The invention relates to a 2,2,6,6-tetramethyl-4-piperidinamine preparation method, which comprises: adding a raw material 2,2,6,6-tetramethylpiperidone, an amine reactant and a solvent into a reaction kettle, stirring and premixing at 10-50 DEG C to form an imine intermediate, reducing the imine intermediate by using a reducing agent at a certain temperature under a certain pressure, and reactingfor a certain time to finally synthesize the target product 2,2,6,6-tetramethyl-4-piperidinamine compound. According to the invention, 2,2,6,6-tetramethyl-4-carbonyl piperidone reacts with an amine compound to generate an imine intermediate, and a reducing agent is used for replacing catalytic hydrogenation to perform reduction, so the product yield can reach more than 92%, the generation of the2,2,6,6-tetramethylpiperidone hydrogenation byproduct tetramethylpiperidinol is avoided, the hydrogenation process with a high risk coefficient is avoided, and the method is an ideal process for achieving industrialization.