224results about How to "Fewer separation steps" patented technology

An integral catalyst TS-1 used for epoxidizing chloropropene to obtain epoxy chloropropane is prepared through calcining the multi-channel cylindrical porous ceramic in fuffle furnace, natural cooling, adding it to the synthetic liquid prepared from tert-butyl titanate, ethyl silicate, deionized water, ammonium tetrapropyl hydroxide and isopropanol, crystallizing reaction in crystallizer, and activating.

The invention relates to a novel technique for preparing long-chain alkane efficiently through a multifunctional catalyst in a one-step method. The novel technique can be used for producing the long-chain alkane in one step with high selectively under a relative mild condition, and solve the problems of strict reaction condition, low energy efficiency and low alkane selectivity in a process of preparing the long-chain alkane by biomass derivatives. According to the technique, condensation products (C8, C9, C13 and C15) of a biomass derivative, namely furfural or HMF (Hydroxy Methyl Furfural), and acetone are taken as the raw materials, and by designing the three-center multifunctional catalyst of metal (I)-metal (II)-acid, the original two steps of independent reactions which require strict reaction conditions and need different catalysts to join in are combined into an one-step reaction which requires tender reaction conditions, so that the selectivity on corresponding alkane (octane, nonane, tridecane and pentadecane) is improved greatly, the highest yield can be 97%, and meanwhile, a step of separating the product from the catalyst is omitted, therefore, the energy efficiency of the while process is improved by a great step.

The invention discloses a method for preparing a nuclear-shell-structured rutile monocrystal titanium dioxide nanowire array with a surface-cladding carbon layer, and the method is characterized by comprising the following steps: (a) immersing a rutile monocrystal titanium dioxide nanowire array into a phenol aqueous solution or an aqueous solution of phenol and a precious metal salt, preparing arutile monocrystal titanium dioxide nanowire array with a surface-cladding polyphenol compound by using a photochemical reaction method, then taking out the rutile monocrystal titanium dioxide nanowire array with the surface-cladding polyphenol compound, washing with water, and drying; and (b) carrying out high-temperature pyrolysis on the rutile monocrystal titanium dioxide nanowire array with the surface-cladding polyphenol compound in the presence of inert gas to obtain the nuclear-shell-structured rutile monocrystal titanium dioxide nanowire array with the surface-cladding carbon layer. By means of the preparation method disclosed by the invention, clean and pollution-free solar energy can be fully utilized so as to effectively reduce the energy consumption for production and the production cost. The prepared nuclear-shell-structured rutile monocrystal titanium dioxide nanowire array with the surface-cladding carbon layer not only has stable and efficient photocatalytic activity, but also can achieve wide-spectrum response to visible light so as to obviously improve the photo quantum yield of the titanium dioxide nanowire array and improve the solar utilization rate, and can be widely applied to the fields of hydrogen production through photodecomposition of water, pollutant degradation through photocatalysis and the like.

The invention provides a new method for synthesizing tapentadol hydrochloride and analogue of the tapentadol hydrochloride, and particularly provides a method for synthesizing a compound with the formula shown as a formula (1). Groups of the compound are defined in the specification. The invention also particularly provides a method for synthesizing the tapentadol hydrochloride and the analogue compound of the tapentadol hydrochloride by using 1-(3-substituted phenyl)-1-ketone compound as an initial raw material. According to the method, the raw materials are easy to obtain, and reaction conditions are mild; and the method is easy to control and operate, reduces production cost and is particularly suitable for industrial production.

