30results about How to "Simple reactivity" patented technology

The invention discloses a method for compounding YAG single crystal nanometer powder, wherein routine inorganic salt is used as raw material to obtain a solid precursor material by a coprecipitation; supercritical water and sub-critical water are used as reaction media; the YAG single crystal nanometer powder material is compounded under the pressure of 8-30MPa and the temperature of 300 - 420 DEG C. The YAG nanometer powder material compounded by the method of the invention has the advantages that the phase is pure; the feature of the grain is a regular approximate spherical polyhedron; the distribution of the grain size is appropriate; foundation is established for preparing YAG transparent pottery laser material or device and promoting the study and development of novel laser material.

The invention relates to a method for preparing hydrogen and carbon disulfide, in particular to a method for preparing hydrogen and carbon disulfide by adopting hydrogen sulfide, which aims at solving the shortages existing in reaction (1) and reaction (4) and the problems of preparing hydrogen and carbon disulfide by combining the two reactions. The preparation method comprises the steps, hydrogen sulfide and coke are used as raw materials to generate hydrogen and carbonyl sulfide under the function of low-temperature transformation catalyst, carbonyl sulfide is separated by a cold solvent washing tower, hydrogen is separated by a hydrogen separation device, the obtained carbonyl sulfide is separated by a stripping tower or a rectifying tower so as to decompose the carbonyl sulfide into carbon dioxide and carbon disulfide under the function of low-temperature disproportionation catalyst, carbon disulfide is separated by a condenser so as to obtain carbon dioxide which is then adopted as gasification agent to prepare carbon monoxide. All reactions are carried out under low-temperature, which reduces the erosion of sulfide to equipment; the processes of the reactions and separation are simple and can be easily operated; the separated products can be used repeatedly, which reduces waste discharge and leads the industrial production to be possible.

The invention discloses a novel method for preparing epiphysin, which uses low-cost 4-propalanine as a raw material to prepare the epiphysin through steps of carboxylic esterification, amino acylation, ester reduction, hydroxyl oxidation, fischer indole cyclization and the like. The method for preparing the epiphysin uses the raw material of the 4-propalanine which has wide sources and low cost; besides, the method has high total yield and simple reaction conditions and reaction processes, avoids using expensive indole derivatives as initial raw materials in the previous documents, and provides a new choice for preparing and producing the epiphysin.

The invention discloses a method for preparing Levetiracetam. In the method, L-methionine is used as a raw material to prepare the Levetiracetam through the steps including hydroxylation of methylthio, acidylation of amido, amidation of carboxylic acid as well as cyclization. The raw material used by the method for preparing Levetiracetam is natural amino acid-L-methionine which has broad sources and low cost. Moreover, the method for preparing Levetiracetam has high total yield coefficient; the optical purity of the obtained product is high; the conditions needed for the reaction and the reaction process are simple; and an internal compensation product obtained by a complex splitting method is avoided, and a new choice is provided for preparing and producing the Levetiracetam.

The invention discloses heparin sodium detection through a proportional fluorescence method based on carbon-quantum-dot-quenched fluorescence-labeled DNA. Heparin sodium can recover the fluorescence of carbon-quantum-dot-quenched FAM-labeled DNA, with the concentration rise of heparin sodium, recovery of FAM is improved, and the original fluorescence intensity of carbon quantum dots is kept stable, thereby establishing a new ratio-type fluorescence method for heparin sodium detection. The heparin sodium detection method is simple in steps, and heparin sodium and DNA fluorescence recovery showgood linear correlation. The linear correlation is low and can reach 9.04 ng/mL. In fact, the recovery of heparin sodium in a rabbit serum sample is in a range of 95.47-111.95%. A fitted curve for simulating detection of heparin sodium in serum is close to the standard curve. Therefore, a serum sample doesn't interfere in a detection result. Compared with other heparin sodium detection methods, the method is excellent in detection performance and simple to operate. A new method selection is provided for clinical heparin sodium detection.

