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81results about How to "The preparation process is easy to obtain" patented technology

Sirolimos sustained and controlled release preparation and preparation method thereof

InactiveCN101361703AOvercome the problems of poor water solubility and narrow therapeutic windowImprove securityOrganic active ingredientsPharmaceutical delivery mechanismSolubilityCyclodextrin
The invention provides a Sirolimus slow controlled release preparation and a preparation method thereof. By adopting the solubilizing methods including a solid dispersion technology or cyclodextrin inclusion technology or adding one or a plurality of surface active agents after micronizing drugs and the like, the solubility is dramatically improved and further the bioavailability is improved, therefore, a matrix type slow controlled release preparation is made by adding one or a plurality of framework materials and other accessories, or a diaphragm-controlled or osmotic pump type slow controlled release preparation is made by adopting slow controlled release materials for coating. The Sirolimus slow controlled release preparation has better solubility and dissolution rate, high bioavailability as well as slow controlled release effect, thus being capable of maintaining steady blood concentration, bringing down the concentration of peak, reducing the occurrence of adverse reaction and improving the safety of clinical medicines, in addition, the raw materials can be acquired easily, the preparation process is simple and feasible with high yield rate and low cost, and the large-scale industrial production can be realized and the economic benefit is marked.
Owner:宋洪涛

C230-strength-grade ultrahigh-performance fiber reinforced concrete containing coarse aggregates and preparation method of C230-strength-grade ultrahigh-performance fiber reinforced concrete

The invention discloses C230-strength-grade ultrahigh-performance fiber reinforced concrete containing coarse aggregates and a preparation method of the C230-strength-grade ultrahigh-performance fiber reinforced concrete. The concrete comprises the following components in parts by mass: 560 parts of cement, 64 parts of water, 900 parts of detritus, 780 parts of fine aggregates, 75 parts of fly ash, 63 parts of rice hull ash, 145 parts of silica fume, 16 parts of water reducing agent, 11 parts of excitant, 1.7 parts of cellulosic fiber, 78 parts of steel fiber, 50 parts of hydroxyl modified carbon nanotube dispersion liquid, 52 parts of graphene oxide dispersion liquid and 2.9 parts of defoaming agent. The prepared concrete has relatively high toughness and durability and relatively high bonding strength with profile steel and has the compressive strength of 235.48MPa, the breaking strength of 48.23MPa and the split tensile strength of 22.95MPa, the bonding strength of the C230-strength-grade ultrahigh-performance fiber reinforced concrete and the profile steel reaches 9.24MPa, and the impermeability grade of chloride ions reaches the VI grade. When being used in a profile steel and concrete combined structure, the C230-strength-grade ultrahigh-performance fiber reinforced concrete containing coarse aggregates is capable of effectively exerting the cooperative working performance between the profile steel and the concrete and making up the defects that the bonding performance of the profile steel and the concrete is poor and the respective mechanical performances of the profile steel and the concrete cannot be sufficiently exerted.
Owner:XI'AN UNIVERSITY OF ARCHITECTURE AND TECHNOLOGY

Vein and artery relieving pills for impediment of sinew

The invention relates to vein and artery relieving pills for sinew impediment, which belong to Chinese medicament product. The pills are prepared from the following raw materials in part by weight: 1 to 2 parts of processed common monkshood mother root, 1 to 2 parts of processed kusnezoff monkshood root, 1 to 2 parts of processed pedate pinallia jackinthepulpit rhizome, 1 to 2 parts of earthworm, 0.3 to 1 part of processed frankincense , 0.3 to 1 part of processed myrrh, 0.3 to 1 part of scorpion, 0.3 to 1 part of entipede withtout head and feet, 0.5 to 1.5 parts of ground beetle, 0.3 to 1 part of Sanchi, 0.5 to 1.5 parts of dragon's blood, 0.3 to 1 part of Chinese angelica, 1 to 2 parts of white paeony root, 1 to 2 parts of szechuan lovage rhizome, 1 to 2 parts of common floweringquince fruit, 1 to 2 parts of medicinal cyathula root, 1 to 2 parts of clematis root, 1 to 2 parts of Chinese atractylodes rhizome, 1 to 2 parts of east Asian tree fern rhizome without hair, 0.3 to 1 part of liquoric root, 1 to 2 parts of garter snake, 0.3 to 1 part of sanguisuga and 0.3 to 1 part of stiff silkworm. A part of raw materials are ground into fine powder; the rest raw materials are decocted to make a medicine juice; then the medicine juice is evenly mixed with the fine powder to granulate; and granules are dried to obtain a product. The pills have the effects of dissipating cold and eliminating dampness, transforming phlegm, tracking wind and freeing network vessels, quickening blood and transforming stasis, dissipating binds and relieving pain, supplementing liver and kidney, strengthening sinew and bone, and harmonizing construction and defense, has good curative effects on various kinds of sinew impediment, is convenient to use and has no toxic or side effect.
Owner:向国强