The invention discloses a method for separating and extracting N-acetyl-D-glucosamine and D-glucosamine from ammonia sugar fermentation liquor. The method includes the steps of microfiltration, ultrafiltration, nanofiltration and the like, the fermentation liquor is filtered through a microfiltration membrane with the aperture of 0.1-10 micrometers to remove impurity particles and microbial thalli, protein, nucleic acid, colloidal particle large molecules and other impurities are removed through filtering by means of an ultrafiltration membrane with the aperture of 0.001-0.1 micrometer, and pigment, polypeptide, nucleotide and other small-molecular impurities are removed through a reverse osmosis system; N-acetyl-D-glucosamine is crystallized and separated from the fermentation filtrate containing N-acetyl-D-glucosamine and glucosamine. The method includes the steps of fermentation filtrate heating and concentration, seed crystal addition, temperature-control crystallization, N-acetyl-D-glucosamine crystal collection, residual glucosamine recycling and the like. The method is low in cost and does not influence the structure of N-acetyl-D-glucosamine, and the obtained N-acetyl-D-glucosamine is high in purity.

The invention relates to a rare-earth permanent magnet mixed with bayan obo co-existence and associated crude ores and a method for manufacturing the rare-earth permanent magnet. Compositions of the rare-earth permanent magnet are shown as a following formula of MM<x>Fe<y>A<z>B, the x is larger than or equal to 2 and is smaller than or equal to 2.5, the y is larger than or equal to 11 and is smaller than or equal to 14, the z is larger than or equal to 0 and is smaller than or equal to 0.6, the MM represents rare-earth mixed with the bayan obo co-existence and associated crude ores, and the A represents nanometer auxiliary alloy which includes one type of Nd elements, Pr elements, Al elements and Cu elements or a plurality of types of the Nd elements, the Pr elements, the Al elements and Cu elements. The rare-earth permanent magnet can be manufactured by the aid of a powder metallurgy technology and rapid quenching and thermal pressure and thermal deformation technologies. The rare-earth permanent magnet and the method have the advantages that the novel resource-saving rare-earth permanent magnet which is developed from the rare-earth mixed with the bayan obo co-existence and associated crude ores can replace the traditional rare-earth permanent magnet and is low in cost, and environmental pollution can be reduced; the magnetic energy product scope of the magnet ranges from 20MGOe to 40MGOe, and applicable scope gaps of ferrites and SmCo rare-earth permanent magnets can be effectively filled.

The invention belongs to the technical field of separation and purification of bio-active substances, more particularly relates to a method for directly separating and purifying the protamine from crude protamine extract with a reverse micelle method. The invention aims at solving the problems of complex process, multiple steps and long cycle of present protamine purification. The invention directly separates, purifies the protamine from the crude protamine extract by adopting the reverse micelle solution which consists of a surfactant and an organic solvent and can realize the high-efficient extraction and back extraction of the protamine by adjusting the conditions of extraction processes such as pH of water phases, ionic strength, phase ratio, contact time of two phases; the highest enzyme recovery rate can reach more than 96 percent and the purification factor reaches more than 2.1. The process has the effects of both concentration and decoloration. In addition, the separation and purification of the protamine with the reverse protamine technology have the advantages of short cycle, convenient continuous operation and being easily amplified.

The invention discloses an application of maca imidazole alkaloid, in particular to an application to the preparation of cardiovascular drugs. All or part of the components are prepared from one or mixture of compounds having the following chemical structural formula as shown in formula (I), wherein R1 can be H or CH3, and R2 is H or OCH3. The invention first discovers the remarkable pharmaceutical activity of the compounds on blood pressure drop and arrhythmia resistance. Therefore, the maca imidazole alkaloid prepared by the new process can be used for developing antineoplastic drugs and can be expected to act as drugs for treating corresponding cardiovascular diseases. Formula (I).

The invention discloses a method for separating and extracting L-arginine from fermentation liquor, which comprises the following steps: firstly, carrying out microfiltration on L-arginine fermentation liquor by a metal microfiltration membrane; and then, decoloring the obtained product; finally, sequentially carrying out reduced pressure evaporation, crystallization and refining on the decolored product. The method of the invention is simple and easy to operate, convenient in device maintenance and less in investment, and the adopted metal membrane is long in service time, has heat-resistance, acid-resistance, alkali-resistance and is easy to clean; the whole extraction process is performed by using a physical separation method, therefore, less acid, alkali and steam are consumed in the extraction process, and the extraction cost is greatly reduced; meanwhile, the method is mild in condition, is simple in operation, is few in separation steps, is less in waste water discharge, is high in yield, is good in product quality, and the like; and through analysis, the purity of the L-arginine product obtained through alcohol-precipitation and crystallization reaches over 99 percent.

