17 results about "Ethanediols" patented technology

A filter material is shown comprising a cellulose fiber-based substrate, an additive and an adhesion promoter, wherein the mass ratio of the additive and the adhesion promoter is at least 1:3 and at most 2:1, and the additive and the adhesion promoter together constitute at least 3% and at most 40% of the mass of the cellulose fiber-based substrate, wherein the additive is triethyl citrate, triacetin or a mixture of these substances, and wherein the adhesion promoter is selected from the group consisting of ethanediol, propanediol, butanediol, pentanediol and glycerin diacetate or mixtures thereof.

The invention provides an anti-neuroinflammation medicine as well as a preparation method and application thereof. The anti-neuroinflammation medicine comprises an active component and lipidosome, the active component is an inhibitor 4-aminobenzoyl hydrazine of myeloperoxidase; the liposome is prepared from phospholipid, cholesterol and distearoyl phosphatidyl ethanolamine-thioketal-polyethylene glycol; the method comprises the following steps: weighing lipidosome and 4-aminobenzoyl hydrazine, dissolving, and carrying out rotary evaporation to obtain a lipid membrane; adding a phosphate buffer solution into the lipid membrane, stirring in a water bath, performing ultrasonic treatment, filtering, centrifuging and purifying to obtain the medicine, according to the active oxygen response-based liposome delivery system disclosed by the invention, 4-aminobenzoyl hydrazine is encapsulated in liposome to form a drug, and after the drug enters a brain inflammation microenvironment area of the Alzheimer's disease, the active oxygen can break a thioketal bond, so that local release of 4-aminobenzoyl hydrazine is triggered, targeted inhibition of myeloperoxidase is realized, and the drug delivery effect is improved. The oxidative stress level is reduced, the neuroinflammation is relieved, and the cognitive impairment is effectively improved.

The invention relates to a process for preparing (hetero)aromatic compounds substituted with a hydroxyethylamino group (B) from aromatic compounds bearing an amino group (A) in the presence i) of (di)(alkyl)glycolaldehyde dimer and ii) in a reduction medium, it being understood that step i) and ii) are performed simultaneously or as a "one pot" reaction.

The invention belongs to the crossing field of traditional Chinese medicine modernization and biotechnology, and particularly relates to application of a metabolic marker in preparation of a product for auxiliary diagnosis of retinal vein occlusion (RVO) or evaluation of prognosis of treatment of RVO by ginseng-wolfberry omentum granules. The metabolic marker is selected from at least one of the following metabolites: leukotriene B4, (R)-2-feruloyl-1-(4-hydroxyphenyl)-1, 2-ethylene glycol, hyoscyamine base A6, 11, 12-epoxyeicosatrienoic acid, 3, 3 ', 4, 4'-tetrahydroxy-5, 6, 7, 8, 9, 10, 11, 12-epoxyeicosatrienoic acid, 3, 3 ', 4, 4'-tetrahydroxyl-5, 6, 7, 8, 10-tetrahydroxyl-5, 7, 8, 10 The invention relates to an anti-inflammatory agent which is prepared from 5, 5 '-diisopropyl-2, 2'-dimethyl biphenyl (3, 3 ', 4, 4', 1-ethyl piperidine, flavin mononucleotide, crystal orchid glycoside, 2-O-caffeoyl arbutin, dimethyl ellagic acid glucuronide, 4 '-hydroxy-3, 4, 5-resveratrol trimethyl ether, 3'-methoxy petamicin, phenylalanyl-leucyl-isoleucyl-tyrosine and dihydroferulic acid-4-sulfate.

The application belongs to the field of organic synthesis, and particularly relates to a method for synergistically synthesizing 1,1-diaryl-2-alkyl compounds by using nickel and light. The method comprises the following steps: using styrene derivatives, p-bromoacetophenone and tert-butyl bromide as raw materials, and mixing a metal nickel catalyst (nickel bis(acetylacetone)), a photocatalyst (1,2,3,5-tetrakis(carbazole-9-yl)-4,6-dicyano benzene), a nitrogen ligand ((4S,4'S)-1,1'-bis(3-tert-butylphenyl)-4,4',5,5'-tetrahydro-4,4'-bis[(1S)-1-methylpropyl]-2,2'-bis-4H-imidazole), a Bronsted base (N,N-dicyclohexylmethylamine), a reducing agent (1,4-dihydropyridine derivatives) and an organic solvent (glycol dimethyl ether, isopropyl ether) to generate a three-component cross-coupling reaction and synthesize 1,1-diaryl-2-alkyl compounds with one chiral center. The three-component cross-coupling reaction is realized by using nickel and light, so that the use of a metal reducing agent is avoided, and the preparation raw materials are not needed. The method has the advantages of high reaction yield, high enantiomeric selectivity, fast reaction speed, easy-to-obtain raw materials and simple process.

The invention relates to a process for preparing (hetero)aromatic compounds substituted with a hydroxyethylamino group (B) from aromatic compounds bearing a nitro(so) group (A) in the presence i) of (di)(alkyl)glycolaldehyde dimer and ii) in a reduction medium, it being understood that step i) and ii) are performed simultaneously or as a "one pot" reaction.