The invention belongs to the technical field of synthesis of pharmaceutical compounds, and particularly discloses an improved Mivacurium Chloride intermediate suitable for industrial production and amethod for synthesizing Mivacurium Chloride using the mivacurium chloride intermediate. The method uses (E)-Oct-4-ene-1,8-dioicacid and (R)-(+)-5'-Methoxylaudanosine as starting materials to prepare the Mivacurium Chloride by a two-step reaction. The starting materials are cheap and easy to obtain, and a product with a purity of 98% or more can be obtained by simple post-treatment steps such as liquid separation extraction and concentration after a first step and simple extraction or beating in a second step. The process reaction and post-treatment operation are simple, and the obtained product has high quality and can meet use requirements without further purification. The process is simple and practical, and is very suitable for industrial production.

The invention belongs to the technical field of biomass resource utilization, and discloses a method for preparing pesticide by using biomass hydrothermal carbonization liquid phase and preparing organic fertilizers by using solid phase. The method comprises the following steps: uniformly mixing biomass raw materials with water to obtain a biomass aqueous solution; then adding the biomass aqueous solution in a high-pressure reactor; replacing air in the reactor by using inert gas or hydrogen; heating to the temperature of 200-300 DEG C; carrying out constant-temperature hydrothermal carbonization reaction under the condition of stirring; filtering or centrifugally separating a reaction product; extracting the liquid phase with ethyl acetate and then preparing the pesticide; and drying the solid phase and then preparing the organic fertilizers. Compared with the traditional method for preparing pesticide and organic fertilizers by using biological oil water-phase component sugar and sugar derivatives, the method has the advantages of low energy consumption, mild reaction conditions, simple technological process, easiness in separation of the reaction products, environmental friendliness and the like.

The invention relates to preparation of a lithium cobalt phosphate-lithium vanadium phosphate composite positive electrode material for a lithium ion battery. The chemical formula of the composite material is xLiCoPO4-yLi3V2(PO4)3, wherein 0<x<=5, 0<y<=5. The preparation steps are as follows: uniformly mixing compounds of a lithium source, a cobalt source, a vanadium source and a phosphorus source; adding a carbon source and an ethyl alcohol solution, and then ball-milling in a planetary ball mill, so as to obtain precursor powder; drying in a drying oven; and transferring to a tube furnace and roasting twice, so as to obtain the target object. The preparation of the lithium cobalt phosphate-lithium vanadium phosphate composite positive electrode material for a lithium ion battery, provided by the invention has the advantages that the new-type lithium cobalt phosphate-lithium vanadium phosphate positive electrode material for the lithium ion battery is synthesized by utilizing a solid phase method for the first time, through complementation of the two materials, the new-type next-generation lithium ion battery positive electrode material which achieves security and high capacity, and balances the cycle performance with the rate capability can be obtained, manufacturing method and conversion unit are simple, conditions are easy to control, industrial scale production is easy to realize, and wide application prospect can be achieved.

The invention belongs to the technical field of photocatalysis, and particularly relates to a preparation method of litchi-like hierarchical-structure {001}-surface-exposed TiO2 powder. The method comprises the following steps: by using titanium potassium oxalate (K2TiO(C2O4)2) as a titanium source and deionized water as a solvent, preparing a titanium potassium oxalate solution; adding hydrogen peroxide (H2O2), stirring, and standing for some time; finally, adding a control agent concentrated hydrochloric acid, stirring for some time, transferring into a reaction kettle, and carrying out hydrothermal reaction at a certain temperature; and washing the obtained product with deionized water and anhydrous ethanol, and drying to obtain the litchi-like hierarchical-structure {001}-surface-exposed TiO2 powder material with high photocatalytic activity.

The invention discloses a hole transport material taking benzodithiophene diketone as a core, in which benzodithiophene diketone is taken as a core structure, two ends are directly connected with 4,4-dimethoxy triphenylamine, or connected with 4,4-dimethoxy triphenylamine end groups after different aromatic derivatives are selected as bridge groups, thus constructing a novel hole transport material with a symmetrical structure. The material has the advantages of being simple to synthesize, adjustable in energy level, high in hole mobility and conductivity, good in thermal stability and chemical stability and the like, and when the material is applied to perovskite solar cells, the photoelectric conversion efficiency of the perovskite solar cells can be improved, device stability can be enhanced, and the device preparation cost can be reduced.

