The invention provides a preparation method of a HAp blended silver and copper antibacterial composite coating. The method comprises the following steps: first, conducting ultrasonic cleaning treatment on the artificial ligament surface, conducting friction by using the steel grit, cleaning by distilled water, and conducting vacuum drying; second, mixing gelatin and a calcium source solution, adding silver and copper sources to form a mixed solution, regulating the pH value, stirring, soaking artificial ligament in the mixed solution, and stirring; and third, remove the taking out the artificial ligament, drying with filter paper, dipping in a Na2HPO4 solution, stirring, standing, drying with filter paper, and repeating cycles of mineralization. The invention uses a biomimetic mineralization method to form the HAp blended silver and copper antibacterial agent composite coating with uniform mineralized structure and stable performance on the artificial ligament surface by using gelatin as the mineralization template. The coating modifies the artificial ligament and further realizes surface modification on artificial ligament, so that the artificial ligament has antibacterial and anti-inflammatory properties to reduce postoperative synovitis and complications such as infection of cruciate ligament reconstruction of knee joint.