surface of the release interlayer, and respectively forming a first color block and a second color block on the first side and the second side of the color block boundary. The multi-color paint spraying device has the effect of conveniently carrying out boundary multi-color paint spraying on the curved surface structure.

The present application relates to the technical field of biological medicine, in particular to a kind of nano-molecular probe with targeting and its preparation method and application.The plasmid of immune checkpoint corresponding receptor of stable expression tumor surface negative regulation molecule is synthesized in the present application, which is prepared into targeted nano-molecular probe with cell membrane nanocapsule of enhancing T cell activity ligand and being marked with fluorescence, and melanin nanosphere of simultaneously loading therapeutic drug.The targeted nano-molecular probe provided in the present application can be long-circulated in vivo, reduce the dosage and administration frequency of chemotherapeutic drug.It also has the advantages of improving the drug resistance of tumor site to therapeutic drug, targeting tumor DNA damage and significantly enhancing the infiltration and activation of immune cells in tumor site.

The application discloses a preparation method of hydroxyl nano-aluminum oxide with controllable hydroxyl content, and relates to the technical field of inorganic functional material preparation. The method comprises the following steps: performing online gasification purification of an organic aluminum precursor in a closed integrated reaction system; guiding the online gasification purified organic aluminum precursor into a hydrolysis-hydrothermal crystallization reaction zone through a gas phase transportation channel, performing a controlled hydrolysis reaction, and generating amorphous aluminum hydroxide sol; sealing the hydrolysis-hydrothermal crystallization reaction zone, performing hydrothermal treatment on the amorphous aluminum hydroxide sol, and crystallizing the amorphous aluminum hydroxide into hydroxyl nano-aluminum oxide; and recovering and drying the hydroxyl nano-aluminum oxide. The application solves the fundamental contradiction between the improvement of material chemical purity and the maintenance of surface functional hydroxyl in the prior art, avoids the damage of traditional acid washing or calcination to the hydroxyl, and significantly improves the dispersibility, interface bonding force and electrolyte wettability of the material in the field of lithium ion batteries.

The application discloses a nitrogen-doped carbon lithium-sulfur battery positive electrode carrier material with directional pores and iron monatomic anchoring, and a preparation method and application thereof, and belongs to the technical field of lithium-sulfur battery positive electrode materials. Graphene oxide and cellulose nanofibers are dispersed in water to form a dispersion liquid; a mixed metal salt solution prepared by zinc salt and iron salt is added to the dispersion liquid, and a composite hydrogel is formed through electrostatic self-assembly; the composite hydrogel is placed on a pre-cooled metal substrate to perform directional freezing and freeze-drying, and an aerogel precursor with a directional pore structure is obtained; the aerogel precursor is subjected to programmed temperature carbonization with a solid nitrogen source, and a nitrogen-doped carbon lithium-sulfur battery positive electrode carrier material with directional pores and iron monatomic anchoring is obtained. Through the cooperation of directional freezing and gas-phase doping, vertical through pores are constructed, and iron monatomic atoms are anchored, the shuttle effect is inhibited, high specific capacity, excellent rate and long cycle life are realized, and the capacity retention rate reaches 88.5% after 600 cycles at 0.1C.

The application discloses a modified unsaturated polyester resin, raw materials of which comprise 1,2-propylene glycol 20-30 parts by mass, diethylene glycol 2-10 parts, ethylene terephthalate 15-30 parts, ethylene glycol 5-10 parts, phthalic anhydride 25-30 parts, maleic anhydride 2-8 parts, artificial stone aggregate 20-40 parts, amino-terminated polyamide amine 5-15 parts, activated calcium carbonate 100-200 parts, styrene 20-30 parts, catalyst 0.1-1 part, polymerization inhibitor 1-2 parts and antioxidant 2-5 parts. The application discloses a preparation method of the modified unsaturated polyester resin. The modified unsaturated polyester resin obtained by the application has good fluidity, can accommodate more calcium carbonate powder for infiltration, effectively reduces the cost of artificial stone products, has high bending strength and compression strength, and can meet the performance requirement of artificial stone.

The application discloses an aptamer-based functionalized nano linker, a preparation method and application, wherein the functionalized nano linker comprises a functionalized nano vesicle as a carrier, the functionalized nano vesicle is a biological nano membrane vesicle prepared through combination treatment of an ICD functionalized biological membrane and a biological membrane carrying an azido group; part of the azido groups of the biological nano membrane vesicle are loaded with an aptamer I for targeting DC cells through alkyne-azido cycloaddition reaction, and the other part of the azido groups are loaded with an aptamer II for targeting T cells through alkyne-azido cycloaddition reaction. The application designs a dual-specific functionalized nano linker, which can simultaneously target and link DC and T cells, the functionalized nano vesicle as the carrier itself has key proteins of ICD effect, can promote maturation of the dendritic cells and antigen cross-presentation, after linking with the T cells, can effectively activate the CD8+ T cells and differentiate the CD8+ T cells to cytotoxicity effect phenotype, and enhance killing of tumor cells.