The invention discloses a new method for preparing depsipeptide FK228, comprising the following steps of: firstly forming annular polypeptide in a ring-closing way through the condensation reaction of an amido bond; and then forming the coupling of sulfide-sulfide bonds through radical reaction catalyzed by iodine by using a mixed solution of methylene dichloride and methanol as a solvent so as to synthesize the FK228. The preparation method of the FK228 has the advantages of easy operation and low cost, primarily discloses a process for preparing gram-grade FK228, greatly enhances the yield compared with past literatures and patents and provides new selection for the preparation and the production of the FK228.

The invention provides a preparation method of alkyl borate. The preparation method comprises the following step: reacting by taking alkyl tosylate and bisdiboron shown as a formula I-a as raw materials under the action of a silver catalyst and alkali to obtain the alkyl borate shown as the formula I. According to the preparation method provided by the invention, commercially-available silver saltis directly adopted for participating into the reaction, a reaction system and a feeding mode are simple, and no ligand needs to be added. The used bisdiboron is insensitive to air and water and further is more convenient in actual application. The alkyl tosylate as the raw material can be conveniently prepared from alkyl alcohol and the raw material is wide in source; meanwhile, first-stage or second-stage alkyl borate is obtained by silver catalysis direct carbon-oxygen bond fission of the alkyl tosylate and the bisdiboron; the reaction has good functional group compatibility.

The invention discloses application of a phenol-substituted fullerene derivative in a perovskite solar cell, the perovskite solar cell and a preparation method of the perovskite solar cell. The perovskite solar cell comprises a conductive layer, an electron transmission layer, a fullerene derivative thin film, a perovskite layer, a hole transmission layer and an electrode which are sequentially arranged according to a layer structure, wherein the fullerene derivative can be modified on a surface of the electron transmission layer or doped in the perovskite layer. By modifying the fullerene derivative on the electron transmission layer or doping the fullerene derivative on the perovskite layer, the electron transmission performance of the perovskite solar cell can be improved, the surface defect is passivated, the magnetic hysteresis phenomenon is reduced, so that the stability and the efficiency of the solar cell are improved.

The invention relates to a clean catalysis synthesizing method for preparing 9-deoxidized-6-deoxidized-6,9-iminoether-(9a-aza-9a)-erythrocin A and 9-deoxidized-11-deoxidized-9,11-iminoether-(9a-aza-9a)-erythrocin A by means of Beckmann rearrangement of (9E)-9-deoxidized-9-hydroxyl imidogen erythrocin A in a single-phase or two-phase room temperature ionic liquid system, or for preparing 9-deoxidized-6-deoxidized-6,9-iminoether-(8a-aza-8a)-erythrocin A and 9-deoxidized-12-deoxidized-9,12-iminoether-(8a-aza-8a)-erythrocin A by means of Beckmann rearrangement of (9Z)-9-deoxidized-9-hydroxyl imidogen erythrocin A in the single-phase or two-phase room temperature ionic liquid system. The catalyst used in the method is a benzene sulfonyl chloride derivative which can generate a corresponding target product in a mild and high-transformation-rate manner. Ionic liquid used for synthesis can be recycled. The method is simple and free of pollution.

The invention relates to the field of fine chemical engineering, and particularly relates to a preparation method of 3-substituted dimethyl pentodiate and pentene diester. According to the preparationmethod of 3-substituted dimethyl pentodiate and pentene diester, malonic ester and halomethane are used as raw materials, substitution reaction is performed under an alkaline action, then decarboxylation and esterification reaction are performed so as to prepare 3-substituted dimethyl pentodiate or pentene diester, a structural formula of 3-substituted dimethyl pentodiate is as shown in a compound (V), and a structural formula of pentene diester is as shown in a compound (IX). The preparation method of 3-substituted dimethyl pentodiate and pentene diester is mild in reaction conditions, is easy to operate and is safe. The formula is shown in the description.

The invention discloses a catalyst. The main active component is one or two of Cu and Ni, the auxiliary agent is one or more simple substances or oxides of Au, Pt, Ru, Al, Re, B, Mg, Rh, Ir, Mn, La, Pd, Ag, Li, Cr and Ce, and the carrier is one or more of activated carbon, silicon oxide, aluminum oxide, graphite, a molecular sieve, diatomite and a carbon nanotube. The invention also discloses a preparation method and an application thereof. The catalyst provided by the invention has a high conversion rate and selectivity and excellent activity, stability and other properties. According to themethod, the 3-(3, 5-di-tert-butyl-4-hydroxyphenyl)propanol is prepared by hydrogenating the methyl 3-(3, 5-di-tert-butyl-4-hydroxyphenyl)propionate for the first time, and the purposes of high conversion rate and selectivity can be achieved under mild conditions through the prepared catalyst.

