An air cleaning device for a pharmaceutical workshop is disclosed. The air cleaning device comprises an air inlet device, a connecting device, a heating and disinfecting device, a pipeline device, a mixing device and an air outlet device. The air inlet device comprises an air inlet pipe, a first draught fan, an air inlet frame, a block, a first vertical bar, a first cross bar, a first rotating shaft, first bristles, a first filter screen and a first support. The connecting device comprises a first pipe, a second filter screen, a second vertical bar, a second cross bar and a second support. The heating and disinfecting device comprises a heating frame, a heat insulating plate, second fixing rings, a centralizing hopper, a heating bar, a thermal conductive plate, first fixing rings, a third filter screen, a fourth filter screen and a fifth filter screen. The pipeline device comprises a second pipeline, a first valve, a third vertical bar and a third cross bar. The mixing device comprises a mixing tank, a water inlet pipe, a water feeding hopper, a second valve, a second rotating shaft, second bristles, a sponge mat, a fifth filter screen and supporting bars. The air cleaning device can subject air in the pharmaceutical workshop to sufficient cleaning and disinfection, and can prevent pollution to the environment.