99 results about "Succinamopine" patented technology

The invention discloses an OCA optical adhesive and a preparation method thereof, and relates to the technical field of adhesives, and the OCA optical adhesive is prepared from the following raw materials in parts by weight: 35-45 parts of acrylate-terminated hyperbranched organosilicon modified polyurethane, 2-4 parts of allyl succinimido carbonate, 1-3 parts of hexafluorobisphenol A diacrylate, 1-3 parts of 1, 2, 4-trimethyl-1, 3-pentanediol monoisobutyrate, 1-3 parts of 1, 3-pentanediol monoisobutyrate, 1-3 parts of 1, 3-pentanediol monoisobutyrate, 1-3 parts of 1, 3-pentanediol The invention relates to a photocurable adhesive, which is prepared from the following components in parts by weight: 20 to 30 parts of a diluent, 0.6 to 1.2 parts of a photoinitiator, 0.5 to 1 part of an antioxidant and 0.5 to 1 part of a de-foaming agent. The photocurable adhesive is prepared from the following components in parts by weight: 1 to 5 parts of 1, 3-bis (oxiranyl methyl)-5-(2-propenyl)-1, 3, 5-triazine-2, 4, 6 (1H, 3H, 5H)-triketone, 3 to 5 parts of 2, 2 '-bis (trifluoromethyl) diaminodiphenyl, 6 to 8 parts of other polymerizable monomers, 20 to 30 parts of the diluent, 0.6 to 1.2 parts of the photoinitiator, 0.5 to 1 part of the antioxidant and 0.5 to 1 part of the de-foaming agent. The OCA optical adhesive is good in bonding performance, sufficient in weather resistance and environmental protection performance and good in oil resistance.

The invention belongs to the technical field of lithium ion batteries, and discloses an amidated polyacrylic acid water-based polymer binder for a silicon-based negative electrode of a lithium ion battery and a preparation method and application of the amidated polyacrylic acid water-based polymer binder for the silicon-based negative electrode of the lithium ion battery. The preparation method comprises the following steps: under a protective atmosphere, sequentially adding 1-ethyl-(3-dimethylaminopropyl) carbodiimide hydrochloride, N-hydroxysuccinimide and levodopa, stirring to fully react, carrying out dialysis freeze-drying treatment to obtain a primary product PL, and uniformly mixing the PL with glycerol to obtain the product. According to the binder, a dynamic bond is successfully introduced, the transportation efficiency of lithium ions is improved, a three-dimensional network structure is constructed, adverse stress generated by volume expansion of a SiOx negative electrode material in the charging and discharging process of an electrode can be effectively inhibited, and the SiOx negative electrode shows good cycling stability.

The invention belongs to the technical field of lithium ion batteries, and discloses a carbon compatible binder for a silicon-carbon negative electrode of a lithium ion battery and a preparation method and application of the carbon compatible binder for the silicon-carbon negative electrode of the lithium ion battery. Then N-hydroxysuccinimide and 1-ethyl-(3-dimethylaminopropyl) carbodiimide are added to activate carboxyl of sodium carboxymethyl cellulose, finally 1-pyrene methylamine hydrochloride is added, N2 is introduced at the room temperature, and a reaction is performed under stirring. According to the binding agent, sodium carboxymethyl cellulose is used as a main chain to be subjected to amidation reaction with 1-pyrene methylamine hydrochloride, pi-pi conjugation can be formed by introduced pyrene groups and graphite in a silicon-carbon material, the interface compatibility of the binding agent and the silicon-carbon material can be effectively improved, the dispersity and the binding property of the silicon-carbon material are enhanced, and the binding agent can be used for preparing the silicon-carbon material. And the electrochemical performance of the silicon-carbon negative electrode of the lithium ion battery is obviously improved.