The invention belongs to the field of medical science, and relates to a single chain antibody-modified targeting micro-bubble ultrasonic contrast agent and a preparation method thereof. The preparation method comprises the following steps: preparing a maleimidized liposome; opening the disulfide bond of an antibody by using a reducing agent to form a mercapto group-exposed single chain antibody; linking the single chain antibody to the surface of the liposome to form a targeting liposome; and preparing the targeting micro-bubble ultrasonic contrast agent through a mechanical oscillation technology. The method can effectively improve the yield of the targeting micro-bubble ultrasonic contrast agent, and has an important application prospect in the invention and in relevant targeting micro-bubble ultrasonic contrast agent industrial production processes.

The invention discloses a synthesis method of 2,2,6,6-tetramethyl-3,5-heptadione. The synthesis method comprises the following steps: a, material feeding: mixing methyl trimethylacetate, alkali and a solvent, and uniformly stirring for 0.5 to 3 hours to obtain a mixed solution; b, reaction: continuously stirring the mixed solution in the step a under a heating condition at the temperature of 20 to 60 DEG C, slowly dripping tert-butyl methyl ketone into the mixed solution, and generating reaction at normal pressure for 8 to 48 hours to obtain reaction liquid containing a product; c, purification: adding water into the reaction liquid in the step b, uniformly stirring, and performing purification. Due to the mode, the synthesis method disclosed by the invention is easy to operate, low in cost and favorable for realizing industrialization, and can meet the technological requirement on green chemistry.

The invention discloses an integrated device and method for treating roof rainwater by a gravity type micro-filtration membrane through coupling of roof rainwater energy and electrooxidation disinfection. The device comprises a rainwater hopper, an initial rainwater discarding device, an initial water storage tank, a gravity type micro-filtration membrane tank, a check valve, a closed electrooxidation disinfection tank, a water storage tank and a water appliance. The rainwater hopper is respectively communicated with the initial rainwater discarding device and the initial water storage tank. The initial water storage tank is connected with the gravity type micro-filtration membrane tank, the gravity type micro-filtration membrane tank is connected with the closed electrooxidation disinfection tank, the closed electrooxidation disinfection tank is connected with the water storage tank, and the water storage tank is connected to the water appliance. According to the method, rainwater passes through a coupling process combining the advantages of a gravity type micro-filtration membrane technology and an electrooxidation disinfection technology, and then treated water is collected andused as living water. Roof rain energy gravity driving is adopted, energy expenditure is saved, roof rainwater can be well subjected to impurity removal, sterilization and disinfection, rainwater resources are fully utilized, and considerable economic benefits are achieved.

The invention discloses a method for preparing trimethylacetaldehyde. The method comprises the following steps: (1) firstly, carrying out a reduction reaction, namely taking pivaloyl chloride as a rawmaterial, palladium-carbon as a catalyst, acetonitrile as a reaction solvent and N,N-diisopropylethylamine as an acid-binding agent, and carrying out a reduction reaction with hydrogen; (2) secondly,carrying out filtration after the reduction reaction, namely filtering reaction liquid to obtain filtrate and a palladium-carbon catalyst, dissolving the generated organic salt into a solvent, and recycling the palladium-carbon catalyst; and (3) finally, carrying out distillation, namely distilling the filtrate, and collecting a fraction at 76-78 DEG C to obtain a trimethylacetaldehyde product, wherein the yield of the trimethylacetaldehyde product is up to 73%, and the content is greater than 98%. According to the method, common Pa/C available in the market is adopted to replace quinoline-sulfur poisoned Pa/C as a catalyst, organic tertiary amine is adopted as the acid-binding agent, and acetonitrile, DMF (Dimethyl Formamide) and lower fatty acid are adopted as solvents to replace aromatic solvents such as methylbenzene and the like, so that reaction steps and later treatment steps are simple.