The invention discloses a soldering flux for welding a lead-acid storage battery, which is characterized by comprising the following components in percentage by weight: 20-25% of a deoxidant, 10-20% of an activator, 2-5% of a surfactant, 1-2% of a corrosion inhibitor, 2-3% of an additive and the balance of a solvent, the deoxidant is any one of phosphoric acid, phosphorous acid and metaphosphoric acid; the activating agent is any one of oxalic acid, succinic acid, glutaric acid, citric acid, malic acid and tartaric acid; the surfactant is any one of polyoxyethylene ether, sodium dodecyl benzene sulfonate, alkyl betaine and perfluoroalkyl sulfonate; the corrosion inhibitor is any one of triethanolamine, octadecylamine, hexadecyl trimethyl ammonium bromide, benzimidazole and benzotriazole; the additive is ethyl acetate and s-triazine in a ratio of 4: 3; the solvent is any one of ethylene glycol, propylene glycol ether, propylene glycol, glycerol and 1, 4-butanediol. The method aims to solve the problem of halogen element residues in the cast welding process of the lead-acid storage battery.

The invention discloses a cobalt plating inhibitor, a cobalt electroplating solution and an electroplating method, and belongs to the technical field of electroplating. The chemical structural formula of the cobalt plating inhibitor is shown in the specification, wherein L1, L2 and L3 are respectively and independently selected from at least one of a single bond, alkylene and polyethylene glycol; r1, R2 and R3 are respectively and independently selected from at least one of hydrogen, hydroxyl, amino, sulfydryl, carboxyl, acyl, alkyl, naphthenic base, unsaturated alkyl, aldehyde group, carboxylic acid group, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl and substituted or unsubstituted aryl ester; at least one of R1, R2 and R3 contains an unsaturated bond. The inhibitor is beneficial to filling of metal cobalt in a nanoscale interconnection groove or through hole without geometric defects, and is also beneficial to reduction of the resistivity of a metal cobalt coating.

Resins for use in toys and methods for making the same are provided. In preferred embodiments, the resins comprise 30% to 55% w / w of Ethoxylated (10) Bisphenol A Diacrylate; 20% to 35% w / w of 1,3-Hexanediol, 2-ethyl-, polymer with 1,6-diisocyanatohexane, 2-hydroxyethyl acrylate- and propylene glycol monoacrylate-blocked; 20% to 30% w / w of Hexanedioic acid, polymer with 1,2-ethanediol and 5-isocyanato-1-(isocyanatometheyl)-1,3,3-trimethylcyclohexane, 2-hydroxyethyl acrylate-blocked; 1.9%±0.5% w / w of 1-Hydroxycyclohexyl phenyl ketone; 0.43%±0.05% w / w of Ethyl trimethylbenzoyl phenylphosphinate; 0.07±0.05% w / w of Diphenyl (2, 4, 6-trimethyl benzoyl) phosphine oxide; and less than 0.19% w / w of 2-hydroxyethyl acrylate.

The invention belongs to the technical field of bacteriostatic agents, and particularly relates to pyridine ether biquaternary ammonium salt as well as a preparation method and application thereof. The method comprises the following steps: taking 3-fluoropyridine as an initial raw material, reacting with triethylene glycol to obtain 1, 2-bis (2-(pyridine-3-oxy) ethyoxyl) ethane, and carrying out quaternization reaction on the 1, 2-bis (2-(pyridine-3-oxy) ethyoxyl) ethane and brominated alkane to obtain the pyridine ether biquaternary ammonium salt. The pyridine ether biquaternary ammonium salt type bacteriostatic agent has a good bacteriostatic effect on staphylococcus aureus in gram-positive bacteria, when the concentration is 10 g / mL, the bacteriostatic rate of the bacteriostatic agent exceeds that of antibiotic erythromycin with the concentration being 40 g / mL, and the efficient and low-dosage bacteriostatic effect is achieved. The molecular structure of the pyridine ether biquaternary ammonium salt type bacteriostatic agent provided by the invention simultaneously contains three structural units with bacteriostatic activity, namely the ether bond, the pyridine ring and the quaternary ammonium salt, so that a multi-component synergistic bacteriostatic effect can be realized without compounding, and the antibacterial property is remarkably improved.

The invention discloses a bacillus subtilis alcohol dehydrogenase mutant with improved specific activity and application thereof, and belongs to the technical field of gene engineering and enzyme engineering. Amino acids at 49th, 266th and 292th sites of (2, 3)-butanediol dehydrogenase (BsBDHA) of bacillus subtilis are subjected to single mutation and combined mutation to obtain a mutant of which the specific activity and the catalytic efficiency for catalyzing (R)-1-phenyl-1, 2-glycol are remarkably improved, the specific activity reaches 2.44 U / mg or above, and the catalytic efficiency reaches 0.96 mM <-1 > s <-1 > or above; compared with BsBDHAI49L / V266L in the prior art, the (2, 3)-butanediol dehydrogenase mutant disclosed by the invention is improved by 23% or more; the catalytic efficiency of the mutant BsBDHAI49L / V266L is improved by 2.46 times or more compared with that of the mutant BsBDHAI49L / V266L in the prior art; and the conversion rate of 2-hydroxyacetophenone in 12 hours reaches 95.3%.