The invention discloses a preparation method of an optical OCA (Optical Clear Adhesive) and application of the optical OCA in a mobile phone folding screen, and relates to the technical field of optical cement, the optical OCA is prepared from the following raw materials in parts by weight: 50 parts of acrylate prepolymers, 2-4 parts of 3-allyl-2-mercapto-3H-quinazoline-4-ketone, 1-3 parts of diallyl disulfide, 1-3 parts of 3-[N, N-dimethyl formamide], 1-3 parts of 2, 3, 5-trimethyl-1, 3-pentanediol monoisobutyronitrile, 1-3 parts of 2, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3 The preparation method comprises the following steps: adding 3-5 parts of N, N-dimethyl-[2-(2-methylpropane-2-enoyloxy) ethyl] ammonium] propane-1-sulfonic acid inner salt, 1-3 parts of allyl succinimido carbonate, 2-4 parts of dicyclopentene methacrylate, 1-3 parts of 1, 3, 5-triacryloyl hexahydro-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5-trimethyl-1, 3, 5- The invention relates to a graphene quantum dot photoinitiator which is prepared from the following components in parts by weight: 1-3 parts of 1, 3, 5-triazine, 0.8-1.2 parts of a photoinitiator, 1-3 parts of an aziridine cross-linking agent, 1-3 parts of graphene quantum dots, 0.8-1.2 parts of a coupling agent and 40-50 parts of a diluent. The optical OCA adhesive is high in light transmittance and bonding strength, good in weather resistance and excellent in folding resistance.

The invention provides antibacterial carboxymethyl cellulose hemostatic gauze and a preparation method thereof.The preparation method comprises the steps that carboxymethyl cellulose gauze is soaked in a PBS buffer solution, N-hydroxysuccinimide and 1-ethyl-(3-dimethylaminopropyl) carbodiimide are added into the PBS buffer solution, and a soaking solution is obtained after uniform mixing; adding the graft modified alginate oligosaccharide into the soaking solution, mixing and stirring to generate grafting reaction, taking out the carboxymethyl cellulose gauze after the reaction is finished, washing and drying to obtain the antibacterial carboxymethyl cellulose hemostatic gauze. According to the preparation method disclosed by the invention, the catechol-grafted modified alginate oligosaccharide and partially carboxymethylated carboxymethyl cellulose gauze are subjected to amidation grafting compounding, so that the hemostatic gauze with excellent antibacterial and hemostatic properties is prepared.

The invention discloses a bamboo hard carbon material, comprising the following components in parts by weight: 65-70 parts of bamboo powder, 6-8 parts of phosphoric acid, 5-7 parts of ethylenediamine, 4-6 parts of N-hydroxysuccinimide, 3-6 parts of 2,5-furan dimethanol, and 80-90 parts of deionized water. The bamboo hard carbon material is prepared by the following method: bamboo is pre-treated and carbonized, ball-milled to obtain 500-mesh bamboo powder, then mixed with phosphoric acid, ethylenediamine, N-hydroxysuccinimide, 2,5-furan dimethanol, deionized, dried, filtered to obtain modified bamboo powder, and then the modified bamboo powder is carbonized at high temperature and plasma treated to obtain the bamboo hard carbon material. The bamboo hard carbon material prepared by the present invention can be used as a negative electrode material of an ion battery, which can effectively improve the specific capacity, initial coulomb efficiency, and rate performance of the ion battery, and enhance its cycle stability, prolong service life, and the production process is simple and easy to promote.

The invention provides a polyethylene glycol derivative-collagen cartilage repair gel which is characterized by being prepared from the following components in parts by weight: 8 to 12 parts of collagen (namely COL) solution, 0.5 to 2 parts of polydeoxyribonucleotide (namely PDRN), 4 to 8 parts of polyethylene glycol disuccinimide succinate (namely SS-PEG-SS) solution and 0.1 to 0.4 part of tannic acid (namely TA), and particularly discloses a preparation method and application of the polyethylene glycol derivative-collagen cartilage repair gel. In a word, the composite gel and the collagen are subjected to efficient amidation reaction through SS-PEG-SS to form a stable three-dimensional network, so that the structural support of the type I collagen, the tissue repair of PDRN and the anti-inflammatory and anti-oxidation characteristics of tannic acid are successfully integrated; therefore, the composite material has the comprehensive performance of good structural stability, high mechanical strength, good biocompatibility, controllable degradation period, excellent needle passing performance and the like, and shows the wide application prospects of clear repair effect, remarkable component synergistic effect, mature production process, outstanding cost effectiveness and the like.

