The invention relates to a flame retardation and antibiosis fabric. A gunny cloth fabric is bonded with a protection coating layer, and the coating layer comprises a-olefin elastomer, polymethyl methacrylate, isoprene rubber, tall oil fatty acid, butyl acetate, allyl sulfide, diethylene glycol diethyl ether, diethylene glycol butyl ether, propiconazole, sodium monofluorophosphate, dodecyl ethoxy sulfobetaine, dimethyl fumarate, cuprous chloride, metatitanic acid, silicon carbide fibers, phenyltriethoxysilane, chromium oxide green, chromium chloride, barium chromate powder, sodium cellulosate, trimethyl phosphate, polyacrylonitrile fibers, dibasic lead stearate, tris(butoxyethyl)phosphate, starch ether, vinyltris(beta-methoxyethoxy)silane, ethylamine, diethylenetriamine, alkylphenol polyoxyethylene and divinyl benzene. The flame retardation and antibiosis fabric has superior flame, acid-alkali, mildew and bacterium resistance, and improved performances.