The invention relates to polypropylene molten aerogel high-resilience cloud wool and a preparation method thereof.The polypropylene molten aerogel high-resilience cloud wool is prepared from, by weight, 75-85 parts of polypropylene resin matrix, 8-12 parts of hydrophobic nano SiO2 aerogel powder, 6-10 parts of polyolefin elastomer, 3-5 parts of compatibilizer, 0.5-0.9 part of foaming agent, 0.5-1.0 part of initiator, 0.3-0.6 part of cross-linking agent and 0.2-0.3 part of antioxidant. The surface of the hydrophobic nano SiO2 aerogel powder is modified by a silane coupling agent, and the cross-linking agent comprises 3-mercaptopropionic acid-[2, 4, 6-trioxo-1, 3, 5-triazine-1, 3, 5 (2H, 4H, 6H)-secondary group] tris (2, 1-glycol ester) and triallyl isocyanurate, and the surface of the hydrophobic nano SiO2 aerogel powder is modified by a silane coupling agent, and the cross-linking agent comprises 3-mercaptopropionic acid-[2, 4, 6-trioxo-1, 3, 5-triazine-1, 3, 5 (2H, 4H, 6H)-secondary group] tris (2, 1-glycol ester) and triallyl isocyanurate. According to the preparation method, a cross-linking agent compounded from 3-mercaptopropionic acid-[2, 4, 6-trioxo-1, 3, 5-triazine-1, 3, 5 (2H, 4H, 6H)-secondary] tris-2, 1-glycol ester and triallyl isocyanurate is adopted, and hydrophobic nano SiO2 aerogel powder with the surface modified by a silane coupling agent and a polyolefin elastomer are uniformly dispersed in a polypropylene resin matrix, so that the polypropylene composite material is prepared. And the composite cloud velvet material has high resilience and excellent heat preservation performance at the same time.

The invention discloses a filter material comprising a cellulose-fibre-based substrate, an additive and an adhesion promoter, wherein the mass ratio of additive and adhesion promoter is at least 1:3 and at most 2:1 and the additive and the adhesion promoter make up in total at least 3% and at most 40% of the mass of the cellulose-fibre-based substrate, wherein the additive is triethyl citrate, triacetin or a mixture of these substances, and wherein the adhesion promoter is selected from the group consisting of ethanediol, propanediol, butanediol, pentanediol and glycerol diacetate or mixtures thereof.

To provide a release agent composition which is excellent in performance of removing various functional layers and ink films formed on a plastic base material, hardly causes damage such as whitening of the plastic base material due to removal of the functional layers and ink cleaning, and is excellent in performance of removing stains derived from contents in a used polyethylene terephthalate container.SOLUTION: [In the general formula (1), R1 represents an alkyl group having 4 to 18 carbon atoms or an alkenyl group having 4 to 18 carbon atoms, A1O represents an alkyleneoxy group having 2 to 4 carbon atoms, n and m represent an average number of a repeating unit of A1O and are each independently a number of 0 or more, n + m is a number of 1 to 50, and when a plurality of A1O are present, they may be the same as or different from each other.]. (A) an amine-based nonionic surfactant which is a compound represented by the following formula (I): SELECTED DRAWING: None

This invention provides a water-based inkjet ink that exhibits excellent continuous ejection stability and linear ejection, superior print density and print quality on various printing substrates, particularly paper substrates, and also good re-solubility. [Solution] A water-based inkjet ink comprising pigment particles containing a pigment and a pigment dispersion resin that covers at least a portion of the surface of the pigment, an acetylenediol-based surfactant (B-1) having a measured HLB value of 6 to 9, a siloxane-based surfactant (B-2), an alkanediol having 3 to 4 carbon atoms, an alkanediol having 5 to 8 carbon atoms, and a glycol ether having 4 to 10 carbon atoms, wherein the pigment dispersion resin contains a crosslinked product of a polymer (A-1) having an aromatic ring and an acid group and an acid value of 50 to 160 mgKOH / g and a compound (A-2) having multiple glycidyl ether groups in one molecule, and the amount of compound (A-2) blended is such that the glycidyl group content is 50 to 200 mol%.

The application discloses an oxygen-rhodamine near-infrared fluorescent dye, and a structural formula of the oxygen-rhodamine near-infrared fluorescent dye is shown in formula (a) or formula (c), wherein R1 and R2 are respectively selected from hydrogen, an alkyl group or an alkenyl group; R5-R9 are respectively selected from hydrogen, an alkyl group, a methoxy group, an ethoxy group, halogen, a carboxyl group, a sulfonic acid group, a glycol group, a hydroxyl group or an amino group, and N is an integer greater than or equal to 0. The application further discloses a preparation method and application of the fluorescent dye. The compound is novel in structure, excellent in performance, simple in preparation method, and good in application prospect.