The invention provides a preparation method of N, N-dimethylacetamide, which comprises the following steps: 1) enabling pentamidine hydrochloride and dimethyl acetylsuccinate to react under the action of organic amine to obtain 2-(2-n-butyl-4-hydroxy-6-methylpyrimidine-5-yl)-methyl acetate, wherein the pKa of the organic amine is 8-11.5; 2) enabling the 2-(2-n-butyl-4-hydroxy-6-methylpyrimidine-5-yl)-methyl acetate to react with dimethylamine, so as to obtain the 2-(2-n-butyl-4-hydroxy-6-methylpyrimidine-5-yl)-N, N-dimethylacetamide. The preparation method provided by the invention has the advantages of simple reaction and post-treatment process, high atom economy and low cost.

The invention discloses an aromatic boron compound of conjugated olefin as well as a preparation method and application of the aromatic boron compound. The preparation method comprises the following steps: in an inert atmosphere, adding materials and a solvent into a reaction container, uniformly mixing, placing the reaction container in an oil bath at 80-120 DEG C, violently stirring and reacting for 18-36 hours to obtain a reaction product; the material comprises a conjugated olefin compound, an aryl bromide compound, bis (pinacolato) diboron, a palladium catalyst, a ligand compound and alkali. And purifying the reaction product to obtain the aromatic boron compound of the conjugated olefin. The preparation method has the characteristics of high yield, mild reaction conditions, simple reaction and post-treatment purification process, easiness in operation and the like, and the obtained compound has good regioselectivity, chemical selectivity and functional group compatibility and can be used for removing a guiding group 8-aminoquinoline in a 1, 6-dicarbonyl skeleton compound.

The invention relates to a preparation method of a self-supporting metal sulfide air electrode. The method comprises the following steps: (a), dissolving soluble cobalt salt, soluble nickel salt and aprecipitant in water to form a mixed solution, and transferring the mixed solution into a first hydrothermal reaction kettle; and setting the molar ratio of the soluble cobalt salt to the soluble nickel salt to the precipitant to be (1-3): 1: (3-5); (b), adding a current collector into the first hydrothermal reaction kettle to enable the current collector to be immersed in the mixed solution; then heating the first hydrothermal reaction kettle to carry out hydrothermal reaction in the first hydrothermal reaction kettle so as to grow a nickel-cobalt precursor on the surface of the current collector; (c), putting the current collector on which the nickel-cobalt precursor grows into a second hydrothermal reaction kettle containing a sulfide aqueous solution, and heating the second hydrothermal reaction kettle to carry out hydrothermal reaction in the second hydrothermal reaction kettle; and (d), placing the current collector obtained in the (c) in an inert gas atmosphere, and performingcalcining at a temperature of s300-500 DEG C. And a NiCo2S4 nanotube array with a hollow tube shape, a self-supporting structure and high conductivity can be formed on the current collector.

The invention discloses a real-time fluorescent nucleic acid isothermal amplification detection kit for treponema pallidum 16s RNA, and a special primer and a probe thereof, and belongs to the technical field of biomedical detection. The kit provided by the invention comprises a nucleic acid extracting solution, a detection solution a, a detection solution b and an SAT enzyme solution, the primers and the probes which are more suitable for treponema pallidum 16s RNA detection are optimally designed, and the components are added step by step in the detection process to perform step-by-step reaction, so that rapid and accurate detection of treponema pallidum 16s RNA can be realized, and the kit is high in sensitivity and high in sensitivity. And the amplification product RNA is easy to degrade and does not cause sample cross contamination and environmental pollution.

The invention discloses a novel method for synthesizing 2-chloro-5-aminophenol, which takes m-aminophenol or m-nitrophenol as a raw material and takes a microreactor or a common reactor as reaction equipment. A selective chlorinating agent N-chloro succinimide (or N-chloro polymaleimide) or chlorine gas quantitatively synthesized on site is used for performing micro-region selective chlorination to obtain the 2-chloro-5-aminophenol. The method has the advantages of cheap and easily available raw materials, simple reaction operation, simple post-treatment, environmental protection, and realization of continuous production.

