The invention discloses a
skin-sourced
streptococcus infantis CCSM002 capable of improving
skin health and a metagen of the
streptococcus infantis CCSM002, and belongs to the field of microbial technologies and medicines. The
streptococcus infantis CCSM002 provided by the invention has the capability of generating
oleamide, D-erythrodisphingosine and (2-oxo-2, 3-dihydro-1H-indole-3-yl)-
acetic acid, and the strain has a good effect of repairing a
barrier function in the aspect of external use and a good application prospect, specifically, the activity of damaged
HaCaT cells is improved
in vitro, the activity of the damaged
HaCaT cells is improved, the activity of the damaged
HaCaT cells is improved, and the activity of the damaged HaCaT cells is improved. The expression of tissue kininolase is reduced, and the
gene level expression of FLG, IVL, AQP3, ZO-1 and
Occludin can be improved at the same time in the aspect of improving
functional protein and
structural protein after damage. Therefore, the streptococcus infantis CCSM002 has a huge application prospect in preparation of external daily
chemical products or medicines for repairing the
skin barrier.