Preparation of different active positions of artemisia sacrorum extract and application of artemisia sacrorum extract serving as acaricidal active substance

The invention discloses a preparation of different active positions of an artemisia sacrorum extract. The preparation method comprises the following steps: drying overground parts of fresh artemisia sacrorum plants at a maturation stage in shade, crushing, carrying out alcohol extracting, carrying out vacuum concentrating and drying to obtain the artemisia sacrorum extract; dissolving the artemisia sacrorum extract in distilled water, sequentially extracting by using petroleum ether, ethyl acetate and normal butanol to obtain four different active parts of petroleum ether, ethyl acetate, normal butanol and aqueous phase. An acaricide prepared by using the artemisia sacrorum as a plant source has very obvious contact toxicity on agricultural mites, has a growth-promoting effect on crops, improves the productivity and stress resistance of the crops in a mite killing process and promote the increase of yield and income in agricultural production. As a safe, non-toxic and environment-friendly plant source pesticide, the artemisia sacrorum extract is environmentally friendly, is safe to natural enemies of pests and people and livestock, and has great significance of establishing novel green ecological agriculture.
Owner:LANZHOU UNIVERSITY

Preparation method of special rice fertilizer with comprehensive nutrients

The invention discloses a preparation method of a special rice fertilizer with comprehensive nutrients, comprising the following steps: stirring sodium nitrate, ammonium sulfate, a potassium magnesiumphosphate fertilizer, vermiculite powder, fly ash, Chinese medical stone powder, borax and coconut shell carbon powder, sending the materials into a melting tank and heating and stirring, heating andcontinuously stirring, and filtering to obtain a melt; mixing furfural residue, corn germ meal, fermented oil residue, pigeon dung, propolis, magnesium citrate and ferrous sulfate, adding water, grinding, heating, adding an ammonium chloride compound and the melt and uniformly mixing to obtain pulp, sending the pulp into a rotary pulp shooting machine (a pulp shooting port of the rotary pulp shooting machine is positioned above a drying tower), letting the pulp be sprayed into fertilizer drops above the drying tower from the pulp shooting port of the rotary pulp shooting machine, and settlingand drying in the drying tower so as to obtain the special granular rice fertilizer. The preparation technology is simple. The fertilizer has more comprehensive and balanced nutrients and can be usedto efficiently provide rice with nutrients for a long time. Labor cost is low, labor force can be saved, and environmental pollution is reduced.
Owner:芜湖四高农业科技有限公司

Flame-retarding liquid and preparation method of flame-retarding liquid

The invention discloses flame-retarding liquid and a preparation method of the flame-retarding liquid. The flame-retarding liquid is prepared from the following components in parts by weight: 100 parts of water-soluble polyesteramide, 30 to 100 parts of starch, 1 to 5 parts of phosphomolybdic acid, 1 to 3 parts of nickel aminosulfonate, 40 to 60 parts of melamine, 80 to 180 parts of phytic acid, 20 to 35 parts of ethylene urea, 400 to 700 parts of water and 80 to 185 parts of sodium methyl silicate through mixing and reacting. The preparation method can be implemented according to the following steps: mixing the melamine, the phytic acid, the ethylene urea and the water and reacting; then adding the water-soluble polyesteramide, the starch, the phosphomolybdic acid and the nickel aminosulfonate and heating to carry out the second time of reaction; then adding the sodium methyl silicate, and cooling and carrying out the third time of reaction; finally, ageing and standing at room temperature, and filtering to remove dreg. The flame-retarding liquid disclosed by the invention is water-based flame-retarding liquid and does not contain halogen and aldehydes substances; the flame-retarding liquid is used as a flame-retarding coating and has good flame-retarding and weather-resisting performances.
Owner:FUJIAN UNIV OF TECH

Preparation method of fertilizer special for rice and capable of reducing labor cost

The invention discloses a preparation method of fertilizer special for rice and capable of reducing the labor cost. The method includes the following steps of stirring ammonium chloride, chitosan, water and paraffin, adding formaldehyde in a stirring state, continuing stirring, adding absolute ethyl alcohol, adjusting the pH value of a system and carrying out filtering and washing to obtain a first material; stirring the first material, ammonium nitrate, ammonium bicarbonate, triple superphosphate, montmorillonoid, calcined kaolin, expanded perlite, borax and coal gangue, conveying the mixtureto a fusion tank for heating and stirring, raising the temperature, continuing stirring and conducting filtering to obtain a second material; mixing manioc dregs, shrimp head meal, distillers' grains, mushroom dregs, royal jelly, zinc humate and 6-urea iron trinitrate, adding water, conducting grinding, raising the temperature, adding the second material for even blending to obtain slurry, and conveying the slurry into a rotary slurry spraying machine, wherein a slurry spraying port of the rotary slurry spraying machine is positioned above a drying tower, the slurry is sprayed into fertilizerliquid drops above the drying tower from the slurry spraying port of the rotary slurry spraying machine, and the slurry subsides and is dried in the drying tower to obtain the granular fertilizer special for the rice.
Owner:芜湖四高农业科技有限公司

Preparation method of Chinese chestnut peel extract containing ceramide

The invention discloses a preparation method of Chinese chestnut peel extract containing ceramide. The preparation method comprises the following steps: S1, taking Chinese chestnut peel raw materialsand crushing; adding an extracting solvent and extracting; decompressing extracting filtrate to recycle the solvent; concentrating in vacuum to obtain concentrated extract; S2, adding an alkaline solution into the extract and carrying out hydrolysis to obtain hydrolysate; S3, carrying out macroporous resin column separation on the hydrolysate and washing a resin column with water until flowing-outliquid is colorless; eluting and collecting an eluting solution; decompressing and concentrating; drying to obtain Chinese chestnut peel crude extract; S4, dissolving the Chinese chestnut peel crudeextract with alcohol and eluting on the column; carrying out thin layer chromatography detection; collecting fractions by sections; combining the fractions and concentrating and drying to obtain the Chinese chestnut peel extract. According to the preparation method disclosed by the invention, ceramide substances are extracted from Chinese chestnut peels; the raw materials are easy to obtain and are green and environmentally friendly; a preparation technology is simple and easy to control; the quality of a product is stable and the production cost is low; the content of the ceramide in the obtained extract can reach 95 percent.
Owner:烟台新时代健康产业日化有限公司

Long-acting slow-release fertilizer used in planting early stage of Pseudostellaria heterophylla and preparation method thereof

InactiveCN109503260ASolving Supplement Long-Acting IssuesReduce fertilizer useSuperphosphatesBioloigcal waste fertilisersLong actingFertilizer
The invention discloses a long-acting slow-release fertilizer used in a planting early stage of Pseudostellaria heterophylla and a preparation method thereof. The long-acting slow-release fertilizer comprises a fertilizer component and is formed through the steps that the fertilizer component is adsorbed by porous starch, and uniformly mixed with a water-soluble solid powder-like carbon source anda carrier material and mutually dissolved, and then solidified and smashed into particles, wherein a using proportion of the fertilizer component : the porous starch : the water-soluble solid powder-like carbon source and the carrier material is 1:1:(1.2 to 1.5). The preparation method comprises three steps of uniformly mixing fertilizer component, adsorbing and coating. According to the long-acting slow-release fertilizer, based on biology and cultivation characters of the Pseudostellaria heterophylla, the fertilizer component is innovatively coated with a slow release system, thus effectively solving a fertilizer replenishing and long-acting problem that the Pseudostellaria heterophylla likes the fertilizer but not resistant to the fertilizer; meanwhile, a dosage of the fertilizer is reduced, an utilization ratio of the fertilizer is improved, the fertilizer is only needed to be applied once without topdressing, the applying is convenient, labor-saving and safe, the fertilizer efficiency after applying is stable and, and is powerful in later stage, and disease-resistant and lodging-resistant effects, yield increasing and plant soil pollution reduction are realized.
Owner:FUJIAN BRADY PHARMA CO LTD

Absorbable spongy bone wax with hemostatic and bone healing promoting functions and preparation method of absorbable spongy bone wax

The invention discloses a preparation method of absorbable spongy bone wax with hemostatic and bone healing promoting functions. The preparation method comprises the following steps: uniformly mixingquaternized chitosan / modified starch composite microspheres with beta-tricalcium phosphate and a silk fibroin solution, and performing freeze drying to obtain the absorbable spongy bone wax. The absorbable spongy bone wax with hemostatic and bone healing promoting functions is prepared by combining a specific raw material ratio with a preparation process. Due to the fact that the raw materials have good biocompatibility and can be absorbed by the human body, the prepared spongy bone wax can be absorbed by the human body, residues are avoided, and bone wound healing is facilitated. Secondly, due to the action of the quaternized chitosan / modified starch composite microspheres, the bone wax has a good hemostatic effect, has certain antibacterial and anti-inflammatory effects, and has a good effect of promoting bone wound healing. Beta-TCP with bone induction and bone guidance effects is also added into the bone wax, so that the bone wax can promote repair of bone defect parts in bone wounds.
Owner:GUANGZHOU CHUANGSAI BIOLOGICAL MEDICAL MATERIALS CO LTD
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