The invention provides a synthesis method of 2-phenyl anthracene, which comprises the following steps: reacting 2, 3-dibromonaphthalene with n-butyllithium and N, N-dimethylformamide to generate 2-formyl-3-bromonaphthalene; 2-formyl-3-bromonaphthalene and styrene are subjected to a Heck reaction, and 2-formyl-3-styryl naphthalene is generated; the 2-formyl-3-styryl naphthalene, chloromethyl ether triphenylphosphine salt and potassium tert-butoxide are subjected to a Wittig reaction, and 2-methoxyvinyl-3-styryl naphthalene is generated; and carrying out ring closing on the 2-methoxyvinyl-3-styryl naphthalene through methanesulfonic acid to prepare the 2-phenyl anthracene. The synthesis method of 2-phenyl anthracene provided by the invention adopts the raw materials with low price, the reaction process and post-treatment are simple, the harm to the environment is small, the production cost is reduced, the yield is high, and the synthesis method is suitable for industrial production.

The present invention discloses a effective preparation method of a cyclic methylene disulfonate compound with low cost and high purity. In the presence of oxygen and a dehydrating agent, methylal andan alkyl disulfonic acid compound are subjected to a pressurization reaction at a certain temperature under the action of a catalyst, and the high-purity cyclic methylene disulfonate compound can beobtained through a simple post-treatment purification process. The method is mild in reaction condition, simple and environment-friendly in process, convenient to operate, wide and cheap in raw material source, high in product yield and purity and low in preparation cost. The obtained cyclic methylene disulfonate compound can be used as a power lithium battery electrolyte additive.

The invention discloses a synthetic method of an efficient high-stability catalyst for an aqueous phase click reaction. The synthetic method comprises the following steps of synthesizing a water-soluble multi-dentate triazole ligand by virtue of a multi-step organic reaction, and coordinating the water-soluble multi-dentate triazole ligand with copper salt to form a cuprous catalyst. Due to the special and stable structure, the catalyst has the characteristics that the water solubility is good, the catalytic efficiency is high, and the catalyst can stably exist in air, can be used in an acid or alkali environment and can effectively resist the interference of primary amine or halide ions; the efficient high-stability catalyst has bright prospects in various fields spanning over a plurality of subjects such as designed synthesis and modification of water-soluble polymers, combinatorial chemistry, surface modification, medicinal chemistry and molecular biology.

The invention relates to a reaction system and method for preparing ethylene by using a slurry bed reactor. The system comprises the slurry bed reactor, a condenser, a condensation separator, a solvent pump, a solvent mixing tank, a solvent temperature control system, filter equipment, a green oil removing system, a high-temperature heating device and a catalyst reduction device, wherein the solvent temperature control system comprises a heater, a solvent bypass and a cooler; the solvent mixing tank communicates with the slurry bed reactor; the filter equipment communicates with the slurry bed reactor; the condenser communicates with the slurry bed reactor; the solvent temperature control system communicates with the slurry bed reactor; the condenser, the condensation separator and the solvent mixing tank communicate with one another successively; the solvent mixing tank, the solvent pump and the solvent temperature control system communicate with one another successively; the filter equipment, the high-temperature heating device, the catalyst reducing device and the solvent mixing tank communicate with one another successively; and the filter equipment, the green oil removing system and the solvent mixing tank communicate with one another successively. By the reaction system and method, the problems that heat inside prepared ethylene cannot be transferred out easily, and the utilization rate of a catalyst is low can be solved effectively.

The invention relates to a preparation method for dimemorfan phosphate and preparation methods of dimemorfan phosphate intermediates, and belongs to the field of pharmaceutical chemicals. The invention provides the synthesis method of the dimemorfan phosphate intermediate 2-(4-methylphenyl)-N-[(cyclohexen-1-yl)ethyl]acetamide. The 2-(4-methylphenyl)-N-[(cyclohexen-1-yl)ethyl]acetamide is preparedby reacting 2-(1-cyclohexenyl)ethylamine with p-methylphenylacetic acid. The invention also provides the synthesis method of the other dimemorfan phosphate intermediate 1-(4-methylbenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline. The 1-(4-methylbenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline is prepared by reducing 1-(4-methylbenzyl)-3,4,5,6,7,8-hexahydroisoquinoline. The invention also provides the preparation method for preparing dimemorfan phosphate from (9alpha,13alpha,14alpha)-3-methylmorphinan-17-carboxaldehyde. The invention further provides a total synthesis method for preparing dimemorfanphosphate from the intermediates. The methods have the advantages of mild reaction conditions, no dangerous reagents, obtaining of high-purity dimemorfan phosphate through a common salt forming reaction and recrystallization, simplicity in post-treatment, and suitableness for industrial large-scale production.