An optimized karyote in-vitro separation kit comprises two reagents. The reagent 1 is composed of erythrocyte precipitant, sodium chloride or potassium chloride. The reagent 2 is composed of natrii diatrizoas and polysucrose No.400, natrii diatrizoas and polysucrose dextranum, or percoll, and has density of 1.076-1.090. An application method of the optimized karyote in-vitro separation kit includes directly adding 100ml of human marrow blood, umbilical cord blood or peripheral blood into 200ml of solution of the reagent 1, allowing for standing for 10-30 minutes, collecting supernate, centrifuging at 2000rpm (1100xg) for 5 minutes, discarding the supernate, adding remnant a centrifugal tube containing solution of the reagent 2, performing density gradient centrifugation for 30 minutes, controlling the rotation speed at 1500rpm, absorbing a karyote layer, performing centrifugal cleaning for once to three times, using 50ml of cell preservative solution for diluting, and taking 100 microliters for testing or self-testing.

The invention relates to a production method of Gamma-aminobutyric acid. The method comprises the following steps: (1) fermentation of monosodium glutamate isoelectric mother liquor: inoculating lactic acid bacteria strain to the monosodium glutamate mother liquor which is subjected to isoelectric crystallization, and fermenting to obtain the fermentation liquor of Gamma-aminobutyric acid; (2) removal of impurities: processing the fermentation liquor of the Gamma-aminobutyric acid through a ceramic membrane filter so as to remove larger particulate impurities and thallus, and concentrating, then adding dialysis water for dialyzing, so as to obtain the clear liquid of the ceramic membrane; (3) decolorizing and removing of micromolecular impurities: filtering the clear liquid of the ceramic membrane obtained in step (2) through a nanofiltration membrane, and then carrying out dialysis to obtain the clear liquid of the nanofiltration membrane; and (4) concentrating: concentrating the clear liquid subjected to the nanofiltration and dialyzing and obtained in step (3) through a reverse osmosis membrance, thus obtaining the concentrate of the reverse osmosis membrance, and finally drying to obtain the Gamma-aminobutyric acid. According to the method, the supernate obtained after the isoelectric extraction of glutamic acid in the monosodium glutamate production technology is recycled to produce the Gamma-aminobutyric acid; and the method is easy for industrial continuity, low in energy consumption, and high in purity of the Gamma-aminobutyric acid.

The invention relates to the technical field of solid-phase extraction-gas chromatography-mass spectrum coupling, and provides a test method for detection of tea polyphenol and flavonoid constituents of golden camellia. The test method comprises solid-phase extraction adsorption-gas chromatography-mass spectrum coupling detection, wherein the solid-phase extraction is carried out by a stirring rod in a direct stirring manner; the stirring rod is coated with a graphene-polymer coating on the basis of two-dimension or three-dimension; the materials of thegraphene-polymer coating comprise graphene and a graphene modified material; thegraphene modified material comprises graphene oxide, graphene-polyethylene glycol dimethyl acrylic ester, graphene-polypyrrole, graphene-polymethyl trimethoxy silane and a graphene nanomaterial. The test method for detection of tea polyphenol and flavonoid constituents of golden camellia has the characteristics of correct detection, high sensitivity, good preferential adsorption effect and long service life.

The invention provides a hierarchical pore SAPO-34 molecular sieve synthesis method which is characterized in that an aluminum source, a silicon source, a phosphorus source, an organic template agentand water are mixed and added into a hydrothermal reactor, and in-situ synthesis is performed to form an SAPO-34 molecular sieve with hierarchical pores. According to the hierarchical pore SAPO-34 molecular sieve synthesis method, a hierarchical pore structure can be formed without acid or alkali post-treatment process or addition of other components, raw material cost and subsequent separation steps are reduced, industrial amplifying production is facilitated, substance diffusion and heat conduction in methanol-to-olefin reaction are facilitated by formation of the hierarchical pores, and theservice life of the molecular sieve is greatly prolonged.

