The invention provides a nanoscale compound
antibacterial agent and a preparation method and application thereof, which relate to the technical field of antibacterial agents. The nanoscale compound
antibacterial agent is mainly prepared from nanosilver,
graphene,
protein,
phospholipid,
polysaccharide,
cholesterol,
vitamin and other raw materials, functional substances, such as the
vitamin, are wrapped by a lipidosome formed by the
protein, the
phospholipid, the
cholesterol and other materials, moreover, the nanosilver, the
graphene and other materials are loaded inside or on the surface of thelipidosome after being compounded, and thereby the nanoscale compound
antibacterial agent which is highly similar to a cellular structure is produced. The speed by which the compound antibacterial agent gets into microbial cells is high, and the compound antibacterial agent can gather around a focus to generate a high-concentration
drug effect; because the surface of the compound antibacterial agent is positively charged, the compound antibacterial agent can selectively adsorb, wrap, shield and kill
pathogenic bacteria and viruses, the surfaces of
pathogenic bacteria and viruses which are negatively charged, thus having a high
antibacterial effect. The invention further provides the preparation method of the nanoscale compound antibacterial agent, and the method can realize the uniform mixing of all the materials, thus being favorable for the increase of the stability of the nanoscale compound antibacterial agent.