The invention discloses a bletilla striata polysaccharide gel patch for wound repair and a preparation method of the bletilla striata polysaccharide gel patch, and relates to the field of high polymer materials. When the bletilla striata polysaccharide gel patch for wound repair is prepared, graphene oxide sequentially reacts with 3-methylaminopropylamine and 4-(N-maleimidomethyl) cyclohexane-1-carboxylic acid succinimide ester, and modified graphene oxide is prepared; the preparation method comprises the following steps: extracting bletilla striata polysaccharide from bletilla striata, and reacting the bletilla striata polysaccharide with maleic anhydride and N-methyldopamine in sequence to prepare modified bletilla striata polysaccharide; and reacting the modified bletilla striata polysaccharide, the modified graphene oxide and 1, 5-dibromopentane, mixing with deionized water, coating, and preparing a film, so as to obtain the bletilla striata polysaccharide gel patch for wound repair. The bletilla striata polysaccharide gel patch for wound repair, prepared by the invention, has antibacterial, high-adhesion and antioxidant capacities.

The present application relates to the field of wastewater treatment. Provided are a selective adsorption material for treating selenium-containing wastewater, a preparation method therefor, and a method using same for treating selenium-containing wastewater.The preparation method comprises: thermally treating active charcoal by using nitric acid, washing same to be neutral, and carrying out constant-temperature drying to obtain modified active charcoal; mixing magnesium chloride, ethanol, dodecyl trimethyl ammonium chloride and 2-mercaptoethanol to obtain a loading solution; mixing the modified active charcoal, the loading solution and sulfosuccinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt, adding ammonium hydroxide to regulate the pH value of the solution to 10-11, and then sequentially carrying out first heating treatment and second heating treatment to obtain a primary adsorption material; and cleaning the primary adsorption material, and then performing vacuum drying. The material prepared by the method provided in the present application can enable treated wastewater to reach the primary standard limit value (0.1 mg / L) of integrated wastewater discharge standard, and has high adsorption efficiency and low treatment cost.

The invention provides a method for improving the stability of a dentin bonding interface through phosphorylated chitosan, and belongs to the field of biological medicine. The preparation method comprises the following steps: mixing phosphorylated chitosan with 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide and N-hydroxysuccinimide, and uniformly coating the mixture on the surface of dentin to form a covalent cross-linked network and induce in-situ deposition of hydroxyapatite. A series of performance changes are brought to a dentin bonding interface, and the mechanical strength and the enzymolysis resistance of dentin collagen fibers are improved. The adhesive interface is endowed with the capability of inhibiting bacteria, so that the demineralized dentin collagen fibers are preserved, and the adhesive interface is stabilized. The dentin collagen fiber is stabilized, a proper remineralization microenvironment is maintained, the deposition of minerals such as calcium and phosphorus on the surface of the dentin is promoted, and meanwhile, a guarantee is provided for the dentin to resist demineralization. According to the invention, the three problems of micro leakage, collagen degradation and remineralization are simultaneously solved in the field of dentin bonding for the first time.

The invention discloses periodontitis targeted sustained-release gel based on epithelial training immunization and a preparation method thereof, and relates to the technical field of biological medicine, and the preparation method comprises the following steps: modifying poloxamer, and dissolving the modified poloxamer in anhydrous acetonitrile; the preparation method comprises the following steps: dissolving RGD peptide in a PBS (Phosphate Buffer Solution), adding N-hydroxysuccinimide and 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide, and activating to obtain an activated RGD peptide solution; adding the activated RGD peptide solution into the modified poloxamer solution, and reacting at room temperature to obtain RGD peptide modified poloxamer; the RGD peptide modified poloxamer solution is mixed with a beta-glucan solution and a TLR2 agonist solution, and the periodontitis targeted slow-release gel is obtained. The gel provided by the invention specifically targets gingival epithelial cells, reduces inflammatory response and promotes periodontal tissue regeneration, has good biocompatibility and slow release performance, and can effectively control periodontitis and prevent relapse.