The invention relates to a method for rapid induction of homogenous polyploids of Chinese jujube, that is the method can double and further develop chromosomes of a single-cell embryo into homogenous tetraploids by simultaneously carrying out induction with colchicine during the somatic embryogenesis process of in vitro leaf blades of the Chinese jujube. The method comprises the steps of somatic embryo induction, doubling of the chromosomes, development of embryoids till nature and detection and screening of the homogenous tetraploids. The specific steps are as follows: selecting tissue culture seedling leaf blades of the Chinese jujube with robust growth and seedling age of 20-30d, and using a pair of scissors after sterilization to shear 5-8 times by being vertical to nervures; then inoculating the leaf blades in an induction culture medium MS plus 15-25g/L of maltose plus 3.0-5.0g/L of agar plus 5.0-10.0mg/L of TDZ plus 1.0-2.0mg/L of AgNO3 by leading the front surfaces to face upwards, and simultaneously adding 15-20mg/L of the colchicine into the culture medium, and carrying out dark culture for 40-50 days; transferring embryoids differentiated from calli of the leaf blades of the Chinese jujube into a hormone-free culture medium of the MS plus 40g/L of sucrose plus 500mg/L of caseinhydrolysate for lighting culture and further developing the embryoids into somatic embryo seedlings; and screening out the homogenous tetraploids from the somatic embryo seedlings through chromosome detection or the detection by a flow cytometer, wherein the pH of the culture medium is 5.0-6.0, and the culture temperature is 25-30 DEG C. The method can avoid the appearance of chimeras, omit the steps of separation and purification, rapidly obtain the homogenous polyploids and have important application value for accelerating the breeding process of the polyploids of the Chinese jujube.

The invention relates to a method for producing high-purity halogenated hydrocarbon used for liquid chromatogram by primarily rectified industrial halogenated hydrocarbon. The method comprises the following steps: eliminating unsaturated compounds by sulphuric acid, using water for extractive distillation to remove oxidizable substances, alcohols and high-hydrophilicity impurities with the similar boiling point to the halogenated hydrocarbon; using molecular sieves for water removal through absorption; and using toluene for extractive distillation to remove hydrocarbon with the similar boiling point to the halogenated hydrocarbon.

The invention discloses a polyimide composite membrane for pervaporation separation of amide/water and a preparation method thereof and belongs to the technical field of pervaporation separation. An inorganic porous base membrane is coated with a compact polyimide separated layer through a dipping and pulling process so that the polyimide pervaporation composite membrane is obtained. In order to prepare the polyimide pervaporation composite membrane with high separation performances, the main chain structure of a precursor polyamic acid resin of the separated layer polyimide membrane has symmetry groups with rigid chains (such as benzene rings) and the main chain structure contains the symmetry rigid chains. The membrane satisfies the requirements on the amide/water mixed pervaporation separation membrane in solvent resistance and selective separation and is suitable for the preparation of the pervaporation membranes.

The invention discloses a method of separation and extraction of D-lactic acid from sodium D-lactate fermentation liquid, belongs to the technical field of bio-engineering and particularly relates to the method of separation and extraction of D-lactic acid from the fermentation liquid. The method includes the steps of (1) performing solid-liquid separation to the sodium D-lactate fermentation liquid, removing proteins and pigments to obtain a clarified fermentation liquid; (2) decoloring the clarified fermentation liquid obtained in the step (1); (3) performing ion exchange to the fermentation liquid obtained in the step (2); and (4) concentrating the fermentation liquid after the ion exchange to obtain the D-lactic acid. In the method, only is normal-temperature acidification required so that the method is short in acidification time. The method is effectively reduced in the content of protein and a part of the pigments in the fermentation liquid and is free of generation of calcium sulfate which is low in additional value and is difficult to treat. The method is optimized in operation and is less in separation steps.