The invention discloses fiberglass-reinforced cement, made from, by weight: 40-50 parts of cement clinker, 5-10 parts of alkali-resistant fiberglass, 1-5 parts of mineral residue, 1-5 parts of pulverized coal residue, 5-10 parts of limestone powder, 1-5 parts of sodium methyl silicate, 1-5 parts of anionic polyacrylamide, 1-5 parts of sodium methyl silicate, and 1-5 parts of acrylic emulsion; the alkali-resistant fiberglass is 5-15 Mum in diameter and 15-30 mm in length and includes the chemical components: 60-65% of SiO2, 15-20% of Na2O, 4.0-5.0% of Al2O3, 5-10% of ZrO2, 4.0-5.0% of CaO, 5-8% of B2O3, and 0-0.7% of BaO. The invention also discloses a preparation method of the fiberglass-reinforced cement, including: subjecting the cement clinker, mineral residue, pulverized coal residue and limestone powder to mixing, crushing and calcining to obtain semi-finished cement, and adding water and the remaining materials sequentially, stirring, drying, and crushing to obtain the finished cement. The fiberglass-reinforced cement prepared herein has the advantages of high strength, alkali resistance and water resistance, and is widely applicable to the severe environments such as alkaline environments and low-temperature environments, and the cement market is widened.