The invention belongs to the field of material science and clinical medicine, and particularly relates to a succinic acid polymer and a preparation method and derivative thereof, adhesive hydrogel and a preparation method and application thereof. According to the specific technical scheme, the succinic acid polymer is provided, and the succinic acid acrylate polymer is prepared by modifying the succinic acid polymer through acryloyl chloride; further uniformly mixing a succinic acid acrylate polymer, acrylic acid, dimethylaminoethyl methacrylate and acrylic acid N-hydroxysuccinimide ester with a photoinitiator phenyl-2, 4, 6-trimethylbenzoyl lithium phosphite, and reacting under the irradiation of ultraviolet light to obtain the photoinitiator. The three-dimensional network structure hydrogel with strong wet adhesion, low swelling rate and high toughness is prepared through a photopolymerization reaction. The hydrogel has good biocompatibility, an in-vivo rabbit model proves that an orificium fistulae can be completely sealed through single use or combined suture, a safe and efficient novel biological material is provided for anastomotic fistula treatment, and the hydrogel has important clinical transformation potential.

The invention relates to the technical field of fibers, in particular to a PHBV-containing bio-based high-strength antibacterial fiber and a preparation method thereof.The fiber is obtained by conducting blending and electrostatic spinning on environment-friendly materials including silk fibroin, polyoxyethylene, PHBV and a composite natural antibacterial agent; 1-ethyl-(3-dimethylaminopropyl) carbodiimide hydrochloride, N-hydroxysuccinimide, a composite natural antibacterial agent and carboxymethyl chitosan are used as raw materials to prepare a cross-linking steeping liquor, and the electrostatic spinning fibers are subjected to cross-linking modification treatment in the cross-linking steeping liquor; lignin and hexadecyl trimethyl ammonium bromide are combined for electrostatic assembly to coat a natural antibacterial agent to serve as a pretreatment natural antibacterial agent, 3-chloropropyl-trimethoxysilane serves as a coupling agent, ethylenediamine serves as an amination modification reagent, an amination natural antibacterial agent is obtained, and then a bio-based bacterial adhesion prevention flame-retardant polymer is grafted.

The invention discloses a bi-component micro-nanofiber hydrogel dressing based on a conjugate electrospinning technology, a PSI / PCL micro-nanofiber membrane is prepared from polysuccinimide and polycaprolactone through the conjugate electrospinning technology, the PSI / PCL micro-nanofiber membrane is crosslinked through ethylenediamine, and the PSI-NH2 / PCL bi-component micro-nanofiber hydrogel dressing is obtained. According to the preparation method, a polysuccinimide (PSI) / polycaprolactone (PCL) nanofiber membrane is prepared through a conjugate electrospinning technology and then crosslinked through ethidene diamine (ED), and the PSI-NH2 / PCL micro-nanofiber hydrogel dressing is generated and is excellent in mechanical property, high in swelling and imbibition capacity and good in biocompatibility and further has excellent antibacterial performance and hemostatic performance, and the hydrogel dressing can be applied to the field of medical application. The dressing can be used as an ideal novel wet dressing to achieve the purpose of promoting wound healing.

The invention belongs to the technical field of immunochemiluminescence, and relates to a PAMAM-mediated antibody marker and a synthesis method and application thereof, the PAMAM-mediated antibody marker is composed of an antibody, PAMAM and a marker, amino groups on the surface of the antibody can be converted into sulfydryl groups, and the marker is provided with succinimide groups which can react with the amino groups. The steric hindrance of antigen-antibody reaction is reduced through PAMAM mediation, the labeling proportion is increased to the maximum extent, and a high coupling effect can be achieved with a small feeding proportion.

The invention discloses a preparation method of a carbon fiber-iodine doped carbon quantum dot composite material based on surface modification and chemical crosslinking, and belongs to the technical field of nano composite materials. The material is prepared by carrying out surface treatment on carbon fibers to introduce functional groups, carrying out iodine doping on carbon quantum dots, and directionally connecting complementary functional groups of the carbon fibers and the carbon quantum dots by adopting a bifunctional crosslinking agent (such as 1-ethyl-3-(3-dimethyl propyl) carbodiimide (EDC) / N-hydroxysuccinimide (NHS), glutaraldehyde, hexamethylene diisocyanate and toluene diisocyanate). A stable composite interface is formed through covalent bonds. According to the method, the high CT contrast ratio of the iodine-doped carbon quantum dots is utilized, and in the using process of the carbon fiber, damage and defects in the carbon fiber structure can be detected through a CT imaging method.

The invention belongs to the field of protein hydrogel, and relates to protein adhesive hydrogel for promoting diabetic oral soft tissue injury repair and a preparation method of the protein adhesive hydrogel. The hydrogel is prepared by mixing an aqueous solution of recombinant fusion protein and an aqueous solution of polyethylene glycol bissuccinimide succinate. The sequence of the recombinant fusion protein is as shown in SEQ ID NO: 1: [PAATAVSHTTHAP (VPGKG) 5] 36. The hydrogel disclosed by the invention has good biocompatibility and excellent adhesion performance, can form a lasting antibacterial barrier, and is electrostatically combined with free DNA (Deoxyribonucleic Acid) in NETs, so that inflammatory factor expression induced by the NETs is inhibited, and finally diabetes wound healing is accelerated.

The application relates to the field of biological materials, and provides an anti-freezing hemostatic gel material and a preparation method thereof, which comprises the following steps: S1, preparing an EA complex; the EA complex is prepared by reacting epigallocatechin gallate and 3-acrylamide phenylboronic acid; S2, preparing a gel precursor solution: taking methylacrylated gelatin and acrylic acid in deionized water and heating to completely dissolve; adding an anti-freezing complex and uniformly mixing; subsequently, adding acrylic acid N-succinimidyl ester to obtain the gel precursor solution; the anti-freezing complex is prepared by mixing nanocellulose, proline and glycerol; S3, preparing an anti-freezing hemostatic gel material: mixing and reacting the EA complex, the gel precursor solution, acrylic acid, an initiator and an accelerator to prepare the anti-freezing hemostatic gel material. The anti-freezing hemostatic gel material has good adhesion and high mechanical strength, and can well adapt to the use requirements in a plateau environment.

The invention belongs to the technical field of biological medicine, and discloses a brain-targeted nano drug delivery system, a preparation method and application. According to the invention, dipentaerythritol-polycaprolactone-histidine (DPE-PCL-HIS) is used as a basic drug carrier, and drug curcumin (Cur) molecules are entrapped in a physical embedding manner; and modifying bovine serum albumin (BSA) grafted with a bifunctional intermediate connection compound 4-(N-maleimide methyl) cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt (Sulfo-SMCC) on a precoating layer, and finally connecting an apolipoprotein E mimic peptide as a brain-targeting ligand, so as to construct the brain-targeting bionic protein crown nano drug delivery system, wherein the bovine serum albumin (BSA) is grafted with the bifunctional intermediate connection compound 4-(N-maleimide methyl) cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt (Sulfo-SMCC). According to the prepared brain-targeted nano drug delivery system, apolipoprotein E mimic peptide [RLLRKRLK (PEG2000) RLGWC] is used as a ligand and enters the brain under the transendocytosis action of the apolipoprotein E mimic peptide [RLLRKRLK (PEG2000) RLGWC] and a blood-brain barrier (BBB) surface receptor, the blood-brain barrier permeability of a drug is increased, the brain targeting property and bioavailability of drug-loaded nanoparticles are improved, and the brain-targeted nano drug delivery system has wide application prospects in the aspect of treating brain diseases.

The invention discloses an endoplasmic reticulum targeted lipid peroxidation fluorescent indicator and application thereof, and the indicator introduces a conjugated diolefin structure as a lipid peroxidation recognition unit to obtain a series of BODIPY derivatives with the maximum emission wavelength of 620 nm. A conjugated diene part of the fluorescent probe can be subjected to oxidative cracking under the action of reactive oxygen species, and a conjugated system of the fluorescent probe becomes smaller due to breakage of double bonds, which shows that absorption and emission wavelengths are obviously shortened. Therefore, the LPO process can be monitored through the change of the fluorescence ratio. Meanwhile, hydrophilic succinimide ester sulfonic acid group NHS is introduced as a group reacting with protein, the oil-water coefficient of the compound is moderate, the compound easily penetrates through a cell membrane and reacts with adjacent protein free amino in a short time, the probe can be fixed on the protein of an endoplasmic reticulum through a chemical bond, and the probe can be used for long-time fluorescence imaging research. And long-time real-time tracking is carried out on the movement and form change of the endoplasmic reticulum.

Provided is a hydrogel precursor polymer derived from a poly (asparagine) (PAsPm) comprising cleavable and crosslinkable moieties attached to a pendant carboxylic acid group of the poly (asparagine); and a hydrophilic moiety also attached to a pendant carboxylic acid group, such as an ether-containing moiety obtained by ring opening a polysuccinimide with 2-(2-aminoethoxy) ethanol.

The preparation of water dispersible ceramide conjugates and derivatives of sphingolipid analogues is described. The conjugates and analogues are prepared by reacting a succinimidyl carbonate of a β-Ala derivative with the primary amine of a functionalised spacer. Despite their dispersibility in water, the ceramide conjugates and derivatives of sphingolipid analogues spontaneously incorporate in to the plasma membranes of cells.

The application discloses a long-acting developing medical hydrogel and a preparation method thereof, and belongs to the field of biomedical materials. The long-acting developing medical hydrogel comprises a first component and a second component. The first component comprises multi-arm developing agent amine salt, succinimidyl ester-terminated multi-arm polyethylene glycol and a diluent. The second component is an accelerator solution. The second component is mixed with the first component to form the long-acting developing medical hydrogel through in-situ crosslinking. The long-acting developing medical hydrogel makes up for the shortcoming that conventional hydrogels cannot realize CT developing imaging in the body for a long time. The strength of the hydrogel can be adjusted by adjusting the arm number of the multi-arm developing agent amine salt under the condition that the concentration is unchanged. The multi-arm developing agent amine salt and the succinimidyl ester-terminated multi-arm polyethylene glycol can prolong the effective use time of the succinimidyl ester-terminated multi-arm polyethylene glycol after being mixed, thereby providing sufficient operation time for the operation of a clinician. In addition, the multi-arm developing agent amine salt can resist conventional Co60 irradiation sterilization.

The invention discloses a preparation method of a water treatment agent and the water treatment agent. The preparation method adopts a one-step method for synthesis, and comprises the following steps: mixing polysuccinimide, benzisothiazolinone and alkali, and then adding a solvent for reaction to obtain the water treatment agent. The water treatment agent prepared by the preparation method disclosed by the invention has the effects of scale inhibition and sterilization at the same time, and the efficiency of the water treatment process is improved.

This application belongs to the field of metal corrosion inhibition, specifically providing a neutralizing corrosion inhibitor and its preparation method. A neutralizing corrosion inhibitor comprises the following components by weight: 50-60 parts deionized water, 18-20 parts corrosion inhibitor matrix, 10-14 parts triethanolamine, 3-5 parts benzotriazole, and 6-8 parts ethylene glycol. The corrosion inhibitor matrix of this application is made from raw materials including polysuccinimide, triaminopyrimidine, and tryptophan derivatives. The neutralizing corrosion inhibitor prepared by this application exhibits good thermal stability and excellent corrosion inhibition performance.

Provided are antibody-drug conjugates, methods for preparing them, and uses thereof. The antibody-drug conjugates comprise an antibody, a cytotoxic payload, and a linker of Formula I, wherein the succinimidyl group of the linker of Formula I forms a thioether bond with a thiol group obtained by reduction of the interchain disulfide chain of the antibody, and the carbonyl group in the ester group of the linker is bonded to the amino group of the payload. The antibody-drug conjugates are used in the manufacture of therapeutic agents for the diagnosis, prevention, and treatment of neoplastic diseases.

The invention relates to tear-resistant plush cloth. A composite coating is arranged on the surface of a plush cloth main body; the composite coating comprises a polyacrylate layer and a modified layer, wherein the modified layer is prepared from the following components: phthaloyl glycine hydroxysuccinimide ester, benzoyl peroxide, cyclopentene-1-yl boric acid, a carbon nano tube, dimethyl sulfoxide and deionized water; the invention further relates to a preparation method of the tear-resistant plush fabric. The preparation method comprises the steps of preparation of the modified layer coating liquid and dip-coating operation. By arranging the double-layer composite coating and polyacrylate, the tear resistance, the waterproof function, the antifouling function and the like are improved; the preparation method comprises the following steps: carrying out graft copolymerization on a modified layer which takes phthaloyl glycine hydroxysuccinimide ester as a main material and cyclopentene-1-yl boric acid under the action of benzoyl peroxide; and free radicals decomposed by benzoyl peroxide can attack polyester fiber polyester chains of the plush cloth and are subjected to graft copolymerization with cyclopentene-1-yl boric acid to obtain derivatives carrying boric acid groups, and the derivatives and a polyacrylate layer synergistically improve the tear resistance.

The invention provides a preparation method of N-(4-(tert-butyl) thiazole-2-yl)-3-fluorobenzamide, which comprises the following steps: mixing a compound as shown in a formula I, N, N-diisopropylethylamine and 2-succinimido-1, 1, 3, 3-tetramethylurea tetrafluoroborate for reaction, then adding a compound as shown in a formula II for amidation reaction, and finally obtaining the N-(4-(tert-butyl) thiazole-2-yl)-3-fluorobenzamide. And reacting the N-(4-(tert-butyl) thiazole-2-yl)-3-fluorobenzamide to obtain the N-(4-(tert-butyl) thiazole-2-yl)-3- According to the preparation method provided by the invention, by innovatively changing the reaction sequence, firstly activating the raw materials and then carrying out amidation reaction, the polarity of by-products is successfully changed, the polarity of main by-products is obviously smaller than that of target products, the products are easy to separate, the column chromatography separation efficiency is greatly improved, the yield is increased, and the post-treatment time is shortened.

The invention relates to a preparation method of a cationic aromatic side chain demulsifier, and belongs to the technical field of chemical demulsification, and the preparation method comprises the following steps: S1, preparing used drugs and reagents including polysuccinimide, 1, 4-dibromobutane, N, N-dimethylformamide, N, N-dimethylformamide, N, N-dimethylformamide, N, N-dimethylformamide, N, N-dimethylformamide, N, N- The cleaning agent is prepared from N, N-dimethyl benzylamine, quinoline, triethylamine, dimethyl sulfoxide, acetonitrile, ethylene diamine tetraacetic acid disodium. Dihydrate, anhydrous sodium sulfate, sodium hydroxide, hydrochloric acid, absolute ethyl alcohol, anhydrous calcium chloride, petroleum ether, n-heptane, sodium bicarbonate, complex black T, deionized water, acetone and diethyl ether. S2, preparing required equipment including a double-neck round-bottom bottle provided with a cooling system, heating equipment, cooling equipment, a thermometer, a test tube, a dropper, a beaker and a weighing device; according to the preparation method of the cationic aromatic side chain demulsifier, a relatively good demulsification effect can be displayed at room temperature and in a strong acid environment, and enough surfactant molecules are provided, so that an adsorption layer is formed on the surface of an emulsion, the surface tension is reduced, and an emulsion structure is destroyed.

This invention discloses a wound dressing with photothermal antibacterial, hemocoagulant-promoting, and easily removable properties, its preparation method, and applications, belonging to the field of biomaterials technology. The method includes dissolving sericin in water, then sequentially adding hemoglobin, carbodiimide, and N-hydroxysuccinimide to induce a cross-linking reaction; obtaining a precursor for the composite protein dressing through a mechanochemical cross-linking strategy; pre-cooling the precursor and freeze-drying it to obtain a sericin-hemoglobin dressing; dialyzing the sericin-hemoglobin dressing in water for 2-3 days, and freeze-drying it again to obtain a protein dressing containing only hemoglobin and sericin. The antibacterial dressing prepared by this invention, upon contact with blood, promotes the formation of a dense fibrin membrane, promoting hemostasis while making it easy to remove from the wound site. This wound dressing is entirely composed of protein, exhibits good biocompatibility